Abstract：
:We measured with a laser velocimeter granulometric deposit of an aerosol anti-infectious agent, fusafungin, administered with a controlled inhalator. Total drug deposit was determined on the basis of a granulometric spectrum of the polydispered aerosol (mass mean aerodynamic diameter (MMAD) = 2.8 +/- 1.7 microns) and dispersion in the airways was estimated using the Stahlhofen model. We first compared deposits obtained with oral inhalation in 19 normal subjects and 20 patients with chronic obstructive lung disease. Total deposit in the airways of patients with chronic obstructive lung disease (82%) was not significantly different from that in normal subjects (85%). Estimated dispersion in normal airways was 27% in the alveoles, 8.4% in the tracheobronchic region and 23.5% in the extrathoracic regions. We then compared deposits after nasal inhalation in 22 normal subjects and 21 patients with rhinitis: nasal deposit was significantly greater in patients with rhinitis (54.5%) than in controls (44.7%). We conclude that such an inhalator can be adapted for local treatment of ENT infections and upper respiratory infections. Deposit is not modified in case of obstructive bronchopathy.
journal_name
Rev Pneumol Clinjournal_title
Revue de pneumologie cliniqueauthors
Bouchikhi A,Becquemin MH,Bertholon JF,Roy M,Harpey C,Stahlhofen W,Nizar Zsubject
Has Abstractpub_date
1994-01-01 00:00:00pages
309-15issue
6eissn
0761-8417issn
1776-2561journal_volume
50pub_type
杂志文章abstract：:The observation of 3 cases has prompted the authors to review the characteristics of vascular abnormalities that may be found in Behçet's disease. These lesions, the frequency of which has diversely been estimated, involve the veins more often than the arteries. Arterial lesions occur, after a varying length of time, ...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：1990-01-01 00:00:00
abstract：:Pleomorphic carcinoma is a rare malignancy belonging to the family of nonsmall cell lung cancers. A 40-year-old man, a smoker, was hospitalized for thoracic pain and dry cough with a deteriorating general condition. The imaging showed a "drop ball" of both lungs. The pathological evidence was obtained by lung biopsy u...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/j.pneumo.2010.04.002
更新日期：2011-06-01 00:00:00
abstract：INTRODUCTION:Dermatofibrosarcoma protuberans (Darrier-Ferrand sarcoma, DFSP) is an uncommon tumor. This sarcoma has a tendency to local recurrence, requiring a wide surgical resection. OBSERVATION:We report herein two cases of patients presenting with recurrent dermatofibrosarcoma protuberans after several surgical re...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/j.pneumo.2016.09.005
更新日期：2017-04-01 00:00:00
abstract：:A necroscopic study, conducted in the Pathology Department of the Centre Hospitalier Universitaire (CHU) de Treichville in Abidjan, included 70 seropositive subjects who died in the Pneumophtisiology Department. We attempted to determine the different pulmonary affections occurring during infection with the human immu...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:Acute chest syndrome is a frequent complication of sickle cell disease. This syndrome is characterized by recent infiltrate on chest X-ray with chest pain or fever or dyspnea. We report the case of a 26-year-old man in whom an acute chest syndrome with fat embolism was the inaugural sign of sickle cell disease. This r...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/s0761-8417(06)75439-6
更新日期：2006-06-01 00:00:00
abstract：:Approximately 30% of small-cell bronchogenic cancers are associated with hypersecretion of ACTH. However, in most cases, there is no clinical expression. When a paraneoplastic Cushing syndrome occurs, it is an independent factor of poor prognosis. Management is extremely complex. Treatment must be based on high dose i...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：1999-04-01 00:00:00
abstract：:Multiresistant tuberculosis has been recognized since the advent of triple-drug therapy with isoniazid, streptomycin and PAS in the fifties, but the recently observed strains of Mycobacterium tuberculosis resistant both to isoniazid and to rifampicin, the rapid spread of the infection and the development of severe dis...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：1994-01-01 00:00:00
abstract：:Inflammation aggravates respiratory impairment in patients with cystic fibrosis. It plays an essential role in the genesis of bronchial hyperreactivity. Corticosteroids are the predominant therapeutic agents used. The importance of bronchial hyperreactivity in cystic fibrosis is correlated with disease severity. Treat...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:Mediastinal hemangiomas are rare tumours occurring more often in children and young adults. A new case is reported in a 21 years old male who had an anterior mediastinal mass detected on a routine chest roentgenogram. Pre-operative investigations including CT, venous digital angiography, MRI did not aid in the right d...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：1990-01-01 00:00:00
abstract：:Pneumonias occupy a prominent situation among lower respiratory tract infections where they are remarkable for their potential mortality and for our relative knowledge of the responsible micro-organisms. Analysis and synthesis of each series published must answer several questions, such as: what are the lung diseases ...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：1992-01-01 00:00:00
abstract：:Obstructive sleep apnea, obesity-related hypoventilation - a hypoventilation which is independent of apneas and increased by sleep -, and hypoxemia related to local ventilation-perfusion disorders are the main mechanisms of respiratory failure occurring during acute respiratory decompensation following an often minima...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：2002-04-01 00:00:00
abstract：:Mature teratoma is the most frequent primary germ-cell tumor occurring in the mediastinum. These tumors present characteristic mature cells derived from all three types of embryogenesis tissues. We report two cases. The typical presentation is a cyst-like noninvasive, heterogeneous and calcified formation in the anter...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1999-06-01 00:00:00
abstract：:Primary tumors are relatively rare in the pleura. Histological types include mesothelioma, epitheliod, biphasic or sarcomatoid tumors as well as primary lymphoma and mesenchymatous tumors which include solitary fibrous tumor, epithelioid hemangioendothelioma and angiosarcoma and synovialosarcoma. We detail here the ne...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：10.1016/s0761-8417(06)75420-7
更新日期：2006-04-01 00:00:00
abstract：:Congenital tuberculosis is an uncommon but probably underestimated disease. All cases occurring in developing countries are not published. Twenty-nine cases have been published in the English literature since 1980. The diagnosis of congenital tuberculosis is different from post-natal tuberculosis and is based on recen...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1998-09-01 00:00:00
abstract：:Ten subjects with chronic bronchitis with relatively severe bronchial obstruction and, in most cases, severe distension underwent strengthening of their respiratory muscles at home by an additional respiratory resistance load for 10 minutes 3 times a day for one month. All of these subjects obtained an increased endur...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：:The authors report 2 cases of acute hepatic failure secondary to a pulmonary embolism, the [atypical] symptomatology of which considerably interfered with diagnosis. A review of the literature confirms the rarity of embolic pathology as causing acute cardiac liver. The authors emphasize the importance of echotomograph...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Nutritional status assessment during the comprehensive management of patients treated for cancer is becoming increasingly necessary. Various data are currently available which show a relationship between the nutritional status and certain morbidity-mortality parameters. In contrast, there is a paucity of data concerni...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：10.1016/j.pneumo.2008.03.002
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine the clinical, radiographic, and ultrasonographic aspects of mediastinal nodal tuberculosis and ascertain its clinical course in the era of HIV infection. PATIENTS AND METHODS:We reviewed retrospectively 39 patients referred to the Ouédraogo Yalgado National Hospital...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：2001-02-01 00:00:00
abstract：:Complications observed after lung transplantation are well described for the different indications. Certain complications are specifically observed in patients with cystic fibrosis who have reached the stage of major respiratory failure. The most specific complications result from digestive tract manifestations of the...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：2002-12-01 00:00:00
abstract：:Inoperable non- microcellular primary bronchial carcinomas have been reputed up to now to be chemo-resistant. The introduction of Cis-platinum into a polychemotherapy protocol leads to revision of this concept. The authors report the preliminary results of a polychemotherapy protocol (including Cis-platinum, Vindesine...
journal_title：Revue de pneumologie clinique
pub_type： 临床试验,杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：BACKGROUND:Tuberculosis and human immunodeficiency virus infection are two major public health problems in sub-Saharan Africa. The aim of this study was to determine the prevalence of HIV infection in all clinical forms of TB and investigate the effects of HIV status on the evolution of tuberculosis. PATIENTS AND METH...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/j.pneumo.2012.10.001
更新日期：2012-12-01 00:00:00
abstract：:The authors report a case of AIDS revealed by pleuropulmonary cryptococcosis. The infection was diagnosed by culture of the pleural fluid and confirmed by microscopic examination of the cerebrospinal fluid, using Indian ink as stain. Apyrexia and return to normal of chest radiography were obtained with oral fluconazol...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：1991-01-01 00:00:00
abstract：:Muscular metastasis from primary bronchial carcinoma are rare. We report seven cases with different clinical features. In most cases, these metastasis first manifested as a painful mass and revealed the cancer. Localisation of muscular metastasis was assessed by various imaging techniques (RMI, CT scan and ultrasonogr...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/j.pneumo.2010.09.001
更新日期：2011-04-01 00:00:00
abstract：:We report a new case of localized primary tracheobronchial amyloidosis revealed by haemoptysis and effort dyspnea. The CT scan image was a homogeneous and circumferential thickening of the bronchial wall measuring 282 on the Hounsfield scale. At magnetic resonance imaging the amyloid substance was a slightly less inte...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：
更新日期：1988-01-01 00:00:00
abstract：:Nicardipine is a commonly used anti-hypertensive drug for acute situations. We report the case of a 55-year-old man with hypoxemic pneumonia, who presented a worsening of his hypoxia secondary to the injection of this calcium channel inhibitor (CCI). This side effect was probably caused by inhibition of hypoxic pulmon...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/j.pneumo.2011.08.003
更新日期：2012-06-01 00:00:00
abstract：INTRODUCTION:Pneumocystis jiroveci (PJ) infection is rare in infants and is suggestive of primary or secondary immunodeficiency. We report on a case of severe PJ pneumonia in an immunocompetent infant after prolonged corticosteroid treatment. CASE REPORT:A 5 1/2 month-old girl presented with hypoxemic respiratory dist...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/j.pneumo.2008.06.012
更新日期：2008-10-01 00:00:00
abstract：:The authors present 52 cases of neurological complications of bronchial cancer including 35 cases of non-tumoral manifestations. They stress the frequency and the severity of these complications which are dominated by cerebral vascular accidents and describe the pathogenic features of this particular complication. The...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Mediastinoscopy is an invasive technique used to explore the anterior and upper mediastinum. The axial mediastinum and its lymph nodes are explored through the cervical approach, and the pulmonary vessels and anterior mediastinal lymph nodes through the parasternal approach. Bronchial carcinomas which extend to the me...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:The prevalence of smoking in France remains very high compared to other developed Western countries. The management of smoking in smokers is often limited to nicotinic substitution, whether medicated or linked to the use of electronic cigarettes or varenicline and advices more or less reliable or helpful. This strateg...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章,评审
doi：10.1016/j.pneumo.2017.09.005
更新日期：2017-12-01 00:00:00
abstract：INTRODUCTION:Lung cancer is the leading cause of death by cancer and cirrhosis is the fourteenth, all causes included. Surgery increases postoperative risks in cirrhotic patients. Our purpose was to analyze this point in lung cancer surgery. METHODS:We collected, among 7162 patients, the data concerning those operated...
journal_title：Revue de pneumologie clinique
pub_type： 杂志文章
doi：10.1016/j.pneumo.2014.09.006
更新日期：2015-02-01 00:00:00
