Abstract:
:Pleomorphic carcinoma is a rare malignancy belonging to the family of nonsmall cell lung cancers. A 40-year-old man, a smoker, was hospitalized for thoracic pain and dry cough with a deteriorating general condition. The imaging showed a "drop ball" of both lungs. The pathological evidence was obtained by lung biopsy under scanographic control. The presence of supraclavicular and abdominal nodes classified the tumour as stage IV. The patient received six cycles of first-line chemotherapy associating cisplatin and vinorelbine. However, the disease continued to progress and distant metastases were observed. The patient died 6 months after the diagnosis. Pleomorphic carcinoma is identified by purely histological criteria: the concomitant presence of malignant epithelial and homologous sarcomatoid spindle-cell components. Like the other nonsmall cell lung cancers, the treatment is primarily surgical, and the invasive nature of this tumour makes it very difficult. Pleomorphic carcinoma has a poorer prognosis than conventional nonsmall cell lung cancers despite surgery, irradiation and chemotherapy, because relapse occurs early.
journal_name
Rev Pneumol Clinjournal_title
Revue de pneumologie cliniqueauthors
Tazi EM,Essadi I,Arifi S,Ichou M,Errihani Hdoi
10.1016/j.pneumo.2010.04.002subject
Has Abstractpub_date
2011-06-01 00:00:00pages
163-6issue
3eissn
0761-8417issn
1776-2561pii
S0761-8417(10)00112-4journal_volume
67pub_type
杂志文章abstract::We report the case of a 46-year-old-woman who presented with anosmia and nasal obstruction. Primary nasal tuberculosis was discovered. Primary nasal tuberculosis is very rare. Women are more touched than men. Symptomatology is often unilateral with nasal obstruction, anterior rhinorrhea or epistaxis. Diagnosis relies ...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:10.1016/j.pneumo.2014.02.001
更新日期:2014-10-01 00:00:00
abstract::Over a 6 years' period (1980-1986), 272 patients with chronic respiratory disease were admitted for respiratory failure to the same intensive care unit. The series was characterized by the high mean age of the patients (69.3 years) and by the high proportion of those who were ventilated (75%); 33.7% of the patients di...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::A case of Carrington's chronic eosinophilic pneumonia associated with bronchocentric granulomatosis in a young asthmatic woman is reported. Among the numerous forms of "eosinophilic lung", the characteristic features of these two diseases in asthmatic patients are briefly described. Concerning the association, the aut...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::Breathlessness induced by external resistances (diaphragms with orifice size of 20, 15, 10, 7.5 and 5 mm) introduced in the ventilatory circuit of a spirometer and the corresponding parameters of a maximal flow-volume loop have been studied. 10 healthy subjects (5 men, 5 women), free from any acute or chronic cardiore...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Constrictive pericarditis was diagnosed in four patients who presented respiratory impairment and pleural effusion, associated with right ventricular failure in two. The cause was probable tuberculosis in two cases, post-irradiation lesions in one and unknown in one. The diagnosis was suspected due to the normal heart...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1998-02-01 00:00:00
abstract::Primary tumors are relatively rare in the pleura. Histological types include mesothelioma, epitheliod, biphasic or sarcomatoid tumors as well as primary lymphoma and mesenchymatous tumors which include solitary fibrous tumor, epithelioid hemangioendothelioma and angiosarcoma and synovialosarcoma. We detail here the ne...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:10.1016/s0761-8417(06)75420-7
更新日期:2006-04-01 00:00:00
abstract::Mature teratoma is the most frequent primary germ-cell tumor occurring in the mediastinum. These tumors present characteristic mature cells derived from all three types of embryogenesis tissues. We report two cases. The typical presentation is a cyst-like noninvasive, heterogeneous and calcified formation in the anter...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract::The prevalence of smoking in France remains very high compared to other developed Western countries. The management of smoking in smokers is often limited to nicotinic substitution, whether medicated or linked to the use of electronic cigarettes or varenicline and advices more or less reliable or helpful. This strateg...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:10.1016/j.pneumo.2017.09.005
更新日期:2017-12-01 00:00:00
abstract::Autopsies were performed in the Pathology Department of the Treichville University Hospital, Abidjan, Ivory Coast in 70 HIV infected subjects who had died in the Department of Pneumophtisiology. The prevalence of Pneumocystis carinii pneumonia was determined. None of the patients had received prophylaxis against P. ca...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Castleman disease is a rare lymph nodes disease whose name covers different clinical presentations. The most frequent histology is the hyaline vascular localized form. In this case, Castleman disease occurs in young adults, and is localized to the mediastinum in one third of the cases. The disease is often asymptomati...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:10.1016/j.pneumo.2013.09.001
更新日期:2013-12-01 00:00:00
abstract::Knowledge of asthma and its treatment were evaluated in a survey of 1,000 asthmatics using a self-questionnaire with closed questions. As far as the disease was concerned, 87.4% of patients knew that the bronchi were the pathological organ and 70.6% that the disease persisted between attacks. Overall knowledge of the ...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
abstract::The authors present 52 cases of neurological complications of bronchial cancer including 35 cases of non-tumoral manifestations. They stress the frequency and the severity of these complications which are dominated by cerebral vascular accidents and describe the pathogenic features of this particular complication. The...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::We report a case of Klebsiella pneumoniae medisatinitis secondary to a retrophyarygeal abscess in a 40-year-old patient. The patient was treated with antibiotics and pleural drainage. Surgery was not necessary and the clinical course was favorable. We recall the pathophysiological and clinical aspects of this now unco...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::Large calcium deposits can occur in neuroendocrine tumours of the bronchi and have been observed more frequently with the development of tomodensitometry which is now used for the diagnosis of calcified lung tumours including neuroendocrine tumours. The knowledge of such calcified images should not however mask the po...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:1995-01-01 00:00:00
abstract::Nutritional status assessment during the comprehensive management of patients treated for cancer is becoming increasingly necessary. Various data are currently available which show a relationship between the nutritional status and certain morbidity-mortality parameters. In contrast, there is a paucity of data concerni...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:10.1016/j.pneumo.2008.03.002
更新日期:2008-04-01 00:00:00
abstract::Inflammatory pseudo-tumors of the lung are generally unifocal lesions with a benign prognosis. The pathogenesis is unknown. We report the case of a 71-year-old man who underwent exploration for dyspnea and chest pain associated with weight loss and a heterogeneous opacity in the lingula. This radiological and clinical...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/s0761-8417(04)72085-4
更新日期:2004-02-01 00:00:00
abstract:UNLABELLED:The management of localized non-small cell lung cancer (NSCLC) has been modified over the last decades, with induction therapies being increasingly recommended as a prerequisite to surgical resection. However, the relative impact of chemo- and chemoradiotherapy on tumours' pathology and patients' survival is...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/j.pneumo.2013.12.008
更新日期:2014-02-01 00:00:00
abstract::Tracheobronchomegaly is defined as a dilatation of the trachea and the large bronchi. It may occur as a familial condition or in association with a connective tissue disease, e.g. Ehlers-Danlos syndrome. Tracheobronchomegaly occurs late in adults. The predominant symptoms are bronchial irritation and recurrent broncho...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND:Surgical resection of pulmonary aspergilloma is associated with symptoms control, complications prevention, and improved survival, given that the disease is localized and the patient fit enough to undergo surgery. In these operable forms, the impact of perioperative antifungal therapy remains controversial. ...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/j.pneumo.2014.08.002
更新日期:2014-12-01 00:00:00
abstract::Studies of acute exacerbations of chronic bronchitis (EXCB) included in the approval documents of levofloxacin (LVF) were reviewed in light of the good conditions of use defined by the French marketing approval and the AFSSAPS recommendations. The approval documents included two American studies comparing LVF 500 mg/d...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/s0761-8417(04)72112-4
更新日期:2004-11-01 00:00:00
abstract::Asthma is a very common disease and may be encountered in pregnant women. The physiological changes which accompany pregnancy, as well as the risks of drug teratogenicity and drug interactions make it necessary to take certain therapeutic precautions. Following a review of the specific respiratory physiological change...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Thymolipoma is an uncommon benign tumor of the thymus. Asymptomatic, it is an incidental discovery. Pathogenesis remains controversial. We report a new case in a 36-year-old woman that was discovered on a chest x-ray ordered for pneumonia. The MRI findings suggested the diagnosis which was confirmed at the pathology e...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract::Acute chest syndrome is a frequent complication of sickle cell disease. This syndrome is characterized by recent infiltrate on chest X-ray with chest pain or fever or dyspnea. We report the case of a 26-year-old man in whom an acute chest syndrome with fat embolism was the inaugural sign of sickle cell disease. This r...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/s0761-8417(06)75439-6
更新日期:2006-06-01 00:00:00
abstract::Mediastinal hemangiomas are rare tumours occurring more often in children and young adults. A new case is reported in a 21 years old male who had an anterior mediastinal mass detected on a routine chest roentgenogram. Pre-operative investigations including CT, venous digital angiography, MRI did not aid in the right d...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::Inoperable non- microcellular primary bronchial carcinomas have been reputed up to now to be chemo-resistant. The introduction of Cis-platinum into a polychemotherapy protocol leads to revision of this concept. The authors report the preliminary results of a polychemotherapy protocol (including Cis-platinum, Vindesine...
journal_title:Revue de pneumologie clinique
pub_type: 临床试验,杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::We measured with a laser velocimeter granulometric deposit of an aerosol anti-infectious agent, fusafungin, administered with a controlled inhalator. Total drug deposit was determined on the basis of a granulometric spectrum of the polydispered aerosol (mass mean aerodynamic diameter (MMAD) = 2.8 +/- 1.7 microns) and ...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::The increasing precision of exercise testing modalities has contributing to making it an excellent means of evaluating functional impairment in dyspnea patients. It has become an indispensable diagnostic tool. Interpretation of data acquired during an exercise test depends on the reliability of data collection and the...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:1997-01-01 00:00:00
abstract::Multiresistant tuberculosis has been recognized since the advent of triple-drug therapy with isoniazid, streptomycin and PAS in the fifties, but the recently observed strains of Mycobacterium tuberculosis resistant both to isoniazid and to rifampicin, the rapid spread of the infection and the development of severe dis...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract::When small and inextensive these tumours are rare and often surgical; when extensive they are usually unresectable. Owing to the late development of dyspnoea and to the frequent normality of thoracic radiography the endoscopic diagnosis is seldom made at an early stage, which explains why these tumours are often regar...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Assessment of daily physical activity (DPA) is a major element in the development of respiratory rehabilitation. The aim of this study was to evaluate the DPA and the daily energy expenditure (DEE) in adult patients with cystic fibrosis. Thirty adult patients (16 women, 14 men, mean age 27.1±8.4 years) with cystic fib...
journal_title:Revue de pneumologie clinique
pub_type: 杂志文章
doi:10.1016/j.pneumo.2012.11.006
更新日期:2013-02-01 00:00:00