[Nicardipine induced hypoxia: role of hypoxic pulmonary vasoconstriction].

Abstract:

:Nicardipine is a commonly used anti-hypertensive drug for acute situations. We report the case of a 55-year-old man with hypoxemic pneumonia, who presented a worsening of his hypoxia secondary to the injection of this calcium channel inhibitor (CCI). This side effect was probably caused by inhibition of hypoxic pulmonary vasoconstriction. Effects of CCI on pulmonary vessels are well-known. They don't induce clinically relevant hypoxemia in patients without acute pulmonary pathology. This case report shows that nicardipine can severely worsen haematosis of patients with acute hypoxia. CCI should probably not be used in such patients.

journal_name

Rev Pneumol Clin

authors

Cotte J,D'Aranda E,Esnault P,Bordes J,Meaudre E

doi

10.1016/j.pneumo.2011.08.003

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

221-4

issue

3

eissn

0761-8417

issn

1776-2561

pii

S0761-8417(11)00122-2

journal_volume

68

pub_type

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