The use of mesenchymal stem cells in bladder augmentation.

Abstract:

PURPOSE:To compare integration of bladder acellular matrix (BAM) with the bladder when seeded with mesenchymal stem cells (MSC) and when MSC are injected intravenously (IV). METHODS:MSCs were isolated from bone marrow of EPM-1 Wistar male rats. Female rats were distributed into: Group A-BAM augmentation; Group B-BAM augmentation and MSCs IV administered; Group C-BAM-MSC seeded augmentation. Animals were killed on postoperative days 7, 14 and 28. Morphological analyses were performed using hematoxylin and eosin and Masson's trichrome, in addition to immunohistochemical staining with α-SMA and neurofilament for assessment of tissue repair. RNAm expression of the SRY gene was used to mark MSCs in the rats killed on postoperative day 28. RESULTS:The muscle layer was best repaired in Groups B and C. No difference in the repair of the urothelium in the animals in any of the three groups was found. Group B presented the smallest inflammatory reaction and the best neural repair on postoperative day 28. None of the animals examined had MSCs in their bladder graft. CONCLUSION:The MSCs were able to improve repair of the muscle layer and when injected intravenously, they were noted to initiate the neuronal regeneration process.

journal_name

Pediatr Surg Int

authors

Leite MT,Freitas-Filho LG,Oliveira AS,Semedo-Kuriki P,Laks M,Arias VE,Peixoto PS

doi

10.1007/s00383-014-3465-2

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

361-70

issue

4

eissn

0179-0358

issn

1437-9813

journal_volume

30

pub_type

杂志文章
  • Utility of PAS and β-catenin staining in histological categorisation and prediction of prognosis of hepatoblastomas.

    abstract:AIMS:The aim of this study was to assess the usefulness of PAS, β-catenin and Ki-67 in categorising hepatoblastomas (HBs) and their significance in predicting prognosis. In addition, we have also documented the various chemotherapy induced histologic changes in HBs. METHOD:In this retrospective observational study of ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-017-4115-2

    authors: Bera G,Das RN,Roy P,Ghosh R,Islam N,Mishra PK,Chatterjee U

    更新日期:2017-09-01 00:00:00

  • Successful treatment of severe refractory anastomotic stricture in an infant after esophageal atresia repair by endoscopic balloon dilation combined with systemic administration of dexamethasone.

    abstract::A boy with a history of esophageal atresia repair received an esophagoesophagostomy at 14 months for a severe refractory anastomotic stricture, which had already required repeated balloon dilation with intralesional dexamethasone injection. Anastomotic leakage and stricture was again evident after the second surgery, ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-009-2367-1

    authors: Hishiki T,Kouchi K,Saito T,Terui K,Sato Y,Mitsunaga T,Nakata M,Yoshida H

    更新日期:2009-06-01 00:00:00

  • A report of renal artery embolization for hematuria facilitating neoadjuvant chemotherapy in an unresectable malignant renal rhabdoid tumor.

    abstract::Malignant rhabdoid tumor (MRT) of the kidney is a rare pediatric tumor characterized by its aggressive nature and chemoresistance. Our patient had MRT of the right kidney with tumor thrombus in the renal vein, inferior vena cava, and right atrium. He developed transfusion-resistant hematuria. This was successfully con...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-013-3260-5

    authors: Sharma R,Kitchen BJ,Mody R,Chamdin A,Bruch S,Jasty R

    更新日期:2013-05-01 00:00:00

  • Tracheoesophageal fistula in the developing world: are we ready for thoracoscopic repair?

    abstract:PURPOSE:Tracheoesophageal fistula (TEF) is a bellwether for a country's ability to care for sick newborns. We aim to review the existing literature from low- and middle-income countries in regard to management of those newborns and the possible approaches to improve their outcomes. METHODS:A review of the existing Eng...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,评审

    doi:10.1007/s00383-020-04639-7

    authors: Alslaim HS,Banooni AB,Shaltaf A,Novotny NM

    更新日期:2020-05-01 00:00:00

  • Separation of ischiopagus tetrapus conjoined twins in the Sultanate of Oman.

    abstract::Premature male ischiopagus tetrapus twins weighing 2.2 kg were born unexpectedly. They required initial ventilation for respiratory distress syndrome and an emergency laparotomy for intestinal obstruction at 10 days of age. At 8 months of age, formal separation was carried out. Primary skin closure was possible withou...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/BF01372144

    authors: Freeman NV,Fahr J,Al-Khusaiby S

    更新日期:1997-04-01 00:00:00

  • Perforated tubular duplication of the transverse colon: a rare cause of meconium peritonitis with prenatal diagnosis.

    abstract::The transverse colon is an exceptional location of intestinal duplication. Perforated duplications are rarely described in neonates. Meconium peritonitis (MP) can originate from prenatal perforated intestinal duplication. The authors report a case of a baby girl with prenatal diagnosis of MP. Rapid worsening of clinic...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-004-1349-6

    authors: Piolat C,N'die J,Andrini P,Althuser M,Jouk PS,Jacquier C,Dyon JF

    更新日期:2005-02-01 00:00:00

  • Cystic teratoma of the pancreas.

    abstract::Cystic teratoma of the pancreas is an extremely rare entity: only 11 cases have been described so far in the world literature. We report the 12th case, in a 4-month-old girl. ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/BF00183759

    authors: Das PC,Radhakrishna K,Rao PL

    更新日期:1996-03-01 00:00:00

  • Bladder bowel dysfunction in children with Down's syndrome.

    abstract:INTRODUCTION:Bladder Bowel Dysfunction (BBD) has been described in patients with Down's Syndrome (DS). Our aim was to report the incidence, demographics, presentation, complications and management of the bladder in DS patients with BBD. METHODS:A systematic review was performed using PRISMA guidelines and search terms...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-020-04682-4

    authors: Bhatt NR,Murchison L,Yardy G,Kulkarni M,Mathur AB

    更新日期:2020-07-01 00:00:00

  • In-vitro uptake of radioactive lipiodol I-131 and I-125 by hepatoblastoma: implications for targeted radiotherapy.

    abstract::Lipiodol, a stable iodine addition product of fatty ethyl esters derived from poppyseed oil, has been used as a vehicle for targeted cytotoxic or radiotherapeutic treatment in adults with unresectable hepatocellular carcinoma and in a few children with advanced hepatoblastoma (HB). Prolonged retention of lipiodol by t...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s003830100004

    authors: Towu E,Boxer G,Begent R,Zweit J,Spitz L,Hobbs K,Winslet M

    更新日期:2001-11-01 00:00:00

  • Female pediatric and adolescent genitalia trauma: a retrospective analysis of the National Trauma Data Bank.

    abstract:PURPOSE:Pediatric genitalia injury represents 0.6% of all pediatric trauma. It is crucial for providers to understand whether pediatric patients are at risk for violent mechanisms, such as rape, assault, or other abuse. Therefore, we sought to perform a large database analysis of pediatric and adolescent female genital...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-020-04736-7

    authors: Fan SM,Grigorian A,Chaudhry HH,Allen A,Sun B,Jasperse N,Albertson S,Nahmias J

    更新日期:2020-10-01 00:00:00

  • Extrapleural thoracoscopic repair of esophageal atresia with tracheoesophageal fistula.

    abstract::Traditionally, open repair of esophageal atresia (EA) with tracheoesophageal fistula (TEF) required thoracotomy. Innovations in minimal access surgery have created a thoracoscopic technique resulting in violation of the pleural space. Most pediatric surgeons favor an extrapleural approach for open repair. We present a...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-005-1366-0

    authors: Tsao K,Lee H

    更新日期:2005-04-01 00:00:00

  • Fecal and urinary continence after scope-assisted anorectovaginoplasty for female anorectal malformation.

    abstract:AIM:We assessed continence after scope-assisted anorectovaginoplasty (SARVP) for female anorectal malformation (FARM). METHODS:Five FARM cases were assessed; cases 1 and 2: cloacal malformation; case 3: urogenital sinus, and rectovestibular fistula (RF); case 4: RF, absent vagina, and sacral anomaly; case 5: covered c...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-012-3141-3

    authors: Yamataka A,Goto S,Kato Y,Koga H,Lane GJ,Okazaki T

    更新日期:2012-09-01 00:00:00

  • Concealed penis.

    abstract::A small phallus causes great concern regarding genital adequacy. A concealed penis, although of normal size, appears small either because it is buried in prepubic tissues, enclosed in scrotal tissue penis palmatus (PP), or trapped due to phimosis or a scar following circumcision or trauma. From July 1978 to January 20...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-002-0770-y

    authors: Radhakrishnan J,Razzaq A,Manickam K

    更新日期:2002-12-01 00:00:00

  • Does noncomplicated acute appendicitis cause bacterial translocation?

    abstract::It is unknown whether noncomplicated acute appendicitis cause bacterial translocation. In this study, we aimed to test development of the bacterial translocation in the patients who were operated for acute appendicitis. In this prospective study, 10 control patients who underwent elective operations because of other r...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-007-1899-5

    authors: Aslan A,Karaveli C,Ogunc D,Elpek O,Karaguzel G,Melikoglu M

    更新日期:2007-06-01 00:00:00

  • Pyloric atresia associated with epidermolysis bullosa, malrotation, and high anorectal malformation with recto-urethral fistula: a report of successful management.

    abstract::Pyloric atresia (PA) is an uncommon anomaly that may be associated with many other congenital anomalies, the commonest of which is junctional epidermolysis bullosa (JEB). Most of the cases of PA associated with JEB (Herlitz syndrome) reported have been fatal. A case of PA associated with JEB, malrotation, and a high a...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s003830050572

    authors: Agarwala S,Goswami JK,Mitra DK

    更新日期:1999-01-01 00:00:00

  • Morphogenesis of the human external male genitalia.

    abstract::The morphogenesis of the external genitalia of human fetuses (16-250 mm crown-rump [CR] length, 6-26 weeks of gestation) obtained after medical termination of pregnancy were studied. Differential development (male/female) started after 50 mm CR length (9 weeks). At that time the external genitalia consisted of a cylin...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/BF01076950

    authors: Ammini AC,Sabherwal U,Mukhopadhyay C,Vijayaraghavan M,Pandey J

    更新日期:1997-07-01 00:00:00

  • Surgical treatment for rebleeding caused by bypass failure after Rex shunt: re-Rex shunt or Warren shunt?

    abstract:PURPOSE:Although Rex shunt is an effective treatment for extrahepatic portal venous obstruction (EHPVO), 4-20% children develop rebleeding postoperatively. This study was used to evaluate the surgical treatment of rebleeding after Rex shunt in our center. METHOD:From June 2008 to Jan 2017, 12 of 122 children with EHPV...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-018-4246-0

    authors: Zhang JS,Li L,Cheng W

    更新日期:2018-05-01 00:00:00

  • Congenital lumbar hernia.

    abstract::Congenital lumbar hernia (CLH) is a rare anomaly with only 45 cases reported in the English-language literature. This paper describes nine patients with CLH treated in our unit. Unusual features included the relatively high incidence of inferior lumbar hernia, presentation at the age of 6 years in one case, and an ass...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s003830050048

    authors: Wakhlu A,Wakhlu AK

    更新日期:2000-01-01 00:00:00

  • Evaluation of developing rat testis by phosporus 31P magnetic resonance spectroscopy and DNA flowcytometry.

    abstract::For the assessment of germ-cell maturation of the seminiferous tubules, DNA flowcytometry is a rapid and sensitive method. Phosporus 31P magnetic resonance spectroscopy (MRS) is a non-invasive alternative that demonstrates the metabolic status of the testis, reflecting the type and relative proportion of germ cells in...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s003830100602

    authors: Srinivas M,Degaonkar M,Gupta DK,Raghunathan P,Das SN,Mitra DK

    更新日期:2001-05-01 00:00:00

  • The outcomes of a frenulotomy on breastfeeding infants followed up for 3 months at Thammasat University Hospital.

    abstract:PURPOSE:To study the effects of frenulotomy on nipple pain, latch and the success in exclusive breastfeeding (EBF) at 3-month follow-up. METHODS:A prospective cross-sectional study of 328 mother-infant pairs with both tongue-tie and breastfeeding problems was performed. Nipple pain and latch were evaluated using numer...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-016-3952-8

    authors: Wakhanrittee J,Khorana J,Kiatipunsodsai S

    更新日期:2016-10-01 00:00:00

  • Bone marrow mononuclear stem cell infusion improves biochemical parameters and scintigraphy in infants with biliary atresia.

    abstract:PURPOSE:To evaluate early postoperative results in a case controlled study following clinical use of stem cells in extrahepatic biliary atresia (EHBA). METHODS:From July 2005 to March 2008, 30 cases of suspected EHBA were divided in two groups in an intervention study. Group A received autologous mononuclear bone marr...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-010-2712-4

    authors: Sharma S,Kumar L,Mohanty S,Kumar R,Datta Gupta S,Gupta DK

    更新日期:2011-01-01 00:00:00

  • The area and attachment abnormalities of the gubernaculum in patients with undescended testes in comparison with those with retractile testes.

    abstract:PURPOSE:In order to evaluate the gubernaculum (GN) abnormalities quantitatively in patients with undescended testes (UDT), the area and attachment site of the gubernaculum were evaluated. PATIENTS AND METHODS:Sixty-seven testes from 61 patients with an undescended testis treated in the past 11 years at our institution...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-014-3597-4

    authors: Kubota M,Nakaya K,Arai Y,Ohyama T,Yokota N,Nagai Y

    更新日期:2014-11-01 00:00:00

  • Delayed complete repair of exstrophy with testosterone treatment: an alternative to avoid glans complications?

    abstract:PURPOSE:Since 1999, complete primary repair of exstrophy has represented a valid alternative in the treatment of exstrophy patients, offering one- stage reconstruction for all components of this malformation in newborns. The vast majority of cases are currently approached within 48/72 h of life, and risk of vascular in...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-010-2745-8

    authors: Zaccara A,De Gennaro M,Di Lazzaro A,Capolupo I,Bozza P,Ragni A,Bagolan P

    更新日期:2011-04-01 00:00:00

  • Long-term outcomes of children undergoing video-assisted gastrostomy.

    abstract:PURPOSE:The aims of this study were to assess the short- and long-term complication rates after video-assisted gastrostomy (VAG), the effects of age and gender on long-term complications and the effect of duration of gastrostomy tube retention on the need for gastroraphy when the gastrostomy device was removed. METHOD...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-016-4001-3

    authors: Salö M,Santimano A,Helmroth S,Stenström P,Arnbjornsson EÓ

    更新日期:2017-01-01 00:00:00

  • No incidence of port-site recurrence after endosurgical procedure for pediatric malignancies.

    abstract::Port-site recurrence (PSR) following laparoscopic procedures has been an unpredictable complication in adult cancer patients; however, no data exist about this phenomenon in the pediatric field. The aim of this study was to determine whether PSR, following endosurgical procedure for malignancies, is a typical complica...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-002-0918-9

    authors: Iwanaka T,Arai M,Yamamoto H,Fukuzawa M,Kubota A,Kouchi K,Nio M,Satomi A,Sasaki F,Yoneda A,Ohhama Y,Takehara H,Morikawa Y,Miyano T

    更新日期:2003-05-01 00:00:00

  • The influence of gastroschisis on plasmatic coagulation, humoral immunity, and C-reactive protein.

    abstract::Around the 30th week of gestation, patients with gastroschisis (GS) develop chronic inflammatory reactions on the serosal surface of the eventrated loops of intestine that lead to severe hyperfibrinogenemia and hypercoagulability, particularly if they are born prematurely. This result was found on comparison of coagul...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/BF00183729

    authors: Limbach HG,Quinten A,Jesberger HJ,Karadiakkos N,Lipfert S

    更新日期:1996-03-01 00:00:00

  • Rare cause of a neck mass: successful balloon embolisation of a congenital external carotid artery-internal jugular vein fistula.

    abstract::Congenital arteriovenous fistulas are a rare cause of neck mass in children, but should be considered in the differential diagnosis of paediatric patients presenting with pulsatile neck masses even when there is no history of trauma. Balloon embolisation is the treatment of choice because of the high risk of surgical ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-011-2918-0

    authors: Ahmad S,Suleman FE

    更新日期:2011-12-01 00:00:00

  • In prenatally diagnosed CPAM, does the affected lobe influence the timing of symptom onset?

    abstract:PURPOSE:We investigated the relationship between the affected lobe and symptom onset in prenatally diagnosed congenital pulmonary airway malformation (CPAM). METHODS:53 CPAM patients diagnosed prenatally were reviewed retrospectively by creating 2 groups according to symptom onset. Group Sneo: (symptomatic during the ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-019-04460-x

    authors: Sueyoshi R,Shibuya S,Ochi T,Okawada M,Miyano G,Koga H,Lane GJ,Yamataka A

    更新日期:2019-05-01 00:00:00

  • Outcome of submucosal injection of different sclerosing materials for rectal prolapse in children.

    abstract::Parasitic infestations, mainly enterobiasis and amoebiasis, and poor toilet training practices are commonly associated with rectal prolapse in developing countries. Injection sclerotherapy is one of the commonly used modalities for treating partial rectal prolapse in children. Various materials are available for such ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-004-1197-4

    authors: Fahmy MA,Ezzelarab S

    更新日期:2004-05-01 00:00:00

  • Multiple trauma in pediatric patients.

    abstract::We analyzed the causes and diagnoses, the treatment, short and long-term outcome of a consecutive series of 70 pediatric polytrauma patients. From 1989 to 1996, 70 children (aged 10 months to 16 years, mean 7.4 years) presented with multiple trauma. A follow-up investigation was performed 4.2 years (mean) after the ac...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-003-0954-0

    authors: Schalamon J,v Bismarck S,Schober PH,Höllwarth ME

    更新日期:2003-08-01 00:00:00