Sampling strategies in nested case-control studies.

abstract：:Isolated rat and human hepatocytes in primary culture were shown to metabolize AAF to reactive intermediates which damaged hepatocyte DNA. A significant increase in unscheduled DNA synthesis was detectable by autoradiography in rat and human hepatocytes exposed to concentrations of AAF as low as 1 microM. When rat hep...

journal_title：Environmental health perspectives

authors： Strom SC,Jirtle RL,Michalopoulos G

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND:After Hurricane Katrina, many New Orleans homes remained flooded for weeks, promoting heavy microbial growth. OBJECTIVES:A small demonstration project was conducted November 2005-January 2006 aiming to recommend safe remediation techniques and safe levels of worker protection, and to characterize airborne m...

journal_title：Environmental health perspectives

authors： Chew GL,Wilson J,Rabito FA,Grimsley F,Iqbal S,Reponen T,Muilenberg ML,Thorne PS,Dearborn DG,Morley RL

更新日期：2006-12-01 00:00:00

abstract：:We examined the estrogenicity of binary mixtures of the hydroxylated polychlorinated biphenyls (OHPCBs) 2,4,6-trichloro-4'-biphenylol (2,4,6-TCB-4'-OH) and 2,3,4,5-tetrachloro-4'-biphenylol and the pesticides endosulfan and dieldrin. The OHPCBs and pesticides were tested in both the MCF-7 focus assay and a competitive...

journal_title：Environmental health perspectives

authors： Arcaro KF,Vakharia DD,Yang Y,Gierthy JF

更新日期：1998-08-01 00:00:00

abstract：:In this study we examined the impact of weather variability and tides on the transmission of Barmah Forest virus (BFV) disease and developed a weather-based forecasting model for BFV disease in the Gladstone region, Australia. We used seasonal autoregressive integrated moving-average (SARIMA) models to determine the c...

journal_title：Environmental health perspectives

authors： Naish S,Hu W,Nicholls N,Mackenzie JS,McMichael AJ,Dale P,Tong S

更新日期：2006-05-01 00:00:00

abstract：:Two remote maritime populations were evaluated for their biological exposure to organochlorines in 1989-1990. Because of their high intake of seafood, these two populations have high biological levels. One hundred nine breast milk samples from Inuit women from Arctic Québec were analyzed to determine levels of polychl...

journal_title：Environmental health perspectives

authors： Dewailly E,Ryan JJ,Laliberté C,Bruneau S,Weber JP,Gingras S,Carrier G

更新日期：1994-01-01 00:00:00

abstract：:The problems of quantitating chrysotile in water by fiber count techniques are reviewed briefly and the use of mass quantitation is suggested as a preferable measure. Chrysotile fiber has been found in almost every sample of natural water examined, but generally transmission electron miscroscopy (TEM) is required beca...

journal_title：Environmental health perspectives

authors： Speil S

更新日期：1974-12-01 00:00:00

abstract：BACKGROUND:There is a need to identify and evaluate an effective mitigation program for arsenic exposure from drinking water in Bangladesh. OBJECTIVE:We evaluated the effectiveness of a multifaceted mitigation program to reduce As exposure among 11,746 individuals in a prospective cohort study initiated in 2000 in Ara...

journal_title：Environmental health perspectives

authors： Chen Y,van Geen A,Graziano JH,Pfaff A,Madajewicz M,Parvez F,Hussain AZ,Slavkovich V,Islam T,Ahsan H

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Arsenic (As) occurs as monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) in humans, and the methylation pattern demonstrates large interindividual differences. The fraction of urinary MMA is a marker for susceptibility to As-related diseases. OBJECTIVES:We evaluated the impact of polymorphisms in ...

journal_title：Environmental health perspectives

authors： Engström K,Vahter M,Mlakar SJ,Concha G,Nermell B,Raqib R,Cardozo A,Broberg K

更新日期：2011-02-01 00:00:00

abstract：:The hexavalent oxidation state of chromium [Cr(VI)] is a well-established human carcinogen, although the mechanism of cancer induction is currently unknown. Intracellular reduction of Cr(VI) forms Cr(V), which is thought to play a fundamental role in the mechanism of DNA damage by this carcinogen. Two separate pathway...

journal_title：Environmental health perspectives

authors： Sugden KD,Martin BD

更新日期：2002-10-01 00:00:00

abstract：:Several organophosphate and organochlorine compounds, including pesticides commonly found in the Great Lakes basin, have the potential to induce immunotoxicity. Because of biomagnification and accumulation in the food chain, Great Lakes residents may inadvertently be exposed to these compounds and thus face increased ...

journal_title：Environmental health perspectives

authors： Thomas PT

更新日期：1995-12-01 00:00:00

abstract：:Polychlorinated biphenyls (PCBs) and dioxins are known as neurotoxic compounds that may modulate sex steroid hormones. Steroid hormones play a mediating role in brain development and may influence behaviors that show sex differences, such as childhood play behavior. In this study we evaluated the effects of perinatal ...

journal_title：Environmental health perspectives

authors： Vreugdenhil HJ,Slijper FM,Mulder PG,Weisglas-Kuperus N

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Experimental tools for studying the complex steroidogenic interactions that occur between placenta and fetus during human pregnancy are extremely limited. OBJECTIVES:We aimed to develop a co-culture model to study steroidogenesis by the human fetoplacental unit and its disruption by exposure to environmenta...

journal_title：Environmental health perspectives

authors： Hudon Thibeault AA,Deroy K,Vaillancourt C,Sanderson JT

更新日期：2014-04-01 00:00:00

abstract：:Children may be more susceptible to exposures to environmental toxins than adults and may be more vulnerable to their effects. Because of this, the health care community and those responsible for children need to be alert to possible environmental factors in identifying and responding to the health problems of childre...

journal_title：Environmental health perspectives

authors： Goldman LR

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Previous literature suggests that higher ambient temperature may play a role in increasing the risk of suicide. However, no multi-country study has explored the shape of the association and the role of moderate and extreme heat across different locations. OBJECTIVES:We examined the short-term temperature-su...

journal_title：Environmental health perspectives

authors： Kim Y,Kim H,Gasparrini A,Armstrong B,Honda Y,Chung Y,Ng CFS,Tobias A,Íñiguez C,Lavigne E,Sera F,Vicedo-Cabrera AM,Ragettli MS,Scovronick N,Acquaotta F,Chen BY,Guo YL,Seposo X,Dang TN,de Sousa Zanotti Stagliorio Coel

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Despite evidence of atrazine toxicity in developing organisms from experimental studies, few studies--and fewer epidemiologic investigations--have examined the potential effects of prenatal exposure. OBJECTIVES:We assessed the association between adverse birth outcomes and urinary biomarkers of prenatal atr...

journal_title：Environmental health perspectives

authors： Chevrier C,Limon G,Monfort C,Rouget F,Garlantézec R,Petit C,Durand G,Cordier S

更新日期：2011-07-01 00:00:00

abstract：:The lead exposure of children and their mothers has been studied in two towns with mean soil lead contents of 900 and 400 ppm. No significant difference in blood or fecal lead contents was demonstrated between the two populations, but a small difference in hair lead content was shown. The blood lead content of childre...

journal_title：Environmental health perspectives

authors： Barltrop D,Strehlow CD,Thorton I,Webb JS

更新日期：1974-05-01 00:00:00

abstract：:Over 250 adults and children were exposed to chlordane when the wooden building surfaces and soil around an apartment complex were sprayed in 1987. Two hundred-sixteen adults had neurobehavioral functions measured and completed questionnaires for symptom frequency, mood status, confounding factors, and medical, rheuma...

journal_title：Environmental health perspectives

authors： Kilburn KH,Thornton JC

更新日期：1995-07-01 00:00:00

abstract：:The disruption of the reproductive system of male and female animals in the wild has been attributed to environmental chemicals (xenobiotics). The effects seen mirror alterations one might anticipate if the steroid hormone-dependent processes that regulate these systems were impaired. To determine whether xenobiotics ...

journal_title：Environmental health perspectives

authors： Danzo BJ

更新日期：1997-03-01 00:00:00

abstract：:We measured tumor-associated proteins (TAPs) and pollutants in blood, serum, and urine of 200 nonsmoking women 50-65 years of age, residing in the rural municipality of Peer or in Hoboken or Wilrijk, industrial suburbs of Antwerp, Belgium. Persons with occupational exposures or commuting to other towns were excluded. ...

journal_title：Environmental health perspectives

authors： van Larebeke NA,Bracke ME,Nelen V,Koppen G,Schoeters G,Van Loon H,Vlietinck R

更新日期：2006-06-01 00:00:00

abstract：:A microscopic, ultrastructural, and morphometric study was made of the gills of tench (Tinca tinca, L.) subjected to acute experimental lead nitrate poisoning. Twenty-one adult tench were subjected to poisoning and a further 22 were used as controls. Lesions were characterized by the appearance of edema and epithelial...

journal_title：Environmental health perspectives

authors： Roncero V,Vincente JA,Redondo E,Gãzquez A,Duran E

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Tremor is one of the most common neurological signs, yet its etiology is poorly understood. Case-control studies suggest an association between blood lead and essential tremor, and that this association is modified by polymorphisms in the δ-aminolevulinic acid dehydrogenase (ALAD) gene. OBJECTIVE:We aimed t...

journal_title：Environmental health perspectives

authors： Ji JS,Power MC,Sparrow D,Spiro A 3rd,Hu H,Louis ED,Weisskopf MG

更新日期：2015-05-01 00:00:00

abstract：:The 26th annual conference of the International Society for Environmental Epidemiology was held 24-28 August 2014 in Seattle, Washington. The conference theme was "From Local to Global: Advancing Science for Policy in Environmental Health." Sessions highlighted results assessing the burden of diseases from environment...

journal_title：Environmental health perspectives

authors：

更新日期：2014-10-30 00:00:00

abstract：:As a result of the Leadership Conference on Biomedical Research and the Environment, the Facilities Committee focused its work on the development of best environmental practices at biomedical research facilities at the university and independent research facility level as well as consideration of potential involvement...

journal_title：Environmental health perspectives

authors： Medlin EL,Grupenhoff JT

更新日期：2000-12-01 00:00:00

abstract：:Chromate is an established human carcinogen. There have been many studies of the reactivity of chromate aimed at improving understanding of chromate toxicity. In the present paper a number of conclusions of these studies are reviewed and considered in the light of new results obtained in our laboratories. A number of ...

journal_title：Environmental health perspectives

authors： O'Brien P,Kortenkamp A

更新日期：1994-09-01 00:00:00

abstract：:Previous NIOSH studies demonstrated the embryo- and fetotoxicity and teratogenicity of ethylene glycol monoethyl ether (EGEE) applied to the shaved skin of pregnant rats. In the present study ethylene glycol monoethyl ether acetate (EGEEA), ethylene glycol monobutyl ether (EGBE), and diethylene glycol monoethyl ether ...

journal_title：Environmental health perspectives

authors： Hardin BD,Goad PT,Burg JR

更新日期：1984-08-01 00:00:00

abstract：:The many anatomical, physiological, and biochemical differences among various mammalian species make it difficult to extrapolate carcinogenic potency data from animals to humans. The process is further complicated by the multistep origin of most malignant tumors in animals and humans due to the interaction of target c...

journal_title：Environmental health perspectives

authors： Slaga TJ

更新日期：1988-04-01 00:00:00

abstract：:Children are uniquely vulnerable to toxic chemicals in the environment. Among the environmental toxicants to which children are at risk of exposure are endocrine disruptors (EDs)--chemicals that have the capacity to interfere with hormonal signaling systems. EDs may alter feedback loops in the brain, pituitary, gonads...

journal_title：Environmental health perspectives

authors： Landrigan P,Garg A,Droller DB

更新日期：2003-10-01 00:00:00

abstract：:Concentrations of polychlorinated biphenyls (PCBs), hydroxylated metabolites of PCBs (HO-PCBs) and octachlorostyrene (4-HO-HpCS), and pentachlorophenol (PCP) were determined in umbilical cord plasma samples from three different regions of Québec. The regions studied included two coastal areas where exposure to PCBs is...

journal_title：Environmental health perspectives

authors： Sandau CD,Ayotte P,Dewailly E,Duffe J,Norstrom RJ

更新日期：2002-04-01 00:00:00

abstract：:The subchronic inhalation toxicology of ethylene glycol monoethyl ether (EGEE) was evaluated in rats and rabbits using a 13-week exposure regimen. Groups of 20 rabbits (10 M, 10 F) and 30 rats (15 M, 15 F) were exposed to a vapor of 25 ppm, 100 ppm, or 400 ppm, 6 hr/day, 5 days/week. The control groups received air on...

journal_title：Environmental health perspectives

authors： Barbee SJ,Terrill JB,DeSousa DJ,Conaway CC

更新日期：1984-08-01 00:00:00

abstract：:The extracellular lining of the lungs is reviewed. The pulmonary extracellular lining is a complex mixture of phospholipids, proteins and carbohydrates which is absolutely essential for the maintenance of normal pulmonary functions such as gas exchange. Without the lining the lungs would collapse. Alterations in the p...

journal_title：Environmental health perspectives

authors： George G,Hook GE

更新日期：1984-04-01 00:00:00