Mold and endotoxin levels in the aftermath of Hurricane Katrina: a pilot project of homes in New Orleans undergoing renovation.

Abstract:

BACKGROUND:After Hurricane Katrina, many New Orleans homes remained flooded for weeks, promoting heavy microbial growth. OBJECTIVES:A small demonstration project was conducted November 2005-January 2006 aiming to recommend safe remediation techniques and safe levels of worker protection, and to characterize airborne mold and endotoxin throughout cleanup. METHODS:Three houses with floodwater lines between 0.3 and 2 m underwent intervention, including disposal of damaged furnishings and drywall, cleaning surfaces, drying remaining structure, and treatment with a biostatic agent. We measured indoor and outdoor bioaerosols before, during, and after intervention. Samples were analyzed for fungi [culture, spore analysis, polymerase chain reaction (PCR)] and endotoxin. In one house, realtime particle counts were also assessed, and respirator-efficiency testing was performed to establish workplace protection factors (WPF). RESULTS:At baseline, culturable mold ranged from 22,000 to 515,000 colony-forming units/m3, spore counts ranged from 82,000 to 630,000 spores/m3, and endotoxin ranged from 17 to 139 endotoxin units/m3. Culture, spore analysis, and PCR indicated that Penicillium, Aspergillus, and Paecilomyces predominated. After intervention, levels of mold and endotoxin were generally lower (sometimes, orders of magnitude). The average WPF against fungal spores for elastomeric respirators was higher than for the N95 respirators. CONCLUSIONS:During baseline and intervention, mold and endotoxin levels were similar to those found in agricultural environments. We strongly recommend that those entering, cleaning, and repairing flood-damaged homes wear respirators at least as protective as elastomeric respirators. Recommendations based on this demonstration will benefit those involved in the current cleanup activities and will inform efforts to respond to future disasters.

authors

Chew GL,Wilson J,Rabito FA,Grimsley F,Iqbal S,Reponen T,Muilenberg ML,Thorne PS,Dearborn DG,Morley RL

doi

10.1289/ehp.9258

subject

Has Abstract

pub_date

2006-12-01 00:00:00

pages

1883-9

issue

12

eissn

0091-6765

issn

1552-9924

journal_volume

114

pub_type

杂志文章
  • Relation between cord blood mercury levels and early child development in a World Trade Center cohort.

    abstract:OBJECTIVE:This study was designed to determine whether prenatal mercury exposure, including potential releases from the World Trade Center (WTC) disaster, adversely affects fetal growth and child development. METHODS:We determined maternal and umbilical cord blood total mercury of nonsmoking women who delivered at ter...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.10831

    authors: Lederman SA,Jones RL,Caldwell KL,Rauh V,Sheets SE,Tang D,Viswanathan S,Becker M,Stein JL,Wang RY,Perera FP

    更新日期:2008-08-01 00:00:00

  • Asthma symptoms in Hispanic children and daily ambient exposures to toxic and criteria air pollutants.

    abstract::Although acute adverse effects on asthma have been frequently found for the U.S. Environmental Protection Agency's principal criteria air pollutants, there is little epidemiologic information on specific hydrocarbons from toxic emission sources. We conducted a panel study of 22 Hispanic children with asthma who were 1...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.5992

    authors: Delfino RJ,Gong H Jr,Linn WS,Pellizzari ED,Hu Y

    更新日期:2003-04-01 00:00:00

  • An experimental approach to the evaluation of the biopersistence of respirable synthetic fibers and minerals.

    abstract::The biopersistence of fibers and minerals in the respiratory tract is an important parameter in the toxicity of those materials. The biopersistence of respirable synthetic fibers and minerals in man can be most closely evaluated in an animal model. While acellular and in vitro systems are important for initial evaluat...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.94102s515

    authors: Bernstein DM,Mast R,Anderson R,Hesterberg TW,Musselman R,Kamstrup O,Hadley J

    更新日期:1994-10-01 00:00:00

  • Do the health benefits of cycling outweigh the risks?

    abstract:BACKGROUND:Although from a societal point of view a modal shift from car to bicycle may have beneficial health effects due to decreased air pollution emissions, decreased greenhouse gas emissions, and increased levels of physical activity, shifts in individual adverse health effects such as higher exposure to air pollu...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.0901747

    authors: Johan de Hartog J,Boogaard H,Nijland H,Hoek G

    更新日期:2010-08-01 00:00:00

  • 13th Meeting of the Scientific Group on Methodologies for the Safety Evaluation of Chemicals (SGOMSEC): alternative testing methodologies for ecotoxicity.

    abstract::There is growing public pressure to minimize the use of vertebrates in ecotoxicity testing; therefore, effective alternatives to toxicity tests causing suffering are being sought. This report discusses alternatives and differs in some respects from the reports of the other three groups because the primary concern is w...

    journal_title:Environmental health perspectives

    pub_type:

    doi:10.1289/ehp.98106441

    authors: Walker C,Kaiser K,Klein W,Lagadic L,Peakall D,Sheffield S,Soldan T,Yasuno M

    更新日期:1998-04-01 00:00:00

  • Three decades of silicosis: disease trends at autopsy in South African gold miners.

    abstract:BACKGROUND:Eliminating silicosis is a priority of the International Labour Organization and the World Health Organization. Prevalence is particularly high in developing countries. OBJECTIVES:We describe trends in silicosis among South African gold miners who had had an autopsy between 1975 and 2007 and quantify the co...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.0900918

    authors: Nelson G,Girdler-Brown B,Ndlovu N,Murray J

    更新日期:2010-03-01 00:00:00

  • Interaction of alkylmercuric compounds with sodium selenite. I. Metabolism of ethylmercuric chloride administered alone and in combination with sodium selenite in rats.

    abstract::The effect of sodium selenite administered intragastrically in repeated doses to rats receiving ethylmercuric chloride po in various repeated doses (0.25 or 2.5 mg Hg/kg) on the excretion, whole-body retention, and organ distribution of mercury was studied. Selenium was found to affect the distribution of ethylmercury...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.39-1568742

    authors: Brzeźnicka EA,Chmielnicka J

    更新日期:1981-06-01 00:00:00

  • Are current or future mesothelioma epidemics in Hong Kong the tragic legacy of uncontrolled use of asbestos in the past?

    abstract::Inhaled asbestos fibers may contribute to three-fourths of malignant mesotheliomas diagnosed in men and almost 40% of cases diagnosed in women. Bans on the manufacture and sale of amphibole asbestos fibers are expected to reduce the incidence of mesothelioma, but the long latency period from initial exposure to clinic...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.0900868

    authors: Tse LA,Yu IT,Goggins W,Clements M,Wang XR,Au JS,Yu KS

    更新日期:2010-03-01 00:00:00

  • Dietary intake and its contribution to longitudinal organophosphorus pesticide exposure in urban/suburban children.

    abstract:BACKGROUND:The widespread use of organophosphorus (OP) pesticides has led to frequent exposure in adults and children. Because such exposure may cause adverse health effects, particularly in children, the sources and patterns of exposure need to be studied further. OBJECTIVES:We assessed young urban/suburban children'...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.10912

    authors: Lu C,Barr DB,Pearson MA,Waller LA

    更新日期:2008-04-01 00:00:00

  • Cell cycle controls: potential targets for chemical carcinogens?

    abstract::The progression of the cell cycle is controlled by the action of both positive and negative growth regulators. The key players in this activity include a family of cyclins and cyclin-dependent kinases, which are themselves regulated by other kinases and phosphatases. Maintenance of balanced cell cycle controls may be ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.93101s59

    authors: Afshari CA,Barrett JC

    更新日期:1993-12-01 00:00:00

  • Associations between Environmental Quality and Mortality in the Contiguous United States, 2000-2005.

    abstract:BACKGROUND:Assessing cumulative effects of the multiple environmental factors influencing mortality remains a challenging task. OBJECTIVES:This study aimed to examine the associations between cumulative environmental quality and all-cause and leading cause-specific (heart disease, cancer, and stroke) mortality rates. ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP119

    authors: Jian Y,Messer LC,Jagai JS,Rappazzo KM,Gray CL,Grabich SC,Lobdell DT

    更新日期:2017-03-01 00:00:00

  • A unique co-culture model for fundamental and applied studies of human fetoplacental steroidogenesis and interference by environmental chemicals.

    abstract:BACKGROUND:Experimental tools for studying the complex steroidogenic interactions that occur between placenta and fetus during human pregnancy are extremely limited. OBJECTIVES:We aimed to develop a co-culture model to study steroidogenesis by the human fetoplacental unit and its disruption by exposure to environmenta...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.1307518

    authors: Hudon Thibeault AA,Deroy K,Vaillancourt C,Sanderson JT

    更新日期:2014-04-01 00:00:00

  • Chemical plants remain vulnerable to terrorists: a call to action.

    abstract::U.S. chemical plants currently have potentially catastrophic vulnerabilities as terrorist targets. The possible consequences of these vulnerabilities echo from the tragedies of the Bhopal incident in 1984 to the terrorist attacks on 11 September 2001 and, most recently, Hurricanes Katrina and Rita. Findings from a 200...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.8762

    authors: Lippin TM,McQuiston TH,Bradley-Bull K,Burns-Johnson T,Cook L,Gill ML,Howard D,Seymour TA,Stephens D,Williams BK

    更新日期:2006-09-01 00:00:00

  • Sources of mercury exposure for U.S. seafood consumers: implications for policy.

    abstract:BACKGROUND:Recent policies attempting to reduce adverse effects of methylmercury exposure from fish consumption in the United States have targeted reductions in anthropogenic emissions from U.S. sources. OBJECTIVES:To analyze the prospects for future North American and international emissions controls, we assessed the...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.0900811

    authors: Selin NE,Sunderland EM,Knightes CD,Mason RP

    更新日期:2010-01-01 00:00:00

  • Modulation of eicosanoid production by human alveolar macrophages exposed to silica in vitro.

    abstract::Repeated inhalation of silica dust can lead to inflammation and fibrosis in human lung and in experimental animal models. The alveolar macrophage is believed to play a pivotal role in this process. Numerous macrophage-derived growth factors, cytokines, and arachidonic acid metabolites have been shown to contribute to ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.929777

    authors: Koren HS,Joyce M,Devlin RB,Becker S,Driscoll K,Madden MC

    更新日期:1992-07-01 00:00:00

  • Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents.

    abstract::Of 240 pesticides screened for carcinogenicity by the U.S. Environmental Protection Agency Office of Pesticide Programs, at least 24 (10%) produce thyroid follicular cell tumors in rodents. Thirteen of the thyroid carcinogens also induce liver tumors, mainly in mice, and 9 chemicals produce tumors at other sites. Some...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.98106437

    authors: Hurley PM

    更新日期:1998-08-01 00:00:00

  • Health effects of electric and magnetic fields: overview of research recommendations.

    abstract::We developed a series of articles concerning epidemiologic research on potential health effects of electric and magnetic fields. Our goal was to identify methodological issues that have arisen through past studies of cancer, reproduction, and neurobehavioral outcomes in order to suggest strategies to extend knowledge....

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.93101s471

    authors: Savitz DA

    更新日期:1993-12-01 00:00:00

  • Skin permeation and cutaneous hypersensitivity as a basis for making risk assessments of chromium as a soil contaminant.

    abstract::A literature review of experimental and human exposure studies of skin permeation and cutaneous hypersensitivity reactions evoked by chromium was carried out to provide a basis for making a risk assessment of chromium as a soil contaminant. In vitro and in vivo studies demonstrated that 1 to 4% of the applied dose of ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.92-1519389

    authors: Bagdon RE,Hazen RE

    更新日期:1991-05-01 00:00:00

  • Strategies for setting occupational exposure limits for particles.

    abstract::To set occupational exposure limits (OELs) for aerosol particles, dusts, or chemicals, one has to evaluate whether mechanistic considerations permit identification of a no observed effect level (NOEL). In the case of carcinogenic effects, this can be assumed if no genotoxicity is involved, and exposure is considered s...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.97105s51357

    authors: Greim HA,Ziegler-Skylakakis K

    更新日期:1997-09-01 00:00:00

  • Cancer incidence in world trade center rescue and recovery workers, 2001-2008.

    abstract:BACKGROUND:World Trade Center (WTC) rescue and recovery workers were exposed to a complex mix of pollutants and carcinogens. OBJECTIVE:The purpose of this investigation was to evaluate cancer incidence in responders during the first 7 years after 11 September 2001. METHODS:Cancers among 20,984 consented participants ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.1205894

    authors: Solan S,Wallenstein S,Shapiro M,Teitelbaum SL,Stevenson L,Kochman A,Kaplan J,Dellenbaugh C,Kahn A,Biro FN,Crane M,Crowley L,Gabrilove J,Gonsalves L,Harrison D,Herbert R,Luft B,Markowitz SB,Moline J,Niu X,Sacks H,

    更新日期:2013-06-01 00:00:00

  • Bisphenol A and Dental Sealants: Olea's Response.

    abstract::Comments on "Determination of bisphenol A and related aromatic compounds released from Bis-GMA-based composites and sealants by high performance liquid chromatography." by ulgar R, Olea-Serrano MF, Novillo-Fertrell A, Rivas A, Pazos P, Pedraza V, Navajas J-M, Olea N. Environ Health Perspect 108:21-27 (2000). ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.108-a546a

    authors: Olea N

    更新日期:2000-12-01 00:00:00

  • Impatiens pollen germination and tube growth as a bioassay for toxic substances.

    abstract::Pollen of Impatiens sultanii Hook F. germinates and forms tubes rapidly at 25 degrees C in a simple medium containing 111.0 ppm CaCl2, 13.6 ppm KH2PO4, and 1000 ppm boric acid. Calcium, potassium, and boron are essential for germination and tube growth, but sucrose is not required. Pollen tubes grow with equal rapidit...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.813795

    authors: Bilderback DE

    更新日期:1981-01-01 00:00:00

  • Associations between Blood and Urine Arsenic Concentrations and Global Levels of Post-Translational Histone Modifications in Bangladeshi Men and Women.

    abstract:BACKGROUND:Exposure to inorganic arsenic is associated with numerous adverse health outcomes, with susceptibility differing by sex. Although evidence from in vitro studies suggests that arsenic alters post-translational histone modifications (PTHMs), evidence in humans is limited. OBJECTIVES:The objectives were to det...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.1510412

    authors: Howe CG,Liu X,Hall MN,Slavkovich V,Ilievski V,Parvez F,Siddique AB,Shahriar H,Uddin MN,Islam T,Graziano JH,Costa M,Gamble MV

    更新日期:2016-08-01 00:00:00

  • Interactions between glutathione S-transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease.

    abstract:BACKGROUND:Air pollutants may induce airway inflammation and sensitization due to generation of reactive oxygen species. The genetic background to these mechanisms could be important effect modifiers. OBJECTIVE:Our goal was to assess interactions between exposure to air pollution and single nucleotide polymorphisms (S...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.11117

    authors: Melén E,Nyberg F,Lindgren CM,Berglind N,Zucchelli M,Nordling E,Hallberg J,Svartengren M,Morgenstern R,Kere J,Bellander T,Wickman M,Pershagen G

    更新日期:2008-08-01 00:00:00

  • Renal and neurologic effects of cadmium, lead, mercury, and arsenic in children: evidence of early effects and multiple interactions at environmental exposure levels.

    abstract::Lead, cadmium, mercury, and arsenic are common environmental pollutants in industrialized countries, but their combined impact on children's health is little known. We studied their effects on two main targets, the renal and dopaminergic systems, in > 800 children during a cross-sectional European survey. Control and ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.8202

    authors: de Burbure C,Buchet JP,Leroyer A,Nisse C,Haguenoer JM,Mutti A,Smerhovsky Z,Cikrt M,Trzcinka-Ochocka M,Razniewska G,Jakubowski M,Bernard A

    更新日期:2006-04-01 00:00:00

  • The effect of fine and coarse particulate air pollution on mortality: a national analysis.

    abstract:BACKGROUND:Although many studies have examined the effects of air pollution on mortality, data limitations have resulted in fewer studies of both particulate matter with an aerodynamic diameter of 2.5 and < 10 mi...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.0800108

    authors: Zanobetti A,Schwartz J

    更新日期:2009-06-01 00:00:00

  • UV-B exposure impairs resistance to infection by Trichinella spiralis.

    abstract::To assess the possibility that increases in UV-B exposure on the earth's surface could lead to impaired resistance to several infectious diseases, we studied the effect of UV-B exposure on resistance against Trichinella spiralis. Wistar rats, orally infected with T. spiralis larvae, were exposed to suberythemal doses ...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/ehp.94102298

    authors: Goettsch W,Garssen J,Deijns A,de Gruijl FR,van Loveren H

    更新日期:1994-03-01 00:00:00

  • Effects of Inorganic Arsenic, Methylated Arsenicals, and Arsenobetaine on Atherosclerosis in the Mouse Model and the Role of As3mt-Mediated Methylation.

    abstract:BACKGROUND:Arsenic is metabolized through a series of oxidative methylation reactions by arsenic (3) methyltransferase (As3MT) to yield methylated intermediates. Although arsenic exposure is known to increase the risk of atherosclerosis, the contribution of arsenic methylation and As3MT remains undefined. OBJECTIVES:O...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章

    doi:10.1289/EHP806

    authors: Negro Silva LF,Lemaire M,Lemarié CA,Plourde D,Bolt AM,Chiavatti C,Bohle DS,Slavkovich V,Graziano JH,Lehoux S,Mann KK

    更新日期:2017-07-05 00:00:00

  • Role of proto-oncogene activation in carcinogenesis.

    abstract::The accumulation of genetic damage in the forms of activated proto-oncogenes and inactivated tumor-suppressor genes is the driving force in the evolution of a normal cell to a malignant cell. For example, both the activation of ras oncogenes and the inactivation of several suppressor genes, including p53, have been ob...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.929813

    authors: Anderson MW,Reynolds SH,You M,Maronpot RM

    更新日期:1992-11-01 00:00:00

  • Chromosomal methods in population studies.

    abstract::A brief description of chromosome aberrations and sister chromatid exchange (SCE) as cytogenetic endpoints for evaluation of DNA damaging agents is presented. Problems associated with the use of cytogenetic assays as population monitors of radiation and chemical exposures are discussed. Adequate cell sample size requi...

    journal_title:Environmental health perspectives

    pub_type: 杂志文章,评审

    doi:10.1289/ehp.8142107

    authors: Conner MK,Wald N

    更新日期:1981-12-01 00:00:00