Chemical models important in understanding the ways in which chromate can damage DNA.

abstract：BACKGROUND:Although from a societal point of view a modal shift from car to bicycle may have beneficial health effects due to decreased air pollution emissions, decreased greenhouse gas emissions, and increased levels of physical activity, shifts in individual adverse health effects such as higher exposure to air pollu...

journal_title：Environmental health perspectives

authors： Johan de Hartog J,Boogaard H,Nijland H,Hoek G

更新日期：2010-08-01 00:00:00

abstract：:Man-made endocrine-disrupting chemicals (EDCs) present a threat to biodiversity, even in remote areas. To date, numerous wildlife species have been affected by EDCs in the environment, but it is likely that many more species are suffering effects that have not yet been reported. Impaired reproduction, damaged brain fu...

journal_title：Environmental health perspectives

authors： Lyons G

更新日期：2006-04-01 00:00:00

abstract：:The three modern "faces" of mercury are our perceptions of risk from the exposure of billions of people to methyl mercury in fish, mercury vapor from amalgam tooth fillings, and ethyl mercury in the form of thimerosal added as an antiseptic to widely used vaccines. In this article I review human exposure to and the to...

journal_title：Environmental health perspectives

authors： Clarkson TW

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:C60 fullerenes and single-walled carbon nanotubes (SWCNT) are projected to be used in medicine and consumer products with potential human exposure. The hazardous effects of these particles are expected to involve oxidative stress with generation of oxidatively damaged DNA that might be the initiating event i...

journal_title：Environmental health perspectives

authors： Folkmann JK,Risom L,Jacobsen NR,Wallin H,Loft S,Møller P

更新日期：2009-05-01 00:00:00

abstract：:Enhanced transport of trace metal in porous media can occur in the presence of a ligand or "carrier" that has a high affinity for binding the pollutant, is dispersed and mobile in the soil environment, is recalcitrant with respect to microbial degradation, and is acceptable to the public. These aspects of the facilita...

journal_title：Environmental health perspectives

authors： Chen JH,Czajka DR,Lion LW,Shuler ML,Ghiorse WC

更新日期：1995-02-01 00:00:00

abstract：:In recent years, it has become apparent that minerals can trigger alterations in gene expression by initiating signaling events upstream of gene transactivation. These cascades may be initiated at the cell surface after interaction of minerals with the plasma membrane either through receptorlike mechanisms or integrin...

journal_title：Environmental health perspectives

authors： Mossman BT,Faux S,Janssen Y,Jimenez LA,Timblin C,Zanella C,Goldberg J,Walsh E,Barchowsky A,Driscoll K

更新日期：1997-09-01 00:00:00

abstract：:Potential public health effects associated with exposure to metal emissions from hazardous waste incinerators through noninhalation pathways were evaluated. Instead of relying on modeling the movement of toxicants through various environmental media, an approach based on estimating changes from baseline levels of expo...

journal_title：Environmental health perspectives

authors： Sedman RM,Polisini JM,Esparza JR

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Developmental exposure to polychlorinated biphenyls (PCBs) or methylmercury (MeHg) can result in a variety of neurotoxic effects, including long-term auditory deficits. However, little is known about the effects of combined exposure to PCBs and MeHg on auditory function. OBJECTIVE:We developmentally exposed...

journal_title：Environmental health perspectives

authors： Powers BE,Poon E,Sable HJ,Schantz SL

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Cumulative lead exposure is associated with a widened pulse pressure (PP; the -difference between systolic and diastolic blood pressure), a marker of arterial stiffness and a predictor of cardiovascular disease. Polymorphisms in the hemochromatosis gene (HFE) have been shown to modify the impact of cumulativ...

journal_title：Environmental health perspectives

authors： Zhang A,Park SK,Wright RO,Weisskopf MG,Mukherjee B,Nie H,Sparrow D,Hu H

更新日期：2010-09-01 00:00:00

abstract：:Studies of structure-activity relationships and molecular mechanisms of action are fundamental to our understanding of the harmful effects of chemicals on the environment and their more direct effects on human health. It is important to identify factors that determine toxicological effects of foreign chemicals in biol...

journal_title：Environmental health perspectives

authors： McKinney JD

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Despite evidence of atrazine toxicity in developing organisms from experimental studies, few studies--and fewer epidemiologic investigations--have examined the potential effects of prenatal exposure. OBJECTIVES:We assessed the association between adverse birth outcomes and urinary biomarkers of prenatal atr...

journal_title：Environmental health perspectives

authors： Chevrier C,Limon G,Monfort C,Rouget F,Garlantézec R,Petit C,Durand G,Cordier S

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Animal and epidemiologic studies suggest that exposure to light at night (LAN) may disrupt circadian patterns and decrease nocturnal secretion of melatonin, which may disturb estrogen regulation, leading to increased breast cancer risk. OBJECTIVES:We examined the association between residential outdoor LAN ...

journal_title：Environmental health perspectives

authors： James P,Bertrand KA,Hart JE,Schernhammer ES,Tamimi RM,Laden F

更新日期：2017-08-17 00:00:00

abstract：:Atlantic coast estuaries recently have experienced fish kills and fish with lesions attributed to Pfiesteria piscicida and related dinoflagellates. Human health effects have been reported from laboratory exposure and from a 1997 Maryland fish kill. North Carolina has recorded Pfiesteria-related fish kill events over t...

journal_title：Environmental health perspectives

authors： Swinker M,Koltai D,Wilkins J,Hudnell K,Hall C,Darcey D,Robertson K,Schmechel D,Stopford W,Music S

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:The U.S. Environmental Protection Agency is working toward gaining a better understanding of the human health impacts of exposure to complex air pollutant mixtures and the key features that drive the toxicity of these mixtures, which can then be used for future scientific and risk assessments. DATA SOURCES:...

journal_title：Environmental health perspectives

authors： Johns DO,Stanek LW,Walker K,Benromdhane S,Hubbell B,Ross M,Devlin RB,Costa DL,Greenbaum DS

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Animal studies suggest that early-life lead exposure influences gene expression and production of proteins associated with Alzheimer's disease (AD). OBJECTIVES:We attempted to assess the relationship between early-life lead exposure and potential biomarkers for AD among young men and women. We also attempte...

journal_title：Environmental health perspectives

authors： Mazumdar M,Xia W,Hofmann O,Gregas M,Ho Sui S,Hide W,Yang T,Needleman HL,Bellinger DC

更新日期：2012-05-01 00:00:00

abstract：:It was considered that the fall in lung function seen after exposure to cotton dust may be attributable in part to the activity of arachidonic acid metabolites, such as leucotrienes as well as to the more established release of histamine by cotton dust. However, we found that cotton and barley dusts elicited poor rele...

journal_title：Environmental health perspectives

authors： Thomson TA,Edwards JH,Al-Zubaidy TS,Brown RC,Poole A,Nicholls PJ

更新日期：1986-04-01 00:00:00

abstract：:Airway mucus is a complex airway secretion whose primary function as part of the mucociliary transport mechanism is to to serve as renewable and transportable barrier against inhaled particulates and toxic agents. The rheologic properties necessary for this function are imparted by glycoproteins, or mucins. Some respi...

journal_title：Environmental health perspectives

authors： Samet JM,Cheng PW

更新日期：1994-06-01 00:00:00

abstract：:This article reviews the epidemiologic studies of the association of ischemic heart disease risk and environmental tobacco smoke (ETS) exposure from a spouse who smokes. Seventeen studies (nine cohort, eight case-control) comprising more than 485,000 lifelong nonsmokers and 7,345 coronary heart disease (CHD) events we...

journal_title：Environmental health perspectives

authors： Thun M,Henley J,Apicella L

更新日期：1999-12-01 00:00:00

abstract：:Lung burden analysis was performed on 126 autopsy cases of persons who died in New York City from 1966 through 1968. Of the 126 cases, 107 were probably non-occupationally exposed, judging by occupational history and asbestos body content of lung. Fifty-three of the 107 cases contained short chrysotile fibers/fibrils,...

journal_title：Environmental health perspectives

authors： Langer AM,Nolan RP

更新日期：1994-10-01 00:00:00

abstract：:The effect of sodium selenite administered intragastrically in repeated doses to rats receiving ethylmercuric chloride po in various repeated doses (0.25 or 2.5 mg Hg/kg) on the excretion, whole-body retention, and organ distribution of mercury was studied. Selenium was found to affect the distribution of ethylmercury...

journal_title：Environmental health perspectives

authors： Brzeźnicka EA,Chmielnicka J

更新日期：1981-06-01 00:00:00

abstract：:The current Good Manufacturing Practice (cGMP) and effluent emission (use and disposal) regulations of the U.S. Food and Drug Administration (FDA) and manufacturing effluent discharge and emission regulations of the U.S. Environmental Protection Agency (U.S. EPA) require contained manufacture, use, and disposal of pha...

journal_title：Environmental health perspectives

authors： Velagaleti R,Burns PK,Gill M,Prothro J

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Traffic-related air pollution is emerging as a risk factor for Alzheimer's disease (AD) and impaired brain development. Individual differences in vulnerability to air pollution may involve the ε4 allele of Apolipoprotein E (APOE) gene, the primary genetic risk factor for AD. OBJECTIVE:We analyzed whether th...

journal_title：Environmental health perspectives

authors： Alemany S,Vilor-Tejedor N,García-Esteban R,Bustamante M,Dadvand P,Esnaola M,Mortamais M,Forns J,van Drooge BL,Álvarez-Pedrerol M,Grimalt JO,Rivas I,Querol X,Pujol J,Sunyer J

更新日期：2018-08-02 00:00:00

abstract：:Comments on "Determination of bisphenol A and related aromatic compounds released from Bis-GMA-based composites and sealants by high performance liquid chromatography." by ulgar R, Olea-Serrano MF, Novillo-Fertrell A, Rivas A, Pazos P, Pedraza V, Navajas J-M, Olea N. Environ Health Perspect 108:21-27 (2000). ...

journal_title：Environmental health perspectives

authors： Olea N

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Reported associations between gestational tobacco exposure and autism spectrum disorders (ASDs) have been inconsistent. OBJECTIVE:We estimated the association between maternal smoking during pregnancy and ASDs among children 8 years of age. METHODS:This population-based case-cohort study included 633,989 c...

journal_title：Environmental health perspectives

authors： Kalkbrenner AE,Braun JM,Durkin MS,Maenner MJ,Cunniff C,Lee LC,Pettygrove S,Nicholas JS,Daniels JL

更新日期：2012-07-01 00:00:00

abstract：:The phenomenon of fiber-induced cytotoxicity to P388D1 macrophagelike cells has been demonstrated to parallel (thus far without exception) the probability that the fiber will induce a pleural sarcoma (mesothelioma) in rats. This startling parallel in both cases seems to be essentially independent of the chemical natur...

journal_title：Environmental health perspectives

authors： Lipkin LE

更新日期：1980-02-01 00:00:00

abstract：:Many mammals methylate trivalent inorganic arsenic in liver to species that are released into the bloodstream and excreted in urine and feces. This study addresses how methylated arsenicals pass through cell membranes. We have previously shown that aquaglyceroporin channels, including Escherichia coli GlpF, Saccharomy...

journal_title：Environmental health perspectives

authors： Liu Z,Styblo M,Rosen BP

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:The damaging effects of exposure to environmental toxicants differentially affect genetically distinct individuals, but the mechanisms contributing to these differences are poorly understood. Genetic variation affects the establishment of the gene regulatory landscape and thus gene expression, and we hypothe...

journal_title：Environmental health perspectives

authors： Chappell GA,Israel JW,Simon JM,Pott S,Safi A,Eklund K,Sexton KG,Bodnar W,Lieb JD,Crawford GE,Rusyn I,Furey TS

更新日期：2017-10-16 00:00:00

abstract：BACKGROUND:Particulate matter ≤ 2.5 μm in aerodynamic diameter (PM2.5) has been consistently associated with preterm birth (PTB) to varying degrees, but roles of PM2.5 species have been less studied. OBJECTIVE:We estimated risk differences (RD) of PTB (reported per 106 pregnancies) associated with change in ambient co...

journal_title：Environmental health perspectives

authors： Rappazzo KM,Daniels JL,Messer LC,Poole C,Lobdell DT

更新日期：2015-10-01 00:00:00

abstract：:The industrial accident that occurred in the town of Seveso, Italy, in 1976 exposed a large population to substantial amounts of relatively pure 2,3,7,8-tetrachlorodibenzo-p-dioxin. Extensive monitoring of soil levels and measurements of a limited number of human blood samples allowed classification of the exposed pop...

journal_title：Environmental health perspectives

authors： Bertazzi PA,Bernucci I,Brambilla G,Consonni D,Pesatori AC

更新日期：1998-04-01 00:00:00

abstract：:Recent increases have been reported in industrial countries for several sites of cancer. The causes of these increases remain unknown. Efforts should proceed to identify those occupational groups with increases in the same sites, as these may indicate relevant exposures. Two analyses were undertaken: trends in cancer ...

journal_title：Environmental health perspectives

authors： Davis DL,Blair A,Hoel DG

更新日期：1993-04-01 00:00:00