A probabilistic and individualized approach for predicting treatment gains: an extension and application to anxiety disordered youth.

Abstract:

:The objective of this study was to extend the probability of treatment benefit method by adding treatment condition as a stratifying variable, and illustrate this extension of the methodology using the Child and Adolescent Anxiety Multimodal Study data. The probability of treatment benefit method produces a simple and practical way to predict individualized treatment benefit based on pretreatment patient characteristics. Two pretreatment patient characteristics were selected in the production of the probability of treatment benefit charts: baseline anxiety severity, measured by the Pediatric Anxiety Rating Scale, and treatment condition (cognitive-behavioral therapy, sertraline, their combination, and placebo). We produced two charts as exemplars which provide individualized and probabilistic information for treatment response and outcome to treatments for child anxiety. We discuss the implications of the use of the probability of treatment benefit method, particularly with regard to patient-centered outcomes and individualized decision-making in psychology and psychiatry.

journal_name

Behav Ther

journal_title

Behavior therapy

authors

Beidas RS,Lindhiem O,Brodman DM,Swan A,Carper M,Cummings C,Kendall PC,Albano AM,Rynn M,Piacentini J,McCracken J,Compton SN,March J,Walkup J,Ginsburg G,Keeton CP,Birmaher B,Sakolsky D,Sherrill J

doi

10.1016/j.beth.2013.05.001

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

126-36

issue

1

eissn

0005-7894

issn

1878-1888

pii

S0005-7894(13)00048-8

journal_volume

45

pub_type

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