Abstract:
PURPOSE:To evaluate the effects of alterations in the volume of contrast material on liver enhancement. MATERIALS AND METHODS:Thirty patients underwent repeat computed tomographic (CT) examinations within 6 months, the first with either 100, 150, or 180 mL of nonionic contrast material (2 mL/sec). In the second, only volume was altered. Liver attenuation was measured before and after contrast material administration, and enhancement was calculated for each image. Comparisons were made only within the same patients. RESULTS:Mean liver enhancement was greater with 150 mL compared with 100 mL beyond 55 seconds after injection. Mean peak enhancement was greater by 21 HU with 150 mL; mean time to peak enhancement was longer by 14 seconds. Mean liver enhancement was greater with 180 mL compared with 150 mL at all intervals beyond 80 seconds. Mean peak enhancement was greater by 22 HU; mean time to peak liver enhancement was longer by 24 seconds. CONCLUSION:Alterations in contrast material volume have substantial impact on liver enhancement and potentially tumor conspicuity. The optimal window of time for liver imaging after contrast material injection varies with the volume administered.
journal_name
Radiologyjournal_title
Radiologyauthors
Chambers TP,Baron RL,Lush RMdoi
10.1148/radiology.193.2.7972770subject
Has Abstractpub_date
1994-11-01 00:00:00pages
513-7issue
2eissn
0033-8419issn
1527-1315journal_volume
193pub_type
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