Abstract:
:The records of 71 patients with adenoid cystic carcinoma of the salivary glands were reviewed to determine the dose response relationships for this aggressive tumor. Local control after treatment was determined for all patients and analyzed with respect to extent of surgery and dose of radiation. Of 70 patients who were available for evaluation of local control, 28 (40%) had a local recurrence and 42 (60%) did not. The highest control rates were found in patients who underwent both radiation therapy and surgery. Patients who received a dose equal to or greater than 6,000 rad (60 Gy) in addition to surgery had significantly higher local control rates than those who received less than 6,000 rad (60 Gy). Distant metastases developed in 50% of patients regardless of local control, with the following distribution: 39% lung, 19% bone, and 10% disseminated soft-tissue metastases. Lymph node involvement was rare. Implications for combined modality treatment are discussed.
journal_name
Radiologyjournal_title
Radiologyauthors
Simpson JR,Thawley SE,Matsuba HMdoi
10.1148/radiology.151.2.6324280subject
Has Abstractpub_date
1984-05-01 00:00:00pages
509-12issue
2eissn
0033-8419issn
1527-1315journal_volume
151pub_type
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