Abstract:
:Leukocytes incubated with Cu(II) showed a decrease in both glutathione reductase activity and reduced glutathione content. The glucose 6-phosphate dehydrogenase activity under the same conditions was not affected. Serum albumin added to mixtures prevented the loss of enzyme activity, whileD-penicillamine andL-histidine had little effect. Prior oxidation of the cell-reduced glutathione did not diminish the enzyme inhibitory action of Cu(II). The amount of regeneration of reduced glutathione in leukocytes previously treated with diamide to oxidize their reduced glutathione was a function of Cu(II) concentration in the media. No evidence was obtained that elevated serum ceruloplasmin levels in rabbits, nor incubation of leukocytes in vitro with ceruloplasmin, affect leukocyte glutathione reductase activity. It was proposed that the major mechanism by which copper affects glutathione metabolism in leukocytes is by inhibition of glutathione reductase.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Rafter GWdoi
10.1007/BF02783258subject
Has Abstractpub_date
1982-06-01 00:00:00pages
191-7issue
2-3eissn
0163-4984issn
1559-0720journal_volume
4pub_type
杂志文章abstract::The purpose of this 42-day study was to investigate the effects of dietary excess vanadium on spleen growth and lesions by determining morphological changes and cell cycle of spleen. Four hundred twenty 1-day-old avian broilers were divided into six groups and fed on a corn-soybean basal diet as control diet or the sa...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8938-0
更新日期:2011-11-01 00:00:00
abstract::The effect of increased selenium uptake on serum selenium in diabetic children was investigated during the first 9 yr of the Finnish nationwide selenium fertilization program, which started in 1984. Serum selenium concentrations were followed in 237 diabetic children (mean age 8.1 yr) and 214 controls from 1984 to 199...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02790138
更新日期:1995-01-01 00:00:00
abstract::Quercetin, a plant-derived flavonoid, is frequently used as an antioxidant for efficient anti-oxidative capacity. However, whether quercetin has protective effects on goat sperm and preimplantation embryos against Cd2+-induced oxidative injury is still unclear. So, we researched the influence of quercetin on goat sper...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1255-8
更新日期:2018-10-01 00:00:00
abstract::Soaking of a rat diet, high in both plant phytate and phytase, progressively degraded the phytate content with time of soaking. This dephytinization in turn enhanced the digestion of feed organic matter in the animals, and it significantly improved the absorption and retention of minerals and trace elements as observe...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783810
更新日期:1993-10-01 00:00:00
abstract::In this study, the induction of metallothionein (MT) in one species of oyster Ostrea edulis exposed to copper (Cu) and zinc (Zn) was examined. The quantity of total protein (mg protein/mg dry wt) in each sample and the measurement of MT were determined by the Lowry and silver (Ag)-saturation methods. Our results show ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784547
更新日期:1996-07-01 00:00:00
abstract::The effects of cadmium on the growth rate, catalase activity, and peroxisome proliferation in yeast, Candida albicans, were evaluated. The yeast growth was markedly inhibited by 1 mM cadmium at the initial hours. The toxic effect of cadmium on the cell growth persisted. The catalase activity of the cells treated with ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02789415
更新日期:1995-11-01 00:00:00
abstract::Multivariate statistical analysis has been applied to time series measurements of aerosol elemental composition from PIXE analysis of filter samples, and principal components have been resolved that represent distinct particle types in an external mixture in the atmosphere. In this study, it is argued that a combinati...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992673
更新日期:1990-07-01 00:00:00
abstract::Platelet-rich fibrin (PRF) is widely used blood-derived biomaterial which is directly applied to the surgical wounds. Depending on its autologous origin, PRF is thought as a safe material. However, it is not known to what extent the blood-derived toxins can be found in the PRF by considering the systemic exposure rate...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01695-6
更新日期:2019-10-01 00:00:00
abstract::Polaprezinc (zinc L-carnosine complex) is a tablet commonly prescribed for gastric ulcers in Japan. Recently, we reported the effects of polaprezinc on pressure ulcer healing at 4-week follow-up. We aimed to further evaluate the efficacy and safety of polaprezinc in 8-week treatment for chronic pressure ulcers. Patien...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1007/s12011-014-9943-5
更新日期:2014-06-01 00:00:00
abstract::We analyzed the effects of acute and chronic oral administration of monosodium L-glutamate (MSG) on serum iron (Fe) levels and total iron-binding capacity (TIBC) in piglets. In the first experiment, 12 piglets were randomly assigned to two groups: one fed a standard diet (SD) and the other fed an SD containing MSG (10...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9668-x
更新日期:2013-06-01 00:00:00
abstract::The interaction of the vanadyl (IV) cation with N-acetyl-D-galactosamine, D-galactosamine, and D-glucuronic acid has been investigated by electron absorption spectroscopy at different metal to ligand ratios and pH values. In the case of D-glucuronic acid, a more detailed study was undertaken, using differential IR spe...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02785436
更新日期:1996-02-01 00:00:00
abstract::Lipid disturbance induced by high-fat diet is a worldwide problem, and it can induce inflammation and oxidative stress in vivo. Zinc is considered as an antioxidant, anti-inflammatory agent. Since matrix metalloprotease 2 (MMP2) and matrix metalloprotease 9 (MMP9)'s expressions are changed under many pathological cond...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0367-7
更新日期:2015-12-01 00:00:00
abstract::Herein, we assess the antioxidant potential of core-shell yttrium oxide nanoparticles functionalized with ethylene glycol methacrylate phosphate (EGMP). The antioxidant properties of these nanoparticles were investigated in heat stressed models of 21 rats (heat stressed group, group B). Different samples of blood, ser...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02036-8
更新日期:2020-11-01 00:00:00
abstract::Trace element contamination in Chinese herbal medicines has been recognized as a potential health concern for consumers. To assess the health risk to the herb-consuming population, nine trace elements (Cu, Cd, Cr, Mo, Ni, Pb, Sr, Zn, and As) were investigated based on their concentrations in three common medicinal pla...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02539-4
更新日期:2021-01-03 00:00:00
abstract::High blood glucose concentration in diabetes induces free radical production and, thus, causes oxidative stress. Damage of cellular structures by free radicals play an important role in development of diabetic complications. In this study, we evaluated effects of sodium tungstate on enzymatic and nonenzymatic markers ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8537-0
更新日期:2010-08-01 00:00:00
abstract::Studies investigating the effects of Chromium (Cr) supplementation on unstressed broiler chickens have reported an inconsistent association between Cr supplementation and broiler chickens' responses. We conducted a dose-response meta-analysis of previous studies to assess the dose-response associations between Cr supp...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-021-02589-2
更新日期:2021-01-17 00:00:00
abstract::X-ray fluorescence experiments at the Photon Factory in Japan are described. An energy-dispersive X-ray fluorescence system was combined with various excitation modes, i.e., a continuum and a monochromatic excitation, which consist of a crystal monochromator or a wide band pass monochromator. These excitation modes pr...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02796677
更新日期:1987-04-01 00:00:00
abstract::X-ray Fluorescence (XRF) Analysis and Atomic Absorption Spectrophotometry (AAS) have been used in assessing heavy metal pollution from some gold mines in Ghana. The presence and levels of heavy metals in gold ore, gold tailings, inland waters, and river sediments have been determined. Using these techniques, the heavy...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992682
更新日期:1990-07-01 00:00:00
abstract::Trace elemental content was analysed in edible tissues of Mytilus galloprovincialis collected in five different sampling areas near the mouth of river Tagus estuary in Lisbon. The concentrations of essential elements (S, K, Ca, Fe, Cu, Zn, As, Br and Sr) were determined by energy-dispersive X-ray fluorescence (EDXRF) ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9974-y
更新日期:2014-06-01 00:00:00
abstract::In subjects with impaired insulin action, alterations of the serum sodium and potassium concentrations have been reported. The resulting cationic imbalance, along with the osmotic effect of the elevated sugar levels, could influence the course of diabetes mellitus management. Therefore, this study was conducted to com...
journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-011-9144-4
更新日期:2011-12-01 00:00:00
abstract::Quantitative analysis of follicular fluid and granulosa cells from small, medium and large antral atretic follicles of goat (Capra hircus) ovaries was conducted to study the alterations in trace elements viz zinc (Zn), copper (Cu), manganese (Mn), and iron (Fe). The zinc content was lower in the follicular fluid (0.99...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8700-7
更新日期:2011-06-01 00:00:00
abstract::A survey of mercury (Hg) and selenium (Se) contents was performed in fish collected from lakes located in two National Parks of the northern patagonian Andean range. Two native species, catfish (Diplomystes viedmensis) and creole perch (Percichthys trucha), and three introduced species, brown trout (Salmo trutta), rai...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-007-8059-6
更新日期:2008-04-01 00:00:00
abstract::During pregnancy, the demand for daily iodine increases by 50-70% which occurs to reach around 250 μg/day. Limited information is available on the association of high-risk pregnancy (HRP) with urinary iodine concentration (UIC) and variables such as socioeconomic factors. To analyze iodine nutritional status and socio...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02028-8
更新日期:2020-10-01 00:00:00
abstract::Placental type 3 iodothyronine deiodinase (D3) potentially protects the fetus from the elevated maternal thyroid hormones. Na(+)/I(-) symporter (NIS) is a plasma membrane glycoprotein, which mediates active iodide uptake. Our objectives were to establish the distribution of NIS and D3 gene expressions in the placenta ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9748-y
更新日期:2013-09-01 00:00:00
abstract::The effects of environmental lead on the immune system of young children were assessed by determining the peripheral blood lymphocytes CD3+, CD4+, CD8+, B(CD19+) counts, and natural killer (CD16+CD56+) cells in 35 preschool children whose mean blood lead level was 140.6 microg/L. The results were compared to an age- a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:105:1-3:019
更新日期:2005-07-01 00:00:00
abstract::Bioenvironmental trace elements play a vital role in plant, animal, and man metabolism. This study aims to determine trace element concentration in different parts (pods, pericarp, seeds, cotyledon, and taste) of the warm climate plant pigeon pea (Cajanus cajan L. Millsp.). The pigeon pea pods were collected from the ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02256-y
更新日期:2020-06-20 00:00:00
abstract::Two organoselenium compounds: xylitol selenious ester (xylitol-Se) and sucrose selenious ester (sucrose-Se) were synthesized, and their molecular structures were characterized in this study. In MTT assay, xylitol-Se and sucrose-Se showed cytostatic effects on human hepatocellular carcinoma cells SMMC-7221 in a dose-de...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9715-7
更新日期:2013-08-01 00:00:00
abstract::A study was conducted to determine the effect of dietary selenium (Se) concentration and source for broiler chickens on performance, nutrient digestibility, plasma Se, glutathione peroxidase (GPx) activity, and thiobarbituric acid reactive substances (TBARS). A total of 700 1-day-old broiler chicks were assigned to 7 ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01801-8
更新日期:2020-04-01 00:00:00
abstract::Heavy metals toxicity is a prevalent health problem particularly in developing countries. Mercury and cadmium are toxic elements that have no physiologic functions in human body. They should not be present in the human body by any concentration. Copper, on the other hand, is one of the elements that are essential for ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0525-y
更新日期:2016-06-01 00:00:00
abstract::The primary objective of the present study is analysis of hair trace elements content in children with communication disorder (CD) and autism spectrum disorder (ASD). A total of 99 children from control, CD, and ASD groups (n = 33) were examined. All children were additionally divided into two subgroups according to a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0878-x
更新日期:2017-06-01 00:00:00