On the antigenic relationship between the alpha A and alpha B subunits of alpha-crystallin in bovine lens.

abstract：:We established growth curves for Propionibacterium acnes isolates recovered from eyes with chronic postoperative endophthalmitis. The growth curve plotted the average of the duplicate bacterial concentration against time. The generation time for P. acnes calculated from the growth curves was approximately 5.1 hours. T...

journal_title：Current eye research

authors： Hall GS,Pratt-Rippin K,Meisler DM,Washington JA,Roussel TJ,Miller D

更新日期：1994-06-01 00:00:00

abstract：PURPOSE:This study sought to evaluate the efficacy of bevacizumab (Avastin), an anti-VEGF agent, in the reduction of corneal neovascularization in a rodent model, and compare between the effect of intraocular and subconjunctival injection. METHODS:Corneal neovascularization was induced by application of a mixture of 7...

journal_title：Current eye research

authors： Avisar I,Weinberger D,Kremer I

更新日期：2010-02-01 00:00:00

abstract：:Calcium permeability was significantly increased in lenses from rats 36 h following a single injection of a cataractogenic dose of sodium selenite (30 nmol/g body weight) and this permeability returned to control values by 72 h post-injection (PI). The greater Ca2+ permeability could be partially reversed by incubatin...

journal_title：Current eye research

authors： Wang Z,Bunce GE,Hess JL

更新日期：1993-03-01 00:00:00

abstract：:This study reports on serum interleukin 2-receptor (IL-2R) levels in uveitis patients. IL-2R is the mediator protein of interleukin 2 (IL-2), a mitogenetic cytokine of primarily immune cell interaction. Stimulated T-cells readily express IL-2R on their cell surface and release a soluble form into serum. The measuremen...

journal_title：Current eye research

authors： Arocker-Mettinger E,Asenbauer T,Ulbrich S,Grabner G

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:Robo1, a member of the roundabout (Robo) family, serves as neuronal guidance receptors and has been reported to mediate tumor angiogenesis. In this study, we investigated the function of Robo1 and its possible role in retinal angiogenesis in vitro and in vivo. METHODS:Expression of Robo1 in relation to retinal...

journal_title：Current eye research

authors： Huang L,Xu Y,Yu W,Li X,Liqun C,He X,Peiying H

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:We identified a novel mutation in Paired Box gene 6 (PAX6) and characterized its associated clinical features of severe ocular malformation in a Chinese family with congenital aniridia. METHODS:We studied two patients with aniridia from a Chinese family. All patients and noncarriers in this family underwent fu...

journal_title：Current eye research

authors： He Y,Pan Z,Luo F

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:To assess the rate of achieving optimal metabolic control among subjects with type 2 diabetes, to elucidate the influence of suboptimal control on diabetic retinopathy (DR) and to analyze the risk factors associated with DR in the subjects with suboptimal control. MATERIAL AND METHODS:A population-based, cross...

journal_title：Current eye research

authors： Raman R,Gupta A,Kulothungan V,Sharma T

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:C5a anaphylatoxin is a potent inflammatory mediator that acts on polymorphonuclear cells (PMN) and monocytes via C5a receptors (C5aR). It mediates chemotaxis of both cell types and stimulates cytokine release from the latter. To investigate whether C5a can act on retinal pigment epithelial (RPE) cells, we exami...

journal_title：Current eye research

authors： Fukuoka Y,Medof EM

更新日期：2001-11-01 00:00:00

abstract：PURPOSE:To characterize the possible cytotoxic effects of oxysterols (7beta-hydroxycholesterol (7beta-OH), 25-hydroxycholesterol (25-OH)) in human retinal pigment epithelial cells (ARPE-19) and to detail the relationships between some of these effects. METHODS:ARPE-19 cells were treated with 7beta-OH and 25-OH. Cell v...

journal_title：Current eye research

authors： Malvitte L,Montange T,Vejux A,Joffre C,Bron A,Creuzot-Garcher C,Lizard G

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:To determine the plasma levels of the sulfur-containing amino-acids homocysteine, cysteine, cysteinylglycine, glutamylcysteine, glutathione, and taurine in patients with central retinal vein occlusion (CRVO) and in healthy subjects and to ascertain whether there are statistically significant differences between...

journal_title：Current eye research

authors： Pinna A,Zinellu A,Franconi F,Carru C

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:1) To elucidate the role of collector channels in the aqueous humor outflow pathway 2) To suggest anatomic and functional methods of imaging collector channels in-vitro and in-vivo and 3) To discuss the role of such imaging modalities in the surgical management of glaucoma. METHODS:A thorough literature sea...

journal_title：Current eye research

authors： M Elhusseiny A,Jamerson EC,Menshawey R,Tam EK,El Sayed YM

更新日期：2020-10-01 00:00:00

abstract：:Purpose: The goal of this work was to determine whether the retinal tissue perfusion (RTP) is impaired in patients with multiple sclerosis (MS). Methods: Seventy-four patients [66 relapsing-remitting MS (RRMS) and 8 clinically isolated syndrome (CIS)] and 74 age- and gender-matched healthy controls were recruited. RTP...

journal_title：Current eye research

authors： Liu Y,Delgado S,Jiang H,Lin Y,Hernandez J,Deng Y,Gameiro GR,Wang J

更新日期：2019-10-01 00:00:00

abstract：PURPOSE:Age-related macular degeneration (AMD) is the most common cause of visual loss. The dry AMD is characterized by retinal pigment epithelium (RPE) death and changes in AMD lead to severe loss of vision. Coumarin-derived esculetin has a number of therapeutic and pharmacological effects such as anti-inflammatory an...

journal_title：Current eye research

authors： Ozal SA,Turkekul K,Gurlu V,Guclu H,Erdogan S

更新日期：2018-09-01 00:00:00

abstract：:We have examined the T cell specificity of a Lewis rat T cell line (R208) specific for a pathogenic, 123 residue cyanogen bromide produced peptide of bovine S-antigen by using two independent sets of overlapping synthetic peptides representing the entire length of the 123 residue fragment. S-antigen, a 48 kDa immunopa...

journal_title：Current eye research

authors： Fling SP,Gregerson DS,Obritsch WF,Boyce-Jacino M,Merryman CF,Donoso LA

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:Rhodopsin is a zinc-binding protein. We investigated the effect of low concentrations of zinc on the initial phosphorylation of rhodopsin. METHODS:Dark-adapted bovine rod outer segments (ROS) were incubated with (gamma 32P) ATP and 5 mM magnesium in the presence and absence of micromolar amounts of zinc. The R...

journal_title：Current eye research

authors： Shuster TA,Martin F,Nagy AK

更新日期：1996-10-01 00:00:00

abstract：:Purpose: Notch signaling plays a vital role in the differentiation and proliferation of corneal epithelial cells from limbal stem cells. The temporal regulation of Notch signaling during this differentiation remains unknown. Hence, we investigated the importance of temporal activation/blockage of Notch signaling durin...

journal_title：Current eye research

authors： Dhamodaran K,Subramani M,Krishna L,Matalia H,Jayadev C,Chinnappaiah N,Shetty R,Das D

更新日期：2020-04-01 00:00:00

abstract：PURPOSE:To determine the role of matrix metalloproteinase 9 (MMP9) in advanced glycation end-products (AGEs) induced damage to blood-retinal barrier (BRB) and the therapeutic effects of minocycline, an MMP inhibitor, against the BRB damages. METHODS:Forty-eight Sprague Dawley rats were randomly assigned to 3 groups (1...

journal_title：Current eye research

authors： Chen YD,Xu X,Xia X,Wu H,Liu K,Zheng Z,Zhu D

更新日期：2008-11-01 00:00:00

abstract：PURPOSE:Statins have been shown to reduce ocular inflammation in animal models of uveitis and to prevent development of uveitis in observational studies. There have been no experimental human studies evaluating statins' efficacy and safety in uveitis. In this study, we aimed to investigate efficacy and safety of simvas...

journal_title：Current eye research

authors： Shirinsky IV,Biryukova AA,Shirinsky VS

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To quantitatively measure the flow, nonflow, density, and foveal avascular zone (FAZ) assessment tool parameters of optical coherence tomography angiography (OCTA) in patients with nonocular Behcet's Disease (BD), and to compare the results with those obtained in healthy controls. METHODS:FAZ parameters, flow ...

journal_title：Current eye research

authors： Goker YS,Yılmaz S,Kızıltoprak H,Tekin K,Demir G

更新日期：2019-02-01 00:00:00

abstract：:In these experiments we characterize rabbit and bovine corneal endothelia cell cultured on microporous membrane filters (0.6cm2). Cell cultured bovine or rabbit corneal endothelial cells (subcultures 1-3) were seeded onto Millicell-HA filter inserts. Electrical resistance measured across the cultured monolayers increa...

journal_title：Current eye research

authors： Geroski DH,Hadley A

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:We located immunohistochemically the matrix metalloproteinases (MMP) -1, -2, -3 and -9 and the tissue inhibitors of matrix metalloproteinases (TIMP) -1 and -2 in the fibrous capsule of patients with intraocular lenses (IOLs). METHODS:During vitreoretinal surgery in 10 patients we obtained post-cataract surgery...

journal_title：Current eye research

authors： Kawashima Y,Saika S,Miyamoto T,Yamanaka O,Okada Y,Tanaka S,Ohnishi Y

更新日期：2000-12-01 00:00:00

abstract：:Interleukin 4 (IL-4) may play a role in the development of allergic disease. We questioned whether IL-4 related phenomenon occurred on the surface of the conjunctiva during allergic conjunctivitis. Ten patients with cedar pollen-allergic conjunctivitis and 10 patients with postsurgical conjunctivitis were enrolled in ...

journal_title：Current eye research

authors： Fujishima H,Saito I,Takeuchi T,Shinozaki N,Tsubota K

更新日期：1996-02-01 00:00:00

abstract：:Membrane response to the various temperatures as one of the external factors was investigated in the lenses of the poikilothermal animal and the homothermal animal. The rainbow trout lens was used as the poikilothermal material and the rat lens as the homothermal material. The rainbow trout lens maintained in vitro it...

journal_title：Current eye research

authors： Iwata S

更新日期：1985-04-01 00:00:00

abstract：PURPOSE:To compare the abilities of balanced salt solution, BSS Plus and Hartmann's lactated Ringer's (HLR) solution to maintain the viability of retinal vascular endothelial cells (RVEC) in vitro. METHODS:Cultured retinal vascular endothelial cells were suspended in each irrigating solution for four hours. Viability ...

journal_title：Current eye research

authors： Mourad KM,Edelhauser HF,Capone A Jr,Lynn MJ,Geroski DH

更新日期：1997-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to characterize swelling pressure-thickness, swelling pressure-hydration and hydration-thickness relations of porcine cornea. METHODS:Mechanical compression tests and free swelling experiments were performed on porcine cornea. A rheometer (DHR-2, TA Instruments) with a thermally contr...

journal_title：Current eye research

authors： Hatami-Marbini H,Etebu E,Rahimi A

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:A quick, simple, and efficient extraction technique was developed for the removal of protein from soft hydrophilic contact lenses. METHODS:An extraction solvent consisting of a 50:50 mix of 0.2% trifluoroacetic acid and acetonitrile was used to remove protein from in vitro laboratory-deposited and human-worn c...

journal_title：Current eye research

authors： Keith D,Hong B,Christensen M

更新日期：1997-05-01 00:00:00

abstract：PURPOSE:To evaluate changes in biometric parameters in myopic eyes. MATERIALS AND METHODS:412 eyes of 412 young myopic patients underwent ophthalmic examinations including assessments of refractive error, axial length (AL), anterior chamber depth (ACD), and central corneal thickness (CCT). By using spectral domain opt...

journal_title：Current eye research

authors： Chung HJ,Park CK

更新日期：2016-12-01 00:00:00

abstract：:About 55% of the acyl groups of dog and human vitreous are unsaturated fatty acids. The major components are oleate (18:1, n-9) and arachidonate (20:4, n-6) with moderate amounts of linoleate (18:2, n-6) and docosahexaenoate (22:6, n-3). Palmitate (16:0) and stearate (18:0) are the major saturated fatty acids. There a...

journal_title：Current eye research

authors： Reddy TS,Birkle DL,Packer AJ,Dobard P,Bazan NG

更新日期：1986-06-01 00:00:00

abstract：PURPOSE:To evaluate central corneal thickness (CCT) and corneal volume (CV) in healthy eyes using swept source anterior segment optical coherence tomography (SS-AS-OCT) and other devices. METHODS:Thirty-three healthy right eyes of 33 subjects were investigated. CCT was measured with SS-AS-OCT, rotating Scheimpflug cam...

journal_title：Current eye research

authors： Fukuda R,Usui T,Miyai T,Mori Y,Miyata K,Amano S

更新日期：2013-05-01 00:00:00

abstract：:Purpose: To investigate to what extent the OSDI can be utilized as a discriminative test for clinical findings. Methods: One thousand and ninety patients with dry eye disease (DED) were consecutively included and examined for osmolarity, tear film break-up time (TFBUT), ocular protection index (OPI), ocular surface st...

journal_title：Current eye research

authors： Yazdani M,Chen X,Tashbayev B,Utheim ØA,Ræder S,Hua Y,Eidet JR,Stojanovic A,Dartt DA,Utheim TP

更新日期：2019-09-01 00:00:00