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Paratesticular neuroblastoma with N-myc activation.

Abstract：

:The authors describe a case of disseminated neuroblastoma discovered as a paratesticular tumor in a 7-month-old boy. The ectopic adrenal tissues adjacent to the paratesticular tumor and multiple lesions in the adrenal gland and skin suggested the possibility of multifocal primary tumors. Although infantile neuroblastoma diagnosed at less than 1 year of age generally responds well to treatment irrespective of distant metastases, metastases developed, and the boy died of disease within 7 months. All multiple lesions had amplification and overexpression of the N-myc protooncogene, which might explain the aggressive phenotype of this rare case.

journal_name

J Pediatr Surg

journal_title

Journal of pediatric surgery

authors

Matsunaga T,Takahashi H,Ohnuma N,Tanabe M,Yoshida H,Enomoto H,Horie H,Shirasawa H,Simizu B

doi

10.1016/0022-3468(93)90117-4

subject

Has Abstract

pub_date

1993-12-01 00:00:00

pages

1612-4

issue

12

eissn

0022-3468

issn

1531-5037

pii

0022-3468(93)90117-4

journal_volume

28

pub_type

杂志文章

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