ABP50: an actin-binding elongation factor 1 alpha from Dictyostelium discoideum.

Abstract:

:ABP50 is a polypeptide elongation factor 1 alpha from Dictyostelium that is associated with the actin cytoskeleton. Upon chemotactic stimulation, ABP50 undergoes a dramatic cytoplasmic redistribution into newly formed surface projections and in vitro binds to and bundles actin filaments. Many questions are raised by this interaction pertaining to the spatiotemporal regulation of protein synthesis and cytoskeletal organization by extracellular signals.

journal_name

J Cell Biochem

authors

Edmonds BT

doi

10.1002/jcb.240520204

subject

Has Abstract

pub_date

1993-06-01 00:00:00

pages

134-9

issue

2

eissn

0730-2312

issn

1097-4644

journal_volume

52

pub_type

杂志文章,评审
  • Site-specific mutagenesis of cDNA clones expressing a poliovirus proteinase.

    abstract::The cleavage of poliovirus precursor polypeptides occurs at specific amino acid pairs that are recognized by viral proteinases. Most of the polio-specific cleavages occur at glutamine-glycine (Q-G) pairs that are recognized by the viral-encoded proteinase 3C (formerly called P3-7c). In order to carry out a defined mol...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.240330105

    authors: Semler BL,Johnson VH,Dewalt PG,Ypma-Wong MF

    更新日期:1987-01-01 00:00:00

  • Involvement of calcium-dependent protein kinase C in arsenite-induced genotoxicity in Chinese hamster ovary cells.

    abstract::Arsenic is the first metal to be identified as a human carcinogen. Arsenite, one inorganic form of arsenic, has been found to induce sister chromatid exchange, chromosome aberrations, and gene amplification in a variety of in vitro systems. In this study of arsenite-induced genotoxicity represented a micronuclei produ...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:

    authors: Liu YC,Huang H

    更新日期:1997-03-01 00:00:00

  • Immunological comparison of desmosomal components from several bovine tissues.

    abstract::A panel of monoclonal antibodies and conventional antisera directed against desmosomal proteins from bovine muzzle epidermis was used to identify immunologically related proteins from two other bovine stratified squamous epithelia, cornea and esophagus. Desmosome-enriched tissue fractions were prepared from epidermis,...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.240260104

    authors: Giudice GJ,Cohen SM,Patel NH,Steinberg MS

    更新日期:1984-01-01 00:00:00

  • D224V and S128Y mutation in FSHRED influence thumb movement differentially: An intricate insight gained by short-term molecular dynamics simulation.

    abstract::Follicle-stimulating hormone-follicle-stimulating hormone receptor (FSH-FSHR) interaction is one of the most thoroughly studied signaling pathways primarily because of being implicated in sexual reproduction in mammals by way of maintaining gonadal function and sexual fertility. Despite material advances in understand...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.28044

    authors: Gharemirshamlu FR,Afsar M,Mokhdomi TA,Amin A,Bukhari S,Krishnan A,Kumar CV,Bamdad K,Patel TN,Qadri RA,Chikan NA,Shabir N

    更新日期:2018-11-02 00:00:00

  • NS5ATP9 Promotes Beclin 1-Dependent Starvation-Induced Autophagy of Hepatoblastoma Cells.

    abstract::NS5ATP9, a gene up-regulated by NS5A, plays a crucial oncogenic role in several types of human tumours. However, the underlying mechanisms remain unclear. Autophagy, an evolutionarily conserved catabolic process, maintains cellular homeostasis under stress conditions, such as starvation, and plays a crucial role in tu...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.25111

    authors: Quan M,Liu S,Wang Q,Li G,Zhang Y,Feng S,Liang J,Cheng J

    更新日期:2015-08-01 00:00:00

  • Overexpression of miR-301a-3p promotes colorectal cancer cell proliferation and metastasis by targeting deleted in liver cancer-1 and runt-related transcription factor 3.

    abstract::Colorectal cancer (CRC) is the third most common type of cancer. MicroRNAs have been reported to participate in the progression of various cancers. In previous studies, miR-301a-3p expression was shown to be upregulated in CRC tissues. However, the underlying mechanism of miR-301a-3p in CRC has not yet been elucidated...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.27894

    authors: Zhang L,Zhang Y,Zhu H,Sun X,Wang X,Wu P,Xu X

    更新日期:2019-04-01 00:00:00

  • A shared comparison of diabetes mellitus and neurodegenerative disorders.

    abstract::Diabetes mellitus (DM), one of the most prevalent metabolic diseases in the world population, is associated with a number of comorbid conditions including obesity, pancreatic endocrine changes, and renal and cardio-cerebrovascular alterations, coupled with peripheral neuropathy and neurodegenerative disease, some of t...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.28094

    authors: Morsi M,Kobeissy F,Magdeldin S,Maher A,Aboelmagd O,Johar D,Bernstein L

    更新日期:2019-09-01 00:00:00

  • Transcriptional regulation of basic fibroblast growth factor gene expression in capillary endothelial cells.

    abstract::The growth of capillary endothelial cells (BCE) is an important regulatory step in the formation of capillary blood vessels. In vivo, the proliferation of these cells is stringently controlled. In vitro they can be stimulated by polypeptide growth factors, such as acidic fibroblast growth factor (aFGF) and basic fibro...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.240470209

    authors: Weich HA,Iberg N,Klagsbrun M,Folkman J

    更新日期:1991-10-01 00:00:00

  • Network Meta-Analysis on the Effects of DNA Damage Response-Related Gene Mutations on Overall Survival of Breast Cancer Based on TCGA Database.

    abstract::The study was conducted for comparing the effects of 12 DNA damage response gene mutations (CHEK1, CHEK2, RAD51, BRCA1, BRCA2, MLH1, MSH2, ATM, ATR, MDC1, PARP1, and FANCF) on the overall survival (OS) of breast cancer (BC) patients. We searched the Cancer Genome Atlas (TCGA) database from inception to September 2016....

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章,meta分析

    doi:10.1002/jcb.26140

    authors: Liu C,Chang H,Li XH,Qi YF,Wang JO,Zhang Y,Yang XH

    更新日期:2017-12-01 00:00:00

  • Insights into nuclear localization and dynamic association of CD38 in Raji and K562 cells.

    abstract::CD38 is a type II transmembrane glycoprotein found mainly on the plasma membrane involved in the metabolism of cADPR and NAADP, two nucleotides with calcium mobilizing activity independent of inositol trisphosphate. Recent data report the presence of CD38 in different cellular compartments raising new questions about ...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.21510

    authors: Trubiani O,Guarnieri S,Eleuterio E,Di Giuseppe F,Orciani M,Angelucci S,Di Primio R

    更新日期:2008-03-01 00:00:00

  • Vanadium induces apoptosis and modulates the expressions of metallothionein, Ki-67 nuclear antigen, and p53 during 2-acetylaminofluorene-induced rat liver preneoplasia.

    abstract::Our previous studies have shown that vanadium, a dietary micronutrient, has an inhibitory effect against experimentally induced rat hepatocarcinogenesis. In this study, we evaluated the role of vanadium on some potential protein expression markers of carcinogenesis, such as metallothionein (MT), an intracellular metal...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.20304

    authors: Chakraborty T,Samanta S,Ghosh B,Thirumoorthy N,Chatterjee M

    更新日期:2005-03-01 00:00:00

  • Adsorption of glycosaminoglycans to the cell surface is responsible for cellular donnan effects.

    abstract::In previous publications, we showed that extracellular glycosaminoglycans reduced the membrane potential, caused cell blebbing and swelling and decreased the intracellular pH independently of cell surface receptors. These phenomena were explained by Donnan effects. The effects were so large that they could not be attr...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.24791

    authors: Hagenfeld D,Kathagen N,Prehm P

    更新日期:2014-07-01 00:00:00

  • Undifferentiated Neuroblastoma Cells Are More Sensitive to Photogenerated Oxidative Stress Than Differentiated Cells.

    abstract::Neuroblastoma is one of the most aggressive cancers and has a complex form of differentiation. We hypothesized that advanced cellular differentiation may alter the susceptibility of neuroblastoma to photodynamic treatment (PDT) and confer selective survival advantage. We demonstrated that hematoporphyrin uptake by und...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.25165

    authors: Lee CI,Perng JH,Chen HY,Hong YR,Wang JJ

    更新日期:2015-09-01 00:00:00

  • Interactions between muscle tissues and bone metabolism.

    abstract::Sarcopenia and osteoporosis have recently been noted for their relationship with locomotive syndrome and increased number of older people. Sarcopenia is defined by decreased muscle mass and impaired muscle function, which may be associated with frailty. Several clinical data have indicated that increased muscle mass i...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.25040

    authors: Kawao N,Kaji H

    更新日期:2015-05-01 00:00:00

  • Upregulation of PRMT6 by LPS suppresses Klotho expression through interaction with NF-κB in glomerular mesangial cells.

    abstract::Lipopolysaccharide (LPS) released from gram-negative bacteria stimulates immune responses in infected cells. Epigenetic modifications such as DNA methylation and protein methylation modulate LPS-induced innate immune gene expressions. Expression of the Klotho protein decreased with LPS treatment in rats. In a cellular...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.26511

    authors: Tsai KD,Lee WX,Chen W,Chen BY,Chen KL,Hsiao TC,Wang SH,Lee YJ,Liang SY,Shieh JC,Lin TH

    更新日期:2018-04-01 00:00:00

  • N-acetyl-L-cysteine inhibits bleomycin induced apoptosis in malignant testicular germ cell tumors.

    abstract::Antioxidants may prevent apoptosis of cancer cells via inhibiting reactive oxygen species (ROS). However, to date no study has been carried out to elucidate the effects of strong antioxidant N-acetylcysteine (NAC) on Bleomycin induced apoptosis in human testicular cancer (NTERA-2, NT2) cells. For this reason, we studi...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.24510

    authors: Kucuksayan E,Cort A,Timur M,Ozdemir E,Yucel SG,Ozben T

    更新日期:2013-07-01 00:00:00

  • Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell.

    abstract::Lysyl oxidase (LO) plays a critical role in the formation and repair of the extracellular matrix (ECM) by oxidizing lysine residues in elastin and collagen, thereby initiating the formation of covalent crosslinkages which stabilize these fibrous proteins. Its catalytic activity depends upon both its copper cofactor an...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章,评审

    doi:10.1002/jcb.10413

    authors: Kagan HM,Li W

    更新日期:2003-03-01 00:00:00

  • Vascular progenitors derived from murine bone marrow stromal cells are regulated by fibroblast growth factor and are avidly recruited by vascularizing tumors.

    abstract::Bone marrow-derived stromal cells (BMSC) possess a population of vascular progenitor cells that enable them to acquire a histology and immunophenotype coherent with endothelial cells (EC). Recent evidence indicates that a hypoxic environment such as that encountered in tumor masses regulates BMSC angiogenic properties...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.10763

    authors: Annabi B,Naud E,Lee YT,Eliopoulos N,Galipeau J

    更新日期:2004-04-15 00:00:00

  • Oxygen-bound Hell's gate globin I by classical versus LB nanotemplate method.

    abstract::X-ray atomic structure of recombinant Hell's gate globin I (HGbI) from Methylacidophilum infernorum was calculated from the X-ray diffraction data of two different types of crystals: obtained by classical hanging drop and by LB nanotemplate method under the same crystallization conditions. After the accurate compariso...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.24131

    authors: Pechkova E,Scudieri D,Belmonte L,Nicolini C

    更新日期:2012-07-01 00:00:00

  • Inorganic phosphate as a signaling molecule in osteoblast differentiation.

    abstract::The spatial and temporal coordination of the many events required for osteogenic cells to create a mineralized matrix are only partially understood. The complexity of this process, and the nature of the final product, demand that these cells have mechanisms to carefully monitor events in the extracellular environment ...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章,评审

    doi:10.1002/jcb.10622

    authors: Beck GR Jr

    更新日期:2003-10-01 00:00:00

  • Decreased activity of acetyl-CoA carboxylase during chemically induced neutrophilic differentiation of human promyelocytic leukemia cells.

    abstract::In order to better understand the mechanism by which changes in the fatty acid composition of cellular lipids occur in leukemia cell lines induced to differentiate, the activity of the first enzyme of fatty acid biosynthesis, acetyl-CoA carboxylase (EC 6.4.1.2) was measured in HL-60 promyelocytic leukemia cells before...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.240260203

    authors: Fischkoff SA,Papuchis GC,Nickols WA

    更新日期:1984-01-01 00:00:00

  • Design of inhibitory peptide targeting Toxoplasma gondii RON4-human β-tubulin interactions by implementing structural bioinformatics methods.

    abstract::Toxoplasma gondii an obligate intracellular parasite causes toxoplasmosis in homeothermic animals. Host invasion of this parasite is mediated by the formation of Moving Junction (MJ) complex which encompasses a network of microneme and Rhoptry Neck proteins (RONs) 2/4/5/8. Among these proteins, RON4 is the only cytoso...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.26480

    authors: Vetrivel U,Nagarajan H,Thirumudi I

    更新日期:2018-04-01 00:00:00

  • Gastrokine 1 regulates NF-κB signaling pathway and cytokine expression in gastric cancers.

    abstract::Gastrokine 1 (GKN1) plays an important role in the gastric mucosal defense mechanism and also acts as a functional gastric tumor suppressor. In this study, we examined the effect of GKN1 on the expression of inflammatory mediators, including NF-κB, COX-2, and cytokines in GKN1-transfected AGS cells and shGKN1-transfec...

    journal_title:Journal of cellular biochemistry

    pub_type: 临床试验,杂志文章

    doi:10.1002/jcb.24524

    authors: Yoon JH,Cho ML,Choi YJ,Back JY,Park MK,Lee SW,Choi BJ,Ashktorab H,Smoot DT,Nam SW,Lee JY,Park WS

    更新日期:2013-08-01 00:00:00

  • Serological protein profiling of neuroblastoma by ProteinChip SELDI-TOF technology.

    abstract::Serological proteins of neuroblastoma were profiled and analyzed by ProteinChip-SELDI-TOF MS technology with five types of protein chips. By comparing with normal control, a number of protein or polypeptide signals were found significantly and consistently different in their intensities (expression levels) in tumor se...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.20417

    authors: He QY,Zhu R,Ren Y,Tam PK,Chiu JF

    更新日期:2005-05-01 00:00:00

  • Long Non-Coding RNA MALAT1 Promotes Proliferation, Angiogenesis, and Immunosuppressive Properties of Mesenchymal Stem Cells by Inducing VEGF and IDO.

    abstract::Mesenchymal stem cells (MSCs) play an important role in regulating angiogenesis and immune balance. The abnormal MSCs in proliferation and function were reported at maternal fetal interface in patients with pre-eclampsia (PE). Long non-coding RNA MALAT1 was known to regulate the function of trophoblast cells. However,...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.25927

    authors: Li X,Song Y,Liu F,Liu D,Miao H,Ren J,Xu J,Ding L,Hu Y,Wang Z,Hou Y,Zhao G

    更新日期:2017-09-01 00:00:00

  • Tendon explant cultures to study the communication between adipose stem cells and native tendon niche.

    abstract::Poor clinical outcomes of tendon repair, together with limited regenerative capacity of the tissue, have triggered the search for alternative regenerative medicine strategies. Human adipose-derived stem cells (hASCs) are being investigated as a promising cell source in contributing for tendon repopulation and reconstr...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.26573

    authors: Costa-Almeida R,Berdecka D,Rodrigues MT,Reis RL,Gomes ME

    更新日期:2018-04-01 00:00:00

  • C-myc deregulation during transformation induction: involvement of 7SK RNA.

    abstract::The process of oncogenic transformation has been widely studied but is still poorly understood. We have focused on the mechanism of deregulation of the c-myc gene during transformation of a temperature-sensitive SV40-transformed mouse cell line. Run-on transcription assays showed that the two c-myc minor promoters, P1...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-4644(199702)64:2<313::aid-jcb13

    authors: Luo Y,Kurz J,MacAfee N,Krause MO

    更新日期:1997-02-01 00:00:00

  • The function of BED finger domain of Zbed3 in regulating lung cancer cell proliferation.

    abstract::Zbed3, a BED finger domain-containing protein was found to promote cancer proliferation by regulating β-catenin expression through interacting with Axin. But whether and how BED finger domain function in regulating cancer proliferation is unknown. We constructed five mutants of Zbed3, which lacks the Axin-Zbed3 bindin...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.28498

    authors: Liu H,Shi X,Fan X,Zhang D,Jiang B,Zhao Y,Fan C

    更新日期:2019-08-01 00:00:00

  • Reversal of BCRP-mediated multidrug resistance by stable expression of small interfering RNAs.

    abstract::Breast cancer resistance protein (BCRP) is an ATP-binding cassette multidrug transporter that confers resistance to various anticancer drugs like Mitoxantrone. Overexpression of BCRP confers multidrug resistance (MDR) in cancer cells and is a frequent impediment to successful chemotherapy. For stable reversal of BCRP-...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.21276

    authors: Lv H,He Z,Liu X,Yuan J,Yu Y,Chen Z

    更新日期:2007-09-01 00:00:00

  • Roles of CTPL/Sfxn3 and Sfxn family members in pancreatic islet.

    abstract::Pancreatic AR42J cells have the feature of pluripotency of the precursor cells of the gut endoderm. Betacellulin (BTC) and activin A (Act) convert them into insulin-secreting cells. Using mRNA differential display techniques, we have identified a novel mitochondrial transporter, which is highly expressed during the co...

    journal_title:Journal of cellular biochemistry

    pub_type: 杂志文章

    doi:10.1002/jcb.20481

    authors: Yoshikumi Y,Mashima H,Ueda N,Ohno H,Suzuki J,Tanaka S,Hayashi M,Sekine N,Ohnishi H,Yasuda H,Iiri T,Omata M,Fujita T,Kojima I

    更新日期:2005-08-15 00:00:00