Tendon explant cultures to study the communication between adipose stem cells and native tendon niche.

abstract：:The influence of concentration of simvastatin (SIM) on free radicals in A-2058 human melanoma malignum cells was studied. The proliferation assay for melanoma A-2058 cells with SIM in concentration range from 0.1 to 20 µM was performed. SIM in the concentrations of 0.1, 0.3, and 1 μM only slightly changed the growth o...

journal_title：Journal of cellular biochemistry

authors： Zdybel M,Chodurek E,Pilawa B

更新日期：2018-09-11 00:00:00

abstract：:The stimulation of cultured guinea pig alveolar macrophages by the chemotactic peptide N-formyl-L-methionyl-L-leucyl-L-phenylalanine, or by the phospholipid inflammatory mediator platelet activating factor (PAF) induced an increase in arachidonic acid release and its cyclooxygenase products. This release, which was mi...

journal_title：Journal of cellular biochemistry

authors： Kadiri C,Masliah J,Bachelet M,Vargaftig BB,Béréziat G

更新日期：1989-06-01 00:00:00

abstract：:Activation of cytosolic phosphoinositide-3 kinase (PI-3K) signaling pathway has been well established to regulate gene expression, cell cycle, and survival by feeding signals to the nucleus. In addition, strong evidences accumulated over the past few years indicate the presence of an autonomous inositol lipid metaboli...

journal_title：Journal of cellular biochemistry

authors： Kikani CK,Dong LQ,Liu F

更新日期：2005-12-15 00:00:00

abstract：:The cadherin/catenin complex plays a key role in the initiation of cell-cell recognition, and adhesion, and the elaboration of structural and functional organization in multicellular tissues and organs. It is associated with tumor metastasis and also acts as an "invasion suppressor" of cancer cells. Nasopharyngeal car...

journal_title：Journal of cellular biochemistry

authors： Lou PJ,Chen WP,Lin CT,DePhilip RM,Wu JC

更新日期：1999-11-01 00:00:00

abstract：:Toxoplasma gondii excreted-secreted antigens (ESA) could lead to the fetal abortion especially in the early stage of pregnancy. Deficit in regulatory T cells is a critical event in the fetal abortion. Transcription factor forkhead box p3 (Foxp3) mediates differentiation and functional roles on regulatory T cells. Prev...

journal_title：Journal of cellular biochemistry

authors： Chen J,Huang C,Zhu D,Chen L,Wang J,Sun X,Hu L,Duan Y

更新日期：2018-12-01 00:00:00

abstract：:It has drawn a lot of attention to target signal transducer and activator of transcription 3 (STAT3) as a potential strategy for cancer therapeutics. Using several myelogenous cell lines, the effect of genipin (an active compound of Gardenia fruit) on the STAT3 pathway and apoptosis was investigated. Genipin suppresse...

journal_title：Journal of cellular biochemistry

authors： Lee JC,Ahn KS,Jeong SJ,Jung JH,Kwon TR,Rhee YH,Kim SH,Kim SY,Yoon HJ,Zhu S,Chen CY,Kim SH

更新日期：2011-06-01 00:00:00

abstract：:The MDMX gene product is related to the MDM2 oncoprotein, both of which interact with the p53 tumor suppressor. A novel transcript of the MDMX gene has been previously identified that has a short internal deletion of 68 base pairs, producing a shift in the reading frame after codon 114, resulting in the inclusion of 1...

journal_title：Journal of cellular biochemistry

authors： Rallapalli R,Strachan G,Tuan RS,Hall DJ

更新日期：2003-06-01 00:00:00

abstract：:Previous studies demonstrated that, upon attaining confluence, a clone of the renal epithelial cell, LLC-PK1, expressed progressively binding sites for the lectin Dolichos biflorus agglutinin (DBA) at the apical cell surface. Activation of cAMP-dependent protein kinase enhanced surface expression dramatically. The goa...

journal_title：Journal of cellular biochemistry

authors： Amsler K

更新日期：1993-08-01 00:00:00

abstract：:Acid-electrolyzed functional water (FW) is obtained through the electrolysis of sodium chloride solution. Stimulation of the human fibroblastic cell line HeLa by FW led to the augmented secretion of basic fibroblast growth factor (bFGF). Immunoprecipitation followed by Western blot analysis revealed that both high and...

journal_title：Journal of cellular biochemistry

authors： Motozawa K,Motoyoshi M,Saiki A,Sasaki H,Shimizu N,Asano M

更新日期：2018-09-01 00:00:00

abstract：:Previous work from this laboratory indicates a role for the complement component C5 in neuroprotection against excitotoxicity. In the present study, we tested the hypothesis that the C5-derived anaphylatoxin C5a protects against kainic acid (KA)-induced neurodegeneration and investigated the mechanism of C5a neuronal ...

journal_title：Journal of cellular biochemistry

authors： Osaka H,Mukherjee P,Aisen PS,Pasinetti GM

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:The impact of aberrant expression of miRNAs, small noncoding RNAs of 19 to 23 nucleotide, has been reported in different types of cancer, such as breast cancer. Authors aim to investigate the role of circulating miRNA-335 as a diagnostic and prognostic marker for breast cancer. MATERIALS AND METHODS:miRNA-3...

journal_title：Journal of cellular biochemistry

authors： Swellam M,Mahmoud MS,Hashim M,Hassan NM,Sobeih ME,Nageeb AM

更新日期：2019-06-01 00:00:00

abstract：:The CRISPR-Cas system is a key technology for genome editing and regulation in a wide range of organisms and cell types. Recently, CRISPR-Cas-based diagnostic platform has shown idealistic properties for pathogen detection. Integrating the CRISPR-Cas platform along with lateral flow system allows rapid, sensitive, spe...

journal_title：Journal of cellular biochemistry

authors： Khambhati K,Bhattacharjee G,Singh V

更新日期：2019-03-01 00:00:00

abstract：:Lysophosphatidic acid (LPA) elicits diverse cellular responses through cell surface LPA receptors in nervous system-derived cells and cell lines. The developing nervous system is one of the major loci for LPA receptor expression. Recent studies have also revealed that metabolic pathways of LPA are present in the nervo...

journal_title：Journal of cellular biochemistry

authors： Fukushima N

更新日期：2004-08-01 00:00:00

abstract：:Vascular smooth muscle cells (SMCs), the major cellular constituent of an artery, synthesize the bulk of fibrillar collagens, including type V/XI, which regulates heterotypic collagen fibril assembly. Basic fibroblast growth factor (bFGF) is a heparin-binding polypeptide growth factor that has been implicated in impor...

journal_title：Journal of cellular biochemistry

authors： Kypreos KE,Sonenshein GE

更新日期：1998-02-01 00:00:00

abstract：:Alpha-fetoprotein (AFP) is one of the major serum proteins in the early life of mammals. We have previously identified a novel cis-acting element designated as DAS at the 5'-flanking region of the AFP gene and demonstrated that the DAS sequence can be specifically recognized by nuclear protein DAP-II in AFP-producing ...

journal_title：Journal of cellular biochemistry

authors： Jiao R,He QY,Chen H,Hua Z,Jiao Q,Chiu JF

更新日期：2006-08-01 00:00:00

abstract：:The process of oncogenic transformation has been widely studied but is still poorly understood. We have focused on the mechanism of deregulation of the c-myc gene during transformation of a temperature-sensitive SV40-transformed mouse cell line. Run-on transcription assays showed that the two c-myc minor promoters, P1...

journal_title：Journal of cellular biochemistry

authors： Luo Y,Kurz J,MacAfee N,Krause MO

更新日期：1997-02-01 00:00:00

abstract：:The core binding factor (CBF) acute myeloid leukemias (AMLs) are a prognostically distinct subgroup that includes patients with the inv(16) and t(8:21) chromosomal rearrangements. Both of these rearrangements result in the formation of fusion proteins, CBFB-MYH11 and AML1-ETO, respectively, that involve members of the...

journal_title：Journal of cellular biochemistry

authors： Hyde RK,Liu PP

更新日期：2010-08-01 00:00:00

abstract：:APC and PTEN are tumor suppressor proteins that bind through their C-termini to the PDZ domain containing-hDlg scaffolding protein. We have found that co-expression of PTEN and hDlg enhanced the negative regulation of the PI3K/Akt pathway by PTEN, indicating the physiologic importance of these interactions. APC and PT...

journal_title：Journal of cellular biochemistry

authors： Sotelo NS,Valiente M,Gil A,Pulido R

更新日期：2012-08-01 00:00:00

abstract：:Large osteoclasts (>or=10 nuclei) predominate at sites of pathological bone resorption. We hypothesized this was related to increased resorptive activity of large osteoclasts and have demonstrated previously that larger osteoclasts are 8-fold more likely to be resorbing than small osteoclasts (2-5 nuclei). Here we ask...

journal_title：Journal of cellular biochemistry

authors： Trebec DP,Chandra D,Gramoun A,Li K,Heersche JN,Manolson MF

更新日期：2007-05-01 00:00:00

abstract：:Primary chicken mesenchymal cells from limb buds and vertebral chondrocytes have been used to study the changes that occur in alternative mRNA splicing of fibronectin exon EIIIA during chondrogenesis. The mesenchymal cell phenotype (exon EIIIA included) and chondrocyte phenotype (exon EIIIA excluded) were preserved in...

journal_title：Journal of cellular biochemistry

authors： Uporova TM,Norton PA,Tuan RS,Bennett VD

更新日期：1999-12-01 00:00:00

abstract：:The BRCA1 tumor suppressor involved in breast and ovarian cancer is linked to several fundamental cell regulatory processes. Recently, it was reported that BRCA1 supports localization of XIST RNA to the inactive X chromosome (Xi) in women. The apparent cytological overlap between BRCA1 and XIST RNA across the Xi raise...

journal_title：Journal of cellular biochemistry

authors： Pageau GJ,Hall LL,Lawrence JB

更新日期：2007-03-01 00:00:00

abstract：:Selected clones of Syrian hamster DDT1-MF2 cells are responsive to testosterone for growth. Heparin binding growth factor 1 (HBGF-1) or acidic fibroblast growth factor (aFGF) can replace testosterone (T) in the stimulation of growth in these cells. This phenomena is correlated with testosterone's ability to elevate aF...

journal_title：Journal of cellular biochemistry

authors： Hall JA,Harris MA,Intres R,Harris SE

更新日期：1993-01-01 00:00:00

abstract：:This study aims to investigate the combined effects of Pulsed wave low-level laser therapy (PW LLLT) and human bone marrow mesenchymal stem cell-conditioned medium (hBM-MSC-CM) on the microbial flora and tensiometrical properties of an infected wound model with methicillin-resistant staphylococcal aureus (MRSA) in an ...

journal_title：Journal of cellular biochemistry

authors： Kouhkheil R,Fridoni M,Piryaei A,Taheri S,Chirani AS,Anarkooli IJ,Nejatbakhsh R,Shafikhani S,Schuger LA,Reddy VB,Ghoreishi SK,Jalalifirouzkouhi R,Chien S,Bayat M

更新日期：2018-07-01 00:00:00

abstract：:Pristimerin is a natural product derived from the Celastraceae and Hippocrateaceae families that were used as folk medicines for anti inflammation in ancient times. Although it has been shown that pristimerin induces apoptosis in breast cancer cells, the involved mechanism of action is unknown. The purpose of the curr...

journal_title：Journal of cellular biochemistry

authors： Yang H,Landis-Piwowar KR,Lu D,Yuan P,Li L,Reddy GP,Yuan X,Dou QP

更新日期：2008-01-01 00:00:00

abstract：:Regulation of cytoplasmic free calcium concentration [Ca(2+)]i is a key factor for the maintenance of cellular homeostasis in different cell types, including lymphocytes. During T lymphocyte activation as well as production of cytokines, sustained Ca(2+) influx is essential, however, it remains unclear how this influx...

journal_title：Journal of cellular biochemistry

authors： Tomilin VN,Cherezova AL,Negulyaev YA,Semenova SB

更新日期：2016-01-01 00:00:00

abstract：:Diacylglycerol (DG) kinase (DGK), which phosphorylates DG to generate phosphatidic acid (PA), consists of ten isozymes (α-к). Recently, we identified a novel small molecule inhibitor, CU-3, that selectively inhibits the activity of the α isozyme. In addition, we newly obtained Compound A, which selectively and strongl...

journal_title：Journal of cellular biochemistry

authors： Yamaki A,Akiyama R,Murakami C,Takao S,Murakami Y,Mizuno S,Takahashi D,Kado S,Taketomi A,Shirai Y,Goto K,Sakane F

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Curcuminoids are polyphenols with documented anti-inflammatory activity and has been shown to improve the symptoms of several inflammatory diseases. We aimed to evaluate the effectiveness of a nanoformulation of curcuminoids in the treatment of ulcerative colitis. METHODS:This randomized double-blinded cont...

journal_title：Journal of cellular biochemistry

authors： Masoodi M,Mahdiabadi MA,Mokhtare M,Agah S,Kashani AHF,Rezadoost AM,Sabzikarian M,Talebi A,Sahebkar A

更新日期：2018-11-01 00:00:00

abstract：:Cleft palate is one of the most common birth defects. Several environment factors are involved in the disorder, such as smoking, vitamin deficiency and teratogens. We investigated the teratogenic agent phenytoin and extract of the immunostimulant Echinacea purpurea in the etiology of cleft palate associated with the p...

journal_title：Journal of cellular biochemistry

authors： Hu X,Chen Z,Mao X,Tang S

更新日期：2011-05-01 00:00:00

abstract：:We have partially purified and characterized an 87 kDa gelatinase activity expressed in later stage sea urchin embryos. Cleavage activity was specific for gelatin and no cleavage of sea urchin peristome type I collagen, bovine serum albumin or casein was detected. Magnesium and Zn2+ inhibited the gelatinase and Ca2+ p...

journal_title：Journal of cellular biochemistry

authors： Robinson JJ

更新日期：1997-09-01 00:00:00

abstract：:Transcription factor Sp-1 is an important fibrogenic factor that is involved in the pathogenesis of diabetic nephropathy. In this study, we examined the effect of Sp1 decoy oligodeoxynucleotides (ODNs) on the extracellular matrix (ECM) gene expression in cultured rat mesangial cells (RMC) and streptozotocin (STZ)-indu...

journal_title：Journal of cellular biochemistry

authors： Kang JH,Chae YM,Park KK,Kim CH,Lee IS,Chang YC

更新日期：2008-02-01 00:00:00