Adsorption of glycosaminoglycans to the cell surface is responsible for cellular donnan effects.

abstract：:Membrane type 1 matrix metalloproteinase (MT1-MMP, MMP14) is an efficient extracellular matrix (ECM) degrading enzyme that plays important roles in tissue homeostasis and cell invasion. Like a number of type I membrane proteins, MT1-MMP can be internalized from the cell surface through early and recycling endosomes to...

journal_title：Journal of cellular biochemistry

authors： Hakulinen J,Sankkila L,Sugiyama N,Lehti K,Keski-Oja J

更新日期：2008-12-01 00:00:00

abstract：:1alpha,25-dihydroxyvitamin D(3) (1alpha,25(OH)(2)D(3)), the active metabolite of vitamin D, mediates many of its effects through the intranuclear vitamin D receptor (VDR, NR1I1), that belongs to the large superfamily of nuclear receptors. Vitamin D receptor can directly regulate gene expression by binding to vitamin D...

journal_title：Journal of cellular biochemistry

authors： Harant H,Spinner D,Reddy GS,Lindley IJ

更新日期：2000-04-01 00:00:00

abstract：:Insects can effectively and rapidly clear microbial infections by a variety of innate immune responses including the production of antimicrobial peptides. Induction of these antimicrobial peptides in Drosophila has been well established to involve NF-kappaB elements. We present evidence here for a molecular mechanism ...

journal_title：Journal of cellular biochemistry

authors： Cornwell WD,Kirkpatrick RB

更新日期：2001-04-02 00:00:00

abstract：:The human undifferentiated histiocytic cell-line U937 can be induced to differentiate by incubation with 12-0-tetradecanoylphorbol-13-acetate (TPA) into macrophage-like cells. Dexamethasone reduced the prostaglandin production in TPA-differentiated U937 cells dose dependently, whereas undifferentiated U937 cells were ...

journal_title：Journal of cellular biochemistry

authors： Koehler L,Hass R,Goppelt-Struebe M,Kaever V,Resch K

更新日期：1989-07-01 00:00:00

abstract：:Saitohin (STH) is a gene unique to humans and their closest relatives whose function is not yet known. STH contains a single polymorphism (Q7R); the Q allele is human-specific and confers susceptibility to several neurodegenerative diseases. In previous work, we discovered that STH interacts with Peroxiredoxin 6 (Prdx...

journal_title：Journal of cellular biochemistry

authors： Wang Y,Gao L,Conrad CG,Andreadis A

更新日期：2011-11-01 00:00:00

abstract：:Connexin43 (Cx43) is a ubiquitously expressed member of the gap junction protein family that mediates gap junction intercellular communication (GJIC) by allowing exchange of cytosolic materials. Previous studies have used Cx43 truncated at the cytoplasmic tail (C-tail) to demonstrate that the C-tail is essential to re...

journal_title：Journal of cellular biochemistry

authors： Crespin S,Bechberger J,Mesnil M,Naus CC,Sin WC

更新日期：2010-06-01 00:00:00

abstract：:Long-term treatment with heparin has been associated with an increased risk of osteoporosis. Given the importance of heparan sulfate proteoglycans for bone metabolism, it can be anticipated that heparin due to its structural similarity with heparan sulfate chains somehow interferes with the biological activities of th...

journal_title：Journal of cellular biochemistry

authors： Hausser HJ,Brenner RE

更新日期：2004-04-01 00:00:00

abstract：:Evidence is presented for the first time that the cytochrome P450XVII-catalysed androgen formation from progesterone (P) in rat testicular microsomal membranes represents a metabolic sequence that exhibits the ability of intrinsic regulation of intermediate transfer and product formation efficiency. Exposure of this s...

journal_title：Journal of cellular biochemistry

authors： Kühn-Velten WN

更新日期：1990-06-01 00:00:00

abstract：:Gastric cancer (GC) is the second most common cause of cancer death worldwide but could be more curable if diagnosed at an earlier stage. At present, the capability to predict the efficaciousness of molecular diagnosis for GC for each patient remains elusive. The purpose of this study was to identify tumor biomarkers ...

journal_title：Journal of cellular biochemistry

authors： Ai K,Jia Y,Li J,Wang C,Wang Y

更新日期：2018-11-13 00:00:00

abstract：:In our previous study, preliminary data indicates that Poria cocos polysaccharides (PCP) shows beneficial hepatoprotection against acetaminophen (APAP)-induced liver injury in mice. However, biological molecular mechanism warrants to be further discussed. In current study, a number of biochemical tests and immunoassay...

journal_title：Journal of cellular biochemistry

authors： Wu K,Guo C,Yang B,Wu X,Wang W

更新日期：2019-05-01 00:00:00

abstract：:Prostaglandin E2 (PGE2) is one of pro-inflammatory mediators. PGE2 maintains the homeostasis of many organs including articular cartilage, and a previous report showed that continuous inhibition of PGE2 accelerates the progression of osteoarthritis (OA). While PGE2 inhibits matrix metalloprotease (MMP) expression in s...

journal_title：Journal of cellular biochemistry

authors： Nishitani K,Ito H,Hiramitsu T,Tsutsumi R,Tanida S,Kitaori T,Yoshitomi H,Kobayashi M,Nakamura T

更新日期：2010-02-01 00:00:00

abstract：:As an important tumor suppressor, programmed cell death 4 (PDCD4) influences transcription and translation of multiple genes, and modulates different signal transduction pathways. However, the upstream regulation of this gene is largely unknown. In this study, we found that microRNA-182 (miRNA-182, miR-182) was upregu...

journal_title：Journal of cellular biochemistry

authors： Wang YQ,Guo RD,Guo RM,Sheng W,Yin LR

更新日期：2013-07-01 00:00:00

abstract：:A key step in human colon cancer development includes the hyperactivation of Wnt/beta-catenin signaling and the induction of beta-catenin-TCF target genes that participate in colon cancer progression. Recent studies identified members of the immunoglobulin-like cell adhesion molecules (IgCAM) of the L1CAM family (L1 a...

journal_title：Journal of cellular biochemistry

authors： Raveh S,Gavert N,Spiegel I,Ben-Ze'ev A

更新日期：2009-09-01 00:00:00

abstract：:Calcium-dependent cell adhesion molecules (CAMs) mediate intercellular adhesion in epithelial cells and in preimplantation mammalian embryos. One of these molecules, cell-CAM 120/80, is found on cells as a 120-kd membrane glycoprotein and as a soluble 80-kd species in conditioned culture medium [Damsky et al: Cell 34:...

journal_title：Journal of cellular biochemistry

authors： Wheelock MJ,Buck CA,Bechtol KB,Damsky CH

更新日期：1987-07-01 00:00:00

abstract：:Integrins are heterodimeric transmembrane cellular receptors that link the cell to its underlying substratum. Alterations in integrin expression and signaling have been implicated in many aspects of tumorigenesis and metastasis including cell survival, migration, and invasion. In prostate cancer, the progression from ...

journal_title：Journal of cellular biochemistry

authors： Slack-Davis JK,Parsons JT

更新日期：2004-01-01 00:00:00

abstract：:Esophageal carcinoma is aggressive in nature and its prognosis is largely dependent on the degree of invasion. Histone deacetylase 6 (HDAC6), as the most unique member of HDACs family, has the positive activity to promote initiation and progression of various cancers via targeting multiple non-histone proteins in cyto...

journal_title：Journal of cellular biochemistry

authors： Tao H,Chen YY,Sun ZW,Chen HL,Chen M

更新日期：2018-08-01 00:00:00

abstract：:Previous studies have demonstrated that germ cells can be derived from mouse embryonic stem cells (ESCs). However, there is still no efficient system, which can visualize the stage of germ cell specification in vitro, and further to identify and enrich germ cells derived from ESCs. Figla (factor in the germline, alpha...

journal_title：Journal of cellular biochemistry

authors： Hu Y,Sun J,Wang J,Wang L,Bai Y,Yu M,Lian Z,Zhang S,Hua J

更新日期：2012-04-01 00:00:00

abstract：:We have analyzed the distribution of type II collagen N- and C-propeptides in the cell layers and culture medium of bovine articular chondrocyte pellet cultures. Two splice variants of the type II collagen N-propeptide were detected by immunoblotting and immunoassay, using a new anti-peptide antibody, while the C-prop...

journal_title：Journal of cellular biochemistry

authors： Rebuck N,Croucher LJ,Hollander AP

更新日期：1999-10-01 00:00:00

abstract：:This study investigates the effect of nuclear factor erythroid 2-related factor 2-antioxidant response element (Nrf2-ARE) signaling pathway in vascular calcification (VC) via inducing Autophagy in renal vascular smooth muscle cells (VSMCs). VSMCs were assigned into six experimental groups: the normal control, high pho...

journal_title：Journal of cellular biochemistry

authors： Yao L,Wang J,Tian BY,Xu TH,Sheng ZT

更新日期：2017-12-01 00:00:00

abstract：:Selected clones of Syrian hamster DDT1-MF2 cells are responsive to testosterone for growth. Heparin binding growth factor 1 (HBGF-1) or acidic fibroblast growth factor (aFGF) can replace testosterone (T) in the stimulation of growth in these cells. This phenomena is correlated with testosterone's ability to elevate aF...

journal_title：Journal of cellular biochemistry

authors： Hall JA,Harris MA,Intres R,Harris SE

更新日期：1993-01-01 00:00:00

abstract：:microRNA (miRNA) is a family of small, non-coding RNA first discovered as an important regulator of development in Caenorhabditis elegans (C. elegans). Numerous miRNAs have been found in C. elegans, and some of them are well conserved in many organisms. Though, the biologic function of miRNAs in C. elegans was largely...

journal_title：Journal of cellular biochemistry

authors： Liu J,Yang B,Ai J

更新日期：2013-05-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) have been used in therapies for bone tissue healing. The aim of this study was to investigate the effect of cell source and osteoblast differentiation on gene expression profiles of MSCs from bone marrow (BM-MSCs) or adipose tissue (AT-MSCs) to contribute for selecting a suitable cell pop...

journal_title：Journal of cellular biochemistry

authors： Fideles SOM,Ortiz AC,Assis AF,Duarte MJ,Oliveira FS,Passos GA,Beloti MM,Rosa AL

更新日期：2019-02-11 00:00:00

abstract：:Male germline stem cells (mGSCs), in charge for the fertility in male testis, are the only kind of adult stem cells that transmit genetic information to next generation, with promising prospects in germplasm resources preservation and optimization, and production of transgenic animals. Mouse male germline stem cell li...

journal_title：Journal of cellular biochemistry

authors： Zhu H,Ma J,Du R,Zheng L,Wu J,Song W,Niu Z,He X,Du E,Zhao S,Hua J

更新日期：2014-09-01 00:00:00

abstract：:Endometrial carcinoma (EC) is one of the main gynecologic malignancies affecting women, but effective treatments are currently lacking. In the present study, we investigated the effect of sorafenib, a general kinase inhibitor, on several EC cell lines (HEC1A, HEC1B, and RL95-2). Sorafenib induced cell death in EC cell...

journal_title：Journal of cellular biochemistry

authors： Sun NK,Huang SL,Chang TC,Chao CC

更新日期：2013-08-01 00:00:00

abstract：:The mitogen regulated protein/proliferin (MRP/PLF) gene is transcribed in primary mouse embryo fibroblasts (MEFs), but the pre-mRNA is not properly converted into a stable cytoplasmic mRNA and instead is rapidly degraded, apparently in the nucleus [Malyankar et al. (1994): Proc Natl Acad Sci USA 91:335-359]. In 3T3 ce...

journal_title：Journal of cellular biochemistry

authors： Malyankar UM,Rittling SR,Denhardt DT

更新日期：1996-02-01 00:00:00

abstract：PURPOSE:The relationship between inflammatory markers and energetic metabolism has been explored. However, the relationship between exercise intensity and fitness status is unclear, and it is necessary to understand this relationship to apply specific exercise guidance. The purpose of the study was to analyze metabolic...

journal_title：Journal of cellular biochemistry

authors： Antunes BM,Campos EZ,Dos Santos RVT,Rosa-Neto JC,Franchini E,Bishop NC,Lira FS

更新日期：2019-04-01 00:00:00

abstract：:A variant human H2B histone gene (GL105), previously shown to encode a 2300 nt replication independent mRNA, has been cloned. We demonstrate this gene expresses alternative mRNAs regulated differentially during the HeLa S3 cell cycle. The H2B-Gl105 gene encodes both a 500 nt cell cycle dependent mRNA and a 2300 nt con...

journal_title：Journal of cellular biochemistry

authors： Collart D,Romain PL,Huebner K,Pockwinse S,Pilapil S,Cannizzaro LA,Lian JB,Croce CM,Stein JL,Stein GS

更新日期：1992-12-01 00:00:00

abstract：:Annexin II is a multifunctional calcium-dependent phospholipid binding protein whose presence in epidermis has previously been reported. However, like other members of annexin family, annexin II has been regarded as either an intracellular protein or associated with the cellular membrane. Here, we report the presence ...

journal_title：Journal of cellular biochemistry

authors： Karimi-Busheri F,Marcoux Y,Tredget EE,Li L,Zheng J,Ghoreishi M,Weinfeld M,Ghahary A

更新日期：2002-01-01 00:00:00

abstract：:Adipose tissue is critical in obesity and type II diabetes. Blocking of adipocyte differentiation is one of the anti-obesity strategies targeting on strong rise in fat storage and secretion of adipokine(s). However, the molecular basis of adipocyte differentiation and its regulation remains obscure. Therefore, we expo...

journal_title：Journal of cellular biochemistry

authors： Ye F,Zhang H,Yang YX,Hu HD,Sze SK,Meng W,Qian J,Ren H,Yang BL,Luo MY,Wu X,Zhu W,Cai WJ,Tong JB

更新日期：2011-10-01 00:00:00

abstract：:Four detergents have been compared for identification of the Plasmodium knowlesi variant antigen on infected erythrocytes by immunoprecipitation analysis. Erythrocytes infected with late trophozoite and schizont forms of cloned asexual parasites were labeled by lactoperoxidase-catalyzed radioiodination and extracted e...

journal_title：Journal of cellular biochemistry

authors： Howard RJ,Barnwell JW

更新日期：1984-01-01 00:00:00