Abstract:
:A patient with thioridazine-hydrochloride-associated agranulocytosis is described and eight previously reported cases are reviewed. This complication is most likely due to a direct toxic effect on the bone marrow. As in our case, markers for an immunologically mediated mechanism have not been found. Thioridazine-hydrochloride-associated agranulocytosis usually occurs between the fifth and 11th week of therapy and is not related to the total dose of drug received. Three of the nine patients with thioridazine-hydrochloride-associated agranulocytosis have died from infectious complications. Thus, careful monitoring for infection and prompt therapy are indicated.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Ferguson RL,Hodges GR,Bogner PJdoi
10.1097/00007611-197701000-00051subject
Has Abstractpub_date
1977-01-01 00:00:00pages
110-1issue
1eissn
0038-4348issn
1541-8243journal_volume
70pub_type
杂志文章abstract::A case of perforation and bleeding from a diverticulum of the second portion of the duodenum in a patient with recurrent pancreatitis is presented. Upper gastrointestinal roentgenogram revealed an abnormal tract and retroperitoneal air arising from the diverticulum. The fistulous tract communicated with pancreas. Blee...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197706000-00037
更新日期:1977-06-01 00:00:00
abstract::Although d-penicillamine has a wide range of benefits in many clinical conditions, various side effects have also been reported and preclude its further use in certain patients. In this case, d-penicillamine-induced reversible airway obstruction developed, despite the "go slow--go low" regimen as suggested to reduce t...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198006000-00032
更新日期:1980-06-01 00:00:00
abstract::AIDS-related Kaposi's sarcoma rarely involves bone or bone marrow. Computed tomography of the abdomen and pelvis of an AIDS patient with lower back pain and bilateral limb edema revealed multiple lesions involving liver, spleen, and axial skeleton. Bone marrow examination of the involved iliac crest revealed Kaposi's ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199901000-00012
更新日期:1999-01-01 00:00:00
abstract::Though low, the incidence of malaria in the United States is not insignificant and can be the source of infection in febrile travelers returning from endemic areas. Clinicians practicing in the United States must have a basic understanding of the malaria life cycle and its treatments to properly diagnose and treat thi...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.smj.0000189904.50838.eb
更新日期:2005-12-01 00:00:00
abstract::Only in relatively recent years has the role of dietary fiber, once thought to be an unnecessary and even undesirable by-product, begun to be appreciated in the maintenance of health. Research now indicates that a deficiency of fiber in the modern western diet may contribute to a host of diseases. Inadequate dietary f...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198610000-00003
更新日期:1986-10-01 00:00:00
abstract:OBJECTIVE:This study aimed to identify differences in perceptions between healthcare and non-healthcare personnel when it comes to wearing scrubs in non-healthcare settings. METHODS:An anonymous survey with 11 closed-ended questions sent via e-mail to healthcare students and employees at The University of Texas Health...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000861
更新日期:2018-09-01 00:00:00
abstract::From 1976 to 1982, 12 children with myelodysplasia had surgery at our institution for knee flexion contractures (21 affected knees). Follow-up was a minimum of 18 months and averaged 47 months. Soft tissue lengthening of the hamstring tendons and release of the posterior capsule with or without femoral osteotomy yield...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198607000-00009
更新日期:1986-07-01 00:00:00
abstract::While opioids are regarded as the mainstay of chronic pain management, their use is controversial in the minds of many primary care physicians due to clinical concerns about dependence, abuse, and addiction and medicolegal concerns regarding state and federal regulatory authorities. For patients with moderate to moder...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e3180f626ff
更新日期:2007-10-01 00:00:00
abstract::In a ten-year period 139 patients with epidermoid carcinoma of the esophagus were treated by palliative feeding procedures, palliative radiation therapy, radiation therapy for cure, or resection. Analysis of the results of these modes of therapy indicates that long-term palliation is best achieved when resection is th...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197606000-00016
更新日期:1976-06-01 00:00:00
abstract::We report a retrospective evaluation of the role of panretinal photocoagulation in the primary treatment of neovascular glaucoma. Thirty-six eyes (32 patients) received aggressive argon laser panretinal photocoagulation beginning as soon as feasible after diagnosis of the developing neovascular glaucoma. Thirty eyes w...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198811000-00008
更新日期:1988-11-01 00:00:00
abstract::Most nonendocrine pancreatic neoplasms are adenocarcinomas of ductal cell or acinar origin. Primary carcinomas of the pancreas with squamous differentiation are rare enough to warrant a search for other primary tumors. In the past few decades, well-documented individual reports and large series reviews support the vie...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-08-01 00:00:00
abstract::In El Paso County, Texas, 73 domestic wells were sampled using a variety of selective media to determine the extent of bacterial contamination of the groundwater on the US side of the United States-Mexico border. Thirteen wells were contaminated by fecal coliforms, whereas other wells contained a variety of bacterial ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199412000-00004
更新日期:1994-12-01 00:00:00
abstract::We retrospectively reviewed 20 surgically confirmed tubo-ovarian abscesses in postmenopausal women for the period 1973 to 1989. Pain and bleeding were the two most common presenting symptoms. Nine of the 20 patients (45%) had recently had endometrial instrumentation. Fever and the presence of a pelvic mass and elevate...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199207000-00006
更新日期:1992-07-01 00:00:00
abstract::This paper briefly reviews the available evidence for the influence of environmental and occupational factors in the development of cancer of the larynx. Although several occupational exposures have been suggested to play a role in the etiology of this disease, few have been convincingly confirmed. The strong associat...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198307000-00020
更新日期:1983-07-01 00:00:00
abstract::Reviewed are 200 cases in which endolaryngeal suspension microsurgical procedures were done using intravenous anesthesia and Venturi insufflation oxygenation. Patients included 177 adults and 23 children, ranging in age from 20 months to 88 years. No significant complications were observed. The technic allowed the glo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197607000-00003
更新日期:1976-07-01 00:00:00
abstract::We describe the case of a patient with acquired immunodeficiency syndrome (AIDS) who had a CD4 cell count of 60/microL, bilateral hilar adenopathy, and hypercalcemia. Transbronchial biopsy showed T-cell anaplastic large cell lymphoma. Serology was negative for human T-cell leukemia virus-I (HTLV-I). This appears to be...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract::Use of the needle-catheter feeding jejunostomy at Richland Memorial Hospital and the Dorn Veterans Administration Hospital, both clinical teaching institutions of the University of South Carolina School of Medicine, has been evaluated in 114 patients ranging from 20 to 90 years old. The results of this survey span a 3...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198611000-00018
更新日期:1986-11-01 00:00:00
abstract::Preeclampsia has been frequently misdiagnosed as an entity unrelated to pregnancy, with resultant delay in appropriate management. In the case presented here, severe preeclampsia complicated by hemolysis, elevated liver enzymes, and low platelet count ("HELLP syndrome") in a 32-week twin gestation was misdiagnosed as ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199411000-00026
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:Surveys in recent years show that office emergencies are likely to occur in pediatric offices and that most offices are not equipped to deal with these situations. METHODS:To determine the pediatrician's preparedness to manage emergencies, we surveyed a randomly selected sample of 240 office-based pediatric...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199808000-00008
更新日期:1998-08-01 00:00:00
abstract::Cobalamin (vitamin B12) deficiency warrants appropriate evaluation because cobalamin is necessary in certain biochemical functions. R-binder deficiency, which causes low cobalamin levels, is a rare and benign pseudodeficiency. If not further evaluated by determining levels of methylmalonic acid and homocysteine, howev...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract::Considerable controversy exists with regard to therapeutic efficacy of plasmapheresis in the immune-mediated demyelinating disorders of the peripheral and central nervous system: acute inflammatory polyneuropathy (Guillain-Barré syndrome), chronic inflammatory demyelinating polyneuropathy, and multiple sclerosis. In a...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198608000-00018
更新日期:1986-08-01 00:00:00
abstract::We have described a patient with strangulation of a Meckel's diverticulum in a femoral hernia. In the case of Littre's hernia, true diagnosis before surgical intervention is rare if not impossible. It is therefore important that the surgeon be well versed in the management of such cases, as well as in distinguishing a...
journal_title:Southern medical journal
pub_type: 历史文章,杂志文章
doi:10.1097/00007611-198705000-00027
更新日期:1987-05-01 00:00:00
abstract::Seventeen patients with Crohn's disease requiring emergency operative procedures disclosed important factors leading to successful outcome. In seven of the ten patients not known to have Crohn's disease, the history strongly suggested this diagnosis. Two patients died; three others had major complications, including t...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197810000-00010
更新日期:1978-10-01 00:00:00
abstract::Insomnia disorder is present in as much as 30% of the general adult population. Given the significant adverse effects of pharmacotherapy, cognitive behavioral therapy (CBT) has been found to be an effective alternative in individuals with insomnia. CBT for insomnia (CBTi) encompasses sleep hygiene, stimulus control, s...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.14423/SMJ.0000000000000769
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVES:Hematological malignancies of the breast share a presentation similar to primary breast carcinomas but differ substantially in therapeutic approach and clinical outcomes. In this study, we investigate the frequency of hematological malignancies, their relative primary and secondary occurrences, and further c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000710
更新日期:2017-10-01 00:00:00
abstract::Elderly patients with community-acquired pneumonia may not have a systemic inflammatory response characterized by fever and leukocytosis. We compared lack of fever and leukocytosis with mortality in elderly patients with community-acquired pneumonia. Patients with fever and leukocytosis (group A, 47 patients) were com...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199703000-00006
更新日期:1997-03-01 00:00:00
abstract::Reported is the association of condyloma acuminatum and squamous carcinoma of the vulva in three cases and condyloma followed by squamous dysplasia in a fourth case. This association has previously been reported in both male and female genitalia and in the perianal area. In our four cases, cancer or squamous dysplasia...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197705000-00029
更新日期:1977-05-01 00:00:00
abstract::This case presents a rare type of crescentic glomerulonephritis characterized as IgA deposits predominantly along the glomerular basement membranes (GBM). The patient clinically manifested with rapidly progressive glomerulonephritis (RPGN) without pulmonary hemorrhage or vasculitis-related systematic symptoms. No posi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181817c22
更新日期:2008-09-01 00:00:00
abstract::Patients treated with ventriculoperitoneal (VP) shunt procedures for hydrocephalus may have abdominal pain related to complications stemming from the shunt tubing itself or to other intra-abdominal disease. In patients with VP shunts, usually children, lack of absorption of cerebrospinal fluid (CSF) may produce a pain...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199208000-00014
更新日期:1992-08-01 00:00:00
abstract::The association of hypercoagulation and cancer, a well established pattern of disease, often leads to pulmonary emboli in an already compromised patient. Anticoagulation therapy in these patients is occasionally complicated by several factors including thrombocytopenia, which may result in a life-threatening situation...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:
更新日期:1987-10-01 00:00:00