Abstract：
:Although the mortality rate after herpes simplex virus type 2 inoculation was not significantly different between pregnant mice and nonpregnant mice, systemic interferon production was very high during late pregnancy compared with that in nonpregnant mice. Antiviral activity was detected in placentas from all noninfected pregnant mice (80 to 320 U/ml in 20% suspension). The antiviral activity had a broad spectrum and was also effective in the cells of other species; an antiviral effect was shown even if the cells were treated after challenge with a virus. In addition, this activity was not inactivated by antimouse interferon-neutralizing antisera. The molecular weight of this placental antiviral substance was estimated to be 200,000 to 450,000 daltons by gel filtration, and it was inactivated by heat, acid, and trypsin. Noninterferon antiviral activity (40 to 80 U/ml) was also detected in more than half the sera (61.5%) of noninfected mice in late pregnancy.
journal_name
Am J Obstet Gynecoljournal_title
American journal of obstetrics and gynecologyauthors
Yamada K,Shimizu Y,Okamura K,Kumagai K,Suzuki Mdoi
10.1016/s0002-9378(85)80127-7subject
Has Abstractpub_date
1985-10-01 00:00:00pages
335-41issue
3eissn
0002-9378issn
1097-6868pii
S0002-9378(85)80127-7journal_volume
153pub_type
杂志文章abstract：OBJECTIVE:Amniotic fluid embolism syndrome is a fatal disease in pregnant women. The exact role of platelets and neutrophils in amniotic fluid embolism syndrome is not clear. We examined whether amniotic fluid could affect platelet-neutrophil aggregation and activation and the possible mechanisms. STUDY DESIGN:Blood s...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2013.01.012
更新日期：2013-04-01 00:00:00
abstract：:The purpose of our study was to develop new biologic systems for the treatment or diagnosis of patients with ovarian carcinoma through expansion of T-cell lines from the tumor-infiltrating lymphocytes of patients with ovarian carcinoma in low-dose recombinant interleukin-2 in sufficient numbers for treatment and human...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/s0002-9378(11)91735-9
更新日期：1992-11-01 00:00:00
abstract：:Nuchal cords can be diagnosed prenatally with ultrasonographic imaging. A prospective study determined the timing of nuchal cord formation and, in some cases, resolution before delivery. ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(95)90337-2
更新日期：1995-09-01 00:00:00
abstract：BACKGROUND:A growing literature suggests that minority races, particularly Black women, have a lower probability of live birth and higher risk of perinatal complications after autologous assisted reproductive technology. However, questions still remain as to whether these racial disparities have arisen because of assoc...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2020.09.013
更新日期：2020-09-12 00:00:00
abstract：OBJECTIVE:The purpose of this study was to evaluate the effect of preterm premature rupture of the membranes on the frequency of respiratory distress syndrome among singleton pregnancies that are complicated with preterm delivery. STUDY DESIGN:We performed a retrospective analysis of singleton pregnancies that were de...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2002.126203
更新日期：2002-08-01 00:00:00
abstract：OBJECTIVE:To determine maternal and perinatal outcome in women with severe preeclampsia at <26 weeks according to gestational age at the onset of expectant management and the presence of severe fetal growth restriction (<5th percentile). STUDY DESIGN:Fifty-one patients (53 fetuses; 2 twins) were retrospectively studie...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2011.06.062
更新日期：2011-11-01 00:00:00
abstract：OBJECTIVE:We performed a systematic review to evaluate endovaginal cervical ultrasonography as a predictor of preterm delivery. STUDY DESIGN:Selection criteria were original published English-language reports of prospective studies including women at <37 weeks' gestation with intact amniotic membranes. Parameters and ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/s0002-9378(99)70407-2
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine the inhibitory effects of anti-interleukin-1beta and transforming growth factor-beta2 on the production of interleukin-1beta and prostaglandin E2 by human decidual cells. STUDY DESIGN:Decidual membranes were obtained from 30 patients between 37 and 40 weeks' gestati...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章
doi：10.1016/s0002-9378(98)70265-0
更新日期：1998-07-01 00:00:00
abstract：:Brachial artery Doppler flow velocity waveforms were recorded from 10 nonpregnant women and 19 women with uncomplicated pregnancies. The pregnant group showed higher peak systolic frequencies (3.24 compared with 2.26, p = 0.01), higher maximum end-diastolic frequencies (0.62 compared with 0.25, p = 0.01), and lower pu...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(91)90026-n
更新日期：1991-12-01 00:00:00
abstract：:A 3-year follow-up study was carried out on 20 children examined in utero with echo-planar magnetic resonance imaging when fetal compromise had been demonstrated or was suspected. There was no demonstrable increase in the occurrence of disease or disability (including hearing deficit) that could be related to echo-pla...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(94)70379-5
更新日期：1994-01-01 00:00:00
abstract：:Prolactin production by decidualized human endometrium has been demonstrated in organ explant cultures and presumed to be of stromal origin by immunocytochemistry and the presence of simultaneous stromal histologic changes. To test the hypothesis that endometrial prolactin production is exclusively of stromal origin, ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(90)91325-7
更新日期：1990-04-01 00:00:00
abstract：:We describe the first pregnancy in a homozygous familial hypercholesterolemic woman who started plasma exchange therapy 3 years before she became pregnant. We especially studied the effects of plasma exchange on lipid profile, uteroplacental circulation, and pregnancy course. ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(90)90824-q
更新日期：1990-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this report is to bring to the attention of obstetric care providers the occurrence in pregnancy of a threatening pulmonary syndrome caused by hantavirus infection. STUDY DESIGN:Two recent cases of hantavirus pneumonitis in pregnancy, one complicated by adult respiratory distress syndrome, are...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(94)90298-4
更新日期：1994-08-01 00:00:00
abstract：:Umbilical cord abnormalities can be observed with ultrasonography. Two cases are described where a triple knot and torsion of the umbilical cord are observed. These cases allow the elucidation of the mechanics of formation of a triknot and torsion abnormality. ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(93)90139-a
更新日期：1993-07-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to estimate the association of parity with pelvic girdle syndrome (PGS; pain in anterior and bilateral posterior pelvis). STUDY DESIGN:We included 75,939 pregnant women in the Norwegian Mother and Child Cohort Study. Data were obtained by self-administered questionnaires. RESUL...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2010.03.040
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to identify differences in antepartum uterine contraction frequency (UCF) in twin pregnancies with and without preterm labor (PTL). STUDY DESIGN:Twin gestations enrolled for outpatient surveillance with twice daily electronic uterine activity monitoring and telephonic nursing as...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2007.10.781
更新日期：2008-05-01 00:00:00
abstract：OBJECTIVE:High-risk antepartum patients often require long and costly hospitalization. The Mother's House facility has been used to house antepartum women on hospital property as an alternative to inpatient management. This study looked at the cost effectiveness of this facility. STUDY DESIGN:A retrospective chart rev...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2007.04.045
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:Age-related decline in reproductive potential is mainly due to the increased incidence of aneuploidy. Furthermore, 2 recent studies have shown that euploid embryos of older women may have a lower implantation potential compared to those of younger women, suggesting that aging might compromise embryos beyond ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2018.11.1103
更新日期：2019-04-01 00:00:00
abstract：:The diagnosis of polycystic ovary syndrome (PCOS) is primarily achieved through clinical history and physical findings. The principle features are hirsutism or biochemical evidence of excess androgen production and irregular menstrual bleeding caused by the chronic anovulation. Associated findings include insulin resi...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.ajog.2004.04.045
更新日期：2004-09-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to determine whether hysteroscopy improves the detection and extraction of endometrial polyps in postmenopausal women. This method was compared with curettage complemented by Randall polyp forceps. STUDY DESIGN:In a prospective study hysteroscopy was performed before and after curet...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2001.108332
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVES:In utero gene therapy has a potential to correct genetic disorders before the first clinical symptoms appear. Our aim was to examine whether the exocoelomic cavity between amniotic and chorionic membranes offers a minimally invasive route for gene transfer to the fetus during early pregnancy. STUDY DESIGN:W...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2003.07.010
更新日期：2004-01-01 00:00:00
abstract：:The aim of this study was to observe the sequential effects of oxygenation, umbilical cord occlusion, and finally cooling on circulating catecholamines and nonshivering thermogenesis in fetal sheep. We studied five fetal sheep at 132 +/- 3 days' gestation. The fetuses were first ventilated with oxygen; PaO2 levels wer...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(91)90655-b
更新日期：1991-01-01 00:00:00
abstract：:The prophylactic use of oral terbutaline was studied in 28 normal, healthy, low-risk women with twin gestations. The mean birth weights were significantly increased over those in a similar group of control patients. ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(86)90481-3
更新日期：1986-04-01 00:00:00
abstract：OBJECTIVE:This study was undertaken to evaluate the attitude of anesthesiologists and gynecologists to the use of blood during cesarean section operation and, on the basis of the results, to ascertain the need for improvement of current transfusion guidelines. STUDY DESIGN:A scenario-based survey was performed. RESUL...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2003.07.028
更新日期：2004-02-01 00:00:00
abstract：OBJECTIVE:The goal of this study was to determine whether estrogen increases the expression of the inducible nitric oxide synthase gene. STUDY DESIGN:An inducible nitric oxide synthase fusion gene was created with its promoter and the reporter gene, luciferase. COS cells were transfected transiently with the fusion ge...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2003.350
更新日期：2003-05-01 00:00:00
abstract：:To determine the role of carbon dioxide in the generation of fetal respiratory movements, the effect of induced maternal hypocapnia and hypercapnia on fetal breathing movements, gross body movements, and fetal heart rate was studied in 12 healthy pregnant women near term. Patients were studied for a 1-hour control per...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0002-9378(88)90147-0
更新日期：1988-02-01 00:00:00
abstract：OBJECTIVE:Oxidative stress occurs when the production of damaging free radicals and other oxidative molecules exceeds the capacity of the body's antioxidant defenses. Oxidative stress is implicated in diseases that are associated with prematurity (such as retinopathy, cerebral palsy, intraventricular hemorrhage, and ne...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2003.357
更新日期：2003-07-01 00:00:00
abstract：OBJECTIVE:Our aim was to determine the fate of mandatory resident research projects with regard to subsequent presentation and publication. STUDY DESIGN:In this retrospective descriptive study required research projects were assessed for frequency of presentation at regional and national meetings or publication in med...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(94)70281-0
更新日期：1994-03-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to compare bodyweight and composition (percent fat, fat mass, and fat-free mass) in neonates born to mothers with a normal pregravid body mass index (BMI; < 25 kg/m(2)) vs neonates born to mothers with an overweight/obese pregravid BMI (> or = 25 kg/m(2)). STUDY DESIGN:Seventy-t...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2007.10.796
更新日期：2008-04-01 00:00:00
abstract：:Domiciliary fetal monitoring via a telephone link has been in clinical use at the Royal Free Hospital for 2 years, during which time 858 traces of 134 patients who were moderately at risk have been transmitted to the hospital. All recognized abnormal heart rate patterns were detected during the study period. In seven ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(90)90411-y
更新日期：1990-02-01 00:00:00
