Probable histamine liberation with atracurium. A case report.

Abstract:

:An histaminoid reaction after the administration of thiopentone and atracurium is described. Serial blood sampling showed no evidence of complement activation. Intradermal testing 6 weeks later yielded a positive result with atracurium (1 in 1000), but not with thiopentone. The clinical course of the reaction and the subsequent investigations suggest a direct pharmacological liberation of histamine.

journal_name

Br J Anaesth

authors

Lavery GG,Boyle MM,Mirakhur RK

doi

10.1093/bja/57.8.811

subject

Has Abstract

pub_date

1985-08-01 00:00:00

pages

811-3

issue

8

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)41354-7

journal_volume

57

pub_type

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