Squamous cell carcinomas that arise in the oral cavity and tongue base: can CT help predict perineural or vascular invasion?

Abstract:

PURPOSE:To determine the ability to use computed tomography (CT) to predict invasion of adjacent nerves or vessels by oral cavity tumors. MATERIALS AND METHODS:Contrast material-enhanced CT scans and histopathologic reports were retrospectively reviewed in 48 patients (36 men, 12 women) aged 38-75 years who underwent gross total resection of squamous cell carcinomas arising in the tongue, the base of the tongue, and the floor of the mouth. CT criteria for diagnosis of perineural or vascular invasion were aggressive tumor margins, invasion of the sublingual space, and direct adjacency of the tumor to the enhanced lingual vasculature in the sublingual space. CT and histopathologic findings of perineural and/or vascular invasion by tumor were correlated in all patients. RESULTS:With the above criteria, CT findings predictive of perineural or vascular invasion had a sensitivity of 88%; specificity, 83%; positive predictive value, 85%; and negative predictive value, 84%. CONCLUSION:CT findings can be used to predict perineural or vascular invasion by oral cavity tumors.

journal_name

Radiology

journal_title

Radiology

authors

Mukherji SK,Weeks SM,Castillo M,Yankaskas BC,Krishnan LA,Schiro S

doi

10.1148/radiology.198.1.8539370

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

157-62

issue

1

eissn

0033-8419

issn

1527-1315

journal_volume

198

pub_type

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