Abstract:
PURPOSE:To determine if comparison of in-phase and opposed-phase gradient-echo magnetic resonance (MR) images enables detection of lipid in renal clear cell carcinoma. MATERIALS AND METHODS:A retrospective search of MR and pathologic records identified 43 patients with biopsy-proved renal masses who underwent in-phase and opposed-phase MR imaging. Thirty-three patients had renal cell carcinoma (27 with clear cell carcinoma), and 10 patients had other renal tumors. With MR images, a region-of-interest measurement of signal intensity of the renal mass was divided by that of reference tissue. In each patient, a ratio of these region-of-interest measurements on the opposed-phase images to those on the in-phase images was calculated and termed the opposed-phase/in-phase signal intensity ratio (OIR). RESULTS:The mean OIR of clear cell carcinomas was significantly different from that of other renal masses (P < .0002); in 16 (59%) of 27 patients with clear cell carcinoma, the OIR was less than 2 standard deviations below the mean OIR of other masses. In cases of clear cell carcinoma, focal signal intensity on opposed-phase images was less than that on in-phase images. CONCLUSION:On opposed-phase images, some clear cell carcinomas show relative focal and diffuse loss of signal intensity. In renal masses, this signal intensity loss-which is consistent with lipid-does not necessarily indicate angiomyolipoma.
journal_name
Radiologyjournal_title
Radiologyauthors
Outwater EK,Bhatia M,Siegelman ES,Burke MA,Mitchell DGdoi
10.1148/radiology.205.1.9314970subject
Has Abstractpub_date
1997-10-01 00:00:00pages
103-7issue
1eissn
0033-8419issn
1527-1315journal_volume
205pub_type
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