Could polymerase chain reaction tests on conjunctival swabs be useful to diagnose herpetic keratitis?

Abstract:

INTRODUCTION:Diagnosis of HSV-1 keratitis (HK) is frequently based on clinical findings. Invasive specimens (corneal scrapings, biopsies) are required for microbiological diagnosis. METHODS:Corneal scrapings and conjunctival swabs were collected on patients with/without clinical suspicion of HK from 2007 to 2012. RESULTS:The sensitivity, specificity, positive and negative predictive values for conjunctival swabs by PCR was 77.8, 92.1, 84.4 and 88.3, respectively. DISCUSSION:Conjunctival swabs by PCR may help in the diagnosis of HK, despite the limited sensitivity.

authors

Barrado L,Suarez MJ,Pérez-Blázquez E,Otero JR,Folgueira MD

doi

10.1016/j.eimc.2013.07.005

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

28-30

issue

1

eissn

0213-005X

issn

1578-1852

pii

S0213-005X(13)00211-5

journal_volume

32

pub_type

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