Evaluation of antioxidant, antimutagenic, and lipid peroxidation inhibitory activities of selected fractions of Holarrhena floribunda (G. Don) leaves.

abstract：:A method has been developed for functional reconstitution of the isolated pyruvate carrier. Optimal conditions were reached after removal of deoxycholate with 27 mg Triton X-100 per gram of moist Amberlite XAD-2 beads and 7 micrograms protein/mg of phospholipid. Uptake of pyruvate into proteoliposomes and sensitivity ...

journal_title：Acta biochimica Polonica

authors： Nałecz KA,Zambrowicz BE

更新日期：1990-01-01 00:00:00

abstract：:Analysis of 664 known structures of protein kinase complexes with halogenated ligands revealed 424 short contacts between a halogen atom and a potential protein X-bond acceptor, the topology and geometry of which were analyzed according to the type of a halogen atom (X = Cl, Br, I) and a putative protein X-bond accept...

journal_title：Acta biochimica Polonica

authors： Poznański J,Winiewska M,Czapinska H,Poznańska A,Shugar D

更新日期：2016-01-01 00:00:00

abstract：:A set of metabolite carriers operates the traffic of numerous molecules consumed or produced in mitochondrial matrix and/or cytosolic compartments. As their existence has been predicted by the chemiosmotic theory, the first challenge, in the late sixties, was to prove their presence in the inner mitochondrial membrane...

journal_title：Acta biochimica Polonica

authors： Sluse FE

更新日期：1996-01-01 00:00:00

abstract：:Calretinin (CR) is a neuronal EF-hand protein previously characterized as a calcium (micromolar affinity) binding protein. CR-containing neurons are spared in some neurodegenerative diseases, although it is as yet unconfirmed how CR plays an active role in this protection. Higher levels of some metal cations (e.g. cop...

journal_title：Acta biochimica Polonica

authors： Groves P,Palczewska M

更新日期：2001-01-01 00:00:00

abstract：:The present study was undertaken to evaluate the protective effects of Linum usitatissimum oil (LuO) against sub-chronic Roundup (RDP)-induced toxicity and oxidative stress in rats. Rats were divided into four groups: control group (no treatment), RDP group (Roundup at 269.9 mg/kg b.w.), LuO group (0.5 g/kg b.w. of Lu...

journal_title：Acta biochimica Polonica

authors： Djaber N,Ounaceur LS,Moubine BN,Khaldi T,Rouag M,Berrouague S,Amara H,Taibi F,Boumendjel M,Boumendjel A,Messarah M

更新日期：2020-03-18 00:00:00

abstract：:Matrix metalloproteinase-2 (MMP-2) is an enzyme with proteolytic activity against matrix proteins, particularly basement membrane constituents. A single nucleotide polymorphism (SNP) at -1306, which disrupts a Sp1-type promoter site (CCACC box), displayed a strikingly lower promoter activity with the T allele. In the ...

journal_title：Acta biochimica Polonica

authors： Saeed HM,Alanazi MS,Alshahrani O,Parine NR,Alabdulkarim HA,Shalaby MA

更新日期：2013-01-01 00:00:00

abstract：:1. The activity of trypsin inhibitors in lung and pancreas increased with age of the animals. 2. In foetal lung the activity of the basic Kunitz-type inhibitor was 1% that, and in calf lung 5-30% that, found in adult animals. 3. In foetal pancreas the basic Kunitz-type inhibitor was not detected, and in calf pancreas ...

journal_title：Acta biochimica Polonica

authors： Wilusz T,Wilimowska-Pelc A,Mejbaum-Katzenellenbogen W

更新日期：1976-01-01 00:00:00

abstract：:This study examined the antiproliferative effects of β-escin (E) in cancer cells. The study showed that E inhibited cancer cells growth in a dose-dependent manner. The flow cytometric analysis revealed an escin-induced increase in the sub-G1 DNA content, which is considered to be a marker of apoptosis. Apoptosis was a...

journal_title：Acta biochimica Polonica

authors： Mojžišová G,Kello M,Pilátová M,Tomečková V,Vašková J,Vaško L,Bernátová S,Mirossay L,Mojžiš J

更新日期：2016-01-01 00:00:00

abstract：:Human mitochondrial polynucleotide phosphorylase (hPNPase) is an exoribonuclease localized in mitochondria. The exact physiological function of this enzyme is unknown. Recent studies have revealed the existence of a relationship between induction of hPNPase mRNA and both cellular senescence and growth arrest of melano...

journal_title：Acta biochimica Polonica

authors： Gewartowski K,Tomecki R,Muchowski L,Dmochow Ska A,Dzwonek A,Malecki M,Skurzak H,Ostrowski J,Stepien PP

更新日期：2006-01-01 00:00:00

abstract：:Bovine vitreous humour contains 0.6 +/- 0.04 mg of proteins per cm3. Three main protein fractions were obtained by CM-cellulose chromatography and their homogeneity was confirmed by isoelectric focusing and SDS-gel electrophoresis. The Mr and pl values of the separated fractions were: fraction I, 67,000 and 4.02; frac...

journal_title：Acta biochimica Polonica

authors： Wolańska M,Bańkowski E

更新日期：1989-01-01 00:00:00

abstract：:Lanthanides, also called rare-earth elements, are an interesting group of 15 chemically active, mainly trivalent, f-electronic, silvery-white metals. In fact, lanthanides are not as rare as the name implies, except for promethium, a radioactive artificial element not found in nature. The mean concentrations of lanthan...

journal_title：Acta biochimica Polonica

authors： Pałasz A,Czekaj P

更新日期：2000-01-01 00:00:00

abstract：:The rate of elimination from rat and goat circulation of 125I-labelled goat haemoglobin and its complexes with human and goat haptoglobin in goat circulation, was studied. The half-life time t1/2 of haemoglobin in rat circulation was 1.5h, whereas in goat circulation -- 4 h, and was 10 times shorter than t1/2 for its ...

journal_title：Acta biochimica Polonica

authors： Osada J,Nowacki W

更新日期：1989-01-01 00:00:00

abstract：:DNA methylation and histone modifications are major components of cellular epigenetic pattern determining gene expression. Cancer cells have their own epigenetic array, which can be different in cells of primary and metastatic tumors. In the present work we investigated effects of 1 mM valproic acid (VPA), a histone d...

journal_title：Acta biochimica Polonica

authors： Ghecham A,Senator A,Pawlowska E,Bouafia W,Błasiak J

更新日期：2019-07-09 00:00:00

abstract：:The fucosyltransferase NodZ is involved in the biosynthesis of the nodulation factor in nitrogen-fixing symbiotic bacteria. It catalyzes alpha1,6 transfer of l-fucose from GDP-fucose to the reducing residue of the synthesized Nod oligosaccharide. We present the structure of the NodZ protein from Bradyrhizobium express...

journal_title：Acta biochimica Polonica

authors： Brzezinski K,Stepkowski T,Panjikar S,Bujacz G,Jaskolski M

更新日期：2007-01-01 00:00:00

abstract：:Trans-diamminedichloroplatinum(II) (trans-DDP) forms with DNA at 37 degrees C, more numerous interstrand cross-links than cis-DDP in the isolated DNA and DNA in the chromatin complex. An increase in the temperature to 42.5 degrees C had no effect on the interstrand cross-links of DND-Pt-DNA formed by the two isomers, ...

journal_title：Acta biochimica Polonica

authors： Kulamowicz I,Walter Z,Krupa R

更新日期：1990-01-01 00:00:00

abstract：:Recently, embryo muscle development, which is crucial for postnatal skeletal muscle growth, has been investigated widely. Nutrients in ovo were suggested to be critical in embryo muscle development since the chick growth mostly relies on nutrients in eggs at the early developmental stage. Phytosterol esters (PE), whic...

journal_title：Acta biochimica Polonica

authors： Wang L,Zuo X,Zhao W,Zhou G,Luo L,Yang K,Shu G,Wang S,Gao P,Zhu X,Jiang Q,Wang L

更新日期：2020-03-19 00:00:00

abstract：:Chromatin of lower eukaryote Physarum polycephalum, while showing typical nucleosomal organization, reveals upon digestion with micrococcal nuclease certain features not found in chromatins of higher eukaryotes, the most pronounced of which is the unusual pattern of degradation of core-size DNA, without accumulation o...

journal_title：Acta biochimica Polonica

authors： Staroń K,Jerzmanowski A,Fronk J,Toczko K

更新日期：1980-01-01 00:00:00

abstract：:Description of the recognition specificity between proteins and nucleic acids at the level of molecular interactions is one of the most challenging tasks in biophysics. It is key to understanding the course and control of gene expression and to the application of the thus acquired knowledge in chemotherapy. This revie...

journal_title：Acta biochimica Polonica

authors： Stolarski R

更新日期：2003-01-01 00:00:00

abstract：:The pools of Arg, Gly, His, Ile, Ser, Glu, Leu, Val and Asp were lower during photosynthesis at 1% O2 concentration. At the same time specific radioactivity of a number of amino acids--following 14CO2 incorporation--was different than that at atmospheric O2 concentration. This is probably due to the inhibition of the ...

journal_title：Acta biochimica Polonica

authors： Niziołek S,Bielawski W,Nalborczyk E

更新日期：1982-01-01 00:00:00

abstract：:Cytosine nucleoside deaminase (EC 3.5.4.5) from Salmonella typhimurium LT2 catalyses the deamination of ribo-, deoxyribo- and arabinosyl nucleosides of cytosine alkylated at the C-5, but not at the N3 or exocyclic N4, of the pyrimidine ring. The enzyme was inert towards analogues etherified at the 3'-OH and 5'-OH of t...

journal_title：Acta biochimica Polonica

authors： Krajewska E,Shugar D

更新日期：1975-01-01 00:00:00

abstract：INTRODUCTION:Hepatitis C virus (HCV) infection is a global health problem which can lead to liver cirrhosis or hepatocellular carcinoma in one-fifth of chronically infected patients. MATERIALS AND METHODS:The study group consisted of 123 patients: 90 with HCV mono- and 33 with HIV/HCV co-infection, who were treated wi...

journal_title：Acta biochimica Polonica

authors： Jabłonowska E,Piekarska A,Koślińska-Berkan E,Omulecka A,Szymańska B,Wójcik K

更新日期：2012-01-01 00:00:00

abstract：:1. In frog liver, tyrosine aminotransferase is located mainly in cytoplasm. The enzyme is an anionic protein of mol. wt. 115 000 daltons, specific toward 2-oxoglutarate. The enzyme separates on ion-exchange chromatography into two active forms. 2. Administration of triiodotyronine in vivo induces the activity of the e...

journal_title：Acta biochimica Polonica

authors： Laskowska-Klita T

更新日期：1975-01-01 00:00:00

abstract：:We recently reported that kinobeon A, produced from safflower cells, suppressed the free radical-induced damage of cell and microsomal membranes. In the present study, we investigated whether kinobeon A quenches singlet oxygen, another important active oxygen species. Kinobeon A inhibited the singlet oxygen-induced ox...

journal_title：Acta biochimica Polonica

authors： Kambayashi Y,Takekoshi S,Nakano M,Shibamori M,Hitomi Y,Ogino K

更新日期：2005-01-01 00:00:00

abstract：:Aspergillus fumigatus is one of the most prevalent airborne fungal pathogens causing infections worldwide. Most A. fumigatus strains are susceptible to azoles, which are administered as the first line therapeutics. However, during last decade the acquired resistance to triazoles by these species has been described. Th...

journal_title：Acta biochimica Polonica

authors： Brillowska-Dąbrowska A,Mroczyńska M,Nawrot U,Włodarczyk K,Kurzyk E

更新日期：2015-01-01 00:00:00

abstract：:Chemical instability of some of the phosphodiester bonds, often observed in large RNAs, visualizes the autocatalytic properties of this class of nucleic acids. Unexpectedly, selective hydrolysis occurs also in short oligoribonucleotides (as short as a tetramer or hexamer). Herein, we describe additional experiments wh...

journal_title：Acta biochimica Polonica

authors： Bibiłło A,Ziomek K,Figlerowicz M,Kierzek R

更新日期：1999-01-01 00:00:00

abstract：:Human STAU1 is one member of the family of double-stranded RNA (dsRNA)-binding proteins. It is thought to function in transporting mRNA, controlling translation and eliciting mRNA decay in neurons, and to function in infection of influenza virus and human immunodeficiency virus type 1 (HIV-1). Four transcripts coding ...

journal_title：Acta biochimica Polonica

authors： Fa-Hui N,Hai-Feng Y,Rui-Feng Q,Xin L,Cai-Bin W

更新日期：2008-01-01 00:00:00

abstract：:Mitochondria were prepared from rat liver, solubilized with Triton X-100 and submitted to chromatography on dry hydroxylapatite. The pass-through from the column, containing a mixture of mitochondrial carriers, was processed further by triazine dye affinity chromatography and optimal conditions for binding and elution...

journal_title：Acta biochimica Polonica

authors： Szewczyk A,Poddana H,Nałecz MJ

更新日期：1990-01-01 00:00:00

abstract：:Clofarabine (2-chloro-2'-fluoro-2'-deoxyarabinosyladenine, ClF), a second-generation 2'-deoxyadenosine analog, possesses manifold anti-cancer activities. Our previous reports and some of others demonstrate the potential capacity of ClF to regulate the epigenetic machinery. The study presented here is the first to inve...

journal_title：Acta biochimica Polonica

authors： Kaufman-Szymczyk A,Lubecka K

更新日期：2020-01-30 00:00:00

abstract：:Kainate is a glutamate analog that produces neuronal excitation resulting in seizures within hours following its intraperitoneal injection into adult rats. Then, at 2-3 days after the treatment, neurodegeneration of apoptotic character can be observed in limbic system. As a consequence, plastic reorganization and glia...

journal_title：Acta biochimica Polonica

authors： Kaminska B,Filipkowski RK,Biedermann IW,Konopka D,Nowicka D,Hetman M,Dabrowski M,Gorecki DC,Lukasiuk K,Szklarczyk AW,Kaczmarek L

更新日期：1997-01-01 00:00:00

abstract：:1. Gluconeogenesis from glutamine, fumarate, pyruvate, glutamine plus fumarate, and glutamine plus pyruvate, was generally higher at pH 7.1 than at pH 7.4 and 7.7, whereas ammoniagenesis did not depend on the pH of the medium. 2. The intermediates of the Krebs cycle decreased ammonia formation from glutamine, raising ...

journal_title：Acta biochimica Polonica

authors： Strzelecki T,Rogulski J

更新日期：1977-01-01 00:00:00