Abstract:
PURPOSE:To review the mammographic features of screening interval breast cancers and to compare the tumor size, histologic grade, and lymph node involvement with those in screening-detected and unscreened symptomatic cancers. MATERIALS AND METHODS:Screening mammography was performed in 72,773 women aged 50-64 years. Ninety interval cancers were identified in 89 women. The mammographic and histopathologic features of these cancers were analyzed. RESULTS:At review of the screening mammograms, interval cancers were classified into four groups: 51 true-positive, 20 false-negative, seven mammographically occult, and 12 unclassified. The most common missed abnormality in the false-negative cases was architectural distortion. Interval cancers were larger, of higher grade, and more likely to have lymph node involvement than screening-detected tumors and were of similar size, histologic grade, and stage of lymph node involvement as symptomatic tumors. CONCLUSION:Prognosis in interval cancers is similar to that in symptomatic, unscreened tumors and statistically significantly worse than that in screening-detected cancers.
journal_name
Radiologyjournal_title
Radiologyauthors
Burrell HC,Sibbering DM,Wilson AR,Pinder SE,Evans AJ,Yeoman LJ,Elston CW,Ellis IO,Blamey RW,Robertson JFdoi
10.1148/radiology.199.3.8638010subject
Has Abstractpub_date
1996-06-01 00:00:00pages
811-7issue
3eissn
0033-8419issn
1527-1315journal_volume
199pub_type
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