[Autoimmune diseases of the peripheral cornea. Immunopathology, clinical aspects and therapy].

Abstract:

:Noninfectious ulceration of the peripheral cornea remains a major diagnostic and therapeutic challenge. The pathogenesis in most of these disorders is unclear, however, on the basis of systemic connective tissue diseases, autoimmune mechanisms are most likely involved. The peripheral cornea has distinct morphological and immunological characteristics that predispose for inflammatory reactions. Major differences exist regarding humoral and cellular components of the immune system. In the peripheral cornea there is more high-molecular IgM and initial complement component C1 than in the central cornea and may predispose for immune complex formation. The close contact to the conjunctival vasculature provides the basis necessary to generate an immune response. Langerhans cells and macrophages as important antigen presenting and processing cells are present in higher number in the peripheral cornea. Autoimmune diseases that affect the peripheral cornea include collagen vascular diseases and Mooren's ulcer. Although this association is obvious in advanced rheumatoid arthritis more subtle forms of polyarteritis nodosa or systemic lupus erythematosus require careful medical evaluation and workup. Ocular manifestations may present as the initial clinical signs and require careful workup in these potentially lethal disorders.

journal_name

Klin Monbl Augenheilkd

authors

Pleyer U,Bergmann L,Krause A,Hartmann C

doi

10.1055/s-2008-1035173

subject

Has Abstract

pub_date

1996-02-01 00:00:00

pages

73-81

issue

2

eissn

0023-2165

issn

1439-3999

journal_volume

208

pub_type

杂志文章,评审
  • [Better prognosis for amblyopics by means of full prismatic correction after monocular treatment (author's transl)].

    abstract::Binocular training with full prismatic correction after the monocular therapy by occlusion brings a further improvement of the visual acuity as well as shown in a study of 29% (138 cases) of 469 selected cases with binocular problems and 43% (260 cases) of about 600 unselected cases of squint actually in treatment in ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Pestalozzi D,Schwarzenbach A

    更新日期:1979-09-01 00:00:00

  • [Topography of the posterior chamber lens (author's transl)].

    abstract::The position of the implanted posterior chamber lens (Shearing type) in human cadaver eyes was photographed from the rear. We were especially interested in the position of the loops. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057359

    authors: Schnaudigel OE

    更新日期:1981-12-01 00:00:00

  • [The frequency of various forms of senile cataract (author's transl)].

    abstract::On classifying 1000 senile cataracts it was found that in pure cataract forms - starting from the cortex - the typical grey senile cataract (cataracta supranuclearis) mostly occurs with a clear nucleus. The dense permeability cataract (cataracta subcapsularis) most frequently shows a dense grey clouding of the nucleus...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Pau H

    更新日期:1976-08-01 00:00:00

  • [Autoregulation in ischemia of the optic nerve in the human].

    abstract:BACKGROUND:Autoregulation is defined as the maintenance of constant blood flow in a vascular system in spite of changes in perfusion pressure (PPm). MATERIALS AND METHODS:PPm was decreased by increasing the intraocular pressure (IOP) with a suction cup and optic nerve blood flow was measured with the laser Doppler flo...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Titzé P,Hero M,Petrig BL,Cranstoun SD,Riva CE

    更新日期:1997-05-01 00:00:00

  • [Impact of cataract surgery on intraocular pressure after filtering operation due to primary open angle glaucoma and secondary glaucoma in pseudoexfoliation syndrome].

    abstract:PURPOSE:To analyse the impact of cataract surgery after filtering operation on the intraocular pressure (IOP) due to primary open angle glaucoma (pOAG) versus secondary open angle glaucoma in pseudoexfoliation syndrome (PEX). The regulation of IOP was evaluated on the basis of criteria of advanced glaucoma intervention...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2002-26725

    authors: Wakili N,Seitz B,Hayler J,Händel A,Jünemann A

    更新日期:2002-03-01 00:00:00

  • [Intravitreal Ranibizumab Injection for the Treatment of Occult and Classic CNV in Exsudative AMD].

    abstract:BACKGROUND:Double-blind, randomised, placebo-controlled and multicentre studies have proven an increase in visual acuity in one-third of the patients receiving Ranibizumab (0.5 mg) injections, who suffer from exsudative AMD. The purpose of this study was to evaluate the early effects of intravitreal Ranibizumab therapy...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0029-1245131

    authors: Maier MM,Feucht N,Fegert C,Fiore B,Winkler von Mohrenfels C,Lohmann C

    更新日期:2011-02-01 00:00:00

  • [Notes on a modification of Cüpper's Faden operation (the "false faden") (author's transl)].

    abstract::A "false faden operation was performed in 13 cases. In contrast to Cüpper's faden operation it had no lasting effect. The results of other authors were not confirmed. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Kaufmann H

    更新日期:1981-03-01 00:00:00

  • [Spontaneous healing of a cataract with secondary glaucoma (author's transl)].

    abstract::A 55-year-old man was referred to our clinic with a mature, swollen cataractous lens and a secondary phakolytic glaucoma. However, the patient refused to undergo surgery. Twelve years later he returned. Meanwhile the lens had been almost completely absorbed; visual acuity was 20/32 and there had been no severe damage...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1055071

    authors: Röver J,Witschel H

    更新日期:1982-04-01 00:00:00

  • [Changes of the anterior eye segment after eye muscle surgery--evaluation by optical coherence tomography in adults].

    abstract:BACKGROUND:In the light of studies in children which showed no significant changes concerning anterior chamber depth, central corneal thickness and chamber angle width after eye muscle surgery, the aim of this study was to evaluate such changes in adults by means of optical coherence tomography. PATIENTS AND METHODS:U...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0029-1245748

    authors: Lüchtenberg M,Haeussler-Sinangin Y,Kohnen T,Kuhli-Hattenbach C,Koss MJ,Schalnus R

    更新日期:2010-10-01 00:00:00

  • [Treatment of a case of coloboma-like papillar excavation and maculopathy with photo-coagulation (author's transl)].

    abstract::A study is presented of a case of serous detachment of the mucula secondary to congenital pit of the optic disc. We observed during fluorescein angiography a late leakage of dye at the temporal margin of the disc. A lasercoagulation of this lesion gave a favourable result. All these findings support Gass' explanation ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Saraux H,Lefrançois A

    更新日期:1977-12-01 00:00:00

  • [Endonasal dacryocystorhinostomy with transillumination of the lacrimal sac: implementation and results].

    abstract:PATIENTS:Since Mai 1991 we performed a total of 17 endonasal dacryocystorhinostomies under transillumination of the lacrimal sac on 15 patients with lacrimal obstruction aged 11 to 88 years. 11 patients with 12 operations were followed up between 40 and 393 days (mean of 5.6 months). RESULTS:In all cases the connectio...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: von Büren M,Forrer A,Fiebach A

    更新日期:1994-05-01 00:00:00

  • [Change of retinal oxygen saturation in healthy subjects and in early stages of diabetic retinopathy during breathing of 100% oxygen].

    abstract:BACKGROUND:Disturbances in the microcirculation are a source of retinal diabetic alterations. Comprehensive studies of blood flow parameters have been performed, but it is not known how ageing, duration of diabetes, blood sugar, glycolysed haemoglobin and elevated systemic blood pressure act in the early stages of diab...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2007-963156

    authors: Schweitzer D,Lasch A,van der Vorst S,Wildner K,Hammer M,Voigt U,Jütte M,Müller UA

    更新日期:2007-05-01 00:00:00

  • [The American Optical non-contact tonometer and its results compared with the Goldmann applanation tonometer (author's transl)].

    abstract::Intraocular pressure (IOP) of 617 eyes was measured with both an AO non-contact tonometer (NCT) and a Goldmann applanation tonometer (GAT). - Statistical evaluation and the scattergram gave the following results: Correlation coefficient r = 0.74. Regression line y = 3.01 + 0.8x. Close agreement between mean GAT (17.8 ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057700

    authors: Derka H

    更新日期:1980-11-01 00:00:00

  • [Closure of the central artery of the retina in progressive scleroderma (author's transl)].

    abstract::In the present paper a case of generalized scleroderma with concomitant central arterial occlusion is reported. To our knowledge this coincidence of generalized scleroderma and central arterial occlusion has not been described so far. As fibrinoid necrosis and proliferative changes of the choroidal vessels occur with ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Berndt K,Hoffmann A

    更新日期:1977-10-01 00:00:00

  • Strabismus Surgery of Consecutive Exotropia.

    abstract:PURPOSE:The purpose of this study was to determine the surgical outcome, dose-effect (DE), and degree of binocularity in patients undergoing surgery for consecutive exotropia following initial surgery of esotropia. PATIENTS/METHODS:Twenty-one patients were identified. We analyzed the mean angle of deviation pre- and p...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/a-1097-5653

    authors: Janeschitz-Kriegl L,Roulez F,Wipf MM,Palmowski-Wolfe A

    更新日期:2020-04-01 00:00:00

  • [Experimental studies of the significance of the renin-angiotensin system in the retina. A review].

    abstract::BACKGROUND Many peptides now identified in the brain were previously thought of as exclusively peripheral hormones. Among those, the renin-angiotensin system (RAS) is not only found to be of great importance in peripheral vasomotor and electrolyte homeostasis but also acts as neurotransmitter or modulator in the centr...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1045478

    authors: Jacobi PC,Jurklies B,Kohler K,Zrenner E

    更新日期:1994-06-01 00:00:00

  • The Australian Corneal Graft Registry (ACGR).

    abstract::The value of a register of corneal grafts is that it can provide new data about the long-term outcome of corneal transplantation and may allow a more reasoned distribution of scarce donor corneas. The large numbers of cases and events can accommodate wide variations in practice patterns without losing statistical powe...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1045527

    authors: Coster DJ,Williams KA

    更新日期:1994-11-01 00:00:00

  • [Possibilities of microsurgery on ophthalmic vessels (author's transl)].

    abstract::Ciliary arteries, isolated from the eyes of human cadavers, were incised or severed under the microscope in order to test the technical possibilities of placing sutures or creating leak-proof anastomoses in ophthalmic vessels. Commercially available, minute atraumatic needles and 10-0 "Ethilon" or 15-0 Supramid suture...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057589

    authors: Gundorowa RA,Galtschin AS

    更新日期:1980-06-01 00:00:00

  • [The indications for the preventive treatment of retinal detachment (author's transl)].

    abstract::The author describes the genuine indications for the preventive treatment of retinal detachment. He was above all guided by the minute observations of the eye fundus of two eyes with the Goldmann-glass. The author's long experience and his auto-observation of the retinal detachment operation and of preventive treatmen...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Paufique L

    更新日期:1977-06-01 00:00:00

  • [Ocular blood flow of cats after local administration of pilocarpine, phenylephrine, and of a mixture of both drugs (author's transl)].

    abstract::Radioactively labelled microspheres (size 15 micron) were used to determine the regional blood flow in cats before and 15, 30 and 45 minutes after unilateral drug administration. In four experimental groups, each consisting of five animals, two drops of the drug were administered into the conjunctival sac. The blood f...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Kaskel D,Spangenberg U,Rudolf H,Hübel H,Witt N,Baumgart W

    更新日期:1978-03-01 00:00:00

  • [In memory of Albrecht von Graefe's 150th birthday (author's transl)].

    abstract::On the occasion of the 150th aniversary of Albrecht von Graefe's birthday his short but successful activity for ophthalmology is brought back to mind. Within the scape of his life-history the attempt is made to portray a man in his time and to waken his importance as ophthalmologist a significant still in our days. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Hoffmann-Axthelm W,Wollensak J

    更新日期:1978-05-01 00:00:00

  • [Comparative investigation of the etiology of visual field defects after epimacular surgery].

    abstract:BACKGROUND:Sectorial visual field defects after macular hole surgery were described by several authors. The intraocular gas tamponade is discussed to be a possible causative factor for this complication. PATIENTS AND METHODS:Goldmann perimetry and threshold perimetry were performed preoperatively and 6 weeks postopera...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2002-32887

    authors: Dillinger P,Lägel H,Mester U

    更新日期:2002-06-01 00:00:00

  • [Alternate day squint (author's transl)].

    abstract::3 cases of cyclical convergent strabismus (48 hour rhythm) were investigated. In contrast to intermittant strabismus, cyclical strabismus is not fatigue dependant. An alteration in the rhythm of the cyclical esotropia was produced by wearing prisms, red glasses or occlusion for several days. This observation indicates...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Schmidt D,Mattheus S

    更新日期:1975-12-01 00:00:00

  • [Ocular changes in MELAS syndrome].

    abstract::The present paper reports on the clinical findings of a 34-year-old male patient with MELAS syndrome. MELAS syndrome (mitochondrial encephalomyopathy, lactic acidosis and strokelike episodes) belongs to a group of syndromes called mitochondrial encephalomyopathies that are characterized by changes of the mitochondrial...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046280

    authors: Küchle M,Brenner PM,Engelhardt A,Naumann GO

    更新日期:1990-09-01 00:00:00

  • [Measurement of the diameter of segments of retinal branch vessels in digital fundus images - An experimental study of the method and reproducibility].

    abstract:PURPOSE:The aim of this study was the evaluation of new algorithms to measure diameter of segments of retinal branch vessels offline in local dependence and independent by observer. Methods 360 flashed fundus images (camera FF 450 ZEISS Germany, Visualis IMEDOS GmbH Weimar/Germany) of 12 eyes of healthy volunteers (10 ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2001-17640

    authors: Nagel E,Münch K,Vilser W

    更新日期:2001-09-01 00:00:00

  • [The best spectacles for vehicle drivers (author's transl)].

    abstract::Spectacles worn by vehicle drivers should fulfil the demands set down by DIN 58 216 standards and should furthermore be constructed in such a manner that the binocular field of vision is impaired as little as possible. In this connection, the nasal parts of the frame are particularly important. The external and intern...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Reiner J,Grewe R

    更新日期:1978-07-01 00:00:00

  • [Comparing specific disc findings of a European and a Bantu population].

    abstract:BACKGROUND:Glaucoma is the main cause of irreversible blindness in the world. Because of the increasing mean age, glaucoma is expected to become more common in the developing countries. Besides tonometry and perimetry the appearance of the optic nerve head is a main part of glaucoma diagnosis. Ethnic differences have t...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0028-1109644

    authors: Krueger H,Schittkowski MP,Kilangalanga N,Hopkins A,Guthoff R

    更新日期:2009-10-01 00:00:00

  • [Ocular involvement in MuSK antibody-positive myasthenia gravis].

    abstract:BACKGROUND:Antibodies (Ab) against the acetylcholine receptor (AChR) are found in 80 - 90 % of generalized myasthenia gravis (MG), but only in 50 % of pure ocular MG. Furthermore, Ab against the muscle-specific receptor tyrosine kinase (MuSK) were detected in 38 - 54 % of patients with AChR-Ab-negative ("seronegative")...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2005-858629

    authors: Bau V,Hanisch F,Hain B,Zierz S

    更新日期:2006-01-01 00:00:00

  • [Chronic eyelid oedema and rosacea (Morbus Morbihan): diagnostic and therapeutic challenges].

    abstract:BACKGROUND:Morbus Morbihan is a rare complication of rosacea, consisting of a persistent lymphoedema of the upper part of the face. It has typically a chronic course, unspecific histopathological findings and an extreme refractoriness to therapy. PATIENTS AND METHODS:Between February 2008 and January 2010, 5 patients ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0029-1245960

    authors: Renieri G,Brochhausen C,Pfeiffer N,Pitz S

    更新日期:2011-01-01 00:00:00

  • [Laser treatment for tightening the trabecular meshwork in open-angle glaucoma (trabeculoplasty)].

    abstract::Forty eyes with medically uncontrolled open-angle glaucoma underwent argon laser therapy through 360 degrees of the trabecular meshwork. The mean pressure change in the treated eyes after two weeks showed a decrease of 9.95 mmHg. Thirty-five eyes (87.5%) were clinically controlled (tension less than or equal to 20 mmH...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1055262

    authors: Strasser G,Witzmann K

    更新日期:1982-11-01 00:00:00