Abstract:
:The nature of the water-soluble products formed by incubating labelled estradiol with uterine peroxidase in the presence of H2O2 and tyrosine was examined by two-dimensional thin-layer chromatography and high voltage electrophoresis. It was shown that the steroid and amino acid were associated in a 1:2 or 1:3 ratio and evidence was provided by 3H-exchange for the interaction of tyrosine with ring A of estradiol at C-2 and C-4. The possible role of estrogen-induced peroxidase in the uterus in vivo is discussed.
journal_name
Steroidsjournal_title
Steroidsauthors
Jellinck PH,McNabb Tdoi
10.1016/0039-128x(77)90072-1subject
Has Abstractpub_date
1977-04-01 00:00:00pages
525-37issue
4eissn
0039-128Xissn
1878-5867pii
0039-128X(77)90072-1journal_volume
29pub_type
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