Abstract：
:A class of models is considered in which the number of unknown parameters exceeds the number of independent equations that are derived from the input/observation configuration. It is shown that, under certain circumstances, if the number of unknown parameters is sufficiently decreased by setting some of the exit parameters to zero, then the fallaciously derived model has the following interesting properties. The functions of time that give the amounts in the compartments are constant multiples of their counterparts in the fallacious model. A subset of the fallacious fractional transfer coefficients have the same values as their counterparts in the true model whereas others yield interval bounds. These and related results are obtained from a method based on positive linear Lyapunov functions.
journal_name
Math Bioscijournal_title
Mathematical biosciencesauthors
Eisenfeld Jdoi
10.1016/0025-5564(95)00049-6subject
Has Abstractpub_date
1996-03-01 00:00:00pages
111-40issue
2eissn
0025-5564issn
1879-3134pii
0025556495000496journal_volume
132pub_type
杂志文章abstract：:The acetone-butanol (AB) fermentation process in the anaerobic endospore-forming Gram-positive bacterium Clostridium acetobutylicum is useful as a producer of biofuels, particularly butanol. Recent work has concentrated on trying to improve the efficiency of the fermentation method, either through changes in the envir...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2012.11.004
更新日期：2013-02-01 00:00:00
abstract：:A simple model of Freeman and Johnson on cutaneous mechanoreceptors is modified by introducing mechanisms for hyperexcitation and refractoriness. These lead to significant improvements in the match between the neural and model data. ...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/0025-5564(94)00083-c
更新日期：1995-11-01 00:00:00
abstract：:Modeling a cell's response to encroaching ice has informed the development of cryopreservation protocols for four decades. It has been well documented that knowledge of the cellular state as a function of media and cooling rate faciliate informed cryopreservation protocol design and explain mechanisms of damage. Howev...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2019.108240
更新日期：2019-10-01 00:00:00
abstract：:A novel multi-input single output (MISO) black-box sigmoid model is developed to simulate the biosorption of heavy metal cations by the fission yeast from aqueous medium. Validation and verification of the model is done through statistical chi-squared hypothesis tests and the model is evaluated by uncertainty and sens...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2015.04.007
更新日期：2015-07-01 00:00:00
abstract：:Based on previously published experimental observations and mathematical models for Hes1, p53 and NF-kappaB gene expression, we improve these models through a distributed delay formulation of the time lag between transcription factor binding and mRNA production. This description of natural variability for delays intro...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2006.08.010
更新日期：2007-02-01 00:00:00
abstract：:A non-traditional approach of fitting dynamic resource biomass models to data is developed in this paper. A variational adjoint technique is used for dynamic parameter estimation. In the variational formulation, a cost function measuring the distance between the model solution and the observations is minimized. The da...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(02)00178-5
更新日期：2003-03-01 00:00:00
abstract：:Three-species food-chain models, in which the prey population exhibits group defense, are considered. Using the carrying capacity of the environment as the bifurcation parameter, it is shown that the model without delay undergoes a sequence of Hopf bifurcations. In the model with delay it is shown that using a delay a...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/0025-5564(92)90079-c
更新日期：1992-09-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2008.05.006
更新日期：2008-07-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2019.108218
更新日期：2019-09-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(01)00081-5
更新日期：2001-12-01 00:00:00
abstract：:Inflammation plays a critical role in the development and progression of cancer, evident in multiple patient populations manifesting increased, non-resolving inflammation, such as inflammatory bowel disease, viral hepatitis and obesity. Given the complexity of both the inflammatory response and the process of oncogene...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2014.07.009
更新日期：2015-02-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(01)00101-8
更新日期：2002-03-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(98)00008-x
更新日期：1998-06-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/0025-5564(89)90054-0
更新日期：1989-07-01 00:00:00
abstract：:The problem of moment closure is central to the study of multitype stochastic population dynamics since equations for moments up to a given order will generally involve higher-order moments. To obtain a Normal approximation, the standard approach is to replace third- and higher-order moments by zero, which may be seve...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(00)00037-7
更新日期：2000-11-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2004.03.001
更新日期：2004-07-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(01)00071-2
更新日期：2001-09-01 00:00:00
abstract：:In this paper, a mathematical modeling framework is presented which describes the growth, encapsulation, and transcapsular spread of solid tumors. The model is based on the physical forces and cellular interactions involved in tumorigenesis and is used to test and compare the active (foreign body hypothesis) and passi...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(02)00118-9
更新日期：2002-11-01 00:00:00
abstract：:A beam balance is analyzed as a model that describes Weber's law. The mathematical derivations of the torques on a beam balance produce a description that is strictly compatible with that law. The natural relationship of the beam balance model to Weber's law provides for an intuitive understanding of the relationship ...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/0025-5564(94)90083-3
更新日期：1994-07-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章,评审
doi：10.1016/0025-5564(95)00047-x
更新日期：1996-02-01 00:00:00
abstract：:This paper investigates the effects of vaccination on the dynamics of infectious disease, which is spreading in a population concurrently with awareness. The model considers contributions to the overall awareness from a global information campaign, direct contacts between unaware and aware individuals, and reported ca...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2017.09.007
更新日期：2017-12-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(98)10083-4
更新日期：1999-03-15 00:00:00
abstract：:A significant consideration in modeling systems with stages is to obtain models for the individual stages that have probability density functions (pdfs) of residence times that are close to those of the real system. Consequently, the theory of residence time distributions is important for modeling. Here I show first t...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(02)00110-4
更新日期：2002-11-01 00:00:00
abstract：:An epidemic model with multiple stages of infection is studied. The model allows for infected individuals to move from advanced stages of infection back to less advanced stages of infection. A threshold parameter which determines the local stability of the disease free equilibrium is found and interpreted. Under condi...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(02)00149-9
更新日期：2003-01-01 00:00:00
abstract：:We investigate an SIR epidemic model with discrete age groups to understand the transmission dynamics of an infectious disease in a host population with an age structure. We derive the basic reproduction number R0 and show that it is a sharp threshold parameter. If R0≤1, the disease-free equilibrium E0 is globally sta...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2018.12.003
更新日期：2019-02-01 00:00:00
abstract：:A stochastic epidemic model is formulated for the study of the protective effects of vaccination in a population that is stratified by vaccine-related factors. The epidemic model is transformed into a counting process, and then martingale-based methods are used to provide estimators of vaccine efficacy and their varia...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/0025-5564(93)90028-9
更新日期：1993-09-01 00:00:00
abstract：:The existence of cooperation in this world is a mysterious phenomenon. One of the mechanisms that explain the evolution of cooperation is repeated interaction. If interactions between the same individuals repeat and individuals cooperate conditionally, cooperation can evolve. A previous study pointed out that if indiv...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2017.04.002
更新日期：2017-07-01 00:00:00
abstract：:In this paper, we consider a deterministic malaria transmission model with standard incidence rate and treatment. Human population is divided into susceptible, infectious and recovered subclasses, and mosquito population is split into susceptible and infectious classes. It is assumed that, among individuals with malar...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2015.05.005
更新日期：2015-08-01 00:00:00
abstract：:Frailty models are becoming increasingly popular in multivariate survival analysis. Shared frailty models in particular are often used despite their limitations. To overcome their disadvantages numerous correlated frailty models were established during the last decade. In the present study, we examine bivariate correl...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2004.11.010
更新日期：2005-11-01 00:00:00
abstract：:In the Western world approximately 10% of the population experience severe depression at least once in their lifetime and many more experience a mild form of depression. Depression has been associated with malfunctions in the hypothalamus-pituitary-adrenal (HPA) axis. We suggest a novel mechanistic non-linear model ca...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2014.07.013
更新日期：2014-11-01 00:00:00
