Abstract：
:The problem of moment closure is central to the study of multitype stochastic population dynamics since equations for moments up to a given order will generally involve higher-order moments. To obtain a Normal approximation, the standard approach is to replace third- and higher-order moments by zero, which may be severely restrictive on the structure of the p.d.f. The purpose of this paper is therefore to extend the univariate truncated saddlepoint procedure to multivariate scenarios. This has several key advantages: no distributional assumptions are required; it works regardless of the moment order deemed appropriate; and, we obtain an algebraic form for the associated p.d.f. irrespective of whether or not we have complete knowledge of the cumulants. The latter is especially important, since no families of distributions currently exist which embrace all cumulants up to any given order. In general the algorithm converges swiftly to the required p.d.f.; analysis of a severe test case illustrates its current operational limit.
journal_name
Math Bioscijournal_title
Mathematical biosciencesauthors
Renshaw Edoi
10.1016/s0025-5564(00)00037-7subject
Has Abstractpub_date
2000-11-01 00:00:00pages
57-75issue
1eissn
0025-5564issn
1879-3134pii
S0025-5564(00)00037-7journal_volume
168pub_type
杂志文章abstract：:We apply to Michaelis-Menten kinetics an alternative approach to the study of Singularly Perturbed Differential Equations, that is based on the Renormalization Group (SPDERG). To this aim, we first rebuild the perturbation expansion for Michaelis-Menten kinetics, beyond the standard Quasi-Steady-State Approximation (s...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2017.11.012
更新日期：2018-05-01 00:00:00
abstract：:An inherent problem in studying the behavior of a metabolic pathway is the impossibility of developing a complete, detailed model that includes all the cellular processes that have an impact on the set of fluxes in such a pathway. Lacking this, one requires some means of modeling the interactions between a metabolic p...
journal_title：Mathematical biosciences
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doi：10.1016/0025-5564(90)90049-5
更新日期：1990-06-01 00:00:00
abstract：:General nonstationary birth-death process with possible catastrophes on finite state space is studied. The approach for obtaining the bounds on the rates of convergence to the limiting characteristics is outlined. Method for construction of the limiting characteristics is proposed. We also show that, as a rule, the in...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2013.02.009
更新日期：2013-09-01 00:00:00
abstract：:We consider a host-parasitoid system with individuals moving on a square grid of patches. We study the effects of increasing movement frequency of hosts and parasitoids on the spatial dynamics of the system. We show that there exists a threshold value of movement frequency above which spatial synchrony occurs and the ...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2006.03.019
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abstract：:It is well known that in the most general epidemic models with multiple pathogen variants a competitive exclusion principle is valid, such that the variant with the highest reproduction number eliminates the rest. Mechanisms such as super-infection, coinfection, and cross-immunity can lead to pathogen polymorphism whe...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2006.09.010
更新日期：2007-05-01 00:00:00
abstract：:This study is a theoretical excursion into gravity models and their usability in evaluating importance of spatial structure and population development for the spread of colonizing organisms. A so called "gravity score" for sites is deduced, and such a score could be used for predicting risk of colonization once one si...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2009.08.008
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journal_title：Mathematical biosciences
pub_type： 杂志文章
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abstract：:A stochastic epidemic model is formulated for the study of the protective effects of vaccination in a population that is stratified by vaccine-related factors. The epidemic model is transformed into a counting process, and then martingale-based methods are used to provide estimators of vaccine efficacy and their varia...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/0025-5564(93)90028-9
更新日期：1993-09-01 00:00:00
abstract：:Subterranean termites live in large colonies under the ground where they build an elaborate network of tunnels for foraging. In this study, we explored how the termite population size can be estimated using partial information on tunnel patterns. To achieve this, we used an agent-based model to create tunnel patterns ...
journal_title：Mathematical biosciences
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doi：10.1016/j.mbs.2019.108218
更新日期：2019-09-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2016.11.004
更新日期：2017-02-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2004.03.001
更新日期：2004-07-01 00:00:00
abstract：:The problem of biological invasion in a model single-species community is considered, the spatiotemporal dynamics of the system being described by a modified Fisher equation. For a special case, we obtain an exact solution describing self-similar growth of the initially inhabited domain. By comparison with numerical s...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(01)00068-2
更新日期：2001-08-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2008.02.004
更新日期：2008-05-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(96)00115-0
更新日期：1997-01-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2009.03.001
更新日期：2009-06-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/0025-5564(95)00049-6
更新日期：1996-03-01 00:00:00
abstract：:A pandemic of a novel Coronavirus emerged in December of 2019 (COVID-19), causing devastating public health impact across the world. In the absence of a safe and effective vaccine or antivirals, strategies for controlling and mitigating the burden of the pandemic are focused on non-pharmaceutical interventions, such a...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2020.108364
更新日期：2020-07-01 00:00:00
abstract：:Frailty models are becoming increasingly popular in multivariate survival analysis. Shared frailty models in particular are often used despite their limitations. To overcome their disadvantages numerous correlated frailty models were established during the last decade. In the present study, we examine bivariate correl...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2004.11.010
更新日期：2005-11-01 00:00:00
abstract：:In a previous paper we studied the spread of excitation in a simplified model of the left ventricle, affected by fiber structure and obliqueness, curvature of the wall and Purkinje network. In the present paper we investigate the extracellular potential distribution u in the same ventricular model. Given the transmemb...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(98)10004-4
更新日期：1998-07-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2014.09.005
更新日期：2015-02-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2014.02.007
更新日期：2014-05-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(99)00027-9
更新日期：1999-08-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2010.06.002
更新日期：2010-09-01 00:00:00
abstract：:A multicompartmental model is proposed to deal with the spread of the HIV epidemic. Stratification with respect to high- and low-risk groups is taken into account, introducing a "fuzzy" decomposition of the compartment of susceptibles. The infectivity period is staged using different levels of CD4 cell counts. Asympto...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/0025-5564(91)90021-a
更新日期：1991-12-01 00:00:00
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journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(02)00085-8
更新日期：2002-05-01 00:00:00
abstract：:Traits such as skill at foraging and investment in anti-predator defense may vary among individuals within a species population. This intraspecific variation has implications for community dynamics. The implications of intraspecific variation of a consumer in the intermediate level of a tritrophic food chain are explo...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2013.04.008
更新日期：2013-08-01 00:00:00
abstract：:We present an axiomatic approach for multilocus informativeness measures for determining the amount of information that a set of polymorphic genetic markers provides about individual ancestry. We then reveal several surprising properties of a decision-theoretic based measure that is consistent with the set of proposed...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2018.10.011
更新日期：2018-12-01 00:00:00
abstract：:Inflammation plays a critical role in the development and progression of cancer, evident in multiple patient populations manifesting increased, non-resolving inflammation, such as inflammatory bowel disease, viral hepatitis and obesity. Given the complexity of both the inflammatory response and the process of oncogene...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2014.07.009
更新日期：2015-02-01 00:00:00
abstract：:Some viruses encode proteins that promote cell proliferation while others, such as the human immunodeficiency virus (HIV), encode proteins that prevent cell division. It has been hypothesized that the selective advantage determining which strategy evolves depends on the ability of the virus to induce a cellular enviro...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/s0025-5564(00)00020-1
更新日期：2000-07-01 00:00:00
abstract：:A three-dimensional diffusion model with either hexagonal or cylindrical symmetry has been constructed to simulate desorption profiles of hydrophilic chemicals from the topmost layer of human skin (the stratum corneum) as measured in ex vivo studies. The tissue is pierced by skin appendages - sweat glands and hair fol...
journal_title：Mathematical biosciences
pub_type： 杂志文章
doi：10.1016/j.mbs.2018.03.010
更新日期：2018-06-01 00:00:00
