Dynamics of vaccination in a time-delayed epidemic model with awareness.

Abstract:

:This paper investigates the effects of vaccination on the dynamics of infectious disease, which is spreading in a population concurrently with awareness. The model considers contributions to the overall awareness from a global information campaign, direct contacts between unaware and aware individuals, and reported cases of infection. It is assumed that there is some time delay between individuals becoming aware and modifying their behaviour. Vaccination is administered to newborns, as well as to aware individuals, and it is further assumed that vaccine-induced immunity may wane with time. Feasibility and stability of the disease-free and endemic equilibria are studied analytically, and conditions for the Hopf bifurcation of the endemic steady state are found in terms of system parameters and the time delay. Analytical results are supported by numerical continuation of the Hopf bifurcation and numerical simulations of the model to illustrate different types of dynamical behaviour.

journal_name

Math Biosci

journal_title

Mathematical biosciences

authors

Agaba GO,Kyrychko YN,Blyuss KB

doi

10.1016/j.mbs.2017.09.007

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

92-99

eissn

0025-5564

issn

1879-3134

pii

S0025-5564(17)30075-5

journal_volume

294

pub_type

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