Abstract：
:A novel multi-input single output (MISO) black-box sigmoid model is developed to simulate the biosorption of heavy metal cations by the fission yeast from aqueous medium. Validation and verification of the model is done through statistical chi-squared hypothesis tests and the model is evaluated by uncertainty and sensitivity analyses. The simulated results are in agreement with the data of the studied system in which Schizosaccharomyces pombe biosorbs Ni(II) cations at various process conditions. Experimental data is obtained originally for this work using dead cells of an adapted variant of S. Pombe and represented by Freundlich isotherms. A process optimization scheme is proposed using the present model to build a novel application of a cost-merit objective function which would be useful to predict optimal operation conditions.
journal_name
Math Bioscijournal_title
Mathematical biosciencesauthors
Özen R,Sayar NA,Durmaz-Sam S,Sayar AAdoi
10.1016/j.mbs.2015.04.007subject
Has Abstractpub_date
2015-07-01 00:00:00pages
40-6eissn
0025-5564issn
1879-3134pii
S0025-5564(15)00088-7journal_volume
265pub_type
杂志文章abstract：:A three-dimensional diffusion model with either hexagonal or cylindrical symmetry has been constructed to simulate desorption profiles of hydrophilic chemicals from the topmost layer of human skin (the stratum corneum) as measured in ex vivo studies. The tissue is pierced by skin appendages - sweat glands and hair fol...
journal_title：Mathematical biosciences
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journal_title：Mathematical biosciences
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pub_type： 杂志文章
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journal_title：Mathematical biosciences
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journal_title：Mathematical biosciences
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journal_title：Mathematical biosciences
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journal_title：Mathematical biosciences
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journal_title：Mathematical biosciences
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journal_title：Mathematical biosciences
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