Abstract:
:Although alpha 1-antitrypsin deficiency has been associated with obstructive lung disease in individuals possessing a homozygous phenotype (PiZZ), this association has not been as clearly documented in heterozygous individuals (PiMZ, PiMS, and PiSZ phenotypes). Information regarding the heterozygous adolescent population is particularly lacking, making the evaluation and treatment of such patients difficult. We present the case of an adolescent with a history of asthma and heterozygous (PiSZ) alpha 1-antitrypsin deficiency and outline our management with reference to appropriate literature.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Nuckton TJ,Beckerman RCdoi
10.1097/00007611-199610000-00018subject
Has Abstractpub_date
1996-10-01 00:00:00pages
1011-3issue
10eissn
0038-4348issn
1541-8243journal_volume
89pub_type
杂志文章,评审abstract:OBJECTIVE:This study compares the primary health care quality of community health centers (CHCs) and health maintenance organizations (HMOs) in South Carolina to elucidate the quality of CHC performance relative to mainstream settings such as the HMO. METHODS:Mail surveys were used to obtain data from 350 randomly sel...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000066811.53167.2E
更新日期:2003-08-01 00:00:00
abstract::The vast majority of acute iron toxicity cases occur in children less than 5 years of age. Moreover, clinical hepatic injury is uncommon with most symptoms stemming from the intestinal tract (eg, nausea, vomiting, diarrhea). Therefore, physicians, particularly those who do not routinely treat pediatric patients, are o...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000152546.05519.FE
更新日期:2005-02-01 00:00:00
abstract::We have described clostridial sepsis in a child who presented with an abdominal crisis of sickle cell disease. Clostridium paraputrificum should be included in the list of organisms known to cause sepsis in patients with sickle cell anemia. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198012000-00033
更新日期:1980-12-01 00:00:00
abstract:OBJECTIVES:This study evaluated the role of ankle-brachial index (ABI) as an effective screening test of coronary artery disease (CAD) in the Hispanic population. METHODS:This was an observational cross-sectional study, based on a retrospective review of the medical management of the study patients using already avail...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e318189aabc
更新日期:2008-11-01 00:00:00
abstract::Each year an estimated 1.3 million Americans suffer eye injuries. There is little information in the literature regarding the prevalence, demographic characteristics, and prognosis of these patients. The Eye Injury Registry of Alabama (EIRA) serves as the first and only statewide system of its kind for the collection ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198707000-00004
更新日期:1987-07-01 00:00:00
abstract::Reported is a case of mesenteric venous thrombosis occurring in a 46-year-old woman who had taken an oral contraceptive for six years. Seventeen cases of mesenteric venous thrombosis have been reported in young women taking oral contraceptives. An association between oral contraceptive agents and mesenteric venous thr...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197703000-00033
更新日期:1977-03-01 00:00:00
abstract::A 54-year-old woman, perhaps the oldest living American black with homozygous beta thalassemia, has had a relatively benign clinical course since her case was first reported two decades ago. Despite progressive splenomegaly, she has remained active without blood transfusions. This case emphasizes the mildness of homoz...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197609000-00041
更新日期:1976-09-01 00:00:00
abstract:BACKGROUND:Pulmonary contusion (PC) is the most common injury identified in pediatric blunt chest trauma. The disagreement over management principles of children with PC may complicate care of these patients. METHODS:We reviewed the literature and our institutional experience. RESULTS:Pulmonary contusion is most ofte...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199812000-00002
更新日期:1998-12-01 00:00:00
abstract::Of five patients with hypernephroma who were maintained on hemodialysis after nephrectomy, four died with metastic disease after having been on hemodialysis for an average of 13.7 months (range 8 to 19). The fifth patient had no evidence of malignancy after 21 months of dialysis; he then received a renal allograft fro...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197908000-00019
更新日期:1979-08-01 00:00:00
abstract::A three-year prospective study during the entire course of preventive therapy with isoniazid (INH) for recently infected hospital employees was undertaken to evaluate the risk of developing INH-related hepatic injury. Results of clinical and laboratory tests at 1, 2, 6, and 12 months were correlated to ascertain the s...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197702000-00009
更新日期:1977-02-01 00:00:00
abstract::Potentially serious iatrogenic hand injuries occurred in three patients in a general medicine practice. All resulted from technologic advances in patient care. Each resulted in substantial economic and emotional costs. One patient sustained a serious residual disability. Such injuries have rarely been reported in the ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198612000-00011
更新日期:1986-12-01 00:00:00
abstract::A 42-year-old woman had dysentery caused by the Shiga bacillus, Shigella dysenteriae type 1, while taking diphenoxylate with atropine during and after her return from a trip to Mexico. Although she was treated with appropriate antibiotics, she suffered a prolonged and toxic acute course followed by intermittent bouts ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198003000-00034
更新日期:1980-03-01 00:00:00
abstract::A phase II study of doxorubicin (Adriamycin)-based induction chemotherapy followed by cyclophosphamide/BCNU (CyBCNU) intensification and autologous bone marrow transplantation (ABMT) was conducted in 20 consecutive women with hormone-resistant metastatic breast cancer referred to our center. Of these 20 women, aged 24...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:10.1097/00007611-199503000-00015
更新日期:1995-03-01 00:00:00
abstract::The term "top of the basilar" has been used in reference to a group of signs and symptoms of midbrain, diencephalic, and posteroinferior hemispheric dysfunction. It has been attributed to ischemia in the territory of second- and third-order vessels that arise from the uppermost portion of the basilar artery. We report...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198807000-00009
更新日期:1988-07-01 00:00:00
abstract:BACKGROUND:Hepatitis secondary to infection with the hepatitis C virus (HCV) is one of the most common causes of viral hepatitis worldwide. Multiple extrahepatic manifestations of HCV infection have been recognized. Dilated and hypertrophic cardiomyopathy associated with HCV infection have been recently described in th...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31822462e2
更新日期:2011-08-01 00:00:00
abstract::Since April 1975, 292 patients have had gastric operations for morbid obesity: gastric bypass with Roux-en-Y gastrojejunostomy (RY), 105 patients; gastric bypass with loop gastrojejunostomy (loop), 69 patients; greater curvature gastroplasty, 40 patients; and gastric partition with gastrogastrostomy, 78 patients. Foll...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198211000-00005
更新日期:1982-11-01 00:00:00
abstract::Multiple sclerosis (MS) is among the most crippling diseases of the nervous system in young adults, and diagnosis can be difficult. It is true that MS can exist without magnetic resonance imaging or cerebrospinal fluid abnormalities, but whenever there are an atypical clinical pattern and no confirmatory laboratory te...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199603000-00008
更新日期:1996-03-01 00:00:00
abstract::HBsAg and anti-HBs positivity was determined in hospital laboratory workers and nonlaboratory hospital workers (controls) matched for race and sex and adjusted for age. The combined prevalence of antigen-antibody positivity among white female technicians was 12% versus 0 of controls (P less than 0.005). The highest pr...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197709000-00020
更新日期:1977-09-01 00:00:00
abstract::To determine sensitivity and specificity of magnetic resonance imaging (MRI) and ultrasonography (US) in the detection of breast implant rupture, and also to determine the relative merits of clinical examination and mammography, we studied 81 patients (160 implants). All patients had implants removed, thus allowing co...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199604000-00009
更新日期:1996-04-01 00:00:00
abstract::We have described a patient with unilateral adrenal hyperplasia, a rare cause of primary aldosteronism, and reviewed the literature on this subject. The treatment of this disorder appears to be surgical. Whether its pathogenesis is related to the more common varieties of primary aldosteronism is open to speculation. ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198901000-00021
更新日期:1989-01-01 00:00:00
abstract::We have described a 38-year-old woman with a lesion of the cervix found on routine physical examination. The lesion proved to be a primary leiomyosarcoma of the cervix. Despite radiation therapy, surgery, and chemotherapy, the tumor recurred and grew relentlessly. She is alive with disease at two years seven months af...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198104000-00042
更新日期:1981-04-01 00:00:00
abstract:OBJECTIVES:To evaluate the real-world use of various weight loss techniques and to compare the effectiveness of nontraditional methods with diet and exercise in helping nongeriatric adults lose weight. METHODS:A cross-sectional analysis of the 2005-2010 National Health and Nutrition Examination Survey was performed. A...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000130
更新日期:2014-07-01 00:00:00
abstract::Rapid loss of erythrocyte galactose-1-phosphate uridyl transferase in hemolysates from an infant 26 days after transfusion led to investigation of the possiblity of an unstable enzyme or other variant of galactosemia. However, the child was found to have the classic type of galactosemia. The seeming transferase instab...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197503000-00010
更新日期:1975-03-01 00:00:00
abstract::In a community hospital, we correlated results of thallium 201 myocardial scintigraphy with coronary arteriographic data in 79 patients. Scintigraphy was 92% sensitive and 85% specific in detecting coronary artery disease. There were no false-negative scintigrams in patients with double or triple vessel disease. The m...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198408000-00014
更新日期:1984-08-01 00:00:00
abstract::We reviewed the records of patients with cecal volvulus at three affiliated hospitals of Eastern Virginia Medical School to elucidate its incidence, patterns of presentation, and current methods of surgical management. We identified 109 patients in whom a discharge diagnosis of intestinal obstruction due to volvulus w...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1988-10-01 00:00:00
abstract::Skin and soft tissue necrosis is an uncommon but increasingly recognized complication of coumarin anticoagulant therapy. A patient is described with extensive involvement of all four extremities and the nose, requiring amputation of three extremities. The characteristic clinical features of the disorder are reviewed, ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198011000-00015
更新日期:1980-11-01 00:00:00
abstract:OBJECTIVES:This study describes the clinical problems and psychiatric diagnoses of college students who sought services at a student counseling clinic and were subsequently referred for evaluation by a psychiatrist. Several important psychiatric problems present before leaving for college that could mandate the selecti...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000001089
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) was investigated at a tertiary care hospital, and relationship was made between the clinical and genetic definitions of community- and healthcare-associated MRSA. METHODS:Nonduplicate isolates of S. aureus were collected during 2004. Iso...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31815d3fce
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:The number of methicillin-resistant STaphylococcus aureus (MRSA) infections in the hospital setting is increasing but little is known of its prevalence in the community. In a 1986-1987 study, the prevalence in dermatology outpatient clinics was <0.9%. This study reports changes in the same facilities from 19...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199804000-00011
更新日期:1998-04-01 00:00:00
abstract::To understand fully a physician's role in society, and to deal successfully with the current sense of crisis, the medical profession must evolve a world-view that appropriately relates a physician to the patient, to the practice environment, to the base of knowledge, and to the physician's own sense of self. Such a wo...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198812000-00022
更新日期:1988-12-01 00:00:00