Abstract:
BACKGROUND:The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) was investigated at a tertiary care hospital, and relationship was made between the clinical and genetic definitions of community- and healthcare-associated MRSA. METHODS:Nonduplicate isolates of S. aureus were collected during 2004. Isolates were classified clinically as community-associated (CA) or healthcare-associated (HA). Molecular typing studies were performed on the isolates. RESULTS:Four hundred and two S. aureus isolates were collected, of which 281 (70%) were MRSA. By clinical definition, 58 (21%) were classified as CA-MRSA and 215 (77%) as HA-MRSA. Among CA-MRSA, 36 (62%) harbored a SCCmec type IV gene. None of the SCCmec type IV CA-MRSA expressed inducible clindamycin resistance (MLSBi). Among 57 HA-MRSA isolates, 31 (54.4%) harbored a SCCmec type IV gene; MLSBi present in 5 (16%). Type IV SCCmec MRSA were most often associated with skin and soft tissue infections (RR 3.34 95% CI 1.43, 7.8). USA300 was the most common genotype among both CA- and HA-MRSA. CONCLUSIONS:Community-associated MRSA is a prominent pathogen with its most common genotype, USA300, representing a significant proportion of CA- and HA-MRSA infections in our institution. Clinical definitions of CA- and HA- status do not correlate well with the genetic definitions, particularly for HA-MRSA.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Patel M,Hoesley CJ,Moser SA,Stamm AM,Baddley JW,Waites KBdoi
10.1097/SMJ.0b013e31815d3fcesubject
Has Abstractpub_date
2008-01-01 00:00:00pages
40-5issue
1eissn
0038-4348issn
1541-8243pii
00007611-200801000-00018journal_volume
101pub_type
杂志文章abstract::Preventive screening measures for low back pain are limited. Despite considerable evidence that anatomic narrowing of the lumbar spinal canal is a risk factor for specific back problems, difficulty in measuring the canal without unacceptable radiation exposure, cost, or discomfort has limited the assessment of its cli...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198908000-00012
更新日期:1989-08-01 00:00:00
abstract::Giant cell arteritis has been thought to occur only in white patients. There have been several recent reports of this disorder to blacks, however, and this case of biopsy-proven giant cell arteritis in a black patient indicates the diagnosis should be considered in any elderly patient with typical symptoms regardless ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197909000-00045
更新日期:1979-09-01 00:00:00
abstract::Although skin testing with ubiquitous antigens is widely employed to assess delayed hypersensitivity, little is known about the effect of geographic location on the frequency of skin test reactions to given antigens. To assess skin test reactivity in the mid-South, 82 hospitalized patients and 68 normal controls had s...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197604000-00013
更新日期:1976-04-01 00:00:00
abstract::Primary sarcomatous arterial tumors are rare. We have reported a case of malignant fibrous histiocytoma in an elderly woman successfully treated by resection of the involved femoral vessel and reconstruction with a PTFE graft. The long-term result in this patient is presently uncertain. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199202000-00030
更新日期:1992-02-01 00:00:00
abstract::Thirteen male patients consecutively admitted to an inpatient drug and alcohol rehabilitation hospital with the primary diagnosis of crack cocaine dependence were shown a 30-minute videotape that included salient environmental cues intended to elicit cocaine craving. The subjects were tested before and after the video...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199411000-00016
更新日期:1994-11-01 00:00:00
abstract::Melatonin, a hormone produced by the pineal gland, may be a promising treatment option for tinnitus. The primary functions of this hormone are believed to be the initiation and maintenance of sleep because its secretions coincide with circadian rhythms. Some investigators have noted that melatonin may alleviate subjec...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.14423/01.SMJ.0000450714.38550.d4
更新日期:2014-06-01 00:00:00
abstract::Patent ductus arteriosus (PDA) is a malady usually identified during childhood. Prompt surgical correction provides definitive therapy with long-term survival. When not corrected, PDA leads to significant morbidity and mortality, making it a rare condition in the adult population. We report the case of a 44-year-old m...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2001-03-01 00:00:00
abstract::Undocumented patient information in the medical record (MR) is a barrier to providing high quality care. Inadequate documentation has recently been reported for two cardiovascular diseases. This study was designed to evaluate the documentation of asthma management in the MR to determine if it is consistent with the NI...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31819ecb03
更新日期:2009-05-01 00:00:00
abstract::Pulmonary arterial hypertension (PAH), a rare disease involving the pulmonary vascular circuit, is defined as an elevation in pulmonary arterial pressures and is characterized by symptoms of dyspnea, chest pain, and syncope. If left untreated, the disease carries a high mortality rate, with the most common cause of de...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e31802f2ff1
更新日期:2007-04-01 00:00:00
abstract::Treatment of major abdominal vascular injuries is a challenge. Since 1973, 93 patients have been treated at our institution for 147 abdominal vascular injuries. The majority of these injuries (67%) resulted from penetrating trauma in young men between 21 and 30 years of age. Upon admission 72% of the patients were in ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198510000-00003
更新日期:1985-10-01 00:00:00
abstract::We compared a "cardiac profile" test with standard creatine kinase (CK) and lactic dehydrogenase (LD) electrophoresis in 798 cases of possible acute myocardial infarction (MI). The cardiac profile enzyme screen (CK-B, CK, LD) used on 495 patients who came to the emergency department with chest pain suggestive of acute...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:1989-09-01 00:00:00
abstract::Poisoning by antimony led to the death of a great individual in English literature. This case report gives as much of the history of the illness as can be found and tells a little about the individual. ...
journal_title:Southern medical journal
pub_type: 传,历史文章,杂志文章
doi:10.1097/00007611-198205000-00021
更新日期:1982-05-01 00:00:00
abstract::Symptoms of hyperphosphatemia usually relate to the associated hypocalcemia. In a 33-year-old patient accidental infusion of a bolus of potassium phosphate (5 ml intravenously) was immediately followed by cardiac arrest. During CPR, clinically important hypocalcemia or hyperkalemia was not detected, but serum phosphor...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1988-08-01 00:00:00
abstract::Twelve cases of Shigella sonnei infection, with two deaths, occurred at a custodial institution in Donelson, Tennessee, in April and May 1973. Nine of the cases and both deaths were in patients hospitalized at the institution's infirmary. The patients with nosocomial shigellosis were significantly younger and had been...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197610000-00026
更新日期:1976-10-01 00:00:00
abstract::Proximal gastric vagotomy is a useful operation for duodenal ulcer disease that is intractable to medical management. It is also useful in selected patients with acute duodenal ulcer perforation. We present an overview of the indications for proximal gastric vagotomy, along with its results. The major benefits of prox...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198906000-00014
更新日期:1989-06-01 00:00:00
abstract::In the past 30 years there has been no improvement in the five-year survival rate for endometrial carcinoma. Any change comparable to improved survival in cervical carcinoma will be accomplished only by similar detection of the early asymptomatic and precursor lesions of endometrial carcinoma. Reasons why the conventi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198004000-00022
更新日期:1980-04-01 00:00:00
abstract::In children, intramural duodenal hematomas resulting from blunt abdominal trauma are generally managed nonoperatively with nasogastric suction and parenteral nutrition. Experience with three cases in which this form of treatment failed caused us to reappraise its benefits and results. Consequently, we now recommend su...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198808000-00011
更新日期:1988-08-01 00:00:00
abstract::A 30-year-old man had endocarditis and hip arthritis associated with the recently recognized fungus, Scedosporium inflatum. Inhibition, and possibly cure, of endocarditis occurred with medical therapy alone. Data from in vitro susceptibility testing did not predict clinical response. This case also illustrates the nee...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199008000-00025
更新日期:1990-08-01 00:00:00
abstract::Narcolepsy is a severely debilitating neurologic disease that is not as rare as many believe, affecting an estimated 140,000 Americans. Despite the sometimes debilitating nature of narcolepsy symptoms, the disease may go undiagnosed without an organized method for evaluating patients with sleep complaints. Many of the...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.smj.0000056655.15660.42
更新日期:2003-03-01 00:00:00
abstract::This article reviews the epidemiology of weight gain and diabetes mellitus in general and in patients with severe mental illness in particular. Body mass index is defined, and possible predictors for weight gain in patients receiving antipsychotic medications are also enumerated. Information on risk of association wit...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.smj.0000167621.49292.11
更新日期:2005-07-01 00:00:00
abstract::A retrospective study of 45 patients hospitalized with blastomycosis of bones or joints revealed 41 cases of osteomyelitis and 12 cases of septic arthritis. The majority were men (35 [78%] patients) and non-Aboriginal (32 [71%] patients). Median time from the onset of symptoms to hospitalization was shorter in women t...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3180487a92
更新日期:2007-06-01 00:00:00
abstract::Phenformin-associated lactic acidosis is an important though unusual cause of acute abdominal pain. Its clinical picture suggests other catastrophic abdominal entities. A representative case is presented. Aids to arriving at this diagnosis are presented and the specific therapy is outlined. The pathophysiology of this...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197803000-00039
更新日期:1978-03-01 00:00:00
abstract:OBJECTIVES:Hematological malignancies of the breast share a presentation similar to primary breast carcinomas but differ substantially in therapeutic approach and clinical outcomes. In this study, we investigate the frequency of hematological malignancies, their relative primary and secondary occurrences, and further c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000710
更新日期:2017-10-01 00:00:00
abstract::The Pelorus Stereotactic Surgical System is a relatively new, commercially available device that can be used to perform computed tomography (CT)-guided stereotactic brain biopsy. It has been promoted as being a relatively simple and inexpensive system that is more rapid, less cumbersome, and generally easier to use th...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199307000-00008
更新日期:1993-07-01 00:00:00
abstract::We have reported a case of horseshoe kidney, a common renal fusion anomaly. Because of the 25% incidence of associated genitourinary anomalies, we believe that the diagnosis of horseshoe kidney in pediatric patients should initiate a thorough urologic evaluation, including intravenous urography and real-time sonograph...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198502000-00021
更新日期:1985-02-01 00:00:00
abstract::Prosthetic joint infection with Mycobacterium tuberculosis usually involves the hips or knees and can result from either local reactivation, or less often from hematogenous spread. Predisposing conditions include rheumatoid arthritis, chronic steroid use and pulmonary diseases. The most common symptom at presentation ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000232972.50186.4c
更新日期:2007-01-01 00:00:00
abstract::We retrospectively analyzed experience with total gastrectomy (TG) for gastric carcinoma in 23 patients. The TNM stage was I in one patient, II in one patient, III in eight patients, and IV in 13. Linitis plastica was found in ten patients. The operation was considered curative in only eight patients (35%). There were...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198908000-00011
更新日期:1989-08-01 00:00:00
abstract::Hypothyroidism is a common condition. Rarely, it may occur in combination with autoimmune failure of other endocrine glands (autoimmune polyendocrinopathy syndrome type 2, previously known as Schmidt's syndrome). In such cases, restoring normal thyroid function may precipitate adrenal failure. Clinicians should have a...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000056647.58668.CD
更新日期:2003-08-01 00:00:00
abstract::A combined patient flow and work sampling study was done at the Ambulatory Pediatric Service of the Medical University of South Carolina. The biggest problem was that almost two thirds of the patient's time was spent waiting to see the doctor. Reasons for delay included too few examining rooms, the single block appoin...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197706000-00004
更新日期:1977-06-01 00:00:00
abstract::Recent investigations of outbreaks of Salmonella enteritidis gastroenteritis among humans, especially in the northeastern United States, implicate grade A shell chicken eggs as the likely vehicle of transmission. In April 1991 we investigated an outbreak of S enteritidis infections after a wedding anniversary celebrat...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199312000-00005
更新日期:1993-12-01 00:00:00