Timing and outcomes for radical cystectomy in nonmuscle invasive bladder cancer.

Abstract:

PURPOSE OF REVIEW:To provide an overview on the available clinical and pathological factors in high-risk nonmuscle invasive bladder cancer (NMIBC) patients that help to approximate the risk of progression to muscle invasion and identify 'the' patients requiring timely cystectomy. The value of a high-quality transurethral tumor resection is pointed out. Outcomes following radical cystectomy are compared with a primarily bladder preserving strategy. RECENT FINDINGS:Carcinoma in situ within the prostatic urethra of NMIBC patients impacts on patient's outcome. Therefore, biopsies taken from the prostatic urethra improve the initial tumor staging accuracy. Lamina propria substaging may provide more detailed prognostic information. Lympho-vascular invasion within the transurethral resection specimen may help to detect patients who benefit from timely cystectomy. Recent findings from patients undergoing radical cystectomy including super-extended lymphadenectomy for clinically NMIBC confirm the substantial rate (25%) of tumor understaging. The fact that almost 10% were found to harbor lymph node metastases underlines the necessity to perform a meticulous lymphadenectomy in NMIBC patients undergoing radical cystectomy. SUMMARY:High-quality transurethral bladder tumor resection including underlying muscle fibers is of utmost importance. Nevertheless, tumor understaging remains an issue of concern and warrants the value of a second transurethral resection in high-risk NMIBC patients. There is a persisting lack of rigid therapeutic recommendations in patients with high-risk NMIBC. Instead, treatment strategy is based on individual risk factors. However, irrespective of initial treatment strategy, there is a subgroup of high-risk NMIBC patients with progressive disease, leading almost inevitably to death.

journal_name

Curr Opin Urol

authors

Zehnder P,Thalmann GN

doi

10.1097/MOU.0b013e328363e46f

subject

Has Abstract

pub_date

2013-09-01 00:00:00

pages

423-8

issue

5

eissn

0963-0643

issn

1473-6586

journal_volume

23

pub_type

杂志文章,评审
  • Urodynamic assessment of patients with stress incontinence: how effective are urethral pressure profilometry and abdominal leak point pressures at case selection and predicting outcome?

    abstract:PURPOSE OF REVIEW:Disagreement exists as to the extent of evaluation required prior to offering surgical intervention for the treatment of stress urinary incontinence in women. While few would argue that additional information can be gleaned from a properly performed urodynamic investigation, it remains unclear exactly...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200411000-00002

    authors: Lemack GE

    更新日期:2004-11-01 00:00:00

  • Female urinary microbiota.

    abstract:PURPOSE OF REVIEW:The newly discovered female urinary microbiota has the potential to deepen our understanding of urinary tract health and disease, including common lower urinary tract conditions such as urinary incontinence and urinary tract infection. The spectrum of painful bladder disorders and other less common co...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000396

    authors: Mueller ER,Wolfe AJ,Brubaker L

    更新日期:2017-05-01 00:00:00

  • Imaging for urolithiasis: standards, trends, and radiation exposure.

    abstract:PURPOSE OF REVIEW:To discuss current trends in imaging for urolithiasis and review the recent scientific literature surrounding this topic. Specifically, to address the efforts urologist should be making to reduce the use of ionizing radiation and to examine alternatives to computerized tomography (CT) scan in diagnosi...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000241

    authors: Lipkin M,Ackerman A

    更新日期:2016-01-01 00:00:00

  • Trimodal therapy for invasive bladder cancer: is it really equal to radical cystectomy?

    abstract:PURPOSE OF REVIEW:Trimodal therapy (TMT) is considered the most effective bladder-sparing approach for muscle-invasive urothelial carcinoma of the bladder (MIBC) and an alternative to radical cystectomy. The purpose of this article was to review and summarize the current knowledge on the equivalence of TMT and radical ...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000203

    authors: Mathieu R,Lucca I,Klatte T,Babjuk M,Shariat SF

    更新日期:2015-09-01 00:00:00

  • The use of stents in contemporary urology.

    abstract:PURPOSE OF REVIEW:Ureteral stents are a mainstay of today's urological armamentarium. This review critically evaluates the recent literature and provides a concise summary of the use of stents in urology today. While stents are used in many reconstructive urologic procedures, this review focuses on the use of stents in...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200403000-00011

    authors: Chew BH,Knudsen BE,Denstedt JD

    更新日期:2004-03-01 00:00:00

  • Limitations of extracorporeal shock wave lithotripsy.

    abstract:PURPOSE OF REVIEW:Extracorporeal shock wave lithotripsy (ESWL) is the preferred modality for the treatment of renal and upper ureteric calculi. The present review focuses on the limitations of ESWL, where recent developments have tried to identify patients who are unlikely to succeed with ESWL and where improvements in...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e32802b70bc

    authors: Madaan S,Joyce AD

    更新日期:2007-03-01 00:00:00

  • Optimizing safety and accuracy of prostate biopsy.

    abstract:PURPOSE OF REVIEW:The objective of this article is to examine the safety of prostate biopsy and discuss the emerging role of MRI-ultrasound fusion technology in improving diagnostic accuracy. RECENT FINDINGS:Men undergoing prostate biopsy frequently experience minor complications, including hematospermia, hematuria, a...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000310

    authors: Jones TA,Radtke JP,Hadaschik B,Marks LS

    更新日期:2016-09-01 00:00:00

  • Clinical update on testicular microlithiasis.

    abstract:PURPOSE OF REVIEW:Testicular microlithiasis becomes a greater interdisciplinary issue among urologists, andrologists, gynecologists dedicated to reproductive medicine, pediatricians, radiologists and pathologists. Proposed management ranges from benign neglect, instructing self-examination over follow-up once, regular ...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e3283314a1d

    authors: Meissner A,Mamoulakis C,de la Rosette JJ,Pes MP

    更新日期:2009-11-01 00:00:00

  • The devastated bladder outlet: treatment options.

    abstract:PURPOSE OF REVIEW:The purpose of this study is to review and discuss recently published studies of therapeutic options in cases with the combination of severe sphincteric damage and recurrent stricture of the bladder neck or anastomosis in patients with postradical prostatectomy. RECENT FINDINGS:Recent focus has been ...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000185

    authors: Riedmiller H,Kocot A

    更新日期:2015-07-01 00:00:00

  • New devices for kidney stone management.

    abstract:PURPOSE OF REVIEW:The purpose of this review is to summarize recent developments in the array of devices which are commonly used by urologists in the surgical management of kidney stones. To accomplish this goal, an extensive review of recent endourology literature, conference abstracts, and publicly available document...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000710

    authors: Terry RS,Whelan PS,Lipkin ME

    更新日期:2020-03-01 00:00:00

  • Synthetic slings: which material, which approach.

    abstract:PURPOSE OF REVIEW:The success in the use of the tension-free midurethral sling procedures (tension-free vaginal tape, suprapubic arch, transobturator tape) has dramatically altered the approach to the surgical management of stress urinary incontinence in women and marked a resurgence in the use of mesh. We will analyze...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/01.mou.0000232042.95427.9f

    authors: Roth CC,Holley TD,Winters JC

    更新日期:2006-07-01 00:00:00

  • Renal magnetic resonance angiography: an update.

    abstract::Recent developments in renal magnetic resonance angiography have led to a significant improvement in the technical success rate and diagnostic accuracy of the methods. Specifically, three-dimensional contrast-enhanced magnetic resonance angiography methods have been shown to provide a more reliable depiction of renal ...

    journal_title:Current opinion in urology

    pub_type: 杂志文章

    doi:10.1097/00042307-199803000-00006

    authors: Grist TM

    更新日期:1998-03-01 00:00:00

  • Management of urethrovaginal fistulae.

    abstract:PURPOSE OF REVIEW:Urethrovaginal fistulae are a rare condition. It is a conceptual mistake to consider urethrovaginal fistulae to be synonymous with vesicovaginal fistulae. Urethrovaginal fistulae are a different entity requiring special attention and treatment. Due to the wide variety and individuality of the clinical...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e3282feedd4

    authors: Pushkar DY,Sumerova NM,Kasyan GR

    更新日期:2008-07-01 00:00:00

  • Overdetection in screening for prostate cancer.

    abstract:PURPOSE OF REVIEW:To describe mechanisms behind and extent of overdetection in prostate cancer screening as well as possible ways to avoid unnecessary overdiagnosis. RECENT FINDINGS:Overdetection and overtreatment is common in many areas of modern medicine. Current prostate-specific antigen (PSA) testing has resulted ...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000054

    authors: Hugosson J,Carlsson S

    更新日期:2014-05-01 00:00:00

  • Evaluation of obstructed voiding in the female: how close are we to a definition?

    abstract:PURPOSE OF REVIEW:The difficulties of defining and evaluating bladder outlet obstruction (BOO) in the female patient have been described for several years. This review aims to examine recent literature to summarize progress in the area. RECENT FINDINGS:Within the last 2 years, functional causes of female BOO have been...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000182

    authors: Gammie A,Kirschner-Hermanns R,Rademakers K

    更新日期:2015-07-01 00:00:00

  • Management of stones in renal transplant.

    abstract:PURPOSE OF REVIEW:Increasingly, screening of both deceased and living donor organs has led to the early detection of kidney stones prior to donation. A number of transplant recipients will still present with donor-gifted and de-novo stones. A range of treatment modalities is available in the management of renal transpl...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e32835d3097

    authors: Wong KA,Olsburgh J

    更新日期:2013-03-01 00:00:00

  • Development and translation of histotripsy: current status and future directions.

    abstract:PURPOSE OF REVIEW:The aim of this article is to outline the initial development of histotripsy, a noninvasive image-guided focused ultrasound technology that mechanically homogenizes targeted tissues and to describe the results of preclinical translational research directed toward urologic applications. RECENT FINDING...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000001

    authors: Roberts WW

    更新日期:2014-01-01 00:00:00

  • Diagnosis of localized prostate cancer: 10 years of progress.

    abstract::Advances in the diagnosis of early stage disease, and particularly the introduction of prostate-specific antigen (PSA) testing, have had a dramatic effect on the presentation and clinical management of prostate cancer during the past ten years. As a result, there have been significant epidemiological changes in countr...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200007000-00006

    authors: Feneley MR,Partin AW

    更新日期:2000-07-01 00:00:00

  • 3D-printed models and virtual reality as new tools for image-guided robot-assisted nephron-sparing surgery: a systematic review of the newest evidences.

    abstract:PURPOSE OF REVIEW:Nowadays, kidney cancer surgery has been focusing on a patient-tailored management, expanding the indication to nephron-sparing surgery (NSS). Starting from computer tomography images, 3D models can be created, allowing a never experienced before understanding of surgical anatomy. Once obtained the mo...

    journal_title:Current opinion in urology

    pub_type: 杂志文章

    doi:10.1097/MOU.0000000000000686

    authors: Checcucci E,De Cillis S,Porpiglia F

    更新日期:2020-01-01 00:00:00

  • Does benign prostatic hyperplasia treatment with alpha-blockers affect prostate cancer risk?

    abstract:PURPOSE OF REVIEW:To determine whether alpha-blockers, commonly used for the treatment of benign prostatic hyperplasia, are associated with prostate cancer risk. RECENT FINDINGS:Alpha-blockers have been associated with a reduced risk of prostate cancer aggressiveness in some observational studies and an increased risk...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e32835abcf2

    authors: Loeb S,Gupta A,Losonczy L,Tosoian J,Walsh PC

    更新日期:2013-01-01 00:00:00

  • Current status of robotic partial nephrectomy.

    abstract:PURPOSE OF REVIEW:In recent years, robotic partial nephrectomy has emerged as a technique for treatment of small renal masses alongside laparoscopic and open partial nephrectomy. Since this technique is still in a phase of adoption, many technical improvements, alterations and early experiences are published. We aim to...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e32833c7af0

    authors: Van Haute W,Gavazzi A,Dasgupta P

    更新日期:2010-09-01 00:00:00

  • Surgery for urogenital rhabdomyosarcoma.

    abstract::The treatment and prognosis of rhabdomyosarcoma of the urogenital tract have changed dramatically over the past few decades. Until the 1970s radical cystectomy and pelvic exenteration were the only therapeutic options in rhabdomyosarcoma of the bladder/prostate and of the vagina/uterus. Since then, multiagent chemothe...

    journal_title:Current opinion in urology

    pub_type: 社论,评审

    doi:10.1097/00042307-200111000-00001

    authors: Filipas D

    更新日期:2001-11-01 00:00:00

  • The challenge of stress incontinence and pelvic organ prolapse: revisiting biologic mesh materials.

    abstract:PURPOSE OF REVIEW:The present article reviews the history of mesh-related complications and regulations in SUI and POP repair settings, clinical outcomes associated with the use of biologic and synthetic mesh materials, and novel approaches using modified mesh materials. RECENT FINDINGS:Treatment of pelvic floor disor...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000645

    authors: D'Angelo W,Dziki J,Badylak SF

    更新日期:2019-07-01 00:00:00

  • Contemporary management of urethral trauma and the post-traumatic stricture.

    abstract::This review discusses the contemporary management of urethral trauma and post-traumatic urethral strictures occurring in both the anterior and posterior urethra. Experience in the full spectrum of urethral reconstructive procedures is important. The initial management of patients relies upon adequate drainage of the b...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-199905000-00011

    authors: Chapple CR,Png D

    更新日期:1999-05-01 00:00:00

  • Defining high-risk prostate cancer.

    abstract:PURPOSE OF REVIEW:High-risk prostate cancer often represents a lethal disease requiring timely diagnosis and effective therapy. Standardized criteria that define high-risk prostate cancer have yet to be established, rendering the discrimination of high-risk from nonhigh-risk patients a challenge. This review summarizes...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e328361dba6

    authors: Goldberg H,Baniel J,Yossepowitch O

    更新日期:2013-07-01 00:00:00

  • Modern evaluation of lower urinary tract symptoms in 2014.

    abstract:PURPOSE OF REVIEW:To evaluate and present the evidence for the use of different investigation modalities in men with benign prostatic hyperplasia/lower urinary tract symptoms (LUTS) in 2014. RECENT FINDINGS:Cystometry remains the gold standard in differentiating obstructed from nonobstructed men with LUTS. Prostatic u...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000013

    authors: Mangera A,Chapple C

    更新日期:2014-01-01 00:00:00

  • Virtual endoscopy in urology.

    abstract::Recent years have seen notable advances in virtual reality technology and increased interest in potential medical applications. Computed tomography and magnetic resonance imaging data sets, historically viewed as axial images, may now be used to construct a virtual reality endoscopic image, and navigator software syst...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200103000-00010

    authors: Allan JD,Tolley DA

    更新日期:2001-03-01 00:00:00

  • Salvage therapeutic strategies for bacillus Calmette-Guerin failure.

    abstract:PURPOSE OF REVIEW:To give an overview of current options for conservative treatment of patients failing intravesical bacillus Calmette-Guerin (BCG) and to discuss emerging approaches with potential future clinical applications. RECENT FINDINGS:Radical cystectomy is the standard-of-care for patients failing BCG therapy...

    journal_title:Current opinion in urology

    pub_type: 杂志文章

    doi:10.1097/MOU.0000000000000593

    authors: Hassler MR,Shariat SF,Soria F

    更新日期:2019-05-01 00:00:00

  • Impact of the United States Preventive Services Task Force 'D' recommendation on prostate cancer screening and staging.

    abstract:PURPOSE OF REVIEW:In 2012, the United States Preventive Services Task Force (USPSTF) issued a grade 'D' recommendation against the use of routine prostate-specific antigen (PSA)-based screening for any men. This recommendation reflects critical misinterpretations of the available evidence base regarding benefits and ha...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000383

    authors: Eapen RS,Herlemann A,Washington SL 3rd,Cooperberg MR

    更新日期:2017-05-01 00:00:00

  • Carcinoma in situ of the bladder: why is it underdetected?

    abstract:PURPOSE OF REVIEW:The standard diagnosis of carcinoma in situ (CIS) of the bladder, based on white light cystoscopy and urine cytology, is limited because CIS can vary from normal-appearing mucosa to a lesion indistinguishable from an inflammatory process. Intravesical instillation of Bacillus Calmette-Guerin (BCG) rem...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000758

    authors: Subiela JD,Rodríguez Faba Ó,Guerrero-Ramos F,Aumatell J,Breda A,Palou J

    更新日期:2020-05-01 00:00:00