Insight into the genetic epidemiology of coronary heart disease.

Abstract:

:The associations between candidate gene polymorphisms and coronary heart disease (CHD) are complex as a consequence of pleiotropy, variation with age, selection due to the high lethality of the disease, and interactions with other genes and with environmental factors. Identification of the gene variants that contribute to CHD appears possible; this may considerably improve our understanding of the aetiology and mechanisms of this disease. Furthermore, simultaneous analysis of several predisposing alleles may help to identify high-risk individuals.

journal_name

Ann Med

journal_title

Annals of medicine

authors

Cambien F

doi

10.3109/07853899608999109

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

465-70

issue

5

eissn

0785-3890

issn

1365-2060

journal_volume

28

pub_type

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