Effects of osmotic pressure on intrathecal and epidural lidocaine anesthesia.

Abstract:

:Lidocaine (1%), either in plain distilled water or in 10% dextrose, was intrathecally or epidurally administered to urethane-chloralose anesthetized cats. Electrical stimulation was applied to the gracile tract at a cervical level, and the resultant antidromic compound action potentials were recorded from the sural nerve. Lidocaine dissolved in plain distilled water was more effective than lidocaine dissolved in 10% dextrose solution in suppressing the compound action potentials. Lidocaine-free plain distilled water or dextrose solution caused partial suppression of the compound action potentils. The suppression was more marked following plain distilled water application than following application of 5% or 10% dextrose.

journal_name

J Anesth

journal_title

Journal of anesthesia

authors

Minami T,Koyama N,Amakata Y

doi

10.1007/BF02482066

subject

Has Abstract

pub_date

1996-03-01 00:00:00

pages

39-43

issue

1

eissn

0913-8668

issn

1438-8359

journal_volume

10

pub_type

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