Abstract:
:To evaluate the effects of cardiopulmonary bypass (CPB) on the release of polymorphonuclear leukocyte elastase (PMN-E) and postoperative pulmonary function, the perioperative plasma levels of PMN-E in α1-antitrypsin complex (EAC) and hydrogen peroxide concentration in the expired breath were measured in eight patients who underwent cardiac surgery with CPB, and the relationship between EAC levels and the respiratory index (RI) was studied. Although PMN, EAC, and the ratio of EAC to neutrophil (E/N) were elevated significantly after surgery, alveolar-arterial oxygen difference (A-aDO2) and respiratory index (A-aDO2/PaO2) did not change when compared with those of the preoperative period. Hydrogen peroxide concentration in the expired breath also did not change (below 2.5 μmol·l(-1)) during the perioperative period. These results suggest that the elevation of EAC immediately after cardiac surgery using CPB, which lasted less than 2h, was not a cause of postoperative pulmonary disorder. However, there was a significant positive correlation between E/N ratio and respiratory index (r=0.67,P<0.01). Thus excessive release of PMN-E during CPB may be implicated in the etiology of postoperative respiratory dysfunction.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Yusa T,Nohara A,Sunagawa Mdoi
10.1007/BF02479945subject
Has Abstractpub_date
1995-12-01 00:00:00pages
324-8issue
4eissn
0913-8668issn
1438-8359journal_volume
9pub_type
杂志文章abstract:INTRODUCTION:We investigated the continuous infusion rates of rocuronium necessary to obtain the surgical muscle relaxation before, during, and after the Pringle maneuver on patients who underwent hepatectomy. METHODS:Fifteen patients were induced by total intravenous anesthesia with propofol. After obtaining the cali...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章
doi:10.1007/s00540-018-2498-4
更新日期:2018-06-01 00:00:00
abstract::Cardiac surgery-associated acute kidney injury (AKI) is a major health problem that is extremely common and has a significant effect on cardiac surgical outcomes. AKI occurs in nearly 30 % of patients undergoing cardiac surgery, with about 1-2 % of these ultimately requiring dialysis. The development of AKI predicts a...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-012-1523-2
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:The CO(2) reactivity of cortical cerebral vessels and local cortical blood flow (l-CoBF) were evaluated during anesthesia in patients with moyamoya disease who were undergoing revascularization surgery. METHODS:Using laser-Doppler flowmetry, the CO(2) reactivity of cortical cerebral vessels and l-CoBF were mea...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s005400050043
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:To examine the relationships between effect-site concentrations and electroencephalographic parameters after the induction of general anesthesia with midazolam. METHODS:Twenty-four patients with American Society of Anesthesiologists status I or II were randomly allocated to receive either an intravenous (i.v.)...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-010-0907-4
更新日期:2010-06-01 00:00:00
abstract:PURPOSE:In a previous study using the tail-flick test, we found that intracerebroventricular administration of D-serine, an endogenous co-agonist at the glycine sites of N-methyl-D-aspartate (NMDA) receptors, elicited an antinociceptive effect on thermal nociception. The purpose of the present study was to evaluate the...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1708-3
更新日期:2014-04-01 00:00:00
abstract::The antiarrhythmic effect of flecainide acetate (FCN), a newly developed class I antiarrhythmic drug, was evaluated on epinephrine (E)-halothane induced arrhythmias in dogs. The arrhythmogenic dose of E (ADE) under 1% of halothane was significantly increased from 0.71 +/- 0.08 to 1.08 +/- 0.11 and 1.84 +/- 0.23 micro ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054000040303
更新日期:1990-10-01 00:00:00
abstract:PURPOSE:Our purpose was to examine the effect of dexmedetomidine, when used with phenylephrine during cardiopulmonary resuscitation (CPR), on the cerebral and systemic circulations. METHODS:In pentobarbital-anesthetized, mechanically ventilated dogs, we evaluated pial vessel diameters, cerebral oxygen extraction, and ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-006-0402-0
更新日期:2006-01-01 00:00:00
abstract::Fifteen surgical patients received an epidural injection of 12 ml of 1.5% lidocaine through a catheter placed at C7-T1, followed by further injection as required. An intravenous bolus of 0.5 mg of atropine sulfate was administered simultaneously with the initial epidural injection. The high-(HFC: 0.15-0.4 Hz) and low-...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02482031
更新日期:1995-03-01 00:00:00
abstract:PURPOSE:Intravenous infusion of lidocaine attenuates the stress response to surgery. We aimed to evaluate the effects of perioperative lidocaine on the hemodynamic and hormonal responses for cesarean delivery. METHODS:After the gaining of ethical approval, 90 patients scheduled for elective cesarean delivery were rand...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-009-0738-3
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:We hypothesized anterograde amnesia could be predicted by the bispectral index (BIS) during epidural puncture in patients premedicated with intramuscular midazolam. METHODS:We investigated 64 consecutive patients undergoing gynecological laparotomy under general anesthesia combined with epidural anesthesia. Mi...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-009-0748-1
更新日期:2009-01-01 00:00:00
abstract::Although anaphylactoid reactions to local anesthetics are well known, a radioallergosorbent test (RAST) to detect specific drug reagin (IgE) anti-body has not been developed. We established RAST for local anesthetics by using carboxylic acid derivatives of lidocaine, procaine and methylparaben. Serum samples were take...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054090030074
更新日期:1989-03-01 00:00:00
abstract:PURPOSE:In many countries, patients are generally allowed to have clear fluids until 2-3 h before surgery. In Japan, long preoperative fasting is still common practice. To shorten the preoperative fasting period in Japan, we tested the safety and efficacy of oral rehydration therapy until 2 h before surgery. METHODS:T...
journal_title:Journal of anesthesia
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00540-011-1261-x
更新日期:2012-02-01 00:00:00
abstract::Isolated adrenocorticotropic hormone (ACTH) deficiency is an extremely rare disease in which ACTH-producing cells of the pituitary gland are selectively damaged. The resulting decline in ACTH production and secretion results in chronic secondary adrenocortical insufficiency. The patient in this case did not present wi...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1118-3
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:Sevoflurane increases reactive oxygen species (ROS), which mediate cardioprotection against myocardial ischemia-reperfusion injury. Emerging evidence suggests that autophagy is involved in cardioprotection. We examined whether reactive oxygen species mediate sevoflurane preconditioning through autophagy. METHO...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1755-9
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Postanesthetic shivering can be triggered by surgical stress and several aspects of anesthetic management and is frequently preceded by a decrease in peripheral blood flow due to thermoregulatory vasoconstriction. As perfusion index correlates with peripheral blood flow, we examined whether perioperative per...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章
doi:10.1007/s00540-013-1658-9
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:Postoperative sore throat (POST) after general anesthesia with endotracheal intubation is a common and undesirable complication. In this study, we evaluated the combined effects of paracetamol and dexamethasone on the prevention of POST in patients after general anesthesia. METHODS:A total of 226 patients sche...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-017-2411-6
更新日期:2017-12-01 00:00:00
abstract::We report an 83-year-old man with myasthenia gravis (MG) who developed respiratory depression after spinal anesthesia for transurethral laser enucleation of the prostate. He became less responsive after complained of dyspnea, with a decrease of SpO2 to 83% approximately 13 min after intrathecal administration of 0.5% ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02874-9
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:The effect of the Mega Acer kit(@), a new heated and humidified breathing circuit (HHBC) containing a fluid-warming device, was investigated on intraoperative core temperature (T c). METHODS:A total of 102 patients undergoing elective craniotomies were randomly divided into three groups based on the breathi...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-015-1994-z
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:Propofol and ketamine have become progressively popular in electroconvulsive therapy (ECT) anesthesia, although propofol shortened seizure duration and ketamine might cause cardiotoxicity, psychotic episodes, and delayed recovery. Ketofol is a combination of ketamine and propofol, and the current study was desi...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-012-1378-6
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:The recommended method for elucidating the effects of strong ions other than lactate on acid-base balance is to calculate the non-lactate strong ion difference (SIDnl). A relationship between HCO3 (-) and SIDnl in hyperchloremic patients has already been demonstrated; in the present study, the relationships bet...
journal_title:Journal of anesthesia
pub_type: 杂志文章,多中心研究
doi:10.1007/s00540-016-2158-5
更新日期:2016-06-01 00:00:00
abstract::Within continuously controlled limits of cuff pressure, an endotracheal tube cuff made of polyurethane (PU) prevents secretion inflow better than a conventional polyvinylchloride cuff. However, the temperature difference between ventilator gas and the air inside a PU cuff produces condensation droplets that accumulate...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1849-z
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:Remifentanil has been available in Japan for 3 years. The use of this new opioid is considered a useful adjuvant to general anesthesia. Knowing the exact cost-effectiveness of remifentanil should lead to improved anesthetic outcomes with a reasonable cost. METHODS:This single-blinded, prospective, randomized s...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-010-1006-2
更新日期:2010-12-01 00:00:00
abstract:PURPOSE:Dexmedetomidine acts as a selective α2-adrenergic receptor agonist and an imidazoline receptor agonist, both of which are known to affect insulin secretion. Here, we investigated the effects of clinically relevant concentrations of dexmedetomidine on insulin secretion under in vivo conditions. Furthermore, its ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1943-2
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:This study aimed to examine the incidence, case fatality rate, and characteristics of perioperative symptomatic pulmonary thromboembolism (PS-PTE) throughout Japan. METHODS:From 2002 to 2011, confidential questionnaires were mailed annually to all Japanese Society of Anesthesiologists-certified training hospit...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1939-y
更新日期:2015-06-01 00:00:00
abstract::Alveolar capillary dysplasia (ACD), which is a rare and lethal congenital pulmonary anomaly found in newborns, begins its onset or causes deterioration of the infant's condition some time after birth. Various congenital anomalies in combination with ACD have been reported, except for subglottic stenosis. Therefore, we...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-010-1080-5
更新日期:2011-04-01 00:00:00
abstract:PURPOSE:Transthoracic esophagectomy is an invasive surgery, and the excessive surgical stress produces inflammatory cytokines, which provoke acute respiratory distress syndrome (ARDS). Sivelestat sodium hydrate-a selective neutrophil elastase inhibitor-is used to treat or prevent ARDS in patients undergoing esophagecto...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-018-2602-9
更新日期:2019-04-01 00:00:00
abstract::Recently, gastric ultrasonography has been used as a noninvasive portable tool for evaluating gastric content and volume in adults and children. Pediatric patients are not always cooperative, especially younger ones, and it may be difficult to keep them in the appropriate scanning position without sedation. Hence, we ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2204-3
更新日期:2016-10-01 00:00:00
abstract:PURPOSE:Ultrasound (US)-guided continuous interscalene brachial plexus block (CBPB) is known to provide effective pain relief for arthroscopic rotator cuff repair. This study was conducted to compare analgesic efficacy and forearm muscle tone of the basal infusion rate and bolus dose of 0.2 % ropivacaine for US-guided ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-013-1681-x
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:We conducted a survey to clarify the actual circumstances in which the lungs could not be ventilated and the trachea could not be intubated (CVCI). METHODS:A questionnaire was mailed to all the university hospitals in Japan, asking about CVCI they had experienced during induction of anesthesia in 1998, and bef...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-003-0187-3
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:To compare clinical advantages and hemodynamic and respiratory changes during one lung-collapsed ventilation (OLCV) using a double-lumen tube (DLT) or a single-lumen tube (SLT) with intrathoracic CO(2) insufflation, in patients undergoing thoracic sympathectomy (TS) under general anesthesia. METHODS:One hundre...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s540-002-8088-z
更新日期:2002-01-01 00:00:00