Histologic trends in thyroid cancer 1969-1993: a clinico-pathologic analysis of the relative proportion of anaplastic carcinoma of the thyroid.

Abstract:

BACKGROUND:It was observed that new presentations of anaplastic carcinoma of the thyroid had become infrequent in the last two decades. METHODS:All cases of thyroid cancer seen at our centre between 1969-1993 (n = 2921) were classified as papillary 49%, follicular 34%, medullary 7.5%, anaplastic 4.7%, and other 4.8%. The total number of thyroid cancers show a 3.5-fold rise. RESULTS:The differentiated thyroid cancers show a significant rising trend as against the relative proportion of anaplastic carcinoma, which shows a significant decline (P = 0.002). Clinicopathologic data on 124 patients of anaplastic carcinoma revealed 50% patients had either long-standing goitres, previous thyroid abnormalities, or associated differentiated thyroid carcinoma on histology. CONCLUSIONS:The decline in the relative proportion of anaplastic carcinoma may in part be explained by the clinicopathologic findings or it may be attributed to histological reclassification.

journal_name

J Surg Oncol

authors

Agrawal S,Rao RS,Parikh DM,Parikh HK,Borges AM,Sampat MB

doi

10.1002/(SICI)1096-9098(199612)63:4<251::AID-JSO7>

subject

Has Abstract

pub_date

1996-12-01 00:00:00

pages

251-5

issue

4

eissn

0022-4790

issn

1096-9098

pii

10.1002/(SICI)1096-9098(199612)63:4<251::AID-JSO7>

journal_volume

63

pub_type

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