Abstract:
PURPOSE:To evaluate the effectiveness of positron emission tomography (PET) with carbon-11 choline in brain tumor imaging. MATERIALS AND METHODS:A rat glioma cell line (C6) was incubated with C-14 choline; the time course of uptake and metabolism was determined in vitro. C-11 choline was injected intravenously in tumor-bearing rats; the time course of distribution in organs was determined. C-11 choline also was injected intravenously in 20 patients (aged 6-86 years) with brain tumors and two volunteers (aged 38 and 58 years); distribution of the tracer in the brain was determined. Regional cerebral blood flow was measured by using oxygen-15 water on the same day. RESULTS:C-14 choline was metabolized to phosphoryl choline in glioma cells. The uptake of C-11 choline by glioblastoma cells was three to four times higher than that in the rat brain. All brain tumors took up more C-11 choline than did normal brain; thus, brain tumors that were not treated, as well as those that were treated with surgery or radiation therapy, were depicted. The tumor-normal brain uptake ratio of C-11 choline in brain tumor did not correlate with the O-15 water regional blood flow in the corresponding area. CONCLUSION:C-11 choline PET can depict brain tumors effectively. This method was clinically useful in patients who had undergone surgery.
journal_name
Radiologyjournal_title
Radiologyauthors
Shinoura N,Nishijima M,Hara T,Haisa T,Yamamoto H,Fujii K,Mitsui I,Kosaka N,Kondo T,Hara Tdoi
10.1148/radiology.202.2.9015080subject
Has Abstractpub_date
1997-02-01 00:00:00pages
497-503issue
2eissn
0033-8419issn
1527-1315journal_volume
202pub_type
杂志文章相关文献
RADIOLOGY文献大全abstract::A chart for organizing, teaching, and recording the magnetic resonance (MR) pulse sequences used for brain and cervical spine imaging is described. The chart helps document workable sequences and facilitates comparisons between different sequences. It has also been helpful in instructing residents and fellows how to a...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.157.1.4034970
更新日期:1985-10-01 00:00:00
abstract::While computed tomography (CT) is an accepted procedure for investigation of the inferior vena cava (IVC), little attention has been given to its use in IVC thrombosis secondary to proximal extension of thrombi within the lower venous system. Four cases are presented and several advantages of CT over standard contrast...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.140.2.7255720
更新日期:1981-08-01 00:00:00
abstract::Lung scan data from a series of 45 patients receiving thrombolytic therapy were reviewed to determine if any pattern on the pretherapy perfusion lung scans could be identified that predicted response to therapy. A segmental appearance on the pretherapy scans (complete or nearly complete absence of perfusion in a whole...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.174.2.2104990
更新日期:1990-02-01 00:00:00
abstract::Magnetic resonance (MR) imaging of the thyroid was performed with a 1.5-T system and local receiver coil in 19 "healthy" subjects and 34 patients with various focal and diffuse thyroid disorders. The normal gland was typically homogeneous with increased intensity relative to that of muscle on images obtained with long...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.164.2.3602390
更新日期:1987-08-01 00:00:00
abstract:PURPOSE:To quantify tumor perfusion after transcatheter arterial embolization (TAE) with functional computed tomography (CT) and to validate the reproducibility of quantification measurements. MATERIALS AND METHODS:This study was conducted in accordance with an institutional animal care and use committee-approved prot...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2371040526
更新日期:2005-10-01 00:00:00
abstract::The computed tomographic (CT) chest scans of 11 patients who developed respiratory or constitutional symptoms while receiving amiodarone therapy were reviewed. CT findings indicative of significant amiodarone exposure included (a) high-attenuation parenchymal-pleural lesions in eight of the 11 patients (73%), and (b) ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.177.1.2399310
更新日期:1990-10-01 00:00:00
abstract::The theories of decision processes and signal detection provide a framework for evaluation of observer performance. Some radiological procedures involve a search for multiple similar lesions, e.g., plain radiographic examinations for gallstones or pneumoconiosis. Presuming knowledge of the conventional ROC curve for d...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/121.2.337
更新日期:1976-11-01 00:00:00
abstract::Nephrocalcinosis was diagnosed by means of gray-scale somography in a premature infant with severe bronchopulmonary dysplasia. The examination provided a way of localizing faint calcifications seen on a plain abdominal radiograph. ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/128.2.459
更新日期:1978-08-01 00:00:00
abstract::Since two müllerian defects, the septate and bicornuate uteri, are no longer repaired by means of the same operative approach, an accurate preoperative diagnosis of these anomalies is now critical. A septum can be removed by means of hysteroscopic metroplasty. However, repair of a bicornuate uterus still requires abdo...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.172.3.2528160
更新日期:1989-09-01 00:00:00
abstract:PURPOSE:To evaluate fluorine 18 ((18)F) dihydroxyphenylalanine (DOPA) whole-body positron emission tomography (PET) as a biochemical imaging approach for detection of pheochromocytomas. MATERIALS AND METHODS:(18)F DOPA PET and magnetic resonance (MR) imaging were performed in 14 consecutive patients suspected of havin...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2222010622
更新日期:2002-02-01 00:00:00
abstract::Radiology chiefs at hospitals with open heart surgery programs were queried to ascertain both current and desired degrees of participation by radiologists in coronary angiography. While current participation is limited, respondents indicated a desire to achieve increased active participation. Opposition of cardiologis...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/125.2.313
更新日期:1977-11-01 00:00:00
abstract::The relationship between patient waiting time and capacity and utilization is quantified. By deciding upon the average acceptable and maximum allowable waiting times, the required capacity and resulting utilization rate are fixed. The data needed for analysis include waiting time, patient volume, time required for spe...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/130.3.637
更新日期:1979-03-01 00:00:00
abstract::The anterior humeral line is a valuable aid in the search for supracondylar fractures in children. When it is abnormal other signs of fracture should be carefully sought. The AHL was normal in only 5.8% of the cases reviewed (4 of 68 cases). There was other evidence of fracture in each case. Comparison of the AHLs on ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/128.1.145
更新日期:1978-07-01 00:00:00
abstract::A total of 24,560 fetal biparietal measurements were made using the B-scan technique. The increase in biparietal diameter was compared in normal pregnancies, in those complicated by diabetes or toxemia, and in fetuses thought to be small for dates. Only the last of these groups demonstrated a statistically significant...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.137.1.7422840
更新日期:1980-10-01 00:00:00
abstract::Current management of osteoarthritis (OA) is primarily focused on symptom control. Intra-articular corticosteroid (IACS) injections are often used for pain management of hip and knee OA in patients who have not responded to oral or topical analgesics. Recent case series suggested that negative structural outcomes incl...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/radiol.2020200771
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:To evaluate radiologists' performance for determining a distinction between benign and malignant pulmonary nodules on chest radiographs without and with use of a computer-aided diagnosis scheme. MATERIALS AND METHODS:Fifty-three chest radiographs that depicted 31 primary lung cancers and 22 benign nodules were...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2272020498
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:To evaluate the effect of in utero exposure to a single dose of water-soluble intravenous iodinated contrast medium on thyroid function at birth. MATERIALS AND METHODS:This study was approved by the institutional review board, with waiver of consent, and was HIPAA compliant. Maternal and newborn records were r...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.10100163
更新日期:2010-09-01 00:00:00
abstract::Fluoroscopically guided percutaneous needle aspiration of focal pulmonary lesions was performed in 108 presumed infectious episodes in 82 immunocompromised patients in whom prior diagnostic studies, including transtracheal aspiration, were negative to inconclusive. Two-thirds of the lesions were 4 cm or smaller. Singl...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/132.3.563
更新日期:1979-09-01 00:00:00
abstract::A movable carriage was designed and built for a Franklin film changer to facilitate routine serial 2 times magnification. This simple device permits magnification angiography without major equipment purchases or room alterations. ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/117.2.481a
更新日期:1975-11-01 00:00:00
abstract:PURPOSE:To evaluate the clinical relevance of neovascularization diagnosed with power Doppler ultrasonography (US) in Achilles tendons in patients with chronic achillodynia. MATERIALS AND METHODS:Forty consecutive patients (mean age, 52 years; age range, 30-72 years) were examined. US was performed bilaterally and rep...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2272012069
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:To evaluate positron emission tomography (PET) with fluorine-18-labeled fluorodeoxyglucose (FDG) for detection of pancreatic cancer compared with computed tomography (CT) and ultrasonography (US). MATERIALS AND METHODS:Forty patients with suspected pancreatic cancer underwent static PET after intravenous injec...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.192.1.8208970
更新日期:1994-07-01 00:00:00
abstract::Extracranial applications of diffusion-weighted (DW) magnetic resonance (MR) imaging are gaining increasing importance, including in head and neck radiology. The main indications for performing DW imaging in this relatively small but challenging region of the body are tissue characterization, nodal staging, therapy mo...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/radiol.11101821
更新日期:2012-04-01 00:00:00
abstract::Microwave radiometry is a passive and noninvasive technique that allows quick detection of subcutaneous temperature changes. The feasibility of this technique for differentiating normal intravenous infusions of radiographic contrast medium from extravasations of contrast medium was tested in anesthetized dogs. Room-te...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.184.1.1609070
更新日期:1992-07-01 00:00:00
abstract::Bronchial webs are rare lesions which often go unrecognized. The authors describe a patient who presented with right-lower-lobe bronchiectasis and at-electasis secondary to a web in the right-lower-lobe bronchus. This is the first known instance where such a lesion has been demonstrated by bronchography. The etiology ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/121.3.526
更新日期:1976-12-01 00:00:00
abstract::In real-time ultrasound examinations of six women, jets of urine were noted to enter the bladder during the filling phase. The jets appeared at irregular intervals, and each jet lasted from a fraction of a second up to three seconds. The ureters functioned independently of each other. The flow characteristics of the u...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.140.2.7255730
更新日期:1981-08-01 00:00:00
abstract::Six opossums were evaluated as a possible animal model of radiation esophagitis. In a single exposure to the esophagus, four animals received 60Co radiation of various doses; two served as controls. Pre- and postirradiation evaluations using fiberoptic endoscopy, mucosal biopsy, barium esophagography, and manometry we...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/131.3.731
更新日期:1979-06-01 00:00:00
abstract:PURPOSE:To evaluate treatment of osteoid osteoma with computed tomography (CT)-guided percutaneous excision and immediate follow-up scintigraphy. MATERIALS AND METHODS:Sixteen consecutive adolescent and adult patients underwent CT-guided percutaneous excision of a nidus with 14-gauge biopsy cutting needles, with local...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.201.1.8816550
更新日期:1996-10-01 00:00:00
abstract::The American College of Radiology (ACR) convened a "think tank" of experts on aspects of molecular imaging. The purposes of the colloquium were to develop scenarios about how molecular imaging would develop in the future and to make recommendations to the ACR about how to prepare radiologists for this important set of...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2222011530
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:Evaluate effect of prostatic irradiation on erectile function. MATERIALS AND METHODS:Forty-seven male adult rats were divided into three groups according to a single radiation dose to the prostate: control (no irradiation) (n = 15), 1,000 cGy (n = 15), and 2,000 cGy (n = 17). Five months after irradiation, rat...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.195.1.7534430
更新日期:1995-04-01 00:00:00
abstract::A linear-array, silicon pixel detector, capable of counting single photons, was applied to mammography by using a synchrotron radiation beam. Images were obtained of both a mammographic phantom and a breast-tissue sample. The phantom image was acquired with a mean glandular dose of 0.32 mGy. This detector combined wit...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.208.3.9722850
更新日期:1998-09-01 00:00:00