Abstract:
PURPOSE:To evaluate the effect of in utero exposure to a single dose of water-soluble intravenous iodinated contrast medium on thyroid function at birth. MATERIALS AND METHODS:This study was approved by the institutional review board, with waiver of consent, and was HIPAA compliant. Maternal and newborn records were retrospectively reviewed. All pregnant women who underwent multidetector pulmonary computed tomographic angiography because they were suspected of having pulmonary embolism between 2004 and 2008 and newborns resulting from the index pregnancy were included. In all examinations, iohexol was used as the contrast agent. Dose and amount of contrast agent and gestational age at the time of administration of the contrast agent were collected, and thyroxine (T(4)) and thyroid-stimulating hormone (TSH) levels were measured at birth. A total of 344 maternal and 343 newborn records were reviewed. A descriptive analysis was performed, and means, standard deviations, and confidence intervals were reported. RESULTS:Mean gestational age at the time of administration of the contrast material was 27.8 weeks +/- 7.4. The mean dose of total iodine administered was 45,000 mg/L +/- 7321. All newborns had a normal T(4) level at birth; only one newborn had a transiently abnormal TSH level at birth, which normalized at day 6 of life. This newborn was born to a mother who had many drug exposures during pregnancy. CONCLUSION:A single, high-dose in utero exposure to water-soluble, low-osmolar, iodinated intravenous products, such as iohexol, is unlikely to have a clinically important effect on thyroid function at birth.
journal_name
Radiologyjournal_title
Radiologyauthors
Bourjeily G,Chalhoub M,Phornphutkul C,Alleyne TC,Woodfield CA,Chen KKdoi
10.1148/radiol.10100163subject
Has Abstractpub_date
2010-09-01 00:00:00pages
744-50issue
3eissn
0033-8419issn
1527-1315pii
radiol.10100163journal_volume
256pub_type
杂志文章相关文献
RADIOLOGY文献大全abstract::Anti-scatter grids reduce the amount of secondary radiation contributing to the image and improve the signal-to-noise ratio. However, they may also lead to the creation of linear artifacts representing the shadows of the radiopaque septa. Grid motion perpendicular to the septa during the exposure can cause blurring of...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.147.1.6828740
更新日期:1983-04-01 00:00:00
abstract:PURPOSE:To determine whether computed tomographic (CT) findings can help differentiate between benign and clinically worrisome causes of pneumatosis intestinalis (PI) in children. MATERIALS AND METHODS:This retrospective study was approved by the institutional review board, and requirement for informed consent was wai...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2532090168
更新日期:2009-11-01 00:00:00
abstract::The dynamics of white blood cell (WBC) and 67Ga-citrate accumulation were studied in rabbits with subcutaneous polyethylene chambers. Uninfected chamber fluid (CF) contained less than 1,000 WBCs/mm3, most of which were mononuclear. After 67Ga injection, radioactivity increased slowly in uninfected fluid, peaked betwee...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.140.1.6787660
更新日期:1981-07-01 00:00:00
abstract::In hepatic tumors seen in children, treatment and prognosis differ from tumor to tumor and thus accurate determination of their extent and characteristics is important. Evaluation by gray scale ultrasonography, radionuclide imaging and angiography has produced definable characteristics for the various tumor types and ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/124.2.451
更新日期:1977-08-01 00:00:00
abstract::High fecal impaction resulted in complete bowel obstruction in 2 children following renal transplantation and in one adult on chemotherapy and narcotics. The usual methods of relief failed, and water-soluble contrast enemas with a high osmolality were employed. Fluoroscopic control assured placement of the enema fluid...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/115.1.9
更新日期:1975-04-01 00:00:00
abstract::Purpose To investigate the prevalence of symptomatic carotid web in patients with acute ischemic stroke due to intracranial large vessel occlusion, to determine the clinical and imaging profile of patients with carotid web as well as their association with ischemic stroke, and to determine the interobserver agreement ...
journal_title:Radiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1148/radiol.2017170094
更新日期:2018-03-01 00:00:00
abstract::The efficacy and safety of two doses of recombinant human tissue-type plasminogen activator (rt-PA) were compared. Forty patients with peripheral arterial occlusions were treated with intraarterial rt-PA. Group A (n = 21) received 0.1 mg/kg/h, and group B (n = 19) received 0.05 mg/kg/h. Infusion durations varied from ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.164.2.3110860
更新日期:1987-08-01 00:00:00
abstract::Computed tomography (CT) used in cases of blunt abdominal trauma has been found sensitive in detection of bowel and mesenteric injuries and discrimination of operable from nonoperable candidates. In 51 patients with suspected bowel or mesenteric injury following blunt abdominal trauma, CT correctly depicted bowel hema...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.173.1.2781000
更新日期:1989-10-01 00:00:00
abstract::Transforaminal epidural steroid injections (TFESIs) are associated with rare but devastating neurologic complications. Every published case has been associated with a particulate steroid suspension, and the presumed but not proven mechanism is embolization and occlusion of end arterioles. Through an in vivo murine mod...
journal_title:Radiology
pub_type: 评论,杂志文章
doi:10.1148/radiol.2016160171
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:To compare the capability to aid prediction of clinical outcome measures, including progression-free survival (PFS) and overall survival (OS), between volumetric estimates from contrast material-enhanced (CE) T1-weighted subtraction maps and traditional segmentation in a randomized multicenter clinical trial of...
journal_title:Radiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1148/radiol.13131305
更新日期:2014-04-01 00:00:00
abstract::Distal splenorenal shunts were made in 25 patients with cirrhosis of the liver and portal hypertension. Angiograms were obtained in 16 patients at one week, three and six months, and at one year postoperatively. Portal vein flow had diminished in all patients compared with flow seen in preoperative angiograms. Hepatof...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/121.3.585
更新日期:1976-12-01 00:00:00
abstract::Purpose To determine the feasibility of creating a clinically relevant hepatic ablation (ie, an ablation zone capable of treating a 2-cm liver tumor) by using robotically assisted sonic therapy (RAST), a noninvasive and nonthermal focused ultrasound therapy based on histotripsy. Materials and Methods This study was ap...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2018171544
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:To retrospectively evaluate the prevalence of focal fluorodeoxyglucose (FDG) uptake by the thyroid gland on combined positron emission tomographic (PET) and computed tomographic (CT) scans in patients undergoing staging of newly diagnosed non-small cell lung cancer (NSCLC). MATERIALS AND METHODS:Institutional ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2361041007
更新日期:2005-07-01 00:00:00
abstract::A method of modified coronal computed tomography (CT) was developed for examination of epiphyseal growth plate arrest and neoplasms near the growth plate. Twenty-four patients were examined with this technique (26 examinations). In all cases, the growth plate and adjacent regions were well demonstrated. ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.166.1.3336690
更新日期:1988-01-01 00:00:00
abstract::The authors sought to render projection magnetic resonance (MR) angiograms depicting a substantial length of human coronary arteries from sequential breath-hold two-dimensional MR images. Tomographic images of the right and left anterior descending coronary arteries were collected with use of a segmented gradient-reca...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.187.3.8497620
更新日期:1993-06-01 00:00:00
abstract::Ultrasound-guided compression repair (UGCR) of catheterization-related femoral artery injuries was evaluated as a possible new imaging-guided interventional procedure. Thirty-nine femoral artery injuries (35 pseudoaneurysms, four arteriovenous fistulas) were detected with color Doppler flow imaging in patients with en...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.178.3.1994400
更新日期:1991-03-01 00:00:00
abstract::A retrospective analysis of 84 ultrasound examinations (in 77 patients) was performed to assess the frequency of sonographic findings in chronic pancreatitis. The findings included: inhomogeneously increased echogenicity in 53% of these examinations, focal or diffuse enlargement in 41%, focal dense echoes in 40%, pseu...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.155.1.3883420
更新日期:1985-04-01 00:00:00
abstract:PURPOSE:To assess relevant parameters for the minimally invasive elimination of breast tumors by using a selective application of magnetite and exposure of the breast to an alternating magnetic field. MATERIALS AND METHODS:The specific absorption rate (SAR) of different magnetite samples was determined calorimetricall...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.218.2.r01fe19570
更新日期:2001-02-01 00:00:00
abstract::To determine and quantify the major sources of anxiety for patients undergoing magnetic resonance (MR) imaging and to suggest means by which to eliminate or diminish their negative effects, the authors studied anxiety in 46 subjects. Of these, 20 randomly selected subjects who successfully completed the examination pa...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.170.2.2911670
更新日期:1989-02-01 00:00:00
abstract::Nine patients with biopsy-proved hepatocellular carcinoma underwent percutaneous ethanol ablation therapy (PEAT) with computed tomographic (CT) guidance. Twenty-five ablation sessions were performed in nine lesions ranging in size from 1.8 to 6.5 cm. Repeat biopsy was performed in seven of those nine lesions between 1...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.186.2.8380650
更新日期:1993-02-01 00:00:00
abstract::The authors prospectively treated 10 consecutive patients with multiloculated empyemas with intracavitary instillation of urokinase via a percutaneous drainage catheter. Urokinase (100,000 IU) in 100 mL of 5% dextrose in water was instilled into the pleural cavity via a percutaneous drainage catheter. After overnight ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.179.3.2027990
更新日期:1991-06-01 00:00:00
abstract::An aortobronchial fistula is a rare condition that is invariably fatal if not diagnosed and surgically treated. Aortic aneurysms, both atherosclerotic and infective, were the main causes in the originally described cases. However, thoracic cardiovascular surgery has recently become the predominant cause. The authors d...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.175.2.2326460
更新日期:1990-05-01 00:00:00
abstract:PURPOSE:To prospectively compare accuracy of dynamic contrast material-enhanced thin-section multi-detector row helical computed tomography (CT), high-spatial-resolution three-dimensional (3D) dynamic gadolinium-enhanced magnetic resonance (MR) imaging, and superparamagnetic iron oxide (SPIO)-enhanced MR imaging with o...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2371041444
更新日期:2005-10-01 00:00:00
abstract::Purpose To examine whether cardiac chemical exchange saturation transfer (CEST) imaging can be serially and noninvasively used to probe cell survival or rejection after intramyocardial implantation in mice. Materials and Methods Experiments were compliant with the National Institutes of Health Guidelines on the Use of...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2016152766
更新日期:2017-01-01 00:00:00
abstract::BackgroundMethylphenidate (MPH) is highly effective in treating attention-deficit/hyperactivity disorder (ADHD). However, not much is known about its effect on the development of human brain white matter (WM).PurposeTo determine whether MPH modulates WM microstructure in an age-dependent fashion in a randomized double...
journal_title:Radiology
pub_type: 杂志文章,随机对照试验
doi:10.1148/radiol.2019182528
更新日期:2019-10-01 00:00:00
abstract::Three cases of dilated abdominal left paraaortic lymphatic duct are described. The diagnosis was established by means of sonography and confirmed with lymphography in all three patients. A sonographically guided puncture of the lymphatic duct was performed in one patient. Dilatation of these lymphatic ducts was possib...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.167.3.3283840
更新日期:1988-06-01 00:00:00
abstract::A 7-year-old girl with histologically proved fibromuscular dysplasia underwent renal autotransplantation with prompt return of the blood pressure to normal. Two months later, immediately after tonsillectomy, severe hypertension recurred with marked narrowing of the previously patent anastomosis. After 4 weeks on antih...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/120.1.149
更新日期:1976-07-01 00:00:00
abstract::The effects of cyclosporin A (CyA), an immunosuppressive agent that is potentially nephrotoxic, on the kidneys of 9 liver transplant recipients were studied with serial 99mTc-DTPA and 131I-hippuran scans. In addition, renal function was determined by measuring serum creatinine levels during the second postoperative we...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.142.1.7031760
更新日期:1982-01-01 00:00:00
abstract:PURPOSE:To determine if prominent vascularity and low pulsatility index (PI) and resistive index (RI) in endometrial arteries help differentiate carcinoma from benign lesions. MATERIALS AND METHODS:Forty-five postmenopausal women with at least 8-mm-thick endometrium at endovaginal ultrasound (US) underwent color duple...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.195.3.7753990
更新日期:1995-06-01 00:00:00
abstract::The effect of transient renal ischemia on renal concentration and distribution of 99mTc-HEDP, 99mTc-DMSA, and 99mTc-DTPA was compared in rabbits with acute tubular necrosis. Scintigrams were obtained after injection in normal rabbits or ones with unilateral or bilateral ischemia. 99mTc-HEDP concentration in ischemic t...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/131.2.491
更新日期:1979-05-01 00:00:00