Abstract:
:The effect of transient renal ischemia on renal concentration and distribution of 99mTc-HEDP, 99mTc-DMSA, and 99mTc-DTPA was compared in rabbits with acute tubular necrosis. Scintigrams were obtained after injection in normal rabbits or ones with unilateral or bilateral ischemia. 99mTc-HEDP concentration in ischemic tissue was 8 to 18 times normal 1--4 hours after injection, and the resulting images delineated the morphological changes in the ischemic kidneys more accurately than those obtained with DMSA or DTPA. Calcium concentration in the ischemic kidneys increased sixfold. 99mTc-HEDP may be useful in evaluation of renal failure secondary to tubular injury.
journal_name
Radiologyjournal_title
Radiologyauthors
Lavelle KJ,Park HM,Moseman AM,Lewis Sdoi
10.1148/131.2.491subject
Has Abstractpub_date
1979-05-01 00:00:00pages
491-5issue
2eissn
0033-8419issn
1527-1315journal_volume
131pub_type
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