Intra-articular Corticosteroid Injections for the Treatment of Hip and Knee Osteoarthritis-related Pain: Considerations and Controversies with a Focus on Imaging-Radiology Scientific Expert Panel.

Abstract:

:Current management of osteoarthritis (OA) is primarily focused on symptom control. Intra-articular corticosteroid (IACS) injections are often used for pain management of hip and knee OA in patients who have not responded to oral or topical analgesics. Recent case series suggested that negative structural outcomes including accelerated OA progression, subchondral insufficiency fracture, complications of pre-existing osteonecrosis, and rapid joint destruction (including bone loss) may be observed in patients who received IACS injections. This expert panel report reviews the current understanding of pain in OA, summarizes current international guidelines regarding indications for IACS injection, and considers preinterventional safety measures, including imaging. Potential profiles of those who would likely benefit from IACS injection and a suggestion for an updated patient consent form are presented. As of today, there is no established recommendation or consensus regarding imaging, clinical, or laboratory markers before an IACS injection to screen for OA-related imaging abnormalities. Repeating radiographs before each subsequent IACS injection remains controversial. The true cause and natural history of these complications are unclear and require further study. To determine the cause and natural history, large prospective studies evaluating the risk of accelerated OA or joint destruction after IACS injections are needed. However, given the relatively rare incidence of these adverse outcomes, any clinical trial would be challenging in design and a large number of patients would need to be included.

journal_name

Radiology

journal_title

Radiology

authors

Guermazi A,Neogi T,Katz JN,Kwoh CK,Conaghan PG,Felson DT,Roemer FW

doi

10.1148/radiol.2020200771

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

503-512

issue

3

eissn

0033-8419

issn

1527-1315

journal_volume

297

pub_type

杂志文章,评审
  • Hepatocellular carcinoma: CT appearance after percutaneous ethanol ablation therapy. Work in progress.

    abstract::Nine patients with biopsy-proved hepatocellular carcinoma underwent percutaneous ethanol ablation therapy (PEAT) with computed tomographic (CT) guidance. Twenty-five ablation sessions were performed in nine lesions ranging in size from 1.8 to 6.5 cm. Repeat biopsy was performed in seven of those nine lesions between 1...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.186.2.8380650

    authors: Joseph FB,Baumgarten DA,Bernardino ME

    更新日期:1993-02-01 00:00:00

  • Hepatocellular carcinoma: hepatocyte-selective enhancement at gadoxetic acid-enhanced MR imaging--correlation with expression of sinusoidal and canalicular transporters and bile accumulation.

    abstract:PURPOSE:To investigate the mechanism of enhancement of hepatocellular carcinoma (HCC) on gadoxetic acid-enhanced hepatobiliary phase magnetic resonance (MR) images and to characterize HCC thus enhanced. MATERIALS AND METHODS:This retrospective study was approved by the institutional review board, and patient informed ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.10091557

    authors: Tsuboyama T,Onishi H,Kim T,Akita H,Hori M,Tatsumi M,Nakamoto A,Nagano H,Matsuura N,Wakasa K,Tomoda K

    更新日期:2010-06-01 00:00:00

  • Balloon dilation of ureteral strictures after renal transplantation.

    abstract::Ten ureteral strictures that developed in nine patients after renal transplantation were managed with balloon catheter dilation and placement of a ureteral stent. Four strictures were successfully dilated (40%), with a follow-up of 15-42 months (mean, 29 months). Comparison of these cases with the six cases of unsucce...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.186.3.8430180

    authors: Kim JC,Banner MP,Ramchandani P,Grossman RA,Pollack HM

    更新日期:1993-03-01 00:00:00

  • Comprehensive assessment of myocardial perfusion defects, regional wall motion, and left ventricular function by using 64-section multidetector CT.

    abstract:PURPOSE:To evaluate the accuracy of 64-section multidetector computed tomography (CT) for the assessment of perfusion defects (PDs), regional wall motion (RWM), and global left ventricular (LV) function. MATERIALS AND METHODS:All myocardial infarction (MI) patients signed informed consent. The IRB approved the study a...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2482071478

    authors: Cury RC,Nieman K,Shapiro MD,Butler J,Nomura CH,Ferencik M,Hoffmann U,Abbara S,Jassal DS,Yasuda T,Gold HK,Jang IK,Brady TJ

    更新日期:2008-08-01 00:00:00

  • Base-of-tongue cancer treated with external beam irradiation plus brachytherapy: oncologic and functional outcome.

    abstract::Between January 1981 and June 1990, 36 previously untreated patients with squamous cancer of the base of the tongue were treated with radiation therapy. This therapy consisted of a 5,000-5,400-cGy external beam plus a 2,000-3,000-cGy boost to the base of the tongue with an iridium-192 implant. Necks with negative node...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.184.1.1609090

    authors: Harrison LB,Zelefsky MJ,Sessions RB,Fass DE,Armstrong JG,Pfister DG,Strong EW

    更新日期:1992-07-01 00:00:00

  • Metabolic and destructive brain disorders in children: findings with localized proton MR spectroscopy.

    abstract::The diagnostic potential of volume-selective proton magnetic resonance (MR) spectroscopy in vivo was evaluated in 20 children and young adults with various neurodegenerative brain disorders. All patients were examined with MR spectroscopy in conjunction with MR imaging of the brain on a whole-body imager at 1.5 T. Com...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.181.1.1887030

    authors: Grodd W,Krägeloh-Mann I,Klose U,Sauter R

    更新日期:1991-10-01 00:00:00

  • Selective injection of contrast media: inflammatory effects on rabbit fallopian tubes.

    abstract::The inflammatory effects of fallopian tube catheterization and selective injection of seven contrast agents (ethiodized oil, diatrizoate meglumine 52%, diatrizoate meglumine 66%, iothalamate meglumine 60%, iopamidol, ioxitol, and ioxaglate) were evaluated in 88 rabbits. The contrast agent used was randomly selected an...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.180.1.1647040

    authors: Thurmond AS,Hedgpeth PL,Scanlan RM

    更新日期:1991-07-01 00:00:00

  • Antefemoral dissecting cysts in rheumatoid arthritis.

    abstract::Five cases of an antefemoral synovial cyst in rheumatoid arthritis were confirmed by arthrography. Communicating with the suprapatellar bursa, these rarely observed cysts may be considered an anterior analogy to dissecting Baker cysts. ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/133.2.343

    authors: Seidl G,Scherak O,Hofner W

    更新日期:1979-11-01 00:00:00

  • Testicular blood flow in boys as assessed at color Doppler and power Doppler sonography.

    abstract:PURPOSE:To investigate at which age testicular blood flow can be demonstrated consistently by color Doppler sonography and power Doppler sonography. MATERIALS AND METHODS:In this prospective study, 172 normal testes of 86 boys (age range, 4 days to 15 years) were examined with gray-scale ultrasound, color Doppler sono...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.202.2.9015090

    authors: Bader TR,Kammerhuber F,Herneth AM

    更新日期:1997-02-01 00:00:00

  • Focal liver masses: differential diagnosis with pulsed Doppler US.

    abstract::Duplex Doppler ultrasound (US) was used in 68 consecutive patients with focal liver lesions, including 12 hepatocellular carcinomas, one cholangiocarcinoma, 37 metastases, 15 hemangiomas, one hemangioendothelioma, and two focal nodular hyperplasias. Of the hepatocellular carcinomas, six were diffusely hyperechoic, two...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.164.3.3039570

    authors: Taylor KJ,Ramos I,Morse SS,Fortune KL,Hammers L,Taylor CR

    更新日期:1987-09-01 00:00:00

  • Mechanisms of severe, immediate reactions to iodinated contrast material.

    abstract:PURPOSE:To measure and elucidate the mechanisms of presumed mediators of unexpected severe, immediate reactions to iodinated contrast materials. MATERIALS AND METHODS:In a multicenter study, 20 patients with mild to severe reactions to iodinated contrast material and 20 control subjects without reactions were evaluate...

    journal_title:Radiology

    pub_type: 杂志文章,多中心研究

    doi:10.1148/radiology.209.1.9769830

    authors: Laroche D,Aimone-Gastin I,Dubois F,Huet H,Gérard P,Vergnaud MC,Mouton-Faivre C,Guéant JL,Laxenaire MC,Bricard H

    更新日期:1998-10-01 00:00:00

  • Iliac arterial occlusive disease: cost-effectiveness analysis of stent placement versus percutaneous transluminal angioplasty. Dutch Iliac Stent Trial Study Group.

    abstract:PURPOSE:To evaluate the relative benefits and cost-effectiveness of treating iliac arterial occlusive disease with various interventions. MATERIALS AND METHODS:Cost-effectiveness was analyzed in a hypothetical cohort of patients with intermittent claudication caused by an iliac arterial stenosis. Primary stent placeme...

    journal_title:Radiology

    pub_type: 杂志文章,meta分析

    doi:10.1148/radiology.208.3.9722840

    authors: Bosch JL,Tetteroo E,Mali WP,Hunink MG

    更新日期:1998-09-01 00:00:00

  • Enlarging fibroadenoma in a postmenopausal woman: case report.

    abstract::The authors describe mammographic and pathologic evidence of the growth of a fibroadenoma in an 82-year-old obese woman, 44 years after menopause, who had never been treated with hormone therapy. The patient's obesity is hypothesized as the causal factor for increased estrogen levels leading to growth of the fibroaden...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.184.2.1620840

    authors: Swisher RC,Gade NR,Suk JJ,Fu YS,Bassett LW

    更新日期:1992-08-01 00:00:00

  • Perforation of the inferior vena cava with aortic and vertebral penetration by a suprarenal Greenfield filter.

    abstract::Various complications have been reported after insertion of the Greenfield filter. This report describes an unusual complication after suprarenal placement of this filter: spreading of the filter struts, with perforation of the inferior vena cava, and penetration of the aorta and a vertebral body, followed by fracture...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.172.3.2772180

    authors: Kim D,Porter DH,Siegel JB,Simon M

    更新日期:1989-09-01 00:00:00

  • Rectosigmoid pseudostenosis due to urinary retention.

    abstract::Pseudostenosis of the rectosigmoid colon due to compression by a dilated urinary bladder may pose a diagnostic problem. Although probably quite common, it has not received much attention in the radiological literature. Four cases are presented and the radiological features on barium enema are described. ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/127.3.645

    authors: Kleinhaus U,Kaftori J

    更新日期:1978-06-01 00:00:00

  • Rheumatoid arthritis: evaluation of wrist extensor tendons with clinical examination versus MR imaging--a preliminary report.

    abstract::To determine whether magnetic resonance (MR) imaging can improve assessment of the extensor tendons of the wrist and their propensity to rupture, the dorsal tendons in 23 wrists in 20 patients with rheumatoid arthritis were clinically assessed and then examined with MR imaging. Clinical and MR imaging evaluations were...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.187.3.8497640

    authors: Rubens DJ,Blebea JS,Totterman SM,Hooper MM

    更新日期:1993-06-01 00:00:00

  • Vertebral-body collapse in focal and diffuse disease: patterns of pathologic processes.

    abstract::The radiographic patterns of vertebral-body collapse and/or endplate deformity were examined in 99 autopsy specimens of the thoracolumbar spine with benign and malignant disease. Angling of endplates was found to be highly predictive of underlying malignancy, whereas concavity was more suggestive of benign disease, fo...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.160.2.3726130

    authors: Sartoris DJ,Clopton P,Nemcek A,Dowd C,Resnick D

    更新日期:1986-08-01 00:00:00

  • Comparative Effectiveness of Thermal Ablation, Surgical Resection, and Active Surveillance for T1a Renal Cell Carcinoma: A Surveillance, Epidemiology, and End Results (SEER)-Medicare-linked Population Study.

    abstract::Purpose To compare adverse events and survival outcomes, including cancer-specific survival and overall survival (OS), in patients with T1aN0M0 renal cell carcinoma (RCC) who are undergoing partial nephrectomy (PN), radical nephrectomy (RN), thermal ablation (TA), or active surveillance (AS). Materials and Methods Thr...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2018171407

    authors: Xing M,Kokabi N,Zhang D,Ludwig JM,Kim HS

    更新日期:2018-07-01 00:00:00

  • Clinical Intravoxel Incoherent Motion and Diffusion MR Imaging: Past, Present, and Future.

    abstract::The concept of diffusion magnetic resonance (MR) imaging emerged in the mid-1980s, together with the first images of water diffusion in the human brain, as a way to probe tissue structure at a microscopic scale, although the images were acquired at a millimetric scale. Since then, diffusion MR imaging has become a pil...

    journal_title:Radiology

    pub_type: 杂志文章,评审

    doi:10.1148/radiol.2015150244

    authors: Iima M,Le Bihan D

    更新日期:2016-01-01 00:00:00

  • Ultrasonographic evaluation of juxtadiaphragmatic masses in children.

    abstract::The authors suggest that ultrasound be used in the evaluation of juxtadiaphragmatic lesions before resorting to other radiographic methods. This technique gives accurate diagnoses, serves as a guide for further studies, and might obviate more extensive procedures. ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/125.3.785

    authors: Kangarloo H,Sukov R,Sample WF,Lipson M,Smith L

    更新日期:1977-12-01 00:00:00

  • Reversible cystic disease associated with pulmonary tuberculosis: radiologic findings.

    abstract:PURPOSE:The authors describe radiologic findings of cystic lung disease associated with pulmonary tuberculosis. MATERIALS AND METHODS:Three immunocompetent women with pulmonary tuberculosis were seen with acute respiratory failure and diffuse bilateral pulmonary opacity depicted at admission chest radiography. The wom...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.204.1.9205240

    authors: Ko KS,Lee KS,Kim Y,Kim SJ,Kwon OJ,Kim JS

    更新日期:1997-07-01 00:00:00

  • The portacaval space: CT with MR correlation.

    abstract::Between the portal vein and the inferior vena cava lies a small space that may be occupied by multiple anatomic structures including the caudate and papillary processes of the caudate lobe of the liver, portacaval lymph nodes, replaced or accessory right hepatic arteries, posterosuperior pancreaticoduodenal vessels, t...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.156.2.4011910

    authors: Zirinsky K,Auh YH,Rubenstein WA,Kneeland JB,Whalen JP,Kazam E

    更新日期:1985-08-01 00:00:00

  • Percutaneous tumor ablation: increased coagulation by combining radio-frequency ablation and ethanol instillation in a rat breast tumor model.

    abstract:PURPOSE:To determine if percutaneously applied radio frequency (RF) combined with percutaneous ethanol instillation (PEI) can increase the extent of ablation in rat breast tumors. MATERIALS AND METHODS:R3230 mammary adenocarcinoma was implanted bilaterally in the mammary fat pads of 18 female rats. The tumor nodules m...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.217.3.r00dc27827

    authors: Goldberg SN,Kruskal JB,Oliver BS,Clouse ME,Gazelle GS

    更新日期:2000-12-01 00:00:00

  • Multisection CT protocols: sex- and age-specific conversion factors used to determine effective dose from dose-length product.

    abstract:PURPOSE:To determine conversion factors for the new International Commission on Radiological Protection (ICRP) publication 103 recommendations for adult and pediatric patients and to compare the effective doses derived from Monte Carlo calculations with those derived from dose-length product (DLP) for different body re...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.10100047

    authors: Deak PD,Smal Y,Kalender WA

    更新日期:2010-10-01 00:00:00

  • Transcatheter fiberoptic laser coagulation of blood vessels.

    abstract::In ten rabbit ears the central auricular artery was percutaneously catheterized and subjected to doses of laser energy transmitted through a flexible optical fiber within the artery. Arterial occlusion was not produced in the initial three ears using energy levels less than 600 mW. Higher levels of laser energy, in th...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.142.3.7199750

    authors: O'Reilly GV,Colucci VM,Astorian DG,Schoene WC,Clarke RH,Hammerschlag SB

    更新日期:1982-03-01 00:00:00

  • Lung cancer staging and management: comparison of contrast-enhanced and nonenhanced helical CT of the thorax.

    abstract:PURPOSE:To determine whether contrast material-enhanced helical computed tomography (CT) of the thorax and upper abdomen changes the tumor stage and management compared with nonenhanced helical CT in patients with newly diagnosed lung cancer. MATERIALS AND METHODS:During 15 months, any patient in whom lung cancer was ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.212.1.r99jl1956

    authors: Patz EF Jr,Erasmus JJ,McAdams HP,Connolly JE,Marom EM,Goodman PC,Leder RA,Keogan MT,Herndon JE

    更新日期:1999-07-01 00:00:00

  • Mapping the distribution of amobarbital sodium in the intracarotid Wada test by use of Tc-99m HMPAO with SPECT.

    abstract::The intracarotid amobarbital sodium, or Wada, test has been used to localize speech and memory function prior to surgical treatment of temporal lobe seizures. The authors mixed technetium-99m hexamethyl-propyleneamine oxime (HMPAO) with amobarbital sodium and injected the mixture in 25 patients with epilepsy. Single p...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.178.3.1994430

    authors: Jeffery PJ,Monsein LH,Szabo Z,Hart J,Fisher RS,Lesser RP,Debrun GM,Gordon B,Wagner HN Jr,Camargo EE

    更新日期:1991-03-01 00:00:00

  • Radiation risks of medical imaging: separating fact from fantasy.

    abstract::During the past few years, several articles have appeared in the scientific literature that predict thousands of cancers and cancer deaths per year in the U.S. population caused by medical imaging procedures that use ionizing radiation. These predictions are computed by multiplying small and highly speculative risk fa...

    journal_title:Radiology

    pub_type: 杂志文章,评审

    doi:10.1148/radiol.12112678

    authors: Hendee WR,O'Connor MK

    更新日期:2012-08-01 00:00:00

  • Intraosseous venous drainage anomaly in patients with pretibial varices: imaging findings.

    abstract:PURPOSE:To determine a set of distinctive imaging findings seen in symptomatic patients with pretibial varices. MATERIALS AND METHODS:Medical records and imaging studies of patients who presented with pretibial varices over an 8-year period were collected from four institutions. Findings in six symptomatic patients wi...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.202.3.9051030

    authors: Boutin RD,Sartoris DJ,Rose SC,Plecha EJ,Bundens WP,Haghighi P,Harter LP,Resnick D

    更新日期:1997-03-01 00:00:00

  • Adult respiratory distress syndrome from overdose of tricyclic antidepressants.

    abstract::Adult respiratory distress syndrome (ARDS) from overdose of tricyclic antidepressants (TCA) has been reported but is not well known. During a 1-year period, 81 patients with serious overdose from tranquilizers and other psychotropic drugs were examined. TCA alone induced overdose in 30 patients or were combined with o...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.170.3.2916020

    authors: Varnell RM,Godwin JD,Richardson ML,Vincent JM

    更新日期:1989-03-01 00:00:00