Base-of-tongue cancer treated with external beam irradiation plus brachytherapy: oncologic and functional outcome.

Abstract:

:Between January 1981 and June 1990, 36 previously untreated patients with squamous cancer of the base of the tongue were treated with radiation therapy. This therapy consisted of a 5,000-5,400-cGy external beam plus a 2,000-3,000-cGy boost to the base of the tongue with an iridium-192 implant. Necks with negative nodes were only irradiated, while necks with positive nodes were treated with irradiation plus neck dissection. Actuarial local control and survival at 2 years were 87.5%. Neck control was achieved in 35 of 36 patients. When implantation was performed with the nonlooping technique, the injury rate was statistically higher than in patients who underwent implantation with the looping technique (P = .02). Thirty patients participated in a function assessment involving a Performance Status Scale for patients with head and neck cancer. The authors concluded that management of base-of-tongue cancer with external beam irradiation plus brachytherapy is both oncologically and functionally successful.

journal_name

Radiology

journal_title

Radiology

authors

Harrison LB,Zelefsky MJ,Sessions RB,Fass DE,Armstrong JG,Pfister DG,Strong EW

doi

10.1148/radiology.184.1.1609090

subject

Has Abstract

pub_date

1992-07-01 00:00:00

pages

267-70

issue

1

eissn

0033-8419

issn

1527-1315

journal_volume

184

pub_type

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