Abstract:
PURPOSE:To determine if a correlation exists between the number of previous enhanced magnetic resonance (MR) imaging examinations and high signal intensity in the globus pallidus (GP) and dentate nucleus (DN) in patients who received gadodiamide (Omniscan), a linear nonionic gadolinium-based contrast agent, and in those who received gadobenate dimeglumine (MultiHance), a linear ionic contrast agent. MATERIALS AND METHODS:Institutional review board approval was obtained for this single-center retrospective study, with waiver of informed consent. The study population included 69 patients divided into two groups: Group 1 included patients who underwent gadodiamide-enhanced MR imaging, and group 2 included patients who underwent gadobenate dimeglumine-enhanced MR imaging. Two radiologists conducted a quantitative analysis of unenhanced T1-weighted images by using region of interest measurements. The GP-to-thalamus (TH) signal intensity ratio, DN-to-middle cerebellar peduncle (MCP) signal intensity ratio and relative percentage change (Rchange) between the first and last examinations for each patient were calculated. Relation between the signal intensity ratios and Rchange and the number of enhanced MR imaging examinations was analyzed by using a generalized additive model. Inter- and intraobserver agreement was evaluated with the Lin concordance correlation coefficient test. RESULTS:Group 1 included 23 patients (19 female), with a mean of 5.0 doses ± 2.4 (standard deviation) (range, 3-11 doses) administered. Group 2 included 46 patients (24 female) with a mean of 4.6 doses ± 2.2 (range, 3-11 doses) administered. The interval between the first and last examination was 1500.1 days ± 780.2 (range, 98-3097 days) for group 1 and 1086.2 days ± 582.9 (range, 94-2633) for group 2. All patients had normal liver and renal function. Gadodiamide showed a significant increase in DN:MCP and GP:TH (P < .001 for both) and in Rchange (P = .001 for GP:TH, P < .001 for DN:MCP). In group 2, there was no significant increase in DN:MCP or GP:TH over time or in Rchange for GP:TH, but there was a significant trend toward an increase in Rchange for DN:MCP (P = .013). Interobserver agreement was almost perfect (0.99; 95% confidence interval: 0.99, 0.99) for all evaluated structures. Intraobserver agreement was substantial to almost perfect for both readers. CONCLUSION:A significant increase in GP:TH and DN:MCP is associated with multiple gadodiamide-enhanced studies but not with gadobenate dimeglumine-enhanced studies, likely reflecting differences in stability and elimination of both contrast agents. Rate-of-change data indirectly suggest gadolinium deposition in the DN with gadobenate dimeglumine use, although it is considerably less than that with gadodiamide use.
journal_name
Radiologyjournal_title
Radiologyauthors
Ramalho J,Castillo M,AlObaidy M,Nunes RH,Ramalho M,Dale BM,Semelka RCdoi
10.1148/radiol.2015150872subject
Has Abstractpub_date
2015-09-01 00:00:00pages
836-44issue
3eissn
0033-8419issn
1527-1315journal_volume
276pub_type
杂志文章相关文献
RADIOLOGY文献大全abstract::Magnetic resonance (MR) imaging of the hip has been useful in the examination of patients for the presence of avascular necrosis (AVN). In the detection of AVN, MR imaging is more sensitive than computed tomography or nuclear scintigraphy. This study assessed the usefulness of MR imaging in the differentiation of AVN ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.169.1.3420260
更新日期:1988-10-01 00:00:00
abstract:PURPOSE:To review the incidence, cause, and radiologic findings of bowel obstruction in patients who have undergone orthotopic liver transplantation (OLT). MATERIALS AND METHODS:Retrospective review of 4,001 cases of OLT revealed 48 cases of bowel obstruction in 44 patients. Seventeen computed tomographic (CT) scans a...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.218.2.r01ja22384
更新日期:2001-02-01 00:00:00
abstract::We attempted to use hand-held, high-resolution breast sonography to localize for biopsy 11 solid, nonpalpable lesions detected by mammography. Using sonography, we identified and localized only one of four lesions presenting as poorly defined masses and only one of seven lesions presenting as clusters of tiny calcific...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.155.3.3890010
更新日期:1985-06-01 00:00:00
abstract:PURPOSE:To determine the individual technical costs of general diagnostic radiographic, ultrasonographic (US), computed tomographic (CT), magnetic resonance (MR) imaging, and scintigraphic examinations and interventional radiology. MATERIALS AND METHODS:The Radiology Cost and Productivity Benchmarking Study method of ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.216.1.r00jl18269
更新日期:2000-07-01 00:00:00
abstract::A case of tuberculosis mimicking carcinoma in the distal colon is reported. The difficulty in diagnosing a solitary tuberculous colonic lesion, a review of the literature, and a differential diagnosis are presented. ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/118.2.293
更新日期:1976-02-01 00:00:00
abstract:PURPOSE:To describe a benign nodular lesion in the peripheral zone (PZ) of the prostate gland. MATERIALS AND METHODS:In 1,087 patients, the features of 722 focal lesions in the PZ or central zone of the prostate on transrectal ultrasound (TRUS) scans were retrospectively compared with histologic findings in biopsy sam...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.189.3.7694310
更新日期:1993-12-01 00:00:00
abstract::Background Normalized iodine concentration (NIC) (ratio of iodine concentration of liver to that of aorta) of liver at delayed dual-energy CT (DECT) may reflect the amount of fibrosis based on the extent of iodine uptake. Purpose To stage liver fibrosis by using 5-minute delayed DECT and compare findings with those of...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2021202232
更新日期:2021-01-05 00:00:00
abstract::A fluid collection within the retropubic space has a characteristic sonographic contour which, when combined with a partially distended bladder, resembles a yoke over a bell. The fluid conforms to the anterior convexity of the bladder. This configuration is distinct from that of ascites or a lymphadenectomy-related ly...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.147.1.6828730
更新日期:1983-04-01 00:00:00
abstract::The effectiveness of three methods of assessing the patient body burden following 131I therapy was compared: (a) urine assay, (b) external exposure rate measurements, and (c) predictions based on a pretherapy diagnostic work-up. The urine assay method exhibited the greatest potential for error and personnel risk. The ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.137.3.7444070
更新日期:1980-12-01 00:00:00
abstract::Inferior vena cava filters were placed in 60 patients. Ultrasound (US) of the venous access site was performed before and 3-5 days after filter placement to determine the prevalence of occlusive and nonocclusive access-site thrombosis (AST). Prevalence of symptoms attributable to AST was also evaluated at 1-month clin...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.185.1.1523320
更新日期:1992-10-01 00:00:00
abstract:PURPOSE:To test, by using an electrotransfer protocol for the transfection of skeletal muscle with naked plasmid complementary DNA, whether in vivo magnetic resonance (MR) imaging can help delineate either the spatial extent of the electric field when contrast agent is injected intraperitoneally or the transfection are...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2283020482
更新日期:2003-09-01 00:00:00
abstract::Purpose To determine the effect of radiation dose and iterative reconstruction (IR) on noise, contrast, resolution, and observer-based detectability of subtle hypoattenuating liver lesions and to estimate the dose reduction potential of the IR algorithm in question. Materials and Methods This prospective, single-cente...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2017161736
更新日期:2017-09-01 00:00:00
abstract:PURPOSE:To investigate in vivo the feasibility of using magnetic resonance (MR) imaging-derived temperature and thermal dose measurements to find the threshold of thermal tissue damage. MATERIALS AND METHODS:Sonications were delivered in rabbit thigh muscles at varying powers. Temperature-sensitive MR images obtained ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.216.2.r00au42517
更新日期:2000-08-01 00:00:00
abstract:PURPOSE:To investigate the mechanism of enhancement of hepatocellular carcinoma (HCC) on gadoxetic acid-enhanced hepatobiliary phase magnetic resonance (MR) images and to characterize HCC thus enhanced. MATERIALS AND METHODS:This retrospective study was approved by the institutional review board, and patient informed ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.10091557
更新日期:2010-06-01 00:00:00
abstract::Eighty-nine patients were evaluated for coronary artery disease (CAD) with exercise radionuclide ventriculography (ERV) and contrast coronary angiography. In 70 patients with documented lesions the ERV was abnormal in 65 for a sensitivity of 93%. In patients with normal coronary arteries, the ERV was abnormal in none ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/132.3.697
更新日期:1979-09-01 00:00:00
abstract::An analog model of the part of a patient's body containing a tumor is constructed by drawing anatomical contours obtained from computed tomograms on a set of transparent plastic sheets. The coverage of radiotherapy fields in the patient is visualized in three dimensions using the model and the light beam from the radi...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.136.1.7384510
更新日期:1980-07-01 00:00:00
abstract::Digital subtraction angiography (DSA) using a 41-cm (16-in.) image intensifier was performed in 144 patients with peripheral vascular insufficiency. In most cases the entire peripheral vascular bed from the renal arteries to the popliteal trifurcation was demonstrated with four intravenous injections and four exposed ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.149.3.6359260
更新日期:1983-12-01 00:00:00
abstract:PURPOSE:To provide a broad perspective concerning the recent use of receiver operating characteristic (ROC) analysis in medical imaging by reviewing ROC studies published in Radiology between 1997 and 2006 for experimental design, imaging modality, medical condition, and ROC paradigm. MATERIALS AND METHODS:Two hundred...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2533081632
更新日期:2009-12-01 00:00:00
abstract::Background Comprehensive assessments of the frequency and associated doses from radiologic and nuclear medicine procedures are rarely conducted. The use of these procedures and the population-based radiation dose increased remarkably from 1980 to 2006. Purpose To determine the change in per capita radiation exposure i...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2020192256
更新日期:2020-05-01 00:00:00
abstract::Osteoid osteoma is a benign, self-limited tumor of bone that usually requires surgical excision for relief of pain and to prevent long-term consequences. Radio-frequency electrodes have been successfully and safely used to ablate small areas of the central nervous system and to perform ablation elsewhere in the body. ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.183.1.1549690
更新日期:1992-04-01 00:00:00
abstract:PURPOSE:To assess retrospectively the incidence, clinical features, and treatment of colonic perforation at computed tomographic (CT) colonography in a large multicenter cohort. MATERIALS AND METHODS:The study was performed in accordance with the institutional ethics committees' requirements of a retrospective review ...
journal_title:Radiology
pub_type: 杂志文章,多中心研究
doi:10.1148/radiol.2392050287
更新日期:2006-05-01 00:00:00
abstract::Spermatic venography with hot contrast material embolization was undertaken in 81 patients with varicoceles and infertility. Long-term follow-up information was available in 91% of the patients, and there was an overall conception rate of 40.5%. Embolization with hot contrast material was easily performed without spec...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.168.1.3380950
更新日期:1988-07-01 00:00:00
abstract::A simple device is described that can reduce personnel exposure from scatter radiation by up to 75%. The device consists of an oblong piece of shielding (0.75-mm lead equivalent) that is taped to the side of the patient during percutaneous renal stone removal and other interventional procedures. Contrary to other shie...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.159.3.3704160
更新日期:1986-06-01 00:00:00
abstract:PURPOSE:To retrospectively determine and compare the sensitivity and specificity of unenhanced and contrast material-enhanced computed tomography (CT) (reference standard) in the diagnosis of brain abnormalities and to evaluate any change in diagnosis that resulted from the contrast-enhanced study. MATERIALS AND METHO...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2443051785
更新日期:2007-09-01 00:00:00
abstract::Three groups of apparently normal developmental variants in extremities as they appear on radiographs are presented. In contrast to the widely held view that these are of no clinical significance, these ossicles may, in fact, be responsible for symptoms. The first group consists of ossicles which, from the very onset,...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.157.3.4059550
更新日期:1985-12-01 00:00:00
abstract::Digital radiographs obtained with a CT scanner were evaluated as an alternative to conventional pelvimetry. Dosimetry studies demonstrated an absorbed radiation dose of 22 mrad for each digital radiograph, approximately 3% of the dose for comparable standard radiographs. Distance measurements were accurately made on d...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.143.3.7079500
更新日期:1982-06-01 00:00:00
abstract:PURPOSE:To compare the diagnostic accuracy of two-dimensional (2D) full-field digital mammography with that of two-view (mediolateral and craniocaudal) and single-view (mediolateral oblique) tomosynthesis in an observer study involving two institutions. MATERIALS AND METHODS:Ethical committee approval was obtained. Al...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.11103514
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To evaluate the value of magnetic resonance (MR) imaging with a flexible surface coil in predicting the resectability of tumors in the lower rectum and the feasibility of sphincteral salvage. MATERIALS AND METHODS:In a prospective study, 61 patients with histologically proved primary adenocarcinoma of the lowe...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.214.2.r00fe08503
更新日期:2000-02-01 00:00:00
abstract::This study evaluates the mammographic findings in 352 patients, aged 30-85 years, who underwent spot localization and biopsy for evaluation of nonpalpable breast abnormalities. Malignancy was found at biopsy in 114 cases. The mammographic appearance (specifically, whether grouped microcalcifications, mass, or both wer...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.169.2.2845470
更新日期:1988-11-01 00:00:00
abstract::Purpose To evaluate the safety and efficacy of palliative treatment of patients with pathologic pelvic by using fluoroscopy and cone-beam CT needle guidance software to perform percutaneous fixation by internal cemented screw (FICS). Materials and Methods This single-center study involved retrospective analysis of 100...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2018181105
更新日期:2019-02-01 00:00:00