Autoimmune reactions in patients with silicone breast implants.

Abstract:

:Silicone breast implants have been surgical routine for over 30 years. An association between silicone augmentation and immune related diseases has been reported in approximately 100 cases. In a retrospective single center study we investigated 36 non-selected women with silicone breast implants and 36 sex- and age-matched controls. Autoimmune reactions were evaluated by measuring antinuclear antibodies (ANA), rheumatoid factor (RF) and thyroid gland antibodies (TMS), along with angiotensin-converting enzyme (ACE), C-reactive protein (CRP) and other immunological and laboratory parameters. In the controls only 3 (8%) women had an elevated ANA titer and 1 demonstrated thyroid autoantibodies (microsomal), giving a total of 4 (11%) women with detectable autoantibodies. By contrast, 12 (33%) of the 36 women with silicone augmentation had raised ANA titers (> or = 1 : 80), a significantly higher percentage than in the control group (p < 0.02). Of the 12 women, 1 showed antismooth muscle antibodies (ASMA; titer 1 : 40) and 2 of the patients displayed antineutrophilic cytoplasm antibodies (ANCA; 1 : 320 and 1 : 40, respectively), one of the latter also being positive for rheumatoid factor. 2 further women demonstrated thyroid autoantibodies (microsomal), giving a total of 14 (39%) women in whom significant autoantibodies were detectable. Clinical symptoms (musculoskeletal) were present in 1 patient. Most of the observed autoantibodies were organ-unspecific, with a predominance of elevated ANA titers of the heterogeneous type and not related to a distinct clinical entity. However, none of the investigated women with silicone breast implants showed clinical symptoms or signs of connective tissue disease according to ARA criteria.

journal_name

Wien Klin Wochenschr

authors

Zazgornik J,Piza H,Kaiser W,Bettelheim P,Steiner G,Smolen J,Biesenbach G,Maschek W

subject

Has Abstract

pub_date

1996-12-27 00:00:00

pages

781-7

issue

24

eissn

0043-5325

issn

1613-7671

journal_volume

108

pub_type

杂志文章
  • [Inhibition of opsonization of E. coli by enzyme-treated gammaglobulin (author's transl)].

    abstract::The influence of Cohn fraction II, pepsin- and plasmin-treated gammaglobulin on the opsonization of E. coli 0111 was investigated. Normal serum at different dilutions, as well as serum of patients with different forms of antibody deficiency syndromes were tested. No effect was observed by pre-incubation of the bacteri...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Eibl M,Friers G

    更新日期:1978-10-27 00:00:00

  • [10 years foodborne listeriosis--an evaluation].

    abstract::Foodborne listeriosis outbreaks, which occurred in the past 10 years, have raised new questions in listeriosis epidemiology. The renewed interest in listeriosis and Listeria monocytogenes has resulted in various efforts, which enormously enriched the knowledge about his relatively rare, but because of the high mortali...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,评审

    doi:

    authors: Brosch R,Buchrieser C,Sixl W,Rocourt J

    更新日期:1992-01-01 00:00:00

  • [A patient with idiopathic bronchiolitis obliterans with organizing pneumonia and idiopathic CD4+ T-lymphocytopenia].

    abstract::Idiopathic bronchiolitis obliterans organizing pneumonia (idiopathic BOOP) and idiopathic CD4+ T lymphocytopenia are syndromes of unknown origins which have been characterized in recent years. An important feature of both syndromes is the good prognosis. The clinical and histological features of idiopathic BOOP are un...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Pohl W

    更新日期:1996-01-01 00:00:00

  • [Risk of occupational hepatitis B in gynecologic and obstetric units in Austria].

    abstract::Evaluation of the hepatitis-B data of the Austrian Workers' Compensation Board (AWCB), where the results of the serological findings of the markers HBsAg, anti-HBs and anti-HBc are stored, allows the following conclusions to be reached regarding persons employed in gynaecological departments: The average hepatitis-B i...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Maruna H,Winker N

    更新日期:1987-04-17 00:00:00

  • Genospecies and their influence on immunoblot results.

    abstract::In Europe at least three human pathogenic species of Borrelia burgdorferi sensu lato are the causative agents of Lyme borreliosis. All three species have been isolated or detected by PCR from skin, CSF and synovial fluid of patients with skin lesions, neuroborreliosis and Lyme arthritis respectively. Studies using str...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,评审

    doi:

    authors: Wilske B,Hauser U,Lehnert G,Jauris-Heipke S

    更新日期:1998-12-23 00:00:00

  • Elecsys TSH, FT4, T4, T-uptake, FT3 and T3. Clinical results of a multicentre study.

    abstract::6 assays for the assessment of thyroid function (TSH, FT4, T4, T-uptake, FT3 and T3) were targets of the International Multicenter Study on the random access analyzer Elecsys 2010. The aim of the study was to characterize the clinical performance of the assay in method comparison and reference range studies. The assay...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Ebert C,Bieglmayer C,Igari J,Chan D,Torralba A,Müller C,Veys A,Bätz O,Dageförde S,Roth HJ,Neumeier D,Assmann G,Banfi GM,Yvert JP

    更新日期:1998-01-01 00:00:00

  • Austrian Arbeitsgemeinschaft für Gynäkologische Onkologie (AGO) guideline for prophylaxis with granulocyte colony-stimulating factors (G-CSF) in gynecologic malignancies, including breast cancer.

    abstract::The current knowledge and recommendations on the clinical use of granulocyte colony-stimulating factors (G-CSF) in gynecologic cancers including breast cancer, along with the clinical experience of the members of the working group of the Austrian Arbeitsgemeinschaft für Gynäkologische Onkologie (AGO), have been summar...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,实务指引

    doi:10.1007/s00508-012-0185-2

    authors: Petru E,Zeimet AG,Sevelda P,Seifert M,Singer C,Hubalek M,Angleitner-Boubenizek L,Speiser P,Benedicic C,Stummvoll W,Reinthaller A,Austrian Arbeitsgemeinschaft für Gynäkologische Onkologie (AGO).

    更新日期:2012-06-01 00:00:00

  • Factors associated with motor performance among overweight and nonoverweight Tyrolean primary school children.

    abstract:BACKGROUND:The increasing prevalence of overweight and obesity among children is often associated with motor deficits. Motor performance among children partly depends on modifiable factors, for example, weight status, electronic media use, sports club participation, and on nonmodifiable factors, for example, sex, age, ...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-015-0887-3

    authors: Ruedl G,Greier K,Kirschner W,Kopp M

    更新日期:2016-01-01 00:00:00

  • [Cryptosporidia associated gastroenteritis: epidemiologic study of children in Tyrol and Vorarlberg].

    abstract::Stool samples from 523 children aged between 3 months and 6 years were examined for Cryptosporidium parvum by means of the direct immunofluorescence technique in March 1996. The specimens were sent to the Federal Public Health Laboratory in Innsbruck from general practitioners and pediatricians and from hospitals in T...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Lederer W,Allerberger F,Dierich MP

    更新日期:1996-01-01 00:00:00

  • Body mass index and height in 11- to 16-year-old Austrian students attending two different school types with divergent socioeconomic backgrounds.

    abstract:BACKGROUND:In developed countries high socioeconomic status (SES) is associated with lower body mass index (BMI) and greater height compared with low SES. AIM:To investigate differences in BMI/height in adolescent students from two different school types with divergent SES backgrounds. METHODS:A total of 4579 student...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-019-1479-4

    authors: Riedl S,Riedl-Schlauss V,Häusler G,Gleiss A

    更新日期:2019-07-01 00:00:00

  • [Ambroxol versus betamethasone for the promotion of antepartum lung maturity in pathological pregnancies].

    abstract::Although glucocorticoids have been universally implemented to stimulate fetal lung maturity, their effectiveness and side effects are still widely contested. In search of alternative drugs a double-blind study was conducted between June 1981 and June 1984 comparing betamethasone, a conventional corticoid, and ambroxol...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Heytmanek G,Salzer H,Vityska-Binstorfer E,Genger H,Metka M,Pfersmann R,Wolff F,Weidinger H

    更新日期:1990-08-03 00:00:00

  • [Chlamydia antibody titers in patients with coronary disease: relations to age and clinical stage].

    abstract:BACKGROUND AND AIM:Atherosclerosis and its clinical sequelae are responsible for the highest death rate in industrialized countries. Seroepidemiological, pathological and immunohistochemical studies have suggested a relation between Chlamydia pneumoniae infection and the development of coronary sclerosis. Aim of this s...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: el-Rabadi K,Gottsauner-Wolf M,Christ G,Maurer G,Huber K

    更新日期:2001-10-15 00:00:00

  • [Radiotherapeutic methods in the management of ovarian cancer (author's transl)].

    abstract::A report is given of the therapeutic strategy and the stage-adjusted methods of irradiation in the treatment of ovarian cancer. The influence of radical surgery, irradiation and chemotherapy on survival rates is discussed and the results achieved in this unit, especially in patients admitted at a more advanced tumour ...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Kärcher KH

    更新日期:1980-04-25 00:00:00

  • [Leopold Schönbauer and the Vienna Society of Physicians].

    abstract::Schönbauer's merits for the Society of Physicians in Vienna not only concern the renovation of its building after the Second World War but also his active scientific co-operation during four decades. His lectures are primarily devoted to abdominal surgery and neuro-surgery. ...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Wyklicky H

    更新日期:1988-12-02 00:00:00

  • Filgrastim-alone versus pegylated filgrastim-alone for autologous peripheral blood stem cells mobilization in newly diagnosed multiple myeloma patients.

    abstract:BACKGROUND:Autologous hematopoietic stem cell transplantation (aHSCT) is the recommended standard upfront treatment for transplant eligible myeloma patients. Considering possible complications related to chemotherapy-cytokine mobilization, cytokine-alone mobilization is often used. We compared mobilization with filgras...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00508-017-1205-z

    authors: Skopec B,Skerget M,Zontar D,Zadnik V,Zver S

    更新日期:2017-08-01 00:00:00

  • [Gestational diabetes mellitus (Update 2019)].

    abstract::Gestational diabetes mellitus (GDM) is defined as a glucose tolerance disorder with onset during pregnancy and is associated with increased feto-maternal morbidity as well as long-term complications in mother and child. Women who fulfil the criteria of a manifest diabetes in early pregnancy (fasting plasma glucose >12...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,评审

    doi:10.1007/s00508-018-1419-8

    authors: Kautzky-Willer A,Harreiter J,Winhofer-Stöckl Y,Bancher-Todesca D,Berger A,Repa A,Lechleitner M,Weitgasser R

    更新日期:2019-05-01 00:00:00

  • [Aneurysma spurium after iatrogenic arterial puncture--incidence, risk factors and surgical therapy].

    abstract::Due to the markedly increased number of arterial punctures performed during diagnostic angiography and angioplasty procedures for cardiac and peripheral vessel disease, the complication of false aneurysms after arterial puncture has gained increasing significance. The incidence of false aneurysms after puncture report...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Trubel W,Staudacher M,Magometschnigg H,Wolner E

    更新日期:1993-01-01 00:00:00

  • [Possibilities and limits of cytostatic chemotherapy in pancreatic carcinoma].

    abstract::The investigation of chemotherapy for pancreatic cancer has been hampered by the fact that most patients present with severe general illness and thus tolerate this form of treatment poorly. Furthermore, because of the relative inaccessibility of the pancreas it has been difficult to monitor objective response rates. I...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,评审

    doi:

    authors: Scheithauer W

    更新日期:1994-01-01 00:00:00

  • [Pharmacology of DTIC (author's transl)].

    abstract::DTIC, a new cytostatic drug developed by the NCI-USA, is described and some relevant pharmacological characteristics are defined. This drug was proved to be the number one choice for the treatment of malignant melanoma and of sarcomas. It also appears to be of value in advanced cases of Hodgkins disease. DTIC represen...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章,评审

    doi:

    authors: Karrer K

    更新日期:1978-12-22 00:00:00

  • [The accuracy of transrectal aspiration biopsy in routine diagnosis of prostatic carcinoma].

    abstract::Over a period of four years 352 patients suspected of having a carcinoma of the prostate were investigated and 463 cytological and 343 histological examinations were undertaken. In 340 cases the cytological findings on transrectal aspiration biopsy according to Franzen [14] were compared with the histological findings...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Maier U,Holub G,Krepler R

    更新日期:1980-11-21 00:00:00

  • [Herpes zoster oticus -- neuropathologic contribution to the genesis of concomitant facial paralysis (author's transl)].

    abstract::A woman of 71 years suffered from herpes zoster oticus, 7th and 10th nerve paralysis, vertigo and hearing loss; she died after 5 weeks. Neuropathologic examination revealed intensive inflammation in the pons and medulla oblongata and necrotizing arteritis in the cerebello-pontine angle, predominantly on the clinically...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Pilz P

    更新日期:1981-12-25 00:00:00

  • [Alcohol-induced type V hyperlipidemia in relation to changes in the chemical composition of HDL2].

    abstract::Alcohol consumption is one of the most common causes of secondary hyperlipidaemia in man, but not all alcohol addicts display hyperlipidaemia. 10 healthy male controls were compared with three groups of patients. The first group consisted of 9 heavy drinkers exhibiting type V hyperlipidaemia under the influence of alc...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Breier C,Lisch HJ,Braunsteiner H

    更新日期:1985-03-29 00:00:00

  • Competency and educational needs in palliative care.

    abstract:PURPOSE:To explore general practitioners' (GPs') and nurses' self assessment of professional education, competency and educational needs in palliative care. METHODS:All 897 registered GPs and all 933 registered home care nurses in the Province of Styria/Austria were sent postal questionnaires to evaluate their profess...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-006-0724-9

    authors: Becker G,Momm F,Gigl A,Wagner B,Baumgartner J

    更新日期:2007-01-01 00:00:00

  • [Chronic thromboembolic pulmonary hypertension and its treatment with pulmonary thrombendarterectomy].

    abstract::Chronic recurrent pulmonary embolism can lead to extensive pulmonary hypertension by obstruction of the pulmonary vessels. Pulmonary thrombendarteriectomy is a new approach to normalizing the elevated pulmonary vascular resistance by removal of the adsorbed thrombi. Between 1992 and 1994 we have operated on 8 patients...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Klepetko W,Moritz A,Burghuber OC,Ziesche R,Kneussl M,Lang I,Mares P,Hiesmayer M,Kontrus M,Herold C

    更新日期:1995-01-01 00:00:00

  • [Serum hydroxyproline parameter of collagen metabolism (author's transl)].

    abstract::The serum hydroxyproline level enables a clinical assessment to be made of bone metabolism. A clinical-chemical method, which is described in detail, was applied in 50 control persons as well as in 76 patients with diseases of bones and/or joints. This method, which is a modification of the standard ion-exchange metho...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Raab W,Pemp W,Schwägerl W

    更新日期:1981-03-06 00:00:00

  • [The "Asthma Programme" (author's transl)].

    abstract::The "asthma programme", the product of teamwork between the 1st Department of Dermatology and the 2nd Department of Medicine is presented. It contains all examinations necessary for the diagnosis of bronchial asthma: case history, skin test, IgE, RAST, lung function test, inhalative provocation test. The value of each...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Jarisch R,Kummer F,Oppolzer R

    更新日期:1975-11-28 00:00:00

  • [Satellite associations in trisomy 21 (author's transl)].

    abstract::Satellite associations and cell-cycle kinetics were investigated in short-term blood cultures from selected pairs of chromosomally normal persons and patients with trisomy 21. The cell-cycle duration was found to be longer in patients with trisomy than in normal persons. The frequency of satellite associations and the...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Wachtler F,Andrle M,Rett A

    更新日期:1981-01-09 00:00:00

  • Lab-score is a valuable predictor of serious bacterial infection in infants admitted to hospital.

    abstract::Parents frequently bring their children to the Emergency Department (ED) because of the fever without apparent source (FWAS). To avoid possible complications, it is important to recognize serious bacterial infection (SBI) as early as possible. Various tests, including different clinical scores and scales, are used in ...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:10.1007/s00508-015-0831-6

    authors: Markic J,Kovacevic T,Krzelj V,Bosnjak N,Sapunar A

    更新日期:2015-12-01 00:00:00

  • [Problems of diagnostic typology of married couples in therapy].

    abstract::Over the past years there has been great interest in developing diagnostic typologies of married couples undergoing therapy. 92 couples admitted to therapy were asked to fill out the Giessen test, a test widely used for diagnosis in marital therapy. The method of cluster analysis was used to find a classification. The...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Reiter L

    更新日期:1983-07-08 00:00:00

  • [Accelerated degradation of prostacyclin in diabetic plasma--a further factor in the impairment of hemostatic balance?].

    abstract::Prostacyclin is degraded in human plasma in vitro with an average half-life of 10 minutes. The degradation in plasma of patients suffering from type II diabetes mellitus is significantly enhanced. However, the inactivation of prostacyclin in plasma in patients with clinical manifestations of atherosclerosis, such as p...

    journal_title:Wiener klinische Wochenschrift

    pub_type: 杂志文章

    doi:

    authors: Sinzinger H,Kaliman J,Fitscha P,Peskar BA

    更新日期:1985-09-13 00:00:00