Abstract：
:A Health Hazard Evaluation was conducted by the National Institute for Occupational Safety and Health in an area of a large chemical plant that manufactured the stilbene derivative 4,4'-diaminostilbene-2,2'-disulfonic acid, an intermediate used for the production of optical brightening agents. Men employed in the area reported problems with impotence. The study population consisted of 44 men aged 20-57 years (mean age 37) employed in the area at the time of the evaluation. An industrial hygiene investigation, health and work history questionnaire survey, physical examinations, and blood chemistry and serum hormone evaluation were conducted. Fourteen percent of the men reported symptoms of impotence over the preceding 6 or more months, 7% had potency problems of shorter duration, and 7% were not currently impotent but had experienced impotence for 6 or more months in the past; 36% experienced decreased libido, all since beginning work in the production area. Low levels of serum testosterone (less than 350 ng/dl) were observed in 37% of the men. The low serum testosterone concentrations were not accounted for fully by diurnal variation or an effect of rotating shift work. It is suggested that exposures to chemicals possessing estrogenic activity may be related to the observed health effects in these workers.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Quinn MM,Wegman DH,Greaves IA,Hammond SK,Ellenbecker MJ,Spark RF,Smith ERdoi
10.1002/ajim.4700180107subject
Has Abstractpub_date
1990-01-01 00:00:00pages
55-68issue
1eissn
0271-3586issn
1097-0274journal_volume
18pub_type
杂志文章abstract：BACKGROUND:Exposure to dichloromethane (DCM or methylene chloride - CH₂ Cl₂ ) in paint strippers continues to be an avoidable source of morbidity and mortality. DCM has been under regulatory scrutiny by occupational and consumer product agencies since the identification of its carcinogenicity in the mid-1980s. METHODS...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22167
更新日期：2013-08-01 00:00:00
abstract：:A cross-sectional prevalence study of 120 public school custodians was carried out. The purposes were 1) to investigate the prevalence of asbestos-related disease in a group of custodians at risk for asbestos exposure in public schools and 2) to determine the proportion with disease attributable to exposures in school...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700190305
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:The mortality experience of iron and steel workers from modern plants in developing countries has not been extensively described. METHODS:Mortality at two Korean iron and steel manufacturing complexes was analyzed using Poisson regression methods with both direct and indirect standardization. Work histories...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20197
更新日期：2005-09-01 00:00:00
abstract：:In conjunction with industrial hygiene surveys, mutagenicity studies were performed for the airborne contaminants in three polyurethane manufacturing plants. Airborne particles were collected on glass-fiber filters with Hi-Vol pumps from different locations in each plant. Gases were collected in multiple-sorbent cartr...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700110410
更新日期：1987-01-01 00:00:00
abstract：BACKGROUND:Mineral dusts that contain crystalline silica have been associated directly or indirectly with the development of pneumoconiosis or silicosis, non-malignant respiratory diseases, lung cancer, and other diseases. The health impacts on workers with silica mixed dust exposure in tin mines and dose-response rela...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20248
更新日期：2006-02-01 00:00:00
abstract：OBJECTIVE:To investigate the one-year prevalence of musculoskeletal symptoms and associated risk factors in a large sample of Chinese workers in various industrial settings. METHODS:A total of 5,338 (3,632 males and 1,706 females) workers from 13 companies participated in this study. Musculoskeletal symptoms in differ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.21037
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND:The use of biopesticides in agriculture may implicate new risks of work-related allergic reactions. METHODS:Sera were tested from the BIOGART project, a longitudinal respiratory health study among >300 Danish greenhouse workers. IgE was measured by enzyme immunoassay (EIA) with extracts of biopesticide prod...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20086
更新日期：2004-10-01 00:00:00
abstract：:Currently available computerized hospital records from four hospitals in Southwest Oregon were utilized for occupational health surveillance by administering brief occupational questionnaires to hospitalized male patients. Patients with occupational exposure to the lumber and wood products industries showed statistica...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700040605
更新日期：1983-01-01 00:00:00
abstract：:Pressure from the vinyl chloride (VC) industry on researchers involved in industry-sponsored studies and on regulatory agencies has been documented since 1970s. This commentary describes the influence of a lawsuit pursued by workers of an Italian VC plant on the recent scientific debate on VC exposure and risk of hepa...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20941
更新日期：2011-06-01 00:00:00
abstract：:The cause-specific mortality (1940-1993) of 2,985 male workers employed in three oil refineries was examined using a proportionate mortality study design. Separate analyses were undertaken by race, refinery, employment status (active and retired), and time since entry into the Oil, Chemical, and Atomic Workers (OCAW) ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(199804)33:4<327::aid-ajim3
更新日期：1998-04-01 00:00:00
abstract：BACKGROUND:Despite being preventable, work-related upper extremity cumulative trauma disorders (UECTDs) remain problematic. This study is unique in its focus on predictors of employer risk-reduction activities (ERRAs) in response to a UECTD case. METHODS:Workers' compensation claimants (N = 537) completed a telephone ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/1097-0274(200011)38:5<489::aid-ajim1>3.0.c
更新日期：2000-11-01 00:00:00
abstract：:Dermatological disorders in athletes may occur as a result of repeated mechanical trauma, physical and chemical agents, climatic conditions, infections, infestations, and exacerbations of pre-existing skin disorders. These include black heel, tennis toe and other causes of subungual hemorrhage, friction blisters, abra...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700080422
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND:Around the globe, work has a heavy impact on health. To better advise policy makers, we assessed the global burden of disease and injury due to selected occupational hazards. This article presents an overview, and describes the methodology employed in the companion studies. METHODS:Using the World Health Or...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20211
更新日期：2005-12-01 00:00:00
abstract：:In a survey of chronic respiratory symptoms and airflow obstruction of a rural population aged 20-65 years, the effects of both farming and, in particular, the exposure to grain dust on the respiratory health of the people was examined. Of the 1,892 subjects (82% of the eligible population) studied, 924 were males and...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700150103
更新日期：1989-01-01 00:00:00
abstract：:Ethylene oxide was tested in environmental air and in the alveolar air of 10 workers employed in a hospital sterilizer unit at hourly intervals during the work shift. Alveolar ethylene oxide concentrations (Ca) were correlated with environmental concentration (Ci) in all the workers studied (r = 0.89-0.99). The ratio ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700080109
更新日期：1985-01-01 00:00:00
abstract：:Limitations on the use of full halogenated chlorofluorocarbons (CFCs) may create occupational environmental problems. These are currently largely unknown, because the toxicology of most CFC substitutes is unknown. Therefore, toxicity testing of CFC substitutes is necessary, and this can best be done before their use c...
journal_title：American journal of industrial medicine
pub_type： 杂志文章,评审
doi：10.1002/ajim.4700190615
更新日期：1991-01-01 00:00:00
abstract：:This study uses the National Mortality Followback Survey of 1986 to identify the top five Sentinel Health Events Occupational [SHE(O)s], the five leading causes of death, and to ascertain the primary occupations and industries associated with these. We found that, as expected, cardiovascular diseases were four of the ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700270205
更新日期：1995-02-01 00:00:00
abstract：BACKGROUND:Case reports have identified hydrofluoric acid (HF) as causing fatal work injury, and HF has both local and systemic toxicity. Surveillance for HF-related mortality is problematic because of the lack of unique coding for this acid in hospital records and vital statistics. METHODS:We identified HF-related fa...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.1090
更新日期：2001-08-01 00:00:00
abstract：:The objective of this study was to examine the endocrine profiles of a group of male workers chronically exposed to trichloroethylene (TCE) in an electronics factory. A total of 124 workers participated in a preliminary study, for which 85 satisfied the selection criteria and were recruited to take part in a more deta...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/(sici)1097-0274(199709)32:3<217::aid-ajim6
更新日期：1997-09-01 00:00:00
abstract：OBJECTIVES:Few Canadian data sources allow the examination of disparities by ethnicity, language, or immigrant status in occupational exposures or health outcomes. However, it is possible to document the mechanisms that can create disparities, such as the over-representation of population groups in high-risk jobs. We e...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20845
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to investigate the association between dynamic thiol/disulphide homeostasis and occupational exposure to volatile anesthetic gases in operating theater personnel. Decreased blood thiol levels and raised blood disulphide levels serve as biomarkers of oxidative stress. METHODS:We...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.22764
更新日期：2017-11-01 00:00:00
abstract：:Surveillance of pregnancy loss as a way to detect hazardous exposures is attractive in principle. However, there are no established methods for monitoring pregnancy loss in humans. Surveillance is difficult because most loss occurs within the first 12 weeks of gestation, when pregnancy may not be documented or even re...
journal_title：American journal of industrial medicine
pub_type： 杂志文章,评审
doi：
更新日期：1983-01-01 00:00:00
abstract：BACKGROUND:The aim of this study was to compile nationally representative statistics describing inpatient hospital care for patients with work-related injuries and illnesses covered under workers' compensation (WC) insurance in the United States. METHODS:Three years of data (1997-1999) from the Nationwide Inpatient Sa...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.10273
更新日期：2003-10-01 00:00:00
abstract：:Observations on an increased spontaneous abortion rate initiated a study among personnel working at a laboratory for diagnostic virology. Personnel at a bacteriological laboratory and at another virological laboratory served as controls. Seventy-seven female employees at the laboratory for virology were interviewed, a...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700010203
更新日期：1980-01-01 00:00:00
abstract：:There have long been case reports linking silica exposure to a variety of autoimmune diseases (systemic sclerosis, rheumatoid arthritis, lupus, chronic renal disease). Evidence of this association in larger epidemiologic studies has been increasing in the last decade. We summarize this evidence here, and present some ...
journal_title：American journal of industrial medicine
pub_type： 杂志文章,评审
doi：10.1002/ajim.4700280505
更新日期：1995-11-01 00:00:00
abstract：BACKGROUND:Self-reported exposure to secondhand smoke (SHS) has been associated with elevated inflammatory markers in adults. The association between SHS indicated by serum cotinine and markers of inflammation has not been investigated in adult workers. METHODS:Using the subpopulation of employed participants (20 year...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20591
更新日期：2008-08-01 00:00:00
abstract：:A model was created to assess occupational exposure to extremely low-frequency magnetic fields (ELF-MF) among semiconductor fabrication-room (fab) workers. This model was based on the assumption that each subject's exposure arose from being near identifiable ELF-MF sources or being in areas with high ELF-MF levels. To...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700280608
更新日期：1995-12-01 00:00:00
abstract：:Heat stress is a recognized occupational hazard in aluminum smelter pot rooms. This is the report of an unusual and complex case of heat-related illness in an aluminum smelter worker. The 34-year-old male US worker developed life-threatening heat-related illness in August 2018, on his first day back at work after a 7-...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.23061
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Community Participatory Approach to Measuring Farmworker Pesticide Exposure, PACE3, used a longitudinal design to document pesticide biomarkers among farmworkers. This article presents an overview of PACE3 and provides a descriptive analysis of participant characteristics and one set of pesticide biomarkers,...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.20703
更新日期：2009-07-01 00:00:00
abstract：:Thirty-six car painters and 115 control persons participated in a follow-up investigation 6 years after the initial study, including measurement of lung function (dynamic spirometry and nitrogen washout test) and estimation of exposure to diisocyanates based on individual working routines, use of respiratory protectio...
journal_title：American journal of industrial medicine
pub_type： 杂志文章
doi：10.1002/ajim.4700170302
更新日期：1990-01-01 00:00:00
