Advances in optical imaging of biomedical media.

Abstract:

:In this article, we have presented an overview of fundamental issues involved in mediphotonic imaging, and reviewed some of the emerging techniques for early-light transillumination imaging of body organs. The results on human breast tissues presented here, together with the data accumulated and advances made by researchers around the globe, not only demonstrate the feasibility of optical imaging as a clinical procedure but indicate a road map to reach that goal. The milestones include evaluation of relative merits of available approaches for a particular imaging application; selection of diagnostic wavelengths, as well as sources to generate and detectors to monitor light at those wavelengths; accumulation of data on optical, spectroscopic, and transport properties of tissues and organs; in vivo testing; prototype instrumentation development; clinical trials; governmental approval; cost analysis and marketing; and finally system improvement based on feedback from end users. A new era of optical clinical imaging is at the door.

journal_name

Ann N Y Acad Sci

authors

Alfano RR,Demos SG,Gayen SK

doi

10.1111/j.1749-6632.1997.tb46200.x

subject

Has Abstract

pub_date

1997-05-30 00:00:00

pages

248-70; discussion 271

eissn

0077-8923

issn

1749-6632

journal_volume

820

pub_type

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