Abstract:
:In this article, we have presented an overview of fundamental issues involved in mediphotonic imaging, and reviewed some of the emerging techniques for early-light transillumination imaging of body organs. The results on human breast tissues presented here, together with the data accumulated and advances made by researchers around the globe, not only demonstrate the feasibility of optical imaging as a clinical procedure but indicate a road map to reach that goal. The milestones include evaluation of relative merits of available approaches for a particular imaging application; selection of diagnostic wavelengths, as well as sources to generate and detectors to monitor light at those wavelengths; accumulation of data on optical, spectroscopic, and transport properties of tissues and organs; in vivo testing; prototype instrumentation development; clinical trials; governmental approval; cost analysis and marketing; and finally system improvement based on feedback from end users. A new era of optical clinical imaging is at the door.
journal_name
Ann N Y Acad Scijournal_title
Annals of the New York Academy of Sciencesauthors
Alfano RR,Demos SG,Gayen SKdoi
10.1111/j.1749-6632.1997.tb46200.xsubject
Has Abstractpub_date
1997-05-30 00:00:00pages
248-70; discussion 271eissn
0077-8923issn
1749-6632journal_volume
820pub_type
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