DTI of human skeletal muscle: the effects of diffusion encoding parameters, signal-to-noise ratio and T2 on tensor indices and fiber tracts.

abstract：:The steady-state distribution of the general anesthetic halothane in different rat tissues, including a renal adenocarcinoma with and without hyperthermia treatment, has been evaluated by in vivo 19F NMR spectroscopy. The 19F spectra of halothane (which is a hydrophobic probe) from within tissue show differences in th...

journal_title：NMR in biomedicine

authors： Burt CT,Moore RR,Roberts MF

更新日期：1993-09-01 00:00:00

abstract：:The accurate diagnosis of glioma subtypes is critical for appropriate treatment, but conventional histopathologic diagnosis often exhibits significant intra-observer variability and sampling error. The aim of this study was to investigate whether histogram analysis using an automatically segmented region of interest (...

journal_title：NMR in biomedicine

authors： Lee J,Choi SH,Kim JH,Sohn CH,Lee S,Jeong J

更新日期：2014-09-01 00:00:00

abstract：:Qualitative and quantitative (1) H NMR analysis of lipid extracts of gallbladder tissue in chronic cholecystitis (CC, benign) (n = 14), xanthogranulomatous cholecystitis (XGC, intermediate) (n = 9) and gallbladder cancer (GBC, malignant) (n = 8) was carried out to understand the mechanisms involved in the transformati...

journal_title：NMR in biomedicine

authors： Jayalakshmi K,Sonkar K,Behari A,Kapoor VK,Sinha N

更新日期：2011-05-01 00:00:00

abstract：:The background underpinning the clinical use of ultrashort echo time, SPRITE and other pulse sequences for imaging bone and other connective tissues with short T2 is reviewed. Features of the basic physics relevant to UTE imaging are described, including the consequences when the radiofrequency pulse duration is of th...

journal_title：NMR in biomedicine

authors： Robson MD,Bydder GM

更新日期：2006-11-01 00:00:00

abstract：:The physiological status of anesthetized rats greatly influences blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI). Monitoring of physiological parameters, particularly partial pressure of carbon dioxide (pCO(2)) levels in the blood, is therefore an important part in the design and ...

journal_title：NMR in biomedicine

authors： Ramos-Cabrer P,Weber R,Wiedermann D,Hoehn M

更新日期：2005-11-01 00:00:00

abstract：:In recent years considerable effort has been devoted to applying pattern recognition techniques to the complex task of data analysis in magnetic resonance spectroscopy. It may be argued that such techniques will facilitate putting MRS technology to practical clinical use. This paper reviews approaches of pattern recog...

journal_title：NMR in biomedicine

authors： el-Deredy W

更新日期：1997-05-01 00:00:00

abstract：:Quantitative susceptibility mapping (QSM) is a recently developed MRI technique that provides a quantitative measure of tissue magnetic susceptibility. To compute tissue magnetic susceptibilities based on gradient echoes, QSM requires reliable unwrapping of the measured phase images and removal of contributions caused...

journal_title：NMR in biomedicine

authors： Li W,Avram AV,Wu B,Xiao X,Liu C

更新日期：2014-02-01 00:00:00

abstract：:The temporary or permanent storage of human bodies in freezers following a homicide is a documented method for criminal disposal of human corpses. In these cases, the detection of characteristics which indicate that a thawed cadaver or body part was previously frozen provides crucial information for forensic casework....

journal_title：NMR in biomedicine

authors： Gascho D,Richter H,Karampinos DC,Heimer J,Schaerli S,Thali MJ,Zoelch N

更新日期：2020-02-01 00:00:00

abstract：:Chemical exchange saturation transfer (CEST) potentially provides the ability to detect small solute pools through indirect measurements of attenuated water signals. However, CEST effects may be diluted by various competing effects, such as non-specific magnetization transfer (MT) and asymmetric MT effects, water long...

journal_title：NMR in biomedicine

authors： Li H,Zu Z,Zaiss M,Khan IS,Singer RJ,Gochberg DF,Bachert P,Gore JC,Xu J

更新日期：2015-02-01 00:00:00

abstract：:Glucose metabolism in control and estrogen stimulated rat uteri was investigated using 13C NMR spectroscopy. By employing an NMR adapted perifusion system, and developing protocols and methods based on the application of [1-13C]glucose labeling, it was possible to measure, with a temporal resolution of 10 min, the kin...

journal_title：NMR in biomedicine

authors： Shinkarenko L,Kaye AM,Degani H

更新日期：1994-08-01 00:00:00

abstract：:Here, we show that the sensitivity of (31)P MRSI of (31)P spins J-coupled to protons can be increased by almost a factor of three when compared with an optimal direct detection free induction decay. By direct detection integrated with multi-echo polarization transfer (DIMEPT), multiple signals from polarization transf...

journal_title：NMR in biomedicine

authors： van der Kemp WJ,Boer VO,Luijten PR,Klomp DW

更新日期：2014-10-01 00:00:00

abstract：:Under normal conditions, the heart mainly relies on fatty acid oxidation to meet its energy needs. Changes in myocardial fuel preference are noted in the diseased and failing heart. The magnetic resonance signal enhancement provided by spin hyperpolarization allows the metabolism of substrates labeled with carbon-13 t...

journal_title：NMR in biomedicine

authors： Yoshihara HAI,Bastiaansen JAM,Karlsson M,Lerche MH,Comment A,Schwitter J

更新日期：2020-03-01 00:00:00

abstract：:The application of 31P MR spectroscopy in the characterization and treatment of malignant human extremity tumors is reviewed and placed in the perspective of results obtained in murine sarcomas. Despite the now widespread acquisition of gradient localized spectral maps, the low spatial resolution that can be achieved ...

journal_title：NMR in biomedicine

authors： Sijens PE

更新日期：1998-11-01 00:00:00

abstract：:The goal of this study was to validate metabolite quantification at short TE, with particular focus on how to best account for the macromolecular signal contribution. A robust, short-TE PRESS protocol is presented, which allows reliable quantification, in vivo, of metabolite signals at 3 T in human brain. Water suppre...

journal_title：NMR in biomedicine

authors： Gottschalk M,Lamalle L,Segebarth C

更新日期：2008-06-01 00:00:00

abstract：:Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) and proton (1H) magnetic resonance spectroscopy (MRS) provide structural and biochemical information, including vascular volume, vascular permeability and tissue metabolism. In this study, we performed analysis of the enhancement characteristic from DCE-...

journal_title：NMR in biomedicine

authors： Lipnick S,Liu X,Sayre J,Bassett LW,Debruhl N,Thomas MA

更新日期：2010-10-01 00:00:00

abstract：:A recent analysis of the optimization of magnetization transfer experiments to estimate first-order rate constants is extended to the design of experiments for measuring these constants and T1 when both parameters are initially unknown. When the number of measurement times is fixed, an optimal design will consist of a...

journal_title：NMR in biomedicine

authors： Katki H,Weiss GH,Kiefer JE,Taitelbaum H,Spencer RG

更新日期：1996-05-01 00:00:00

abstract：:The dependence of apparent diffusion coefficients (ADCs) of molecules in biological tissues on an acquisition-specific timescale is a powerful mechanism for studying tissue microstructure. Unlike water, metabolites are confined mainly to intracellular compartments, thus providing higher specificity to tissue microstru...

journal_title：NMR in biomedicine

authors： Branzoli F,Ercan E,Webb A,Ronen I

更新日期：2014-05-01 00:00:00

abstract：:To assess infarction development in pig hearts, Mn-enhanced and Gd-enhanced MRI were used. In domestic pigs (25-35 kg, n = 37), the first and second diagonal branches of the left anterior descending coronary artery were ligated to induce acute ischemia and infarction (ischemia+reperfusion) or chronic infarction of inc...

journal_title：NMR in biomedicine

authors： Yang Y,Gruwel ML,Sun J,Gervai P,Yang X,Kupriyanov VV

更新日期：2009-02-01 00:00:00

abstract：:During magnetic resonance imaging (MRI) examinations, the average specific absorption rate (SAR) of the whole body is calculated as an index of global energy deposition in biological tissue without taking into account the presence of metallic implants or conductive materials. However, this global SAR calculation is no...

journal_title：NMR in biomedicine

authors： Saniour I,Gaborit G,Perrier AL,Gillette L,Revillod G,Sablong R,Duvillaret L,Beuf O

更新日期：2018-01-01 00:00:00

abstract：:This study tests the hypothesis that brief periods of ischemia result in an increase in myocardial lipids during early reperfusion. We conducted 1H NMR spectroscopy to serially measure myocardial lipids before and after regional ischemia. Localized 1H NMR spectra (spatial resolution of 1.25 mm) were obtained using a o...

journal_title：NMR in biomedicine

authors： Balschi JA,Hetherington HP,Bradley EL Jr,Pohost GM

更新日期：1995-04-01 00:00:00

abstract：:Citicoline supplementation has been used to ameliorate memory disturbances in older people and those with Alzheimer's disease. This study used MRS to characterize the effects of citicoline on high-energy phosphate metabolites and constituents of membrane synthesis in the frontal lobe. Phosphorus ((31)P) metabolite dat...

journal_title：NMR in biomedicine

authors： Silveri MM,Dikan J,Ross AJ,Jensen JE,Kamiya T,Kawada Y,Renshaw PF,Yurgelun-Todd DA

更新日期：2008-11-01 00:00:00

abstract：:(31)P MRS provides a unique non-invasive window into myocardial energy homeostasis. Mouse models of cardiac disease are widely used in preclinical studies, but the application of (31)P MRS in the in vivo mouse heart has been limited. The small-sized, fast-beating mouse heart imposes challenges regarding localized sign...

journal_title：NMR in biomedicine

authors： Bakermans AJ,Abdurrachim D,van Nierop BJ,Koeman A,van der Kroon I,Baartscheer A,Schumacher CA,Strijkers GJ,Houten SM,Zuurbier CJ,Nicolay K,Prompers JJ

更新日期：2015-10-01 00:00:00

abstract：:Tumor metabolism is directly coupled to tumor blood flow (TBF) and both metabolism and blood flow may be determinants of tumor response to treatment. Since NMR has been used extensively to monitor tumor metabolism noninvasively, development of NMR-based methods for TBF measurement was motivated by the desire to examin...

journal_title：NMR in biomedicine

authors： Evelhoch JL

更新日期：1992-09-01 00:00:00

abstract：:Despite 40 years of NMR spectroscopy and 10 years of in vivo spectroscopy in humans, the break-even point for routine clinical diagnosis has not yet been reached. Obviously there are many factors that stimulate but also restrict the use of proton NMR spectroscopy in clinical routine. ...

journal_title：NMR in biomedicine

authors： Moser E

更新日期：1994-12-01 00:00:00

abstract：:Perfusion is an important biomarker of tissue function and has been associated with tumor pathophysiology such as angiogenesis and hypoxia. Arterial spin labeling (ASL) MRI allows noninvasive and quantitative imaging of perfusion; however, the application in mouse xenograft tumor models has been challenging due to the...

journal_title：NMR in biomedicine

authors： Rajendran R,Liang J,Tang MY,Henry B,Chuang KH

更新日期：2015-08-01 00:00:00

abstract：:Hyperglycemia (blood glucose concentration >150 mg/dL) is common in extremely low gestational age newborns (ELGANs; birth at <28 week gestation). Hyperglycemia increases the risk of brain injury in the neonatal period. The long-term effects are not well understood. In adult rats, hyperglycemia alters hippocampal energ...

journal_title：NMR in biomedicine

authors： Rao R,Nashawaty M,Fatima S,Ennis K,Tkac I

更新日期：2018-05-01 00:00:00

abstract：:Glycine (Gly) has been implicated in several neurological disorders, including malignant brain tumors. The precise measurement of Gly is challenging largely as a result of the spectral overlap with myo-inositol (mI). We report a new triple-refocusing sequence for the reliable co-detection of Gly and mI at 3 T and for ...

journal_title：NMR in biomedicine

authors： Tiwari V,An Z,Ganji SK,Baxter J,Patel TR,Pan E,Mickey BE,Maher EA,Pinho MC,Choi C

更新日期：2017-09-01 00:00:00

abstract：:This paper compares two spectral processing methods for obtaining quantitative measures from in vivo prostate spectra, evaluates their effectiveness, and discusses the necessary modifications for accurate results. A frequency domain analysis (FDA) method based on peak integration was compared with a time domain fittin...

journal_title：NMR in biomedicine

authors： Pels P,Ozturk-Isik E,Swanson MG,Vanhamme L,Kurhanewicz J,Nelson SJ,Van Huffel S

更新日期：2006-04-01 00:00:00

abstract：:Acute kidney injury (AKI) in mice caused by sustained ischemia followed by reperfusion is associated with acute tubular necrosis and renal dysfunctional blood flow. Although the principal role of the kidney is the maintenance of acid-base balance, current imaging approaches are unable to assess this important paramete...

journal_title：NMR in biomedicine

authors： Longo DL,Cutrin JC,Michelotti F,Irrera P,Aime S

更新日期：2017-07-01 00:00:00

abstract：:A special characteristic of the brain is the usage of lactate as alternative fuel instead of glucose to preserve its energy homeostasis. This physiological function is valid for sufficient cerebral glucose supply, as well as presumably during hypoglycemia, given that exogenous lactate infusion suppresses hormonal coun...

journal_title：NMR in biomedicine

authors： Richter J,Rabe D,Duysen K,Melchert UH,Oltmanns KM

更新日期：2019-11-01 00:00:00