Abstract:
:This study applies metabolic flux network analysis (MFA) to evaluate the metabolic flux of fermentative hydrogen production (FHP) with the use of Clostridium tyrobutyricum fed with either glucose or lactate/acetate as substrates. The MFA results suggest that hydraulic retention time (HRT) presents significant impact on hydrogen production from glucose. At HRT between 4 and 18 h, increase of HRT increased hydrogen production but decreased lactate production, while at HRT below 4 h decrease of HRT increased hydrogen production but decreased lactate production. The flux for lactate, butyrate and acetate seemed to affect H₂ production, due presumably to their impacts on the balance of NADH, ferredoxin and ATP. It is suggested that the MFA can be a useful tool to provide valuable information for optimization and design of the fermentative hydrogen production process.
journal_name
Bioresour Technoljournal_title
Bioresource technologyauthors
Cheng HH,Whang LM,Lin CA,Liu IC,Wu CWdoi
10.1016/j.biortech.2013.03.141subject
Has Abstractpub_date
2013-08-01 00:00:00pages
233-9eissn
0960-8524issn
1873-2976pii
S0960-8524(13)00527-0journal_volume
141pub_type
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