Abstract:
:Interstitial cystitis is a chronic benign disease of the bladder that causes bothersome and debilitating symptoms and mainly affects women. Since interstitial cystitis (IC) might result from a defective glycosaminoglycan layer of the bladder epithelium, we conducted a trial of hyaluronic acid (HA), used intravesically, to test its activity in the treatment of this disease. A total of 10 patients with typical findings of IC were included. Following bladder catheterisation, the patients received a dose of 40 mg, weekly for 6 weeks, and then monthly. Response to therapy was evaluated by comparing the pre-treatment and post-treatment symptom scores and voiding diaries. There was a 30% positive response rate at week 6, which was maintained until week 24. No significant local or general side-effects were noted during the course of treatment. Although we recorded a low incidence of success in our group of patients, the results of our limited study were satisfactory in the group of responsive patients (30%), who had no relapses during the observation period of 6 months. The intravesical administration of HA was well tolerated in all cases.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Porru D,Campus G,Tudino D,Valdes E,Vespa A,Scarpa RM,Usai Edoi
10.1159/000283012subject
Has Abstractpub_date
1997-01-01 00:00:00pages
26-9issue
1eissn
0042-1138issn
1423-0399journal_volume
59pub_type
杂志文章abstract::A partial urethral obstruction was induced in female rats. After 6 weeks, detrusor weight had increased eightfold and collagen concentration had decreased to about 40% compared to controls. Due to the weight gain, the total amount of detrusor collagen had increased more than threefold. Removal of the obstruction led t...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282230
更新日期:1991-01-01 00:00:00
abstract:INTRODUCTION:The use of cadaveric pediatric kidneys has been suggested as a means to overcome organ shortage, but is debated because of technical complications and an increased incidence of functional allograft impairment. METHODS:We experienced 2 cases of cadaveric renal transplantation from a non-heart-beating pedia...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000068778
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Elevated serum C-reactive protein (CRP) level has been demonstrated to predict poorer survival of both localized and metastatic renal cell carcinoma. However, the prognostic value of intratumoral CRP expression has not been sufficiently studied. PATIENTS AND METHODS:In the present study, the expression of C...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000353401
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:This meta-analysis was to assess solifenacin and tolterodine in patients with overactive bladder. METHODS:We searched PubMed, the Cochrane Library, EMBASE, CNKI, Wanfang, and ClinicalTrials.gov databases for randomized controlled trials (RCTs). The efficacy endpoint was daily micturition frequency, daily ur...
journal_title:Urologia internationalis
pub_type: 杂志文章,meta分析
doi:10.1159/000497311
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:Nearly 80% of the patients suffering from advanced stages of prostate cancer in Germany are treated currently with luteinizing hormone-releasing hormone (LH-RH) analogs alone or in combination with androgen receptor antagonists. The aim of this study was to assess whether the prescription practice for LH-R...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000096334
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Radical cystectomy (RC) still poses a significant risk for mortality and morbidity. OBJECTIVES:We compared in-hospital outcomes after RC in the United States and -Germany using population-based data. METHODS:We compared data from the US Nationwide Inpatient Sample to the German hospital billing database. M...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000496347
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:Clear cell renal cell carcinoma (ccRCC) is the most common kidney tumor. If feasible, metastasectomy is preferably indicated in metastatic disease. OBJECTIVE:The aim of this study was to determine the outcome of patients after pulmonary metastasectomy (PM). METHODS:PM for ccRCC was performed in 35 patien...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000502493
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:This study aimed to evaluate the role of bone scan as a staging investigation in newly diagnosed untreated prostate cancers. MATERIALS AND METHODS:Bone scan results in patients with newly diagnosed prostate cancer were reviewed and correlated with clinical stage, prostate-specific antigen (PSA) and Gleason s...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000091620
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:Chronic renal damage due to tubulointerstitial fibrosis is one of several complications of posterior urethral valves in a significant number of children. As activation of the renin-angiotensin system plays an important role in this injury, we conducted this study to investigate whether administration of captopr...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000098078
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:IL-6 has been reported to be a significant prognostic factor for prostate cancer and induces synthesis of C-reactive protein (CRP) by hepatocytes. The present study was undertaken to evaluate the clinical value of serum CRP in prostate cancer patients with metastases. METHODS:The prognostic significance of ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000112601
更新日期:2008-01-01 00:00:00
abstract::Negotiating a tortuous or obstructed ureter with a wire can be time-consuming and sometimes tiring. The principle of using a slippery floppy wire and then replacing it with a stiff wire through a 5-french open-ended ureteral catheter yields a high success rate. The ureteral catheter can be used for a radiocontrast stu...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282713
更新日期:1995-01-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to analyze the influence of residents' participation in flexible ureteroscopy (fURS) on intra- and postoperative outcomes. MATERIALS AND METHODS:Intra- and postoperative parameters were compared in a retrospective monocentric setting between 3 groups: "resident group" (47 cases) ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000504989
更新日期:2020-01-01 00:00:00
abstract:AIMS:To study the effects of left gonadal vein ligation on semen parameters and venous hemodynamics of the testis. SUBJECTS AND METHODS:All male voluntary kidney donors who were scheduled to have left donor nephrectomy between March 2004 and February 2005, by either open or laparoscopic technique, were considered for ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000277603
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:We aimed at evaluating the incidence of lymphoceles, a common complication after radical retropubic prostatectomy (RRP), at a high volume centre, define risk factors and assess the clinical outcome. MATERIALS AND METHODS:454 patients receiving RRP and pelvic lymph node dissection were assessed for postope...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000381463
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:We aimed to assess the diagnostic accuracy of radiolabeled prostate-specific membrane antigen positron emission tomography (PSMA PET) or positron emission tomography/computed tomography (PET/CT) for primary lymph node (LN) staging in newly diagnosed intermediate to high-risk prostate cancer (PCa) patients....
journal_title:Urologia internationalis
pub_type: 杂志文章,meta分析
doi:10.1159/000493169
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To investigate patients' opinions on the degree of pain during shock wave lithotripsy, and the need for analgesics in patients with urinary stone. METHODS:A prospective questionnaire study involving subjective pain assessment during and just after shock wave lithotripsy was performed in consecutive patients ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000082710
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:Partial unilateral ureteral obstruction (PUUO) is the type of obstruction that is most often encountered in pediatric clinical practice. The majority of our knowledge on PUUO has been derived from experimental studies and the effects of PUUO on the kidney have still been a source of continual investigation...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000111736
更新日期:2008-01-01 00:00:00
abstract::Ischemia, induced by atherosclerosis, is a common cause of disorders in the elderly. Bladder dysfunction in older people may be caused by detrusor ischemia. We compared blood flow to the bladder and detrusor function in vivo and in vitro in young (6-month-old) and aged (24-month-old) male Sprague-Dawley rats. In both ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030365
更新日期:1999-01-01 00:00:00
abstract:AIM:To evaluate the efficacy of a new sclerotization technique with pure ethanol in the treatment of symptomatic renal cysts. PATIENTS AND METHODS:Fourteen patients having renal cysts with a meant diameter of 10 (range 5-15) cm were treated. Our technique includes: ultrasound-guided percutaneous puncture with an 18-ga...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000071846
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Laparoscopic adrenalectomy is the gold standard for treatment of benign adrenal lesions. Tumor size is a factor that might influence decision-making concerning the use of laparoscopic approach. The aim of this study was to analyze the results of adrenalectomy for tumors ≥6 cm in diameter. METHODS:Two groups...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000444146
更新日期:2016-01-01 00:00:00
abstract::Recordings of local pressure within the membranous urethra were performed in 15 male spinal cord injury patients before and after external sphincterotomy. Transurethral division of the external sphincter reduced the intraurethral pressure by 55% in the upper part of the membranous urethra and by 66% in the lower part....
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000279962
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to assess the occurrence of ectopic remnants of adrenal cortex tissue encountered in pediatric patients who underwent groin surgical explorations. MATERIALS AND METHODS:We studied 1,862 patients with groin surgical explorations during a period of 12 consecutive years (1995-20...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000151411
更新日期:2008-01-01 00:00:00
abstract:AIM:To determine efficacy and clinical predictors of stone fragmentation when using slow-rate shock wave lithotripsy (SWL). PATIENTS AND METHODS:In total, 116 patients with radiopaque urinary tract stones were randomized into two groups: 57 patients were treated with SWL at 90 shocks/min, and 59 patients were treated ...
journal_title:Urologia internationalis
pub_type: 杂志文章,随机对照试验
doi:10.1159/000106324
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:To investigate whether or not the age of spontaneous resolution of monosymptomatic nocturnal enuresis (MNE) was familial. PATIENTS AND METHODS:A questionnaire was administered to more than 1,500 people, and 100 appropriate participants were identified from four referral hospitals. We included the participants ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000370166
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:We aimed at evaluating the efficacy of extracorporeal shockwave lithotripsy (SWL) for treating distal ureteral calculi performed in supine vs. prone position. MATERIALS AND METHODS:Eligible studies were identified by 2 reviewers using PubMed, Embase, and Web of Science databases. Outcomes included stone-free r...
journal_title:Urologia internationalis
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000439140
更新日期:2016-01-01 00:00:00
abstract:INTRODUCTION:Epididymitis is an inflammation or infection of the epididymis, a convoluted duct that lies on the posterior surface of the testicle. Oxidative stress due to excessive production of reactive oxygen species in epididymitis, impaired antioxidant defense mechanisms, or both, precipitates a range of pathologie...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000092063
更新日期:2006-01-01 00:00:00
abstract::The effects of ammonium chloride, methenamine hippurate and ascorbic acid on urinary pH was studied in 14 normal subjects. A statistically significant reduction of urinary pH was recorded with ammonium chloride in daily doses of 1.5 and 3 g, but not with 2 g of methenamine hippurate or 1.8 g of ascorbic acid. Long-ter...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281732
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Cyclooxygenase-2 (COX-2) is a key enzyme involved in the production of prostaglandins and its inhibitors have been shown to induce apoptosis in a variety of cancer cells. We reasoned that combination treatment of renal cell carcinoma (RCC) cells with COX-2 inhibitors and anticancer agents may result in syner...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000288243
更新日期:2010-01-01 00:00:00
abstract::Carcinoembryonic antigen (CEA) is elevated in urine and/or serum of patients with transitional cell carcinoma (TCC) of the urinary bladder. A group of 26 patients with TCC of the urinary bladder were evaluated with regard to urine/serum CEA levels and CEA tissue content. CEA could be detected in normal, metaplastic an...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280875
更新日期:1983-01-01 00:00:00
abstract:EPIDEMIOLOGY:The annual incidence of urolithiasis in the population is at least 0.1%. In rural areas, there are remarkably less actual stone formers than in urban districts, and also vegetarians show less stone diseases. Calcium carbonate as a urinary calculus compound is not in the strict sense impossible, but often a...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280781
更新日期:1981-01-01 00:00:00