Retinoic acid receptors alpha, beta and gamma, and cellular retinol binding protein-I expression in breast fibrocystic disease and cancer.

abstract：:Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders resulting from deficiency of one of the five enzymes required for synthesis of cortisol in the adrenal cortex. The most common form of the disease is classic 21-hydroxylase deficiency, which is characterized by decreased synthesis of gluc...

journal_title：European journal of endocrinology

authors： Charmandari E,Brook CG,Hindmarsh PC

更新日期：2004-11-01 00:00:00

abstract：:Exogenous growth hormone (hGH) administration in humans attenuates the endogenous growth hormone (GH) response to some pharmacological stimuli; in particular, pretreatment with hGH completely blocks the serum GH response to growth hormone-releasing hormone. In order to evaluate the mechanism(s) whereby opiods induce G...

journal_title：European journal of endocrinology

authors： Fanciulli G,Oliva O,Tomasi PA,Pala A,Bertoncelli A,Dettori A,Delitala G

更新日期：1996-01-01 00:00:00

abstract：:Hypothyroidism is associated with increased morbidity from cardiovascular disease, and an increase in serum osteoprotegerin (OPG) has recently been reported to be associated with the severity of coronary heart disease and cardiovascular mortality. The present study was designed to examine whether hypothyroidism causes...

journal_title：European journal of endocrinology

authors： Nagasaki T,Inaba M,Jono S,Hiura Y,Tahara H,Shirakawa K,Onoda N,Ishikawa T,Ishimura E,Nishizawa Y

更新日期：2005-03-01 00:00:00

abstract：:We report our experience in treating growth delay in boys with isolated growth hormone deficiency (IGHD) receiving biosynthetic human growth hormone. The study was performed in 15 boys with IGHD receiving GH. At the chronological age of 13.1 (1.1) years (SD), 13 were prepubertal, two were in early puberty and there wa...

journal_title：European journal of endocrinology

authors： Albanese A,Stanhope R

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:Evaluation of the efficiency of somatostatin analogues in the treatment of a mixed luteinizing hormone (LH)-, alpha-subunit-, prolactin (PRL)-secreting pituitary adenoma. DESIGN:A 30-year-old woman, with amenorrhaea-galactorrhaea, presented with a pituitary macroadenoma. The endocrine evaluation showed high ...

journal_title：European journal of endocrinology

authors： Saveanu A,Morange-Ramos I,Gunz G,Dufour H,Enjalbert A,Jaquet P

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Previous studies have suggested that infections are an important cause of death in patients with Addison's disease, but epidemiological studies on the frequency of infections in this population are lacking. OBJECTIVE:To assess and compare the incidence risk of infections in patients with primary adrenal ins...

journal_title：European journal of endocrinology

authors： Smans LC,Souverein PC,Leufkens HG,Hoepelman AI,Zelissen PM

更新日期：2013-03-15 00:00:00

abstract：OBJECTIVE:The evidence that stress may provoke Graves' hyperthyroidism in genetically susceptible subjects is substantial. Whether exposure to stress is related to the severity of thyrotoxicosis has not been studied. Advancing age is associated with not only less severe Graves' hyperthyroidism but also self-reported st...

journal_title：European journal of endocrinology

authors： Vos XG,Smit N,Endert E,Brosschot JF,Tijssen JG,Wiersinga WM

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:IGF1 is essential for human growth and mediates its effects through the type 1 IGF receptor (IGF1R). Our objective was to determine the frequency of certain previously reported IGF1R gene variants in the normal population and their effect on stature. DESIGN:A cross-sectional study was conducted in a populati...

journal_title：European journal of endocrinology

authors： Kansra AR,Dolan LM,Martin LJ,Deka R,Chernausek SD

更新日期：2012-12-01 00:00:00

abstract：:We report the clinical history and results of endocrine investigations in two brothers born to consanguineous parents, who presented with hypokalemia and arterial hypertension when they were aged 2 and 6 years. The hormonal serum assay results, including extremely low values for aldosterone and plasma renin activity, ...

journal_title：European journal of endocrinology

authors： Gourmelen M,Saint-Jacques I,Morineau G,Soliman H,Julien R,Fiet J

更新日期：1996-08-01 00:00:00

abstract：UNLABELLED:Chronic exposure to hypercortisolism has significant impact on patient's health and health-related quality of life (HRQoL), as demonstrated with generic questionnaires. We have developed a disease-generated questionnaire to evaluate HRQoL in patients with Cushing's syndrome (CS; CushingQoL). OBJECTIVE:Valid...

journal_title：European journal of endocrinology

authors： Webb SM,Badia X,Barahona MJ,Colao A,Strasburger CJ,Tabarin A,van Aken MO,Pivonello R,Stalla G,Lamberts SW,Glusman JE

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:Mutations in HESX1 represent a rare cause of GH deficiency (GHD) associated with a broad spectrum of other anomalies. We searched for causative mutations in a cohort of 244 Italian patients affected by combined and isolated GHD (IGHD). METHODS:The HESX1 gene-coding region and exon-intron boundaries were scre...

journal_title：European journal of endocrinology

authors： Vivenza D,Godi M,Faienza MF,Mellone S,Moia S,Rapa A,Petri A,Bellone S,Riccomagno S,Cavallo L,Giordano M,Bona G

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:In the field of fine-needle aspiration cytology, the category of suspicious for malignancy (SM) thyroid lesions, that bears 55-85% risk of malignant histology, is a challenging topic in which morphology alone is not always able to make a correct diagnosis. Recently, immunocytochemistry (ICC) has been referred...

journal_title：European journal of endocrinology

authors： Rossi ED,Martini M,Capodimonti S,Straccia P,Cenci T,Lombardi CP,Pontecorvi A,Larocca LM,Fadda G

更新日期：2013-05-02 00:00:00

abstract：CONTEXT:Both acromegaly and adult growth hormone deficiency (GHD) are associated with increased fracture risk. Sufficient data are lacking regarding cortical bone microarchitecture and bone strength, as assessed by microfinite element analysis (µFEA). OBJECTIVE:To elucidate both cortical and trabecular bone microarchi...

journal_title：European journal of endocrinology

authors： Silva PPB,Amlashi FG,Yu EW,Pulaski-Liebert KJ,Gerweck AV,Fazeli PK,Lawson E,Nachtigall LB,Biller BMK,Miller KK,Klibanski A,Bouxsein M,Tritos NA

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of long-term GH in GH-deficient adults, as predicted by IGF-I levels. METHODS:Patients received GH, 5 microg/kg per day for 1 Month and 10 microg/kg per day for another 12-30 Months. Changes in body composition, cardiac structure/function, serum lipids and quality of life were meas...

journal_title：European journal of endocrinology

authors： Ezzat S,Fear S,Gaillard RC,Gayle C,Marcovitz S,Mattioni T,Nussey S,Rees A,Svanberg E

更新日期：2003-12-01 00:00:00

abstract：:Activating mutations of G proteins, which are membrane signal transducers, have been associated recently with the development of various endocrine neoplasms. Mutations of two highly conserved codons, Arg201 and Gln227, in the alpha-subunit of the Gs protein, the adenylyl cyclase-stimulating protein, were first describ...

journal_title：European journal of endocrinology

authors： Gicquel C,Dib A,Bertagna X,Amselem S,Le Bouc Y

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVE:Many investigators believe that basal adrenal venous sampling (AVS) should be done simultaneously, whereas others opt for sequential AVS for simplicity and reduced cost. This study aimed to evaluate the concordance of sequential and simultaneous AVS methods. DESIGN AND METHODS:Between 1989 and 2015, bilatera...

journal_title：European journal of endocrinology

authors： Almarzooqi MK,Chagnon M,Soulez G,Giroux MF,Gilbert P,Oliva VL,Perreault P,Bouchard L,Bourdeau I,Lacroix A,Therasse E

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:We measured the total and nonphosphorylated insulin-like growth factor-binding protein (IGFBP)-1 concentrations in obese children to determine the effect of obesity on the status of IGFBP-1 phosphorylation. We also measured the serum levels of insulin, total and free IGF-I, and IGFBP-3 to investigate their re...

journal_title：European journal of endocrinology

authors： Kamoda T,Saitoh H,Nakahara S,Inudoh M,Hirano T,Matsui A

更新日期：1999-12-01 00:00:00

abstract：:Recombinant human GH has been licensed for use in adult patients with GH deficiency (GHD) for over 15 years. Early weight- and surface area-based dosing regimens were effective but resulted in supraphysiological levels of IGF1 and increased incidence of side effects. Current practice has moved towards individualised r...

journal_title：European journal of endocrinology

authors： Gasco V,Prodam F,Grottoli S,Marzullo P,Longobardi S,Ghigo E,Aimaretti G

更新日期：2013-02-20 00:00:00

abstract：:Amiodarone (AMD) is a powerful anti-arrhythmic drug used for the treatment of a wide variety of cardiac arrhythmias and its most striking feature is its high iodine content. Thyroid dysfunction is a limiting side-effect of the drug and both AMD-induced hypothyroidism (AIH) and AMD-induced thyrotoxicosis (AIT) are repo...

journal_title：European journal of endocrinology

authors： Pitsiavas V,Smerdely P,Boyages SC

更新日期：1999-03-01 00:00:00

abstract：Objective:Hypertension and symptoms of catecholamine excess are features of pheochromocytomas and paragangliomas (PPGLs). This prospective observational cohort study assessed whether differences in presenting features in patients tested for PPGLs might assist establishing likelihood of disease. Design and methods:Pati...

journal_title：European journal of endocrinology

authors： Geroula A,Deutschbein T,Langton K,Masjkur J,Pamporaki C,Peitzsch M,Fliedner S,Timmers HJLM,Bornstein SR,Beuschlein F,Stell A,Januszewicz A,Prejbisz A,Fassnacht M,Lenders JWM,Eisenhofer G

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:We have studied the effect of tryptophan on cellular [(125)I]tri-iodothyronine (T3) uptake by mouse thymocytes. MATERIALS AND METHODS:Mouse thymocytes (20 x 10(6 )cells/ml) were suspended in Krebs-Ringer solution buffered by Tris-HCl and incubation (23 degrees C at pH7.45+/-0.6), in the presence or absence o...

journal_title：European journal of endocrinology

authors： Centanni M,Canettieri G,Viceconti N,Sibilla R,Bei A,Andreoli M

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:Prevalence of non-alcoholic fatty liver disease (NAFLD) among children is increasing dramatically. It is unclear why some patients develop steatohepatitis (NASH), fibrosis and cirrhosis from steatosis, and others do not. A role for leptin has been claimed. This study aims to evaluate the relationship between ...

journal_title：European journal of endocrinology

authors： Nobili V,Manco M,Ciampalini P,Diciommo V,Devito R,Piemonte F,Comparcola D,Guidi R,Marcellini M

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Identification of pretreatment risk factors predicting relapse in patients with hyperthyroidism of Graves' disease after stopping anti-thyroid drugs (ATD) is decisive to guide therapeutic options. PURPOSE:We performed a systematic search and meta-analysis to study predictors for relapse after stopping ATD i...

journal_title：European journal of endocrinology

authors： Struja T,Fehlberg H,Kutz A,Guebelin L,Degen C,Mueller B,Schuetz P

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Adiponectin and resistin have been linked to inflammation, endothelial dysfunction, and/or insulin secretion or resistance. It remains to be elucidated which of these adipokines is associated primarily with biomarkers of all or only some of these categories, i.e. biomarkers of inflammation, endothelial dysfun...

journal_title：European journal of endocrinology

authors： Fargnoli JL,Sun Q,Olenczuk D,Qi L,Zhu Y,Hu FB,Mantzoros CS

更新日期：2010-02-01 00:00:00

abstract：:Little is known about patients with malignant digestive neuroendocrine tumours (MD-NETs). Although their incidence is increasing, MD-NETs remain a rare cancer, representing 1% of digestive cancers. Most MD-NETs are well-differentiated. MD-NET poorly differentiated carcinomas account for 20% of cases on average. Anatom...

journal_title：European journal of endocrinology

authors： Lepage C,Bouvier AM,Faivre J

更新日期：2013-03-15 00:00:00

abstract：OBJECTIVE:Recent trials suggest that using ergot-derived dopamine agonists such as cabergoline in the treatment of Parkinson's disease is associated with an increased risk of valvular heart disease. However, the dose of cabergoline used to treat hyperprolactinaemia is considerably less than that used in Parkinson's dis...

journal_title：European journal of endocrinology

authors： Wakil A,Rigby AS,Clark AL,Kallvikbacka-Bennett A,Atkin SL

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:Biallelic TSHR mutations cause congenital hypothyroidism (CH). Serum TSH levels of monoallelic mutation carriers range from normal to mildly elevated, and thus the size of its effect remains unclear. The objectives were to examine the association between monoallelic TSHR mutations and positivity at newborn sc...

journal_title：European journal of endocrinology

authors： Abe K,Narumi S,Suwanai AS,Adachi M,Muroya K,Asakura Y,Nagasaki K,Abe T,Hasegawa T

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Somatostatin analogs (SA) are the cornerstone in the medical treatment of acromegaly, used as either primary or adjunctive therapy. In particular, SA are effective in inducing the biochemical remission of the disease and tumor shrinkage, although only few cases of complete disappearance of the pituitary tumo...

journal_title：European journal of endocrinology

authors： Auriemma RS,Galdiero M,Grasso LF,Vitale P,Cozzolino A,Lombardi G,Colao A,Pivonello R

更新日期：2010-05-01 00:00:00

abstract：:We report on a 15-year-old girl who had presented with acute onset central diabetes insipidus at the age of 8 years; this was followed by growth failure due to acquired growth hormone deficiency. Initial magnetic resonance imaging showed a uniformly enlarged pituitary stalk and absence of posterior pituitary hyperinte...

journal_title：European journal of endocrinology

authors： Maghnie M,Genovese E,Sommaruga MG,Aricò M,Locatelli D,Arbustini E,Pezzotta S,Severi F

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVE:Limited data exist concerning the presence of polycystic ovary syndrome (PCOS) in premenopausal women with nonalcoholic fatty liver disease (NAFLD). We aimed to investigate the prevalence of PCOS in overweight and obese premenopausal women with NAFLD. DESIGN:Prospective, observational, and cross-sectional st...

journal_title：European journal of endocrinology

authors： Vassilatou E,Vassiliadi DA,Salambasis K,Lazaridou H,Koutsomitopoulos N,Kelekis N,Kassanos D,Hadjidakis D,Dimitriadis G

更新日期：2015-12-01 00:00:00